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| | Myoglobin Test AHealthyMe.com |
 | | Myoglobin is one of the first tests done to determine if a person with chest pain is having a heart attack, as it may be one of the first blood tests to become abnormal. | | | Myoglobin holds oxygen inside heart and skeletal muscle (muscles that attach to and move bones). | | | It is the first marker to rise after chest pain begins. |
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http://www.ahealthyme.com/topic/topic100587189
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| | Use of Measurements of Myoglobin and Cardiac Troponins in the Diagnosis of Acute Myocardial Infarction |
| | Myoglobin may be most helpful when used in conjunction with other cardiac markers in the rapid determination of AMI, especially in patients with atypical chest pain or nonspecific ECG changes. | | | When myoglobin levels are measured at 2-hour intervals from the onset of chest pain, the sensitivity and specificity of myoglobin assays increase significantly. | | | The sensitivity of myoglobin tests increased from 50% to 60% for the blood sample obtained when the patient arrived in the emergency department after the onset of chest pain, to 100% for the second blood sample obtained 2 hours later. |
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http://www.aacn.org/aacn/jrnlccn.nsf/c54ad59fdf5d6228882565a0006a1369/5a2783b7a758d435882567300061f9f2?OpenDocument
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| | Myoglobin: The Test |
| | Myoglobin levels are often used every 2-3 hours for the first several hours after a patient who has chest pain comes to the emergency room. | | | If myoglobin does not increase after about 5 hours, a heart attack is very unlikely, unless the chest pain started more than a day before. | | | When it is ordered, it is ordered with troponin to assess persons with chest pain who are suspected of having a heart attack. |
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http://www.labtestsonline.org/understanding/analytes/myoglobin/test.html
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| | Myoglobin protein (ab9926) datasheet |
| | Only one form of myoglobin is expressed in cardiac and skeletal muscles. | | | Myoglobin is not so cardiac specific as cTnI or cTnT. | | | Nowadays it still is very commonly used in clinical practice as an early marker of AMI. |
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http://www.abcam.com/?datasheet=9926
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| | Myoglobin [MYO] |
| | Myoglobin levels are not useful for diagnosis of acute myocardial infarction except for early diagnosis, less than 6 hours after onset of chest pain, in outpatients with no other known muscle injury. | | | Myoglobin levels can be increased in any condition resulting in muscle damage, skeletal or cardiac muscle. | | | Specimens from patients who have received preparations of mouse monoclonal antibodies for diagnosis or therapy may contain human anti-mouse antibodies (HAMA). |
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http://depts.washington.edu/labweb/test/bclim/myoglobin.html
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| | MYOGLOBIN |
| | Normal serum myoglobin should be 0 (negative) to 85 ng/ml. | | | Myoglobin provides exercising muscles with an additional oxygen source. | | | Myoglobin is an oxygen binding protein found in cardiac and skeletal muscle. |
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http://www.medhelp.org/glossary/new/gls_2982.htm
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| | Myoglobin - Wikipedia, the free encyclopedia |
| | Myoglobin is a sensitive marker for muscle injury, making it a potential marker for myocardial infarction in patients with chest pain. | | | Myoglobin is the putative protein that causes acute renal failure in rapid breakdown of muscle (e.g. | | | In 1957, John Kendrew and associates successfully determined the structure of myoglobin by high-resolution X-ray crystallography. |
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http://en.wikipedia.org/wiki/Myoglobin
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| | TUTORIAL: Myoglobin |
| | What animals do YOU think have myoglobin thats the most like the myoglobin that we humans have? | | | And how can the oxygen stay in the muscles so that we can use them and get energy from them? | | | Look within this box, and toward the top of the list you should see |
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http://www.bioquest.org/bioinformatics/module/tutorials/Myoglobin
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| | Antarctica |
| | In addition to examining which species of icefish have myoglobin, Dr. Sidell is also working on how myoglobin allows icefish to be more efficient in their use and transport of oxygen within the body. | | | Icefish all lack hemoglobin and Dr. Sidell is researching the myoglobin that is found in some, but not all, species of icefish. | | | Hemoglobin and myoglobin pick up oxygen from the lungs and transport it to the muscles and tissues. |
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http://octopus.gma.org/onlocation/past.html
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| | [No title] |
| | Boyer, S. Similar incidence and non-randomness among human myoglobin and hemoglobin mutants in general populations: implications for the study of myoglobin in muscle disease. | | | Although heart and soleus muscles were depigmented, they functioned normally in standard in vitro assays of muscle performance across a range of work conditions and oxygen availability. | | | The human myoglobin gene: a third dispersed globin locus in the human genome. |
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http://srs.sanger.ac.uk/srs5bin/cgi-bin/wgetz?-e+[omim-id:160000]
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| | Cardiac Markers and Chest Pain Diagnosis: Myoglobin |
| | In addition, Myoglobin has an excellent negative predictive value in the evaluation of patients with acute chest pain. | | | Myoglobin, a low molecular weight heme protein found in cardiac and skeletal muscle, is valuable in the early evaluation of chest pain patients. | | | While Myoglobin is not specific to cardiac muscle, it is useful in the detection of MI in the absence of skeletal muscle trauma or other factors that may be associated with a noncardiac-related increase. |
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http://www.chestpainperspectives.com/content/misl_pages/myo.cfm
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| | [No title] |
| | Serum myoglobin determinations in the assessment of acute myocardial infarction. | | | Introduction Myoglobin is a heme protein found in both cardiac and skeletal muscle. | | | A test result that is inconsistent with the clinical picture and patient history should be interpreted with caution. |
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http://www.rapidtest.com/Myoglobin_1667.doc
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| | Myoglobin Rapid Slide Test |
| | When the serum sample is added to the sample pad, it moves through the conjugate pad and mobilizes gold anti-myoglobin conjugate that is coated on the conjugate pad. | | | Therefore, myoglobin is better suited for the early diagnosis of acute myocardial infarction AMI). | | | Due to its low molecular weight, myoglobin is released more rapidly when muscle cells are damaged than other markers. |
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http://www.metachem.co.uk/Myoglobin.htm
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| | Evolutionary implications: myoglobin-like proteins found in ancient microorganisms |
| | Myoglobin, a member of the hemoglobin family found in vertebrates, gives muscles their red color. | | | Porphyrin ring describes the molecular structure common to hemoproteins and chlorophylls. | | | Hemoglobin is also found in the root nodules of some plants. |
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http://www.eurekalert.org/pub_releases/2000-02/UoH-Eimp-0102100.php
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| | Myoglobin and Hemoglobin |
| | In addition, the quaternary structure of hemoglobin leads to physiologically important allosteric interactions between the subunits, a property lacking in monomeric myoglobin which is otherwise very similar to the | | | Myoglobin and hemoglobin are hemeproteins whose physiological importance is principally related to their ability to bind molecular oxygen. | | | Myoglobin is a monomeric heme protein found mainly in muscle tissue where it serves as an intracellular storage site for oxygen. |
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http://www.indstate.edu/thcme/mwking/hemoglobin-myoglobin.html
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| | Untitled Document |
| | You can see that the peptide twists and turns to form a relatively compact globular structure. | | | This tutorial will use hemoglobin and myoglobin to illustrate some general aspects of secondary, tertiary and quaternary structure in proteins. | | | The richest source of myoglobin is the muscle of aquatic diving mammals, such as seals or whales, since these tissues need a very rich store of oxygen to see them through long anoxic periods during a dive. |
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http://ase.tufts.edu/biology/MolecVisual/bio13/rightB13hemo.html
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| | Exploring Myoglobin: An Example of Bioinformatics |
| | You can see that they look very much alike. | | | Myoglobin is an oxygen carrying molecule found in the muscles of essentially all animals, as distantly related as humans and fish. | | | As part of this work, myoglobin was used as a probe -- just as described in this exercise. |
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http://peptide.ncsa.uiuc.edu/nsf/myoglobin01.html
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| | Myoglobin Oxygen Binding Curves Determined by Phosphorescence Quenching of Palladium Porphyrin |
| | Index Headings: Myoglobin; Hemeprotein; Porphyrin; Phosphorescence; Oxygen; Absorption spectroscopy; UV-visible spectroscopy. | | | J.J. Kelly, K.A. Kelly, S.A. Hartley and C.H. Barlow (1991) Myoglobin oxygen binding curves determined by phosphorescence quenching of palladium porphyrin. | | | Myoglobin oxygenation curves were obtained from the spectra by two full-spectrum procedures, singular value decomposition (SVD) and curve fitting, and by the traditional dual-wavelength isosbestic method. |
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http://www.evergreen.edu/biophysics/papers/myo.htm
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| | Simultaneous Determination of Hemoglobin and Myoglobin Oxygen Binding Curves by Spectral Curve Fitting |
| | Index Headings: Hemoglobin; Myoglobin; Hemeprotein; Porphyrin; Phosphorescence; Oxygen; Absorption spectroscopy. | | | C.H. Barlow, K.A. Kelly and J.J. Kelly (1992) Simultaneous determination of hemoglobin and myoglobin oxygen binding curves by spectral curve fitting. | | | Solution oxygen concentrations were computed from measurements of phosphorescence decay of a soluble palladium porphyrin using the Stern-Volmer quenching relationship. |
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http://www.evergreen.edu/biophysics/papers/hbmb.htm
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| | Myoglobin, Serum |
| | Serum myoglobin was found also in 50% of patients with acute coronary insufficiency. | | | Serum myoglobin is generally detectable earlier than is CK or CK-MB increase in patients with acute myocardial infarction. | | | It is increased in azotemic subjects and not effected by dialysis. |
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http://www.labcorp.com/datasets/labcorp/html/chapter/mono/sr003100.htm
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| | Serum Myoglobin - Page 1 - HeartCenterOnline: |
| | Higher serum myoglobin levels mean that the patient has severe muscle damage somewhere in the body. | | | Elevated serum myoglobin may also indicate skeletal muscle damage or a variety of other conditions. | | | This test has been largely replaced by other tests, such as those for cardiac enzymes. |
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http://heart.healthcentersonline.com/bloodtest/serummyoglobin.cfm
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| | myoglobin on Encyclopedia.com |
| | Myoglobin is found abundantly in man only in cardiac muscle, which, by virtue of its essential function, must possess the capacity for continued activity when environmental oxygen concentrations are low. | | | Myoglobin has been investigated intensely and is the first protein molecule to have been completely described in terms of its three-dimensional geometry. | | | The distribution of myoglobin among the higher animals is a reflection of its physiological function. |
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http://www.encyclopedia.com/html/m1/myoglobi.asp
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| | myoglobin |
| | with myoglobin than it does with hemoglobin, favouring the transfer of oxygen from blood to muscle cells. | | | Myoglobin has been of great importance in the elucidation of protein structure. | | | Diving mammals such as seals and whales are able to remain submerged for long periods because they have greater amounts of myoglobin in their muscles than other animals do. |
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http://www.britannica.com/nobel/micro/412_66.html
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| | Meat Color |
| | Vitamin E can be fed to livestock to increase the alpha-tocopherol concentration in muscle. | | | (1) To demonstrate the relationship between myoglobin and meat color. | | | reduced myoglobin ---> oxymyoglobin ---> metmyoglobin ---> reduced myoglobin ---> etc. |
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http://savell-j.tamu.edu/color.html
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| | PDB Molecule of the Month: Myoglobin |
| | After years of arduous work, John Kendrew and his coworkers determined the atomic structure of myoglobin, laying the foundation for an era of biological understanding. | | | Its job is to store oxygen, for use when muscles are hard at work. | | | Any discussion of protein structure must necessarily begin with myoglobin, because myoglobin is where the science of protein structure really began. |
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http://www.rcsb.org/pdb/molecules/mb1.html
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| | Myoglobin |
| | • One of the most important proteins in the human body is MYOGLOBIN. | | | Myoglobin is found in muscle tissue, where it binds oxygen, helping to provide extra oxygen to release energy to power muscular contractions. | | | Click Here for a copy of our Guide to Searching the Human Genome |
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http://www.millerandlevine.com/guide/myoglobin.html
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| | Myoglobin antibodies from RDI Divison of Fitzgerald Industries Intl |
| | Application: Detection of human cardiac myoglobin in immunoassay. | | | Although the amount of sodium azide is very small appropriate care must be taken when handling this product. | | | These clones have been derived from hybridization of SP2/0 myeloma cells with spleen cells of balb/c mice immunized with human cardiac myoglobin |
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http://www.researchd.com/miscabs/trk4m23.htm
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| | ninemsn Encarta - Protein |
| | In 1960, John Kendrew and Max Perutz used X-ray diffraction to determine the three-dimensional structures of the oxygen-carrying molecules myoglobin and haemoglobin. | | | These studies led to the concept that linear chains of amino acids fold up to give protein molecules that have always precisely the same structure and function. | | | At the same time, on the other side of the Atlantic, scientists were probing the three-dimensional structure of protein molecules. |
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http://au.encarta.msn.com/encyclopedia_761565946/Protein.html
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| | Myoglobin (oxy) |
| | Myoglobin (1mbo.pdb) is the monomeric oxygen-carrier protein found in muscle tissue. | | | Back to the Protein Structure List or the Rainbow Diagrams. | | | The amino and carboxyl termini of the protein are labeled. |
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http://www.bio.cmu.edu/Courses/03231/ProtStruc/1mbo.htm
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| | Casegroup -- Sperm-whale myoglobin |
| | Solution structure of carbonmonoxy myoglobin determined from NMR distance and chemical shift constraints. | | | Backbone of sperm whale myoglobin, refined with NOESY and chemical shift based restraints. |
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http://www.scripps.edu/mb/case/casegr-sh-4.4.html
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| | MYOGLOBIN |
| | Myoglobin ist ein Häm-haltiges Molekül, das eine hohe Affinität zu Sauerstoff hat und in hoher Konzentration (bis etwa 100µM) in Herz- und Skelettmuskelzellen von Säugern vorkommt, daher auch die rote Farbe. |
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http://www.toonorama.com/encyclopedia/M/Myoglobin
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