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Topic: Myofibril



  
 ARS Publication request: TECHNICAL NOTE: COMPARISON OF MYOFIBRIL FRAGMENTATION INDEX FROM FRESH AND FROZEN PORK AND ...
MFI measures the level of breakdown of the muscle proteins that hold the myofibrils together and it is strongly associated with indices of meat tenderness.
The reason for this tenderization is breakdown of proteins that are responsible for structural integrity of myofibrils.
A method to quantify the extent of postmortem tenderization is called the Myofibril Fragmentation Index (MFI).
http://ars.usda.gov/research/publications/publications.htm?SEQ_NO_115=113548   (413 words)

  
 Titin-based contribution to shortening velocity of rabbit skeletal myofibrils -- Minajeva et al. 540 (1): 177 -- The ...
With a myofibril suspended between needles, leupeptin was washed out from the buffer by changing the solution six times.
Because there is no reason to suppose that such interactions are absent in skeletal muscle sarcomeres, we conclude that the most likely scenario is one in which passive elastic recoil is opposed by viscous forces originating in weak actin-titin associations.
Myofibrils were isolated from freshly excised rabbit psoas skeletal muscle as described previously (Linke et al.
http://jp.physoc.org/cgi/content/full/540/1/177   (7613 words)

  
 Assembly of thick filaments and myofibrils occurs in the absence of the myosin head
The likely explanation for the myofibril assembly defects we observe is that headless myosin is deficient in its interactions with other components of the sarcomere.
Our results demonstrate that the myosin head is dispensable for thick filament assembly and many aspects of myofibrillogenesis, but that the interaction of the head with other myofibrillar components is likely to be required for defining the precise geometry of the sarcomere.
This is consistent with our earlier study demonstrating that adult and embryonic MHCs display isoform-specific properties in stabilizing myofibril structure (Wells et al., 1996).
http://www.nature.com/emboj/journal/v18/n7/full/7591607a.html   (8493 words)

  
 Measurement of Thin Filament Lengths by Distributed Deconvolution Analysis of Fluorescence Images -- Littlefield and ...
Myofibrils were examined by wide field epifluorescence on a Zeiss Axioskop with a 63× plan-apochromat lens (NA 1.40) (Zeiss,
phallacidin staining was analyzed in relaxed myofibrils or when
on the repeating structure of myofibrils to determine an average
http://www.biophysj.org/cgi/content/full/82/5/2548   (8965 words)

  
 Myofibril Composition
Putting the myofibrils back into the muscle fiber...
A chain of sarcomeres, like the one I drew above in point #3, that runs from one end of the muscle fiber to the other end of the muscle fiber is a myofibril.
Putting the myofibrils back into the muscle fiber
http://distance.stcc.edu/AandP/AP/AP1pages/Units5to9/Unit7/myofibri.htm   (1536 words)

  
 Targeting and functional role of N-RAP, a nebulin-related LIM protein, during myofibril assembly in cultured chick ...
(B) The method for quantitating myofibril content in individual cardiomyocytes: the periphery of the transfected cardiomyocyte stained with
Laboratory of Muscle Biology, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892, USA
We quantitated the functional effects of the GFP fused N-RAP
http://jcs.biologists.org/cgi/content/full/114/23/4229   (5194 words)

  
 Measurement of Nucleotide Exchange Rate Constants in Single Rabbit Soleus Myofibrils during Shortening and Lengthening ...
in our experiments by breakage of the myofibril.
a constant area was analyzed to include the whole myofibril.
Previous control experiments in which a myofibril was allowed
http://www.biophysj.org/cgi/content/full/78/2/918   (4626 words)

  
 Thin filaments elongate from their pointed ends during myofibril assembly in Drosophila indirect flight muscle -- ...
Overexpression of 43-kD SPDO during early- or late-myofibril assembly affects myofibril structure without affecting muscle function.
the diameter of the affected cores measured from myofibrils
in the core and periphery of myofibrils from both heat-shocked
http://www.jcb.org/cgi/content/full/155/6/1043   (7134 words)

  
 Delgado et al., August 2001
Discovery that a significant proportion of μ-calpain becomes associated with the myofibril during postmortem storage raised an attractive new explanation for the mechanism of postmortem tenderization.
Hence, it seems unlikely that the myofibril-bound calpain has a significant role in postmortem tenderization of ovine longissimus.
Over 25% of total μ-calpain was bound to myofibrils from at-death muscle, and this increased to ~40% after 1 d postmortem.
http://www.asas.org/jas/abs/2001/a0182097.htm   (514 words)

  
 Protein Kinase C-Mediated Desmin Phosphorylation Is Related to Myofibril Disarray in Cardiomyopathic Hamster Heart -- ...
Protein Kinase C-Mediated Desmin Phosphorylation Is Related to Myofibril Disarray in Cardiomyopathic Hamster Heart
The present study has been undertaken to examine the
role of desmin phosphorylation in myofibril disarray observed
http://www.ebmonline.org/cgi/content/abstract/227/11/1039   (327 words)

  
 Light microscopy and image analysis of thin filament lengths utilizing dual probes on beef, chicken, and rabbit ...
myofibrils from various muscles and species in order to visualize
Ultrastructure of skeletal muscle fibers studied by a plunge quick freezing method: Myofilament lengths.
Images of myofibrils from different beef muscles are shown in
http://www.animal-science.org/cgi/content/full/82/5/1445   (2699 words)

  
 myofibril --  Encyclopædia Britannica
All animal movement depends on the use of muscles.
Each muscle fiber consists of rod-shaped myofibrils (see Muscles).
Skeletal muscle is made up of muscle fibers.
http://www.britannica.com/eb/article-9054547   (583 words)

  
 LARGE MYO PICT
In the nascent myofibril, the alpha-actinin-rich Z-bodies have begun to laterally associate, possibly through interaction with titin.
Overlapping muscle myosin II filaments bound to titin are present at this stage.
In the mature myofibril the alpha-actinin containing Z-bodies fuse to form the wide lateral arrays of mature Z-bands; nonmuscle myosin IIB is lost whereas muscle myosin filaments are now aligned into A-bands.
http://www.med.upenn.edu/sanger/largemyo.html   (126 words)

  
 myofibril - definition of myofibril by the Free Online Dictionary, Thesaurus and Encyclopedia.
Any of the threadlike fibrils that make up the contractile part of a striated muscle fiber.
myofibril - one of many contractile filaments that make up a striated muscle fiber
This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional.
http://www.thefreedictionary.com/myofibril   (142 words)

  
 Pathogenesis of Dilated Cardiomyopathy : Molecular, Structural, and Population Analyses inTropomodulin-Overexpressing ...
Jindal N, Talwar KK, Chopra P: Ultrastructural and histological study of endomyocardial biopsies from patients of dilated cardiomyopathy: a comparative evaluation and their clinical correlation.
by confocal microscopy, the extent of myofibril degeneration observed
of myofibrils probably contributes to degeneration of the myocardial cytoskeleton
http://ajp.amjpathol.org/cgi/content/full/155/6/2101   (7051 words)

  
 Energy Citations Database (ECD) - Energy and Energy-Related Bibliographic Citations
Energy Citations Database (ECD) Document #5212711 - Relationships of valve histology and mitochondrial and myofibril volume densities to hypertrophy of copper-deficient rat hearts
Relationships of valve histology and mitochondrial and myofibril volume densities to hypertrophy of copper-deficient rat hearts
Availability information may be found in the Availability, Publisher, Research Organization, Resource Relation and/or Author (affiliation information) fields and/or via the "Full-text Availability" link.
http://www.osti.gov/energycitations/product.biblio.jsp?osti_id=5212711   (146 words)

  
 Definition of halide,menopause,myofibril,confusion,external ...
Medical term myofibril Define myofibril Meaning of myofibril What does myofibril mean?
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http://www.english-test.net/mcat/vocabulary/words/091/mcat-definitions.php   (1084 words)

  
 Myofibril - Wikipedia, the free encyclopedia
Myofibrils (obsolete term: sarcostyles) are cylindrical organelles, found within muscle cells.
A diagram of the structure of a Myofybril
The muscle cell is nearly filled with myofibrils running parallel to each other on the long axis of the cell.
http://en.wikipedia.org/wiki/Myofibril   (664 words)

  
 T tubule - definition of T tubule in the Medical dictionary - by the Free Online Medical Dictionary, Thesaurus and ...
The tubule that passes in a transverse manner from the sarcolemma across a myofibril of striated muscle.
http://medical-dictionary.thefreedictionary.com/T+tubule   (90 words)

  
 Mutations in the motor domain modulate myosin activity and myofibril organization -- Wang et al. 116 (20): 4227 -- ...
correlate with changes in myofibril organization of live cardiomyocytes.
We have investigated the functional impact on cardiac myofibril
This article has been cited by other articles:
http://jcs.biologists.org/cgi/content/abstract/116/20/4227   (284 words)

  
 Encyclopedia article on Muscle [EncycloZine]
Muscle is composed of muscle cells (sometimes known as "muscle fibers").
Muscle cells are bound together by perimysium into bundles called fascicules; the bundles are then grouped together to form muscle, which is lined by epimysium.
Within the cells are myofibrils; myofibrils contain sarcomeres, which are composed of actin and myosin.
http://encyclozine.com/Muscle   (986 words)

  
 Muscle Structure & Function: Part 3
The sarcomere is the name given to the "unit pattern" that is repeated along the myofibril.
Along the length of each myofibril, the sets of filaments interlock, forming the alternate regions in which thick or thin filaments are either present or overlap.
These structures run the length of the fiber and are 1 or 2 micrometers in diameter.
http://www.scnf.org/riley3.html   (2875 words)

  
 MYOFIBRIL
Under the light microscope skeletal muscle has a striated appearance, as seen in the picture of a myofibril:
The striated appearance is due to the arrangement of two sets of interdigitating arrays of filaments.
http://chroma.med.miami.edu/pharm/faculty/jdp/muscle/sld006.htm   (34 words)

  
 The Low Molecular Weight GTPase Rho Regulates Myofibril Formation and Organization in Neonatal Rat Ventricular ...
The Low Molecular Weight GTPase Rho Regulates Myofibril Formation and Organization in Neonatal Rat Ventricular Myocytes.
increases in the organization of myofibrils into sarcomeric units.
roles in regulating the organization of actin-myosin myofibrils
http://www.jbc.org/cgi/content/full/273/13/7725   (4673 words)

  
 Muscular System - A Great Resource of Information
The Yuckiest Site on the Net - The Muscular System Check out this fun site that offers a brief summary of the...
A sarcomere is a section of a myofibril.
http://www.totallymuscle.com/muscularsystem   (1513 words)

  
 MSN Encarta - Dictionary - myofibril definition
Click here to search all of MSN Encarta
Search for "myofibril" in all of MSN Encarta
http://encarta.msn.com/dictionary_1861632190/myofibril.html   (67 words)

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