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Topic: Multicellular


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 Multicellular stage, Animals
Multicellular animals direct behavior at other objects by the contraction of muscle cells located where the muscles are needed to change the body’s shape, and neurons generate behavior by controlling the relevant muscles.
After constructing the queen’s body, her body is used to construct the other members, and the queen becomes the center of a multisomatic structure in which pheromones are used to coordinate the behavior of her multicellular offspring (the same mechanism used to coordinate cells at the multicellular level).
Thus, the organism's behavior as a whole depends mainly on the biological behavior guidance system at the multicellular level, and it reproduces as a whole.
http://www.twow.net/ObjText/OtkCbGeRRS04B.htm   (5002 words)

  
 From Single Cells to Multicellular Organisms 18
During evolution many of the developmental devices that evolved in the simplest multicellular organisms have been conserved as basic principles for the construction of their more complex descendants.
This principle, applying at first to simple associations of cells, has been taken to an extreme in the multicellular organisms we see today.
Innovations in movement, sensory detection, communication, social organization - all enabled eucaryotic organisms to compete, propagate, and survive in ever more complex ways.
http://www.ncbi.nlm.nih.gov/books/bv.fcgi?db=Books&rid=cell.section.61   (3950 words)

  
 Gould: The Evolution of Life on the Earth
These thin, quilted, sheetlike organisms may be ancestral to some modern forms but may also represent a separate and ultimately failed experiment in multicellular life.
If complexity is such a good thing, and multicellularity represents its initial phase in our usual view, then life certainly took its time in making this crucial step.
Humans arose, rather, as a fortuitous and contingent outcome of thousands of linked events, any one of which could have occurred differently and sent history on an alternative pathway that would not have led to consciousness.
http://www.brembs.net/gould.html   (4835 words)

  
 Multicellular Organisms
The more complex multicellular organisms cope with the problem of being vulnerable to changes in the environment by surrounding their individual cells with fluid that is separated from the environment by a barrier such as the skin.
By maintaining the internal environment constant, multicellular organisms are less vulnerable to changes in the external environment.
This is the reason multicellular organisms have developed transport systems such as the circulatory system.
http://www3.fhs.usyd.edu.au/bio/homeostasis/Multicell_organisms.htm   (257 words)

  
 Kota Miura
Multicellular movement is also reachable with current microscopic techniques.
A large body of results suggest that cyclic AMP-mediated cell-cell signaling is the mechanism coordinating multicellular movement.
Multicellular organism behaves as a single organism because cells within the organism move in a coordinated manner.
http://www.embl-heidelberg.de/~miura/res_projectMulticellularBio.html   (1223 words)

  
 Antiadhesive antibodies targeting E-cadherin sensitize multicellular tumor spheroids to chemotherapy in vitro -- Green ...
and related signaling pathways in multicellular spheroids of
be used to overcome, at least in part, multicellular resistance
Previous studies from our laboratory have shown that multicellular
http://mct.aacrjournals.org/cgi/content/full/3/2/149   (6352 words)

  
 Cell-cell adhesion and signal transduction during Dictyostelium development -- Coates and Harwood 114 (24): 4349 -- ...
After extension to form the first finger, the developing structure either immediately forms a fruiting body, the process of culmination or forms a motile slug that migrates to seek conditions favourable for culmination.
fail to enter the multicellular phase of development (Ponte et al., 1998).
they are not essential to establish the basic multicellular
http://jcs.biologists.org/cgi/content/full/114/24/4349   (6414 words)

  
 Natural History: All for one and one for all: multicellular organisms have arisen more than once, each time through an ...
And by studying how multicellular creatures such as volvox took that step, scientists can gather clues about how our own bodies evolved.
Of course, pathways need to be kept open to ensure that the individual cells are bathed in the necessary fluids.
Because multicellularity is an experiment that's been run many times in the history of life, scientists may be able to discover some universal rules for how it comes about.
http://www.findarticles.com/p/articles/mi_m1134/is_1_111/ai_82803329   (1527 words)

  
 A new theory of the evolution of cooperation
The mechanisms do not disclose a general method for organising cooperation amongst self-interested components that would work for any living processes in any circumstances.
But as a theory, kin selection has been very successful.
Multicellular organisms had to introduce additional controls to prevent mitochondria competing within them and undermining cooperation.
http://users.tpg.com.au/users/jes999/5.htm   (9079 words)

  
 Idle Theory: Multicellular Life
It may be asked how it is, if there is such a constant need for life to organize itself first into complex multicellulars, and then into societies of multicellulars, that there are any unicellular forms of life still extant?
Every human being carries many different species of them, living off discarded skin, or within the intestinal tract.
This is that it has been argued that multicellulars are more idle than unicellulars, and that life tends to be difficult for unicellulars.
http://www.idlex.freeserve.co.uk/idle/evolution/idlev2a/idlev-2a.html   (4582 words)

  
 Macroautophagy Is Required for Multicellular Development of the Social Amoeba Dictyostelium discoideum -- Otto et al. ...
Macroautophagy Is Required for Multicellular Development of the Social Amoeba Dictyostelium discoideum -- Otto et al.
Articles by Otto, G. Articles by Kessin, R. Macroautophagy Is Required for Multicellular Development of the Social Amoeba Dictyostelium discoideum
http://www.jbc.org/cgi/content/abstract/278/20/17636   (726 words)

  
 Engineering biological structures of prescribed shape using self-assembling multicellular systems -- Jakab et al. 101 ...
Engineering biological structures of prescribed shape using self-assembling multicellular systems -- Jakab et al.
Engineering biological structures of prescribed shape using self-assembling multicellular systems
in suspension or on nonadhesive surfaces, various multicellular
http://www.pnas.org/cgi/content/full/101/9/2864   (3768 words)

  
 Evolution of Plants Lecture
This involves an alternation between a multicellular diploid sporophyte which, through meiosis produces haploid spores which in turn undergo mitosis to form a multicellular gametophyte which makes, what else, gametes.
Plants are multicellular photosynthetic organisms that are believed to have
The multicellular diploid embryo is housed within a multicellular gametophyte (in algae the embryo is separate from the haploid tissue).
http://home.earthlink.net/~dayvdanls/PlantEvol.html   (611 words)

  
 United States Patent Application: 0040092471
As mentioned above, a critical feature of the subject methods is that the vector or vectors comprising the various elements of the Sleeping Beauty transposon system, e.g.
The method according to claim 1, wherein said multicellular organism is a vertebrate.
The method according to claim 12, wherein said multicellular organism is a vertebrate animal.
http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PG01&p=1&u=/netahtml/PTO/srchnum.html&r=1&f=G&l=50&s1="20040092471".PGNR.&OS=DN/20040092471&RS=DN/20040092471   (9174 words)

  
 Introductory Biology Courseware (111)- Protista
Biologists are unsure whether ediacaran fauna represent early representatives of those two phyla or a lineage which left no living descendents (the basic body plans are considerably different from extant forms).
There are a diversity of forms of chlorophytes, with some being simple uni- or multicellular sessile forms, some being motile, and some being colonial or large multicellular forms.
Either the haploid organism, the diploid organism, or both may also reproduce
http://tidepool.st.usm.edu/crswr/111protists.html   (1197 words)

  
 Single Cell Vs Multicellular - The best cell products, sites and information on the web today!
Trans-bonded pairs of E-cadherin exhibit a remarkable hierarchy of mechanical strengths -- Perret et al.
The transition of the single-cell organism to the multicellular organism was accompanied by differentiation of...
in humans and other multicellular organisms (plants and animals) also...
http://cell.epcgold.com/index.php?k=single-cell-vs-multicellular   (962 words)

  
 The Social Superorganism and its Global Brain
The fact that complex organisms, like our own bodies, are built up from individual cells, led to the concept of superorganism.
Society can be viewed as a multicellular organism, with individuals in the role of the cells.
If cells aggregate to form a multicellular organism, then organisms might aggregate to form an organism of organisms: a superorganism.
http://pespmc1.vub.ac.be/suporgli.html   (644 words)

  
 Protoctista
In the last two decades, however, the basis for classifying single-celled organisms separately from multicellular ones has weakened.
It has become evident that multicellularity evolved many times from unicellular forms - many multicellular organisms are far more closely related to certain unicells than they are to any other multicellular organisms.
For example, the ciliates, which are unicellular microbes, include at least one species that forms a sorocarp, a multicellular spore-bearing structure; euglenoids, chrysophytes, and diatoms also have multicellular derivatives.
http://www.bio.umass.edu/biology/conn.river/protoc.html   (566 words)

  
 Multi-cell Organisms
This evolutionary development seems to indicate that earlier life tried to construct the multicellular body from the simpler cell unit in haploid state.
Multicellular organism development involves many processes as illustrated in the simple case of slime moulds.
The result is that all multicellular organisms, from small algae and fungi to elephants and human, have a unicellular stage and a large stage of varying dimensions in their life cycle.
http://universe-review.ca/F10-multicell.htm   (14873 words)

  
 Stephen Jay Gould, "Planet of the Bacteria" 1996
The first multicellular creatures—marine algae—enter the stage soon afterward, but these organisms bear no genealogical relationship to our primary interest: the history of animal life.
Oxygen, the most essential constituent of the atmosphere for human needs, now maintains itself primarily through release by multicellular plants in the process of photosynthesis.
The Earth's original atmosphere apparently contained little or no free oxygen, and this otherwise unlikely element both arose historically and is now maintained by the action of organisms.
http://www.stephenjaygould.org/library/gould_bacteria.html   (3207 words)

  
 Modeling Chemotactic Cell Sorting during Dictyostelium discoideum Mound Formation -- Vasiev and Weijer 76 (2): 595 -- ...
A gradient method for the quantitative analysis of cell movement and tissue flow and its application to the analysis of multicellular Dictyostelium development.
Coordinated cell movement is a major mechanism of the multicellular development of most organisms.
the role of myosin-II in the transition from the unicellular to the multicellular phase.
http://www.biophysj.org/cgi/content/full/76/2/595   (6398 words)

  
 phyto1
So understanding the relationship between the two generations is important in the study of plant development.
Aside from the difference in ploidy level between the gametophyte and sporophyte, there may be some interesting parallels to draw with metamorphosis in insects and amphibians.
Unlike animals, plants have multicellular haploid and multicellular diploid stages in their life cycle.
http://zygote.swarthmore.edu/phyto1.html   (9393 words)

  
 A transcriptional profile of multicellular development in Dictyostelium discoideum -- Van Driessche et al. 129 (7): ...
The process is highly synchronous as most of the multicellular structures are at the same morphological stage at each time point (Sussman, 1987
a bone fide multicellular organism, capable of sensing its environment
Following the transition from unicellular to multicellular development,
http://dev.biologists.org/cgi/content/full/129/7/1543   (7498 words)

  
 Three-dimensional cell cultures: from molecular mechanisms to clinical applications -- Mueller-Klieser 273 (4): 1109 -- ...
of primary adult rat and human hepatocytes as multicellular spheroids.
experimental model of acute liver injury using multicellular spheroids
enzymes seem to be unaffected by multicellular growth conditions,
http://ajpcell.physiology.org/cgi/content/full/273/4/C1109   (6335 words)

  
 Protein Kinase C {lambda}/{iota} (PKC{lambda}/{iota}): A PKC Isotype Essential for the Development of Multicellular ...
): A PKC Isotype Essential for the Development of Multicellular Organisms
Protein Kinase C {lambda}/{iota} (PKC{lambda}/{iota}): A PKC Isotype Essential for the Development of Multicellular Organisms -- Suzuki et al.
http://jb.oupjournals.org/cgi/content/abstract/133/1/9   (582 words)

  
 A-signal production in Myxococcus xanthus
This change from a vegetative to developmental cycle involves many cell-cell interactions, and a putative developmental pathway exists, though not thoroughly understood.
Further molecular and genetic studies will undoubtedly hasten the explanation of this fascinating phenomenon, as they are an excellent opportunity to explore some of the most primitive examples of multicellularity in a prokaryotic system - where the power of molecular and genetic experiments is greatest.
Myxococcus xanthus, a gram-negative bacterium found usually in soil, is one of the most well characterized of the myxobacteria with respect to regulation of gene expression during development.
http://www.ucs.mun.ca/~barretta/homepage.html   (3481 words)

  
 Multicellular Parasites
They live in a large variety of tissues, though many are specialized to single tissues such as muscle, vein, brain, or intestine.
Helminths are eucaryotic, multicellular animals that are mostly parasitic of other animals.
Usually a parasite is considered to be something smaller than the host and therefore capable of parasitizing only one host at a time.
http://www.mansfield.ohio-state.edu/~sabedon/biol3050.htm   (253 words)

  
 INSIDE ANCIENT ANIMAL EMBRYOS AND ALGAE — COMPUTED TOMOGRAPHIC ANALYSIS OF NEOPROTEROZOIC MULTICELLULAR EUKARYOTES
Previous work on these fossils has been limited to examination of their three-dimensional external morphology using SEM or their two-dimensional internal morphology using thin-section observation.
600 Ma Doushantuo Formation provide critical information about the evolution of early multicellular organisms and exhibit spectacular cellular-level preservation.
All other forms of reproduction and/or transmittal are prohibited without written permission from GSA Copyright Permissions.
http://gsa.confex.com/gsa/2002AM/finalprogram/abstract_39474.htm   (476 words)

  
 Multicellular organisms
"The path from a unicellular condition to a multicellular one has been well-traveled.
Somehow the germ cells exchange proliferation by fission within the organism for reproduction by seed across generations, and the specialized somatic cells gain in reproductive opportunities by fission within the organism.
The path from multicellularity to cellular differentiation, however, proved a far less porous filter.
http://pespmc1.vub.ac.be/MULTICEL.html   (377 words)

  
 Tumor-induced angiogenesis studied in confrontation cultures of multicellular tumor spheroids and embryoid bodies grown ...
embryoid bodies and avascular multicellular spheroids as well
cultures of multicellular tumor spheroids and embryoid bodies
Spinner culture technique for cultivation of multicellular tumor spheroids
http://www.fasebj.org/cgi/content/full/15/6/995   (5923 words)

  
 Multicellular organism - Wikipedia, the free encyclopedia
Multicellular organisms must solve the problem of regenerating the whole from germ cells (i.e.
Multicellular organisms can suffer from cancer when cells fail to regulate their growth within the normal program of development.
Multicellular organisms are those organisms containing more than one cell, and having differentiated cells that perform specialized functions.
http://www.wikipedia.org/wiki/Multicellular   (165 words)

  
 UCMP Glossary: Life history
The sporophyte is multicellular and develops from a zygote.
haploid-diploid life cycle -- Occurs when a multicellular diploid phase, or sporophyte, alternates with a multicellular haploid phase, or gametophyte.
development -- The process by which a multicellular organism is produced from a single cell.
http://www.ucmp.berkeley.edu/glossary/gloss6lifehist.html   (858 words)

  
 Multicellular Organization Laboratory
@@@@How the shape and behavior of multicellular organisms are determined by genetic information is one of the most fundamental problems in biology.
http://www.nig.ac.jp/labs/MultiOrg/home1e.html   (197 words)

  
 Cells the Fundamental Unit of Life
In multicellular organisms individual groups of cells have become specialised to perform particular roles in the life of the organism.
In simple multicellular organisms such as sponges all the cells are very similar, in more complicated multicellular organisms the degree of specialisation of cells is much greater resulting in cells that are very different from one another.
The life of the organism is dependant on the correct working of all the different groups, each of which is dependant on all the others for its continued existence.
http://www.earthlife.net/cells.html   (1479 words)

  
 Growth Stimulation Versus Induction of Cell Quiescence by Hydrogen Peroxide in Prostate Tumor Spheroids Is Encoded by ...
Culture Technique of Multicellular Spheroids-- The human prostate cancer cell line DU-145 was kindly provided by Dr. J.
At least 15 tumor spheroids were evaluated for the respective experimental condition in each experiment.
At least 15 tumor spheroids were evaluated for the respective experimental conditions in each experiment.
http://www.jbc.org/cgi/content/full/274/39/27759   (4577 words)

  
 IFI U.S. Class Hierarchies
The nonhuman animal is a model for human disease 800-010.000.
The nonhuman animal is a model for human disease 800-011.000.
The nonhuman animal is a model for human disease 800-012.000.
http://www.ificlaims.com/IFICLS/uch/800.htm   (3465 words)

  
 The DC electrical-field-induced Ca2+ response and growth stimulation of multicellular tumor spheroids are mediated by ...
of multicellular tumor spheroids may arise from the stimulation
response revealed that treatment of multicellular tumor spheroids
Inhibition of the electrical-field-evoked Ca response by anion channel inhibitors.
http://jcs.biologists.org/cgi/content/full/115/16/3265   (5579 words)

  
 multicellular - definition of multicellular by the Free Online Dictionary, Thesaurus and Encyclopedia.
Having or consisting of many cells: multicellular organisms.
multicellular - consisting of many cells; "multicellular organisms"
This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional.
http://www.thefreedictionary.com/multicellular   (135 words)

  
 ALGAE AND FUNGUSLIKE PROTISTS
Although most species of algae are unicellular, some are large, multicellular organisms.
Algae differ from protozoa, which are also classified in the Kingdom Protista, in that they manufacture their food through the process of photosynthesis.
FOUR Types of Algae are recognized, based on the following Body Structures: UNICELLULAR, COLONIAL, FILAMENTOUS, AND MULTICELLULAR.
http://www.sirinet.net/~jgjohnso/algae.html   (3053 words)

  
 Animal Phyla
Multicellular animals are heterotrophic by ingestion of food into a body cavity (coelom) that is completely lined by the mesoderm.
Multicellular animals have three variations in the site of embryo development and source of nutrition.
Sexual reproduction may involve monoecious species in which members of the population are bisexual (hermaphroditic) with sperm-bearing testicles and egg-bearing ovaries on the same individual.
http://waynesword.palomar.edu/trnov01.htm   (4405 words)

  
 Superoxide signalling required for multicellular development of Dictyostelium -- Bloomfield and Pears 116 (16): 3387 -- ...
the unicellular to multicellular phase of Dictyostelium, suggesting
transition from the single to multicellular phases of Dictyostelium.
eukaryote as it switches to a multicellular phase suggests that
http://jcs.biologists.org/cgi/content/full/116/16/3387   (6669 words)

  
 Investigations with a Multicellular Developmental Model - Fleischer (ResearchIndex)
32 A simulation testbed for the study of multicellular developm..
Biological development is a complicated process involving cells interacting under genetic control.
0.3: A Simulation Testbed for the Study of Multicellular..
http://citeseer.ist.psu.edu/79163.html   (460 words)

  
 Multicellular
Any organism which is composed of many cells is termed multicellular.
http://www.cartage.org.lb/en/themes/Reference/dictionary/cellular/M/Multicellular.html   (11 words)

  
 Dendritic cells for NK/LAK activation: rationale for multicellular immunotherapy in neuroblastoma patients -- ...
Dendritic cells for NK/LAK activation: rationale for multicellular immunotherapy in neuroblastoma patients
Dendritic cells for NK/LAK activation: rationale for multicellular immunotherapy in neuroblastoma patients -- Valteau-Couanet et al.
model to demonstrate the efficacy of such a combined multicellular
http://www.bloodjournal.org/cgi/content/full/100/7/2554   (5949 words)

  
 Kingdom Protista
Most are unicellular, some are colonial, and other are simple multicellular organisms closely related to single protist cells.
The ciliates are primarily free-living protozoans who move by means of numerous cilia, and contain two different types of nuclei: a large macronucleus that controls cell metabolism and development, and many smaller micronuclei that function in sexual reproduction.
When sufficient bacteria (food) are present, cellular slime molds are single amoeboid cells; however, when food becomes scarce, they aggregate into sluglike colonies, which become large reproductive structures.
http://sidwell.edu/us/science/vlb5/Labs/Classification_Lab/Eukarya/Protista   (999 words)

  
 BioMed Central Full text A molecular timescale of eukaryote evolution and the rise of complex multicellular life
The results suggest that oxygen levels in the environment, and the ability of eukaryotes to extract energy from oxygen, as well as produce oxygen, were key factors in the rise of complex multicellular life.
The results support a deep history for complex multicellular eukaryotes, and implicate oxygen as a possible trigger for the rise in complex life.
The pattern and timing of the rise in complex multicellular life during Earth's history has not been established.
http://www.biomedcentral.com/1471-2148/4/2   (4346 words)

  
 Modification of Type IV Pilus-Associated Epithelial Cell Adherence and Multicellular Behavior by the PilU Protein of ...
Modification of Type IV Pilus-Associated Epithelial Cell Adherence and Multicellular Behavior by the PilU Protein of Neisseria gonorrhoeae -- Park et al.
Modification of Type IV Pilus-Associated Epithelial Cell Adherence and Multicellular Behavior by the PilU Protein of Neisseria gonorrhoeae
http://iai.asm.org/cgi/content/abstract/70/7/3891   (507 words)

  
 Emergent patterns of growth controlled by multicellular form and mechanics -- Nelson et al., 10.1073/pnas.0502575102 -- ...
from their multicellular organization, and result in patterns
Emergent patterns of growth controlled by multicellular form and mechanics
Thus, tissue form is not only a consequence but also
http://www.pnas.org/cgi/content/abstract/0502575102v1   (278 words)

  
 NEW EMBO MEMBER'S REVIEW: Crawling into a new era--the Dictyostelium genome project -- Eichinger and Noegel 22 (9): ...
aggregate by chemotaxis to form a multicellular structure that
lies at the border between single-celled and multicellular organisms.
Dictyostelium discoideum is an excellent model system for studying
http://embojournal.npgjournals.com/cgi/content/full/22/9/1941   (3205 words)

  
 Size and Shape in Diatoms
Depending on their mode of construction, colonies may be flexible, or rigid.
Although individual cells are most commonly in the size range of 10 - 200 µm, many planktonic diatoms form multicellular chains which can be several millimeters in length, occasionally exceeding a centimeter.
The silicified cell wall allows them to exhibit a multitude of complex, often highly geometric shapes at both the cellular and colonial levels.
http://thalassa.gso.uri.edu/ESphyto/sizeshap/shape.htm   (413 words)

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