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| | Serotonin - Wikipedia, the free encyclopedia |
 | | The MAOIs prevent the breakdown of monoamine neurotransmitters (including serotonin) and therefore increase concentrations of the neurotransmitter in the brain. | | | As with all neurotransmitters, the actual effects of 5-HT on the human mood and state of mind are very difficult to ascertain. | | | MAOI therapy is associated with many adverse drug reactions and patients are at risk of hypertensive crisis triggered by foods with high tyramine-content and certain drugs. |
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http://en.wikipedia.org/wiki/Serotonin
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| | REHAVI, MOSHE, Ph |
| | Characterization of the vesicular monamine transporter in rat brain. | | | In order to develop a peripheral cellular model for the investigation of the DA transporter in clinical conditions we characterize this uptake site in human platelets. | | | We study the regulation of the dopamine transporter by chronic treatments with antiparkinson and antipsychotic drugs. |
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http://www.tau.ac.il/medicine/Med_school/Physiology/ResearchDir/Rehavi.htm
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| | Postnatal development of the monoamine vesicular transporter in mesencephalic and telencephalic regions of the rat ... |
| | Postnatal development of the monoamine vesicular transporter in mesencephalic and telencephalic regions of the rat brain: a quantitative autoradiographic study with [3H]dihydrotetrabenazine. | | | [3H]Dihydrotetrabenazine [3H]TBZOH, a high affinity ligand of the monoamine vesicular transporter, has been used to study by autoradiography the development of monoaminergic synaptic vesicles from birth to adulthood, in the rat brain. | | | This increase was more pronounced in the olfactory tubercle. |
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http://www.arclab.org/medlineupdates/abstract_2290604.html
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| | Monoamine transporter -- Facts, Info, and Encyclopedia article |
| | DAT, NET and SERT are related to each other and they all consist of a structure of 12 (Click link for more info and facts about transmembrane helices) transmembrane helices. | | | Many drugs, such as (Any of a class of drugs used to treat depression; often have undesirable side effects) antidepressants and (Click link for more info and facts about psychoactive) psychoactives effect the monoamine transporters. | | | The (A monoamine neurotransmitter found in the brain and essential for the normal functioning of the central nervous system; as a drug (trade names Dopastat and Intropin) it is used to treat shock and hypotension) dopamine transporter, (An audiotape recording of sound) DAT. |
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http://www.absoluteastronomy.com/encyclopedia/m/mo/monoamine_transporter.htm
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| | MUSC Neurosciences |
| | Elucidating the monoamine transporter mechanisms that undergo adaptive changes in the animal model of relapse could identify novel molecular targets for pharmacological intervention in addiction. | | | Chronic self-administration of psychostimulats and other drugs of abuse are a major health problem world wide with profound social and financial cost. | | | Thus, the monoamine transporters are the primary high affinity targets for cocaine in the brain and drug-induced changes in transporter kinetics and number will strongly influence the effects of subsequent drug administration. |
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http://neuroscience.musc.edu/research/narc/projects/ramamoorthy_project.html
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| | Untitled Document |
| | My research is focused on enhancing our understanding of the processes by which the dopamine transporter and other biogenic monoamine transporers are regulated and to identify other proteins that are involved in this process. | | | Others and we have found this process and also other biochemical and pharmacological properties of biogenic monoamine transporters seem to vary with the expression system used. | | | Another project of our lab involves the use of DNA micro-arrays to investigate the differential gene expression patterns in the brains of rats treated chronically with inhibitors of biogenic monoamine transporter. |
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http://www.neurobio.pitt.edu/faculty/mortensen.htm
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| | Toward a Rapidly Acting Antidepressant: The Normetanephrine and Extraneuronal Monoamine Transporter (Uptake 2) ... |
| | such as "extraneuronal uptake," "uptake 2," "extraneuronal monoamine | | | Toward a Rapidly Acting Antidepressant: The Normetanephrine and Extraneuronal Monoamine Transporter (Uptake 2) Hypothesis | | | Toward a Rapidly Acting Antidepressant: The Normetanephrine and Extraneuronal Monoamine Transporter (Uptake 2) Hypothesis -- Schildkraut and Mooney 161 (5): 909 -- American Journal of Psychiatry |
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http://ajp.psychiatryonline.org/cgi/content/abstract/161/5/909
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| | The Telegraph - Calcutta : International |
| | Studies on twins showed that those with this gene, a vesicular monoamine transporter that regulates the flow of mood-altering chemicals in the brain, were more likely to develop a spiritual belief. | | | Growing up in a religious environment was said to have little effect on belief. | | | The higher their score, the greater a person’s ability to believe in a greater spiritual force and, Hamer found, the more likely they were to share the gene, VMAT2. |
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http://www.telegraphindia.com/1041115/asp/foreign/story_4005561.asp
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| | cars.ca - Auto Transporters |
| | Even as the ban on the burning of stubble in the fields has come into effect, Agricultural Department officials, who are given the responsibility of checking the practice, are still unaware of the powers under which they... | | | Here are some other items you may be interested in. | | | The personal vehicle maker introduces a new promotion through which it will include Garmin handheld GPS devices on its Human Transporters. |
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http://www.cars.ca/Auto-Transporters/reference/search
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| | VMAT, AChT, NET, Proline, SERT, Tau transporters |
| | , previously termed SVAT (synaptic vesicle amine transporter), is primarily found in monoaminergic cell bodies of the central nervous system and also in stomach but not in adrenals. | | | Several distinct transport activities have been identified for monoamines, acetylcholine, glutamate, GABA and glycine. | | | In contrast to the plasma membrane transporters for dopamine, norepinephrine, and 5-HT which show relative substrate specificity, the monoamine transporter recognizes various monoamine with similar affinity. |
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http://www.4adi.com/flr/vmat.html
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| | Genetic Manipulation of Noradrenergic Neurons -- Carson and Robertson 301 (2): 410 -- Journal of Pharmacology And ... |
| | Knockout animals with impaired monoamine signaling are invaluable tools for the study of catecholamine physiology. | | | Although NET is the predominant transporter in neuronal tissue, a second process termed uptake-2 is responsible for removal | | | C, loss of VMAT function in a noradrenergic neuron would impair the ability of dopamine to be transported into vesicles where it could be converted to norepinephrine by DBH. |
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http://jpet.aspetjournals.org/cgi/content/full/301/2/410
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| | Measurement of secretory vesicle pH reveals intravesicular alkalinization by vesicular monoamine transporter type 2 ... |
| | The two VMATs differ in their ability to transport histamine, and in their sensitivity to certain inhibitors, for example reserpine blocks both, but tetrabenzine is selective for VMAT2 (Peter et al. | | | Possibly, VMAT activity leads to proton extrusion such that the proton pump is unable to maintain internal pH; alternatively re-protonation of accumulated amines transported by VMAT may raise intravesicular pH. | | | Unlike normal G-cells, however, HIT-T15 cells do not express VMATs, which offers the opportunity to experimentally restore the capacity for amine transport; moreover their morphology readily allows detection of secretory vesicles progressing from the Golgi to terminal regions. |
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http://jp.physoc.org/cgi/content/full/531/3/605
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| | RGD Gene Report: Slc18a1 |
| | The Bioinformatics Program, HMGC is a part of the Medical College of Wisconsin. | | | transports biogenic amines; may play a role in neuroendocrine vesicular transport | | | RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH. |
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http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=3693
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| | Scotsman.com News - Features - Do you have the God gene? |
| | Now these mind-bending plants act on brain chemicals called monoamines, the most important of which are serotonin and dopamine. | | | Genes affecting the function and transport of these chemicals were analysed, using material from the 1,001 volunteer candidates. | | | And, to cut a long research story short, after trial and error, one gene showed variations (called polymorphisms) which tied in with the gene-owners’ levels of assessed self-transcendence. |
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http://news.scotsman.com/features.cfm?id=1463022004
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| | ipedia.com: Reuptake Article |
| | Reuptake is the reabsorption of a neurotransmitter by the molecular transporter of a pre-synaptic neuron after it has performed its function of transmitting a neural impulse. |
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http://www.ipedia.com/reuptake.html
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| | Science Musings by Chet Raymo |
| | The gene codes for a protein called a monoamine transporter, one of a family of chemicals that controls crucial signaling in the brain. | | | The gene is rather prosaically named VMAT2, and the relevant variation is as simple as one chemical tread on the DNA spiral staircase -- in the language of the geneticist, a C rather than an A at position 33050 of the human genome. | | | One variation of one gene showed a statistically significant correlation with high scores on the self-transcendence inventory. |
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http://www.sciencemusings.com/2005/06/itch-for-god.html
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| | Search Tuna Report for antidepressants |
| | The selective norepinephrine and dopamine reuptake inhibitor bupropion defines a novel class of antidepressant that has no direct actions on the serotonin system.... | | | Central nervous system drugs act primary as agonists or antagonists of neurotransmitter receptors, inhibitors of regulatory enzymes or blockers of stimulators of neurotransmitter membrane transporters Table 3.1.... | | | The novel antidepressants are either selective and reversible monoamine oxidase inhibitors,., moclobemide, or selective serotonin reuptake inhibitors., citalopram or paroxetine, or serotonin and noradrenaline reuptake inhibitors., venlafaxine.... |
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http://www.searchtuna.com/ftlive2/3495.html
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| | Energy Citations Database (ECD) - Energy and Energy-Related Bibliographic Citations |
| | Availability information may be found in the Availability, Publisher, Research Organization, Resource Relation and/or Author (affiliation information) fields and/or via the "Full-text Availability" link. | | | For a journal article, please see the Resource Relation field. | | | Photoaffinity labeling of the monoamine transporter of bovine chromaffin granules and other monoamine storage vesicles using 7-azido-8-(sup 125 I)iodoketanserin |
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http://www.osti.gov/energycitations/product.biblio.jsp?osti_id=5405146
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| | The Unfolded Protein Response Regulates Glutamate Receptor Export from the Endoplasmic Reticulum -- Shim et al. 15 ... |
| | Duerr, J.S., Frisby, D.L., Gaskin, J., Duke, A., Asermely, K., Huddleston, D., Eiden, L.E., and Rand, J.B. The cat-1 gene of Caenorhabditis elegans encodes a vesicular monoamine transporter required for specific monoamine-dependent behaviors. | | | Interaction with the Unfolded Protein Response Reveals a Role for Stargazin in Biosynthetic AMPA Receptor Transport | | | Ma, D., and Jan, L.Y. ER transport signals and trafficking of potassium channels and receptors. |
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http://www.molbiolcell.org/cgi/content/full/15/11/4818
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| | [No title] |
| | REFERENCE 1 (bases 1 to 1800) AUTHORS Erickson,J.D. and Eiden,L.E. TITLE Functional identification and molecular cloning of a human brain vesicle monoamine transporter JOURNAL J. Neurochem. | | | LOCUS HUMVMAT2 1800 bp mRNA PRI 14-JAN-1995 DEFINITION Human vesicle monoamine transporter (VMAT2) mRNA, complete cds. | | | ACCESSION L23205 VERSION L23205.1 GI:349711 KEYWORDS vesicle monoamine transporter. |
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http://pharmacogenetics.ucsf.edu/public-results/vmat2/l23205.ref
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| | Stimulation of MMP-7 (matrilysin) by Helicobacter pylori in human gastric epithelial cells: role in epithelial cell ... |
| | Hussain, I., Bate, G. W., Henry, J., Djali, P., Dimaline, R., Dockray, G. and Varro, A. Modulation of gastrin processing by vesicular monoamine transporter type 1 (VMAT1) in rat gastrin cells. | | | Hotchin, N. A., Cover, T. and Akhtar, N. Cell vacuolation induced by the VacA cytotoxin of Helicobacter pylori is regulated by the Rac1 GTPase. |
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http://jcs.biologists.org/cgi/content/full/116/14/3017
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| | biology - VMAT2 |
| | VMAT2 with VMAT1 are the two Isoforms of the Vesicular Monoamine Transporter protein. |
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http://www.biologydaily.com/biology/VMAT2
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| | TIP - Publications - 2000 |
| | [00505] Hall S, Sora I, Li X-F, Uhl GR (2000) Nisoxetine and fluoxetine become rewarding in dopamine transporter knockout mice. | | | [00500] Itokawa K, Sora I, Hall FS, Takahashi N, Li X-F, Ookuma A, Shimizu K, Uhl GR (2000) Aging of vesicular monoamine transporter (VMAT2) knockout mice and dopamine transporter (DAT) knockout mice. |
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http://www.prit.go.jp/En/Archives/arch00.html
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