|
| |
| | Psychiatric Times |
 | | I believe this reputation of moclobemide as a weaker antidepressant than others is undeserved and is not supported by either research data or clinical experience. | | | Moclobemide is no more or less effective in depression marked by psychomotor retardation or agitation nor in major depression with atypical features. | | | Although moclobemide has comparable efficacy and tolerability to SSRIs in controlled trials (Bougerol and coworkers; Williams and others), these studies do not assist in deciding the relative advantages or disadvantages of moclobemide over other new-generation antidepressants in a particular patient or clinical situation. |
|
http://www.psychiatrictimes.com/p960623.html
(1897 words)
|
|
| |
| | United States Patent Application: 0020032197 |
| | A method for treating psychogenic pain disorder in a human, which comprises administering to a human in need of treatment for pain disorder a therapeutically effective amount of moclobemide, a moclobemide metabolite, a moclobemide derivative or a moclobemide composition. | | | A method for treating chronic nociceptive pain in a human, which comprises administering to a human in need of treatment for chronic nociceptive pain a therapeutically effective amount of moclobemide, a moclobemide metabolite, a moclobemide derivative or a moclobemide composition. | | | [0157] Moclobemide, a moclobemide metabolite, a moclobemide derivative or a moclobemide composition may also be administered before, along with, or after traditional psychotherapy, in particular cognitive behavioral therapy. |
|
http://appft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&u=/netahtml/PTO/search-adv.html&r=1&f=G&l=50&d=PG01&p=1&S1=20020032197&OS=20020032197&RS=20020032197
(13467 words)
|
|
| |
| | MedlinePlus Drug Information: Moclobemide (Systemic) |
| | Liver disease—Effects of moclobemide may be increased because of slower removal of the medicine from the body; your doctor may need to change your dose | | | Children—Studies on moclobemide have been done only in adult patients, and there is no specific information comparing use of moclobemide in children with use in other age groups. | | | After you stop using this medicine, you must continue to exercise caution for at least 1 to 2 weeks concerning drink and other medicine, since these things may continue to react with moclobemide. |
|
http://www.nlm.nih.gov/medlineplus/druginfo/uspdi/500127.html
(1618 words)
|
|
| |
| | TREATMENTS FOR DEPRESSION |
| | Moclobemide can "interact" with a number of other medicines although it does not necessarily mean the drugs can not be used together, just that you may need to follow your doctors instructions very carefully. | | | You should be careful as it may affect your reaction times or reflexes. | | | By stopping this breakdown, moclobemide helps to bring back the amounts of monoamines to normal. |
|
http://www.nmhct.nhs.uk/pharmacy/depr4.htm
(2299 words)
|
|
| |
| | Order MANERIX @ Rx Care Canada |
| | Because there are no data available on the use of moclobemide in such patients, caution is advised when prescribing moclobemide to these subjects. | | | There is little experience regarding the concomitant use of moclobemide and antipsychotic drugs. | | | Buspirone: To date, there is no experience regarding the co-administration of moclobemide and buspirone. |
|
http://canadadrugs.rxcarecanada.com/MANERIX.asp?prodid=MANERIX
(2815 words)
|
|
| |
| | Moclobemide (PIM 151) |
| | There are no effective methods known to enhance the elimination of moclobemide. | | | Fulton B & Benfield P (1996) Moclobemide An update of its Pharmacological Properties and Therapeutic Use. | | | Treatment of the serotonin syndrome may require aggressive supportive care including diazepam, mechanical ventilation, external cooling and if necessary, curarization. |
|
http://www.inchem.org/documents/pims/pharm/pim151.htm
(3419 words)
|
|
| |
| | Meta-Analysis of the Reversible Inhibitors of Monoamine Oxidase Type A Moclobemide and Brofaromine for the Treatment of ... |
| | Moclobemide Contrasted with Placebo Across inpatient and outpatient settings, 12 studies contrasted MOC with PBO (see Table 4). | | | In contrast to the analyses of MOC, the three studies that contrasted BRO with tranylcypromine failed to yield any evidence of an advantage for the older MAOI (Nolen et al. | | | An initial literature review was conducted using MEDLINE and Psychological Abstracts, targeting the following key words: monoamine oxidase inhibitors, RIMAs, moclobemide, and brofaromine. |
|
http://www.nature.com/cgi-taf/dynapage.taf?file=/npp/journal/v20/n3/full/1395258a.html
(8974 words)
|
|
| |
| | DG DISPATCH - ECNP: Sexual Dysfunction Less Likely In Depressed Patients Taking Moclobemide |
| | Among the women, 68 percent had problems with sexual arousal, 55 percent were unable to achieve orgasm and 68 percent were dissatisfied overall with their sexual functioning. | | | The authors concluded the two treatments were equally effective in relieving depression but sexual dysfunction was more likely to emerge in patients taking SSRIs. | | | Half of the patients received treatment with an SSRI and half with the reversible monoamine oxidase-A inhibitor moclobemide. |
|
http://www.pslgroup.com/dg/132c12.htm
(495 words)
|
|
| |
| | SOFT/TIAFT 98 - Moclobemide Toxicity and Serotonin Reuptake Inhibitors |
| | The author has recognised that adverse interactions of moclobemide occur with SSRI even when SSRIs are used in therapeutic amounts. | | | There are few mentions of any significant toxicity with this drug alone, even in overdose, although interactions of moclobemide with clomipramine and serotonin reuptake inhibitors (SSRI) are known when these drugs are taken to excess. | | | Moclobemide is a reversible inhibitor of monoamine oxidase A and is widely used to treat depression. |
|
http://www.tiaft.org/tiaft98/thu/p/t_p_15.html
(311 words)
|
|
| |
| | An iodinated derivative of moclobemide as potential radioligand for brain MAO-A exploration. |
| | By contrast, in vivo biodistribution in the rat brain showed that [125I]-Ro 11-990 accumulated in a region corresponding to the localization of locus coeruleus known for its high density of MAO-A. | | | In vitro experiments on rat brain homogenates showed that Ro 11-9900 had poor inhibitory activity on MAO-A, as already described for moclobemide. | | | In vivo evaluation of MAO-A would be of great value for the diagnosis and follow-up of therapy of depression. |
|
http://www.pdg.cnb.uam.es/UniPub/iHOP/gp/528632.html
(233 words)
|
|
| |
| | Modification of the cardiovascular effects of ephedrine by the reversible monoamine oxidase A-inhibitor moclobemide. |
| | Irreversible, nonselective monoamine oxidase (MAO) inhibitors have been reported adversely to interact with indirectly acting sympathomimetic amines present in many cough and cold medicines. | | | Moclobemide treatment, however, increased the incidence of adverse events elicited by ephedrine, particularly palpitations and headache. | | | In conclusion, the combined use of moclobemide and high doses of sympathomimetic drugs should be approached with caution. |
|
http://www.pdg.cnb.uam.es/UniPub/iHOP/gp/940544.html
(255 words)
|
|
| |
| | The Psyche-Publication of WMMHC-UMKC |
| | There is no evidence of an increased risk of suicidal behavior in users of moclobemide. | | | Moclobemide is a reversible and selective inhibitor of monoamine oxidase subtype A (RIMA) with a wide spectrum of antidepressant activity. | | | Close compound monitoring through development and after launch has confirmed the safety of moclobemide in therapeutic doses and in overdose. |
|
http://cctr.umkc.edu/user/sajaffri/psy/psjan.htm
(782 words)
|
|
| |
| | Moclobemide - Patient UK |
| | A persistent throbbing headache is a sign of an interaction with a food. | | | Along with their useful effects all medicines can cause unwanted side effects, which usually improve as your body adjusts to the new medicine. | | | The dose that you are taking may need to be changed. |
|
http://www.patient.co.uk/showdoc/30002687
(832 words)
|
|
| |
| | Moclobemide - buy Moclobemide online - order Moclobemide without prescription |
| | If you're looking for a better way to order Moclobemide or other medicine, AllNetMeds.com is right for you! | | | Answer- You can obtain quality prescription medications at a great savings through our affiliated partners, leaders in discount drugs online. | | | AllNetMeds.com makes ordering prescription drugs like Moclobemide faster, easier, and safer than ever before. |
|
http://www.allnetmeds.com/o/n_dr/Moclobemide.shtml
(290 words)
|
|
| |
| | Moclobemide - Wikipedia, the free encyclopedia |
| | Social Phobia, as part of an integrated concept involving also psychotherapy | | | Combination treatment with Pethidine (Interaction may be fatal) | | | A single dose of 300mg Moclobemide inhibits 80% of MAO-A and 30% of MAO-B. Therefore Moclobemide blocks the decomposition of norepinephrine, serotonin, and to a leeser extend of dopamine, and increases their concentrations in the body and especially in the brain. |
|
http://www.wikipedia.org/wiki/Moclobemide
(820 words)
|
|
| |
| | Onset of improvement under Fluoxetine and Moclobemide |
| | Meta- analysis of imipramine and moclobemide vesus placebo. | | | Of this sample, 437 patients received the monoamine oxidase-A inhibitor moclobemide, and 440 patients the selective serotonin re-uptake inhibitor fluoxetine. | | | Among responders to fluoxetine and moclobemide, the distributions of time spans to onset of improvement turned out to be virtually independent of treatment, as indicated by the cumulative percentage rates of improvers, regarded as a function of time (Table 1). |
|
http://www.bli.unizh.ch/BLI/Projects/psychopharmacology/K276.html
(804 words)
|
|
| |
| | LETTER TO THE EDITOR: A Fatal Case of Moclobemide–Citalopram Intoxication |
| | The authors describe the postmortem determination of moclobemide and citalopram using a newly developed analytic technique. | | | Although the untreated syndrome may be life-threatening, this is not as common as the authors suggest. | | | The intrinsic toxicity of citalopram and moclobemide, other than the combination producing serotonin syndrome, is not discussed. |
|
http://www.jatox.com/abstracts/2001/nov-dec/716-letter.htm
(890 words)
|
|
| |
| | MOCLOBEMIDE |
| | I would like information about this new drug MOCLOBEMIDE | | | > I would like information about this new drug > MOCLOBEMIDE | | | If you'd like to include a link to another page with your message, |
|
http://www.rxlist.com/rxboard/general.pl?read=879
(117 words)
|
|
| |
| | Synthesis of Moclobemide |
| | Never use moclobemide with amphetamines, phenethylamines or the like, as severe blood pressure rush, heart attacks and even death may be the result! | | | I suffered severe depression, and doctors refused to prescribe moclobemide to me at first, so I looked up the patent and made me some. | | | Moclobemide is totally legal here, and not controlled. |
|
http://www.erowid.org/archive/rhodium/chemistry/moclobemide.html
(558 words)
|
|
| |
| | MOCLOBEMIDE (MANERIX) |
| | Just get in touch with your doctor if any of the following apply to you:- | | | Below are some conditions where moclobemide should not normally be used. | | | Moclobemide belongs to a group of medicines called the monoamine oxidase inhibitors (or MAOIs). |
|
http://www.nmhct.nhs.uk/pharmacy/pilmocl.htm
(785 words)
|
|
| |
| | IngentaConnect Moclobemide poisoning: toxicokinetics and occurrence of serotonin... |
| | There was no evidence of a dose-dependent increase in half-life. | | | Of 106 included patients, 33 ingested moclobemide alone, 21 ingested moclobemide with another serotonergic agent (in some cases in therapeutic doses) and 52 ingested moclobemide with a nonserotonergic agent. | | | In five patients serial moclobemide concentrations were measured. |
|
http://api.ingentaconnect.com/content/bsc/bjcp/2003/00000056/00000004/art00014
(462 words)
|
|
| |
| | Reversible and selective monoamine oxidase inhibitors |
| | Selective inhibitors of MAO have found a secure place in therapy of depression (inh. | | | of MAO-A, esp. Moclobemide) and Parkinson's disease (inh. | | | Discussed is possible use of selective MAO-inhibitors for achieving an increase in cognitive function and protections of neurone cells from biochemical lesions. |
|
http://www.biopsychiatry.com/rimah.html
(235 words)
|
|
| |
| | IngentaConnect Death following ingestion of MDMA (ecstasy) and moclobemide |
| | As none of the victims had been prescribed moclobemide it seems that each had taken the drug to enhance the effects of MDMA, with fatal consequences. | | | Four deaths following the ingestion of moclobemide and MDMA (‘ecstasy’) are described. | | | Death following ingestion of MDMA (ecstasy) and moclobemide |
|
http://www.ingentaconnect.com/content/bsc/add/2003/00000098/00000003/art00015
(217 words)
|
|
| |
| | ratio-Moclobemide |
| | For additional information about this medication, please contact your doctor or pharmacist. | | | Depression is believed to be caused by imbalances in certain brain chemicals. | | | Moclobemide should not be used by anyone who: |
|
http://www.medbroadcast.com/drug_info_details.asp?brand_name_id=454&dowhat=accept_disclaimer
(264 words)
|
|
| |
| | Moclobemide vs. placebo in the treatment of depression |
| | Moclobemide and sertraline in the treatment of depression | | | Moclobemide was well or very well tolerated by 85% of patients and placebo by 100%. | | | Moclobemide versus placebo in the treatment of depression: a multicentre study in Belgium. |
|
http://www.moclobemide.info/moclobemide/moclobemide-10.htm
(167 words)
|
|
| |
| | Depression and Dysthymia : moclobemide ( Manerix, Aurorix ) |
| | moclobemide, sertraline and desipramine--may permit the long-term clinical management of this spectrum of dysthymic and related conditions. | | | Pharmacotherapy of dysthymic and chronic depressive disorders: overview with focus on moclobemide | | | Open studies conducted around 1980 demonstrated efficacious results with tricyclics, classical MAOIs and lithium in 45% of cases. |
|
http://biopsychiatry.com/mocdys.htm
(183 words)
|
|
| |
| | MOCLOBEMIDE - ORAL TABLET side effects, medical uses, and drug interactions. |
| | MOCLOBEMIDE - ORAL TABLET side effects, medical uses, and drug interactions. | | | Before using this medication, tell your doctor of all the medicines you use (both prescription and nonprescription), especially of: levodopa, insulin and oral diabetes drugs, other MAO inhibitors (e.g., furazolidone, linezolid, phenelzine, tranylcypromine), sedatives, sleeping pills, blood pressure drugs. | | | If you are currently using any of these medications, tell your doctor or pharmacist before starting moclobemide. |
|
http://www.medicinenet.com/moclobemide-oral_tablet/page2.htm
(477 words)
|
|
| |
| | [No title] |
| | Hence, some doctors give moclobemide without requiring patients to follow a tyramine-free diet, although patients on moclobemide are somewhat more susceptible to tyramine's blood pressure increasing effects than are people who are not taking a MAOI. | | | I do not have extensive experience with moclobemide, but as I understand it, studies using less than 900 mg/d have not shown efficacy, so before abandoning this agent, I would increase the dose to at least 900 mg/d. | | | Second, I am not sure whether withdrawal symptoms have occurred with moclobemide, but since many antidepressants are associated uncomfortable physical symptoms if they are suddenly stopped, I would taper the dose once it is determined to be ineffective. |
|
http://chaos.cpmc.columbia.edu/nyspi/askthedr/for_Pt/displayanswer1-depr.asp?Departments=depr&Controlnumber=1370
(342 words)
|
|
| |
| | Moclobemide ( Manerx , Aurorix ) and social phobia |
| | All previous non-responders to moclobemide and mostly alcohol abusers (36.9%), had moderate or severe social phobia and were off all treatment (13.3%), on psychotherapy (15.9%) or on another psychotropic drug (8.8%). | | | Symptoms recurred in a substantial number of the patients at the end of the study when the dose was reduced and then discontinued. | | | Post-study follow up at 6-24 months after study completion found that 63.2% of patients were almost asymptomatic or had only mild symptoms, 15.8% were off all treatment, 28.1% were back on moclobemide, 10.6% were taking another psychotropic drug and 8.8% were in psychotherapy. |
|
http://biopsychiatry.com/moclobsocphob.htm
(325 words)
|
|
| |
| | new depression drugs, picamilon, reboxetine, tianeptine, moclobemide, galantamine |
| | new depression drugs, picamilon, reboxetine, tianeptine, moclobemide, galantamine | | | The above article is copyrighted and may not be copied without the written permission of International Antiaging Systems, Les Autelets Suite A, Sark GY9 0SF, Channel Islands, UK. |
|
http://www.cancer-help.com/smartcom/depression-new-drugs.htm
(1572 words)
|
|
| |
| | Moclobemide versus clomipramine in nonmelancholic, nonpsychotic major depression |
| | According to the RDS as well as the global impression of both patient and physician, a somewhat earlier onset of antidepressant action was evident in the moclobemide group. | | | Moclobemide versus clomipramine in nonmelancholic, nonpsychotic major depression | | | No statistically significant difference between the treatments was found on the number of responders, at 6 weeks and 3 months, to the Hamilton Depression Rating Scale (HDRS), which was the main criterion for efficacy. |
|
http://www.elsevier.com/homepage/sab/ratingscales/data/chapters/Abstracts/xvi-1-2.htm
(307 words)
|
|
| |
| | Moclobemide - Moclobemide Side Effects - Moclobemide Information - Canada Pharmacy - Canada Drugs |
| | Moclobemide - Moclobemide Side Effects - Moclobemide Information - Canada Pharmacy - Canada Drugs | | | Moclobemide - Moclobemide Side Effects - Moclobemide Information | | | Nonmedicinal ingredients: carnauba wax, colloidal silicon dioxide, croscarmellose sodium, dextrates, hydroxypropyl methylcellulose, magnesium stearate, polydextrose, polyethylene glycol 3350 (carbowax), titanium dioxide and yellow ferric oxide. |
|
http://www.rxcarecanada.com/Moclobemide.asp
(279 words)
|
|
| |
| | 21-6/Peter P. Singer.../An Uncommon Fatality Due to Moclobemide... |
| | Deaths attributed primarily to these drugs are extremely rare because both are considerably less toxic than older monoamine oxidase and tricyclic antidepressant drugs. | | | Paramedics found his jaw unusually stiff and were unable to open his mouth in order to intubate him. | | | The cause of death was attributed to the combined toxicity of moclobemide and paroxetine. |
|
http://www.jatox.com/abstracts/1997/october/sin2abs.htm
(220 words)
|
|
| |
| | MANERIX, Buy MANERIX (MOCLOBEMIDE) (AURORIX) Online |
| | Manerix is also not advisable if you have had any previous allergic reactions to other monoamine oxidase inhibitors or to moclobemide. | | | Click to learn how to SAVE 90% on Surgery and Healthcare Costs | | | In some countries MANERIX may also be known as: Moclobemide, Aurorix, Moclamine |
|
http://www.drugdelivery.ca/s3269-s-MANERIX.aspx
(641 words)
|
|
| |
| | Lycaeum > Leda > 2C-B + Moclobemide + Ketamine |
| | there was a 4x potentiation and a definite elongation of the experience using moclobemide. | | | I did try to measure my blood pressure just before injecting the K but I couldn't read the dial so I gave up... | | | Lycaeum > Leda > Trip Reports > 2C-B + Moclobemide + Ketamine |
|
http://leda.lycaeum.org/?ID=5267
(255 words)
|
|
| |
| | Re: What about Moclobemide - an MAOI Type A? |
| | Re: What about Moclobemide - an MAOI Type A? Posted by Judy on May 11, 1999, at 18:11:50 | | | I was excited when I read about Moclobemide but had my bubble burst when my doctor wouldn't allow it because it's not approved in the US by the FDA. | | | Re: What about Moclobemide - an MAOI Type A? Thread |
|
http://www.dr-bob.org/babble/19991001/msgs/5959.html
(188 words)
|
|
| |
| | Klonopin & Moclobemide |
| | I suffer from a Bipolar Spectrum Disorder + Social Phobia, among other things. | | | as opposed to moclobemide, which if you do indeed have a bipolar variant runs the risk of making things worse -- especially as Geodon has not really proven it's | | | I'm currently taking Geodon and we will soon be adding moclobemide for SP, but I'm also interested in Klonopin. |
|
http://www.bipolarworld.net/Phelps/ph_2002/ph800.htm
(204 words)
|
|
|
