|
| |
| | Physicians, researchers & families battle devastating mitochondrial disease |
 | | Naviaux believes that findings in mitochondrial medicine may be "no less significant than the formulation of the germ theory by Louis Pasteur and Robert Koch 100 years ago. | | | Noting that the area of mitochondrial disease research currently is not well funded, Haas hopes that will soon change. | | | Richard Haas, M.B., co-director of UCSD's Mitochondrial and Metabolic Disease Center and conference co-director, says the Mitochondrial 2001 program brings together professionals from a wide variety of medical disciplines. |
|
http://www.eurekalert.org/pub_releases/2001-02/UNKN-Prfb-2502101.php
(1408 words)
|
|
| |
| | NASH: a mitochondrial disease |
| | Mitochondrial function is insufficient in the skeletal muscle of obese and/or (pre)diabetic subjects | | | The purpose of this review is to discuss the evidence, mechanisms and implications of mitochondrial dysfunction at the successive steps leading to NASH, as already partially reviewed elsewhere [3-8]. | | | Due to high matrix osmotic pressure, the opening of this pore causes an influx of water into the mitochondrial matrix. |
|
http://www.natap.org/2005/HIV/060705_05.htm
(5259 words)
|
|
| |
| | Mitochondrial Diseases |
| | A special tract will be offered for newcomers to learn the basics of mitochondrial disease before the detailed medical sessions. | | | If this process is repeated throughout the body, whole systems begin to fail, and the life of the person in whom this is happening is severely compromised. | | | Mitochondria are responsible for creating more than 90% of the energy needed by the body to sustain life and support growth. |
|
http://www.tsbvi.edu/Outreach/seehear/spring02/mitochondrial.htm
(1025 words)
|
|
| |
| | Mitochondrial Disease |
| | Mitochondrial medicine is a new and rapidly developing medical subspecialty. | | | More invasive tests, such as a skin or muscle biopsy, might be performed as needed and recommended by your doctor. | | | For parents considering having other children, genetic counseling is available. |
|
http://clevelandclinic.org/health/health-info/docs/1600/1678.asp?index=6957
(1285 words)
|
|
| |
| | Mitochondrial Disease : A Pulmonary and Critical-Care Medicine Perspective -- Clay et al. 120 (2): 634 -- Chest |
| | Mitochondrial Disease : A Pulmonary and Critical-Care Medicine Perspective -- Clay et al. | | | Cervera, R, Bruix, J, Bayes, A, et al (1988) Chronic intestinal pseudoobstruction and ophthalmoplegia in a patient with mitochondrial myopathy. | | | Sengers, RC, Fischer, JC, Trijbels, JM, et al (1983) A mitochondrial myopathy with a defective respiratory chain and carnitine deficiency. |
|
http://www.chestjournal.org/cgi/content/full/120/2/634
(5831 words)
|
|
| |
| | Mitochondrial Disease & Disorders in children |
| | The vast majority of patients with mitochondrial cytopathies have an uneventful surgery and anesthesia. | | | Besides information on the diseases, they have tons of practical information, including little "help hints" for living with neuromuscular disease. | | | During the first three years of our effort's to find out what was "wrong" with our most affected son, Tim, we were met with constant frustration. |
|
http://www.kathleensworld.com/mitochon.html
(4655 words)
|
|
| |
| | United Mitochondrial Disease Foundation - Medical Article List by Subject |
| | Malcic ; I ; 1795 ; Mitochondrial cardiomyopathy and scapuloperoneal spinal muscular atrophy in a child. | | | Belardinelli ; R ; 3189* ; Exercise training improves left ventricular diastolic filling in patients with dilated cardiomyopathy. | | | We welcome any suggested additions to our list. |
|
http://biochemgen.ucsd.edu/umdf/mito-cardio.htm
(3261 words)
|
|
| |
| | Epilepsy and mitochondrial disease : Epilepsy.com |
| | Other common features are hearing loss, peripheral nerve disease, short stature, exercise intolerance, and impaired vision from damage to the optic nerve. | | | More patients with mitochondrial disease have seizures that are intractable (difficult to control with medication) than patients with epilepsy not associated with another disorder. | | | Generalized discharges are uncommon in patients with mitochondrial disease. |
|
http://www.epilepsy.com/epilepsy/epilespy_mitochondrial_disease.html
(1805 words)
|
|
| |
| | Mitochondrial Disease |
| | All medical information needs to be carefully reviewed with your health care provider. | | | DISCLAIMER: NOAH is an information guide only and cannot answer personal health-related or research questions. | | | NOAH > Genetic Diseases > Specific Conditions > Mitochondrial Disease |
|
http://www.noah-health.org/en/genetic/conditions/mitochondrial
(138 words)
|
|
| |
| | Mitochondrial Disorders |
| | Most sensitive and specific stain for mitochondrial proliferation in muscle fibers | | | COX - fibers: More common in patients with clinical myopathy | | | Ultrastructure may be only evidence of mitochondrial pathology in 6% |
|
http://www.neuro.wustl.edu/neuromuscular/mitosyn.html
(3231 words)
|
|
| |
| | Eric A. Schon, PhD |
| | We are using cybrid technology not only to study genotype phenotype relationships, but also to ask basic questions about mitochondrial biogenesis (e.g. | | | Apparent mtDNA heteroplasmy in Alzheimer's Disease patients and in normals due to PCR amplification of nucleus-embedded mtDNA pseudogenes. | | | A mitochondrial tRNA anticodon swap associated with a muscle disease. |
|
http://cpmcnet.columbia.edu/dept/genetics/faculties/Schon.html
(1349 words)
|
|
| |
| | Mitochondrial Disease - UPCMedicalDirectory |
| | How We Discovered Mitochondrial Disease in our Family. | | | MDA / Quest 6-5 / Mitochondrial Disease in Perspective - Symptoms, | | | The history of mitochondrial disease goes back to the early 1960s, however, when Lars Ernster and Rolf Luft in Stockholm described a patient who ate... |
|
http://www.upcmd.com/?First=Mitochondrial+Disease
(228 words)
|
|
| |
| | United Mitochondrial Disease Foundation |
| | The LEAP Award (Living, Encouraging, Achieving and Persisting) is presented to an individual aged 14 years or older with confirmed or suspected mitochondrial disease and demonstrates a positive attitude and inspires others through their actions. | | | "To promote research and education for the diagnosis, treatment and cure of mitochondrial disorders and to provide support to affected individuals and families." | | | Since 1996, the United Mitochondrial Disease Foundation has funded just under $3,000,000 in research toward a cure and has helped thousands of families through the family support network. |
|
http://www.umdf.org
(319 words)
|
|
| |
| | Mitochondrial Disease: Searching for Answers |
| | Beyond the support and friendships forged during that brief weekend, it was a wonderful opportunity for education in this rapidly changing field. | | | Organs such as the brain, muscles, heart, kidneys, and eyes, which require a lot of energy, will often be the most affected by mitochondrial disorders. | | | For instance, someone with a high number of abnormal mitochondria in the optic nerve may have blindness (Leber’s Hereditary Optic Neuropathy), in the brain may have seizures (Mitochondrial Encephalomyopathy), or in the heart may have heart disease (cardiomyopathy). |
|
http://www.tsbvi.edu/Outreach/seehear/archive/mito.htm
(541 words)
|
|
| |
| | Mitochondrial Disease |
| | Research Activities and Therapeutic Trials Our staff and personnel Archives of our newsletters will be maintained here. | | | Chronic lactic acidosis is a common symptom of mitochondrial disease.. | | | However, even though mitochondrial disease varies greatly in presentation from person to person, several major categories of the disease have been defined, based on the most common symptoms and the... |
|
http://www.jrzb.com.cn/mitochondrialdisease-33101.htm
(236 words)
|
|
| |
| | possible new treatment for mitochondrial disease? - BrainTalk Communities |
| | In his keynote address he mentioned a supplement called Magnesium Orotate which, based on his research, he believes will be very helpful to a lot of mitochondrial patients. | | | I am keeping a record of the results so we can get an idea which kinds of mitochondrial disease it works for and what symptoms it relieves. | | | Like all treatments for mitochondrial disease, what helps one might not help another, but it is easy and inexpensive to try, and appears to be very safe. |
|
http://brain.hastypastry.net/forums/showthread.php?t=68922
(649 words)
|
|
| |
| | Tufts Neurology: Mitochondrial disease |
| | MITOCHONDRIAL DISORDERS - Washington University School of Medicine, St. Louis, MO Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke like episodes: a distinctive clinical syndrome. | | | Mitochondria have replaced most other structures in 1/2 of the fiber on righ (Gomori trichrome stain)- Washington University School of Medicine, St. Louis, MO National Institutes of Health, Bethesda, Maryland 20892 | | | Please send your webpages comments or questions to: Paulo Andre, MD |
|
http://tuftsneurology.org/webres/mito.htm
(120 words)
|
|
| |
| | Mitochondrial disease - Wikipedia, the free encyclopedia |
| | The subclass of these diseases that have neuromuscular disease symptoms are often referred to as a mitochondrial myopathy. | | | Mitochondrial diseases comprise those disorders that in one way or another affect the function of the mitochondria and/or are due to mitochondrial DNA. | | | As a general rule, mitochondrial diseases are worst when the defective mitochondria are present in the muscles or nerves, because these are the most energy-hungry cells of the body. |
|
http://en.wikipedia.org/wiki/Mitochondrial_disease
(678 words)
|
|
| |
| | روابط انجليزية |
| | MITOCHONDRIAL and METABOLIC DISORDERS- a primary care physician’s guide | | | Welcome to the Center for Inherited Disease Research | | | Lysosomal Storage Diseases A Family Sourcebook Reference Chart |
|
http://www.werathah.com/learning/english.htm
(470 words)
|
|
| |
| | Tishcon's Recommended Links Page -- tishcon.com |
| | AHRQ - Agency for Healthcare Research and Quality | | | Functional Foods: Their Role in Disease Prevention and Health Promotion | | | CDER - Center for Drug Evaluation and Research |
|
http://www.tishcon.com/links.html
(399 words)
|
|
| |
| | Mitochondrial DNA and Disease |
| | Deletions of muscle mitochondrial DNA in patients with mitochondrial myopathies. | | | Depletion of muscle mitochondrial DNA in AIDS patients with zidovudine-induced myopathy. | | | Mitochondrial myopathies: clinical and biochemical features of 30 patients with major deletions of muscle mitochondrial DNA. |
|
http://www.physics.helsinki.fi/bllmolbi/suomalainen_annmed.html
(6655 words)
|
|
| |
| | Mitochondrial Disease |
| | Mitochondrial disease is very difficult to diagnose because there is no defining symptom to the illness. | | | The symptoms of mitochondrial disease vary with the severity of the disease and the location of the disease. | | | Mitochondrial disease may affect the mitochondria in numerous ways: one of those ways being the many chemical reactions that take place. |
|
http://www.mindbodyfocused.com/body/mitochondrial-disease.php
(529 words)
|
|
| |
| | Recognizing mitochondrial disease : Epilepsy.com |
| | Many patients with a mitochondrial cytopathy have muscle involvement. | | | The degree of mitochondrial dysfunction, the organs involved, and environmental conditions (for instance, whether the person has another chronic illness) will determine the severity of the disease. | | | Mitochondrial disease or cytopathy (from cyto-, cell, and -pathy, disease) is not uncommon. |
|
http://www.epilepsy.com/epilepsy/recognizing_mitochondrial_disease.html
(1099 words)
|
|
| |
| | About UMDF |
| | Our mission is to promote research and education for the diagnosis, treatment and cure of mitochondrial disorders and to provide support to affected individuals and families. | | | The United Mitochondrial Disease Foundation is redefining hope for families affected by mitochondrial diseases – hereditary disorders, now considered as common as childhood cancers, that affect the cell's ability to produce life-sustaining energy. | | | "To promote research and education for the diagnosis, treatment and cure of mitochondrial disorders and to provide support to affected individuals and families." |
|
http://www.umdf.org/about_umdf/generalinfo.aspx
(151 words)
|
|
| |
| | Mitochondrial Myopathy (MITO) MDA |
| | Mitochondrial Disorders — Prevention of Toxicity With Dichloroacetate Treatment of Lactic Acidemia [new 06/03] | | | MDA Researchers Discover Possible Key to EffectiXve Stem Cell Therapy in Muscle Diseases [9/15/00] | | | Mitochondrial Disease in Perspective: Symptoms, Diagnosis and Hope for The Future 10/99 |
|
http://www.mdausa.org/disease/mito.html
(506 words)
|
|
| |
| | Disease Parkinson White Wolff |
| | Wolff-Parkinson-White (WPW) syndrome is a disturbance in the electrical pathway of the heart that may cause... | | | Congenital heart disease may contribute to this and other arrhythmias... | | | treat a health problem or disease without consulting with a qualified healthcare... |
|
http://www.glycoaction.com/disease/disease-parkinson-white-wolff.htm
(471 words)
|
|
| |
| | United Mitochondrial Disease Foundation - Links |
| | Barnett Center for the Investigation and Treatment of Mitochondrial Disorders | | | The other DNA: research on mitochondrial diseases - by Drs. | | | MMRD - Mitochondrial Myopathies and Related Disorders usenet news group |
|
http://biochemgen.ucsd.edu/umdf/Links.htm
(1063 words)
|
|
| |
| | Technorati Tag: mitochondrial disease |
| | Information on Diseases Search the Web for doctor-reviewed articles about diseases and other consumer health issues. | | | Reasons include mitochondrial disease, cardiomyopathy, neurodegenerative diseases, (like Parkinson's). | | | CoQ10 Deficiency Mitochondrial Disease Learn how to get a lab test for CoQ10 deficiency. |
|
http://technorati.com/tag/mitochondrial+disease
(382 words)
|
|
| |
| | Mitochondrial disease definition - Medical Dictionary definitions of popular medical terms |
| | Mitochondrial disease: Mutations (changes) in the mitochondrial chromosome are responsible for a number of disorders including, for example: | | | Mitochondrial disease definition - Medical Dictionary definitions of popular medical terms | | | MedicineNet Home > MedTerms medical dictionary A-Z List > Mitochondrial disease |
|
http://www.medterms.com/script/main/art.asp?articlekey=4400
(288 words)
|
|
| |
| | Medcyclopaedia - Mitochondrial disease |
| | a group of conditions responsible for various types of neurodegenerative disorders, together with peroxisomal disorder and lysosomal disease. | | | Mitochondria are DNA-containing organelles, located in the cytoplasm of the cell; their main role is synthesis of adenosine triphosphate, ATP, the main source of energy for the cell. | | | Deficiency of these enzymes cause various types of diseases with multiorgan involvement, including the white or grey matter of the brain, or both. |
|
http://www.medcyclopaedia.com/library/topics/volume_vi_1/m/MITOCHONDRIAL_DISEASE.aspx
(139 words)
|
|
| |
| | Chest: Mitochondrial Disease.@ HighBeam Research |
| | Mitochondrial diseases are a heterogeneous group of disorders in which it has been suggested that genetic defects in oxidative phosphorylation lead to specific alterations in exercise performance and lactate metabolism during exercise. | | | To investigate this possibility, we evaluated pulmonary function tests, incremental exercise testing, and serial blood lactate levels in a group of subjects with mitochondrial disease (M) and compared them with a group of patients with nonmitochondrial (N) myopathies and healthy... | | | This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. |
|
http://www.highbeam.com/library/doc0.asp?DOCID=1G1:54099441&refid=holomed_1
(192 words)
|
|
| |
| | NEJM -- Mitochondrial DNA and Disease |
| | in many specialties see patients with mitochondrial diseases. | | | CHINNERY, P. Clinical features, investigation, and management of patients with defects of mitochondrial DNA. | | | and progression of disease, many mitochondrial disorders share |
|
http://content.nejm.org/cgi/content/short/333/10/638
(946 words)
|
|
| |
| | The Children's Mitochondrial Disease Network |
| | Mitochondrial defects have also been linked to Alzheimer's, Parkinson's, Diabetes, Autism, and the aging process? | | | The Information and hyperlinks contained with the EMDN Web Site are for informational and educational purposes only, EMDN has no control over the information that the hyperlinks contain. | | | Registered working name of the European Mitochondrial Disease Network |
|
http://www.emdn-mitonet.co.uk
(93 words)
|
|
| |
| | Possible mitochondrial disease |
| | Testing for Friedrich's ataxia, spinocerebellar atrophy types 1,2, Machado-Joseph disease, mitochondrial disorders, and other testable rare inherited progressive ataxias are sent out to national reference labs like Athena and are rarely performed at individual institutions. | | | We do not perform any of them directly at the Cleveland Clinic to the best of my knowledge. |
|
http://www.medhelp.org/perl6/neuro/archive/4468.html
(366 words)
|
|
| |
| | Mitochondrial Pathology |
| | SDH is the most sensitive stain for detecting mitochondrial proliferation. | | | Increased SDH staining in muscle fibers with mitochondrial proliferation | | | Muscle fibers with excessive SDH staining (left): COX is present in all fibers (right) |
|
http://www.neuro.wustl.edu/neuromuscular/pathol/mitochondrial.htm
(155 words)
|
|
| |
| | Mitochondrial Disease Support Group Online |
| | Do you want to learn more about a disease you can't even pronounce? | | | We want to add everyone with any level of interest to our mailing list so that we can keep them informed of our speakers, events, and local opportunities. |
|
http://www.mitosupport.org
(250 words)
|
|
|
