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Topic: Midazolam



  
 Midazolam - Wikipedia, the free encyclopedia
The antidote for an overdose of midazolam (or any other benzodiazepine) is flumazenil (Anexate®).
Therefore, midazolam will interact with other 3A4 substrates and inhibitors.
Status Epilepticus: Clinical Analysis of a Treatment Protocol Based on Midazolam and Phenytoin, Brevoord, J. et al., Journal of Child Neurology 2005;20(6):476-48
http://en.wikipedia.org/wiki/Midazolam   (631 words)

  
 MedlinePlus Drug Information: Midazolam (Systemic)
Midazolam (MID-ay-zoe-lam) is used to produce sleepiness or drowsiness and to relieve anxiety before surgery or certain procedures.
Midazolam is given only by or under the immediate supervision of a doctor trained to use this medicine.
If you will be receiving midazolam during surgery, your doctor or anesthesiologist will give you the medicine and closely follow your progress.
http://www.nlm.nih.gov/medlineplus/druginfo/uspdi/202372.html   (998 words)

  
 Intravenous midazolam infusion for sedation of infants in the neonatal intensive care unit
With regards to the safety of midazolam use in infants, further studies on the short and long term adverse effects associated with the use of midazolam are needed.
With the development of such scales, further research on the effectiveness of sedatives such as midazolam infusion on term and preterm infants may be performed.
Two infants from the midazolam group and two from the placebo group were withdrawn from the study within 72 hours due to rapid clinical improvement.
http://www.nichd.nih.gov/cochrane/ng2/ng.htm   (6716 words)

  
 Midazolam
Midazolam is a drug that causes relaxation and sleep.
Your condition will be closely monitored by a health care professional while you receive midazolam
Your condition will be closely monitored while you receive midazolam
http://www.stjohn.org/HealthInfoLib/swArticle.aspx?26,403   (1128 words)

  
 CHEST: Midazolam as intravenous sedative for electrocardioversion
Transient hypertension in patients given midazolam could be related to enhanced adrenergic activity in response to pain of local injection.
Additionally, the incidence of nonamnesia with diazepam in cardioversion has been reported to be up to 37 percent.
In contrast, the same patient had a vivid recollection of pain and discomfort associated with at least two cardioversions carried out under diazepam sedation.
http://www.findarticles.com/p/articles/mi_m0984/is_n5_v95/ai_7832707   (1311 words)

  
 In Vitro, Pharmacokinetic, and Pharmacodynamic Interactions of Ketoconazole and Midazolam in the Rat -- Kotegawa et al. ...
Interactions of midazolam and ketoconazole were studied in vivo and in vitro in rats.
The midazolam concentration-effect relationship was well described by eq.
Thummel KE and Wilkinson GR (1998) In vitro and in vivo drug interactions involving human CYP3A.
http://jpet.aspetjournals.org/cgi/content/full/302/3/1228   (4973 words)

  
 Oral Midazolam Premedication for Pediatric Patients
Children who are premedicated with midazolam prior to surgery have fewer negative behavioral changes in the immediate postoperative period.
Children who will not accept a gentle inhalational induction are more likely to swallow a Versed elixir (midazolam mixed with your vehicle of choice) than they are to meekly allow you to insert a cold solution up their anus.
Last June-July, during the PAC discussion of postop behavior in children premedicated w/ oral midazolam, Zeev Kain mentioned that the prelim results of a RCT would be presented at the ASA meeting in San Diego.
http://gasnet.med.yale.edu/esia/1998/june/threads.html   (4852 words)

  
 Midazolam: An Effective Antiemetic After Cardiac Surgery--A Clinical Trial -- Sanjay and Tauro 99 (2): 339 -- ...
Midazolam: An Effective Antiemetic After Cardiac Surgery--A Clinical Trial -- Sanjay and Tauro 99 (2): 339 -- Anesthesia & Analgesia
Midazolam: An Effective Antiemetic After Cardiac Surgery—A Clinical Trial
midazolam group, compared with a 21% incidence of PONV in the
http://www.anesthesia-analgesia.org/cgi/content/abstract/99/2/339   (239 words)

  
 Cytochrome P4502B6 and 2C9 do not metabolize midazolam: kinetic analysis and inhibition study with monoclonal ...
Midazolam is an intravenous anaesthetic used widely in clinical
to the metabolism of midazolam by kinetic analysis of human
Each plot is the mean of three experiments.
http://bja.oxfordjournals.org/cgi/content/full/86/4/540   (2543 words)

  
 Buprenorphine and Midazolam Act in Combination to Depress Respiration in Rats -- Gueye et al. 65 (1): 107 -- ...
Morel, D. R., Forster, A., Bachmann, M., and Suter, P. Effect of intravenous midazolam on breathing pattern and chest wall mechanics in humans.
Buprenorphine and Midazolam Act in Combination to Depress Respiration in Rats -- Gueye et al.
Buprenorphine and Midazolam Act in Combination to Depress Respiration in Rats
http://toxsci.oxfordjournals.org/cgi/content/full/65/1/107   (4813 words)

  
 A comparison of intramuscular ketamine with high dose intramuscular midazolam with and without intranasal flumazenil in ...
midazolam or he was simply sleeping naturally as it was late
Weinbroum A, Halpern P, Geller E. The use of flumazenil in the management of acute drug poisoning—a review.
The question regarding how long the child was supervised for
http://emj.bmjjournals.com/cgi/content/full/18/1/34   (2764 words)

  
 Propofol versus Midazolam Regarding Their Antioxidant Activities -- TSUCHIYA et al. 163 (1): 26 -- American Journal of ...
Propofol versus Midazolam Regarding Their Antioxidant Activities -- TSUCHIYA et al.
Effects of 2,6-diisopropylphenol (Diprivan) and Midazolam on Peroxyl Radical-induced Impairment of Endothelium-dependent Relaxation of Aortic Ring Preparation
Concentration-response curves showing relaxation with acetylcholine on phenylephrine-contracted endothelium-containing rat aorta rings.
http://ajrccm.atsjournals.org/cgi/content/full/163/1/26   (3905 words)

  
 Using Intranasal Midazolam Spray to Prevent Claustrophobia Induced by MR Imaging -- Hollenhorst et al. 176 (4): 865 -- ...
technique for midazolam for clinical use in anxious patients.
For minor therapeutic and diagnostic procedures, midazolam seems
The purpose of this study was to examine the effect of midazolam
http://www.ajronline.org/cgi/content/full/176/4/865   (2183 words)

  
 Intranasal midazolam for febrile seizures -- Koren 321 (7253): 64 -- BMJ
midazolam may merely mean that both were not more effective than
slightly more quickly among those treated with midazolam when
What is the clinical significance of a two minute difference in the efficacy of the treatment of a benign condition?
http://bmj.bmjjournals.com/cgi/content/full/321/7253/64   (954 words)

  
 Buccal Midazolam - Family factsheets - GOSH and ICH
Your child may also have been prescribed rectal diazepam for epileptic fits lasting longer than five minutes.
Your child may not remember having an epileptic seizure
Midazolam belongs to a family of medicines known as benzodiazepines and it has a number of different medicinal uses.
http://www.ich.ucl.ac.uk/factsheets/families/F040014   (877 words)

  
 Premedication with nasal s-ketamine and midazolam provides good conditions for induction of anesthesia in preschool ...
Midazolam and ketamine have been used as premedicants for infants
Ghada el Saeidi, MD From the Clinic for Anesthesiology and Critical Care Medicine, University Hospital Kiel, Kiel, Germany.
Premedication with nasal s-ketamine and midazolam provides good conditions for induction of anesthesia in preschool children
http://www.cja-jca.org/cgi/content/full/50/5/470   (2091 words)

  
 BBC NEWS Health Medical notes Midazolam: the sedative drug
Midazolam is a sedative drug commonly used in medicine, but which can be dangerous in the wrong hands.
Midazolam can lead to the patient experiencing daydreams with a sexual content.
Midazolam is a benzodiazepine which is used as a sedative and to treat people who have gone into convulsions.
http://news.bbc.co.uk/2/hi/health/medical_notes/j-m/750437.stm   (198 words)

  
 Benzodiazepine withdrawal reaction in two children following discontinuation of sedation with midazolam -- van Engelen ...
Midazolam therapy was reinstituted and continued for another 2 months by constant infusion.
Four days later midazolam was again discontinued and within 12 hours the same signs and symptoms reappeared.
Unique in the very young children in this article is the occurrence of gastrointestinal symptoms, which most likely are the result of air being swallowed secondary to severe agitation.
http://www.theannals.com/cgi/content/abstract/27/5/579   (398 words)

  
 Intramuscular midazolam vs Intravenous diazepam for acute seizures Shah Ira, Deshmukh CT - Indian J Pediatr
Chamberlain et al demonstrated similar results as patients in the midazolam group received their medications sooner.
None of the patients in either group developed hypotension or respiratory depression though a significant number of patients in the diazepam group developed thrombophlebitis.
115 patients with acute convulsions were included in the study of which 50 patients were given IM midazolam and 65 patients were given IV diazepam.
http://www.ijppediatricsindia.org/article.asp?issn=0019-5456;year=2005;volume=72;issue=8;spage=667;epage=670;aulast=Shah   (1907 words)

  
 Versed Online, Description, Chemistry, Ingredients - Midazolam - RxList Monographs
For deeply sedated patients, a dedicated individual, other than the practitioner performing the procedure, should monitor the patient throughout the procedure.
At the physiologic conditions under which the product is absorbed (pH of 5 to 8) into the systemic circulation, any open-ring form present reverts to the physiologically active, lipophilic, closed-ring form (midazolam) and is absorbed as such.
Midazolam, a white to light yellow crystalline compound, is insoluble in water, but can be solubilized in aqueous solutions by formation of the hydrochloride salt in situ under acidic conditions.
http://www.rxlist.com/cgi/generic2/versedsyr.htm   (391 words)

  
 MIDAZOLAM - ORAL SYRUP (Versed) side effects, medical uses, and drug interactions.
Therefore, this drug must be used only under close medical supervision.
MIDAZOLAM - ORAL SYRUP (Versed) side effects, medical uses, and drug interactions.
WARNING: Use of midazolam can infrequently cause severe breathing problems (e.g., very slow, shallow breaths) which could cause brain damage or be fatal if left untreated.
http://www.medicinenet.com/midazolam-oral_syrup/article.htm   (405 words)

  
 CHEST: Propofol vs Midazolam for ICU Sedation - )
In situations in which patients could not give consent, surrogate consent was obtained from next-of-kin at the earliest possible time following ICU admission.
Patients in an ICU are exposed to a variety of noxious stimuli including pain after surgery, frequent venipuncture, and discomfort from the presence of an endotracheal tube.[1,2] Sedation is frequently required as a component of compassionate care in these patients.
As for the propofol group, in situations in which the rapid control of sedation was desired, an infusion bolus could be administered.
http://www.findarticles.com/p/articles/mi_m0984/is_4_119/ai_74293257   (824 words)

  
 Propofol and Midazolam Inhibit Gastric Emptying and Gastrointestinal Transit in Mice -- Inada et al. 99 (4): 1102 -- ...
Koh Shingu, MD Department of Anesthesiology, Kansai Medical University, Osaka, Japan
propofol or midazolam may be used to produce sedation.
light level of sedation, propofol may be preferable to midazolam
http://www.anesthesia-analgesia.org/cgi/content/abstract/99/4/1102   (262 words)

  
 Midazolam premedication reduces propofol requirements for sedation during regional anesthesia -- Nakagawa et al. 47 ...
The effects of midazolam on propofol-induced anesthesia: propofol dose requirements, mood profiles, and perioperative dreams.
patients received no premedication and in the midazolam group
in the midazolam group was 16.9% lower than in the control group.
http://www.cja-jca.org/cgi/content/full/47/1/47   (1053 words)

  
 EMS House of DeFrance
Sedative effect of midazolam may be accentuated by concomitant use of barbiturates, alcohol, or narcotics (it should therefore not be used in patients who have taken CNS depressants).
Midazolam HCl is a water-soluble benzodiazepine that may be administered for conscious sedation to relieve apprehension or impair memory before endotracheal or nasotracheal intubation.
Overdose Depressed vital signs Concomitant use of barbiturates, alcohol, narcotics, or other CNS depressants
http://www.kpemsc.org/pharm/midazolam.html   (125 words)

  
 A Prospective, Double-blind, Randomized Trial of Midazolam versus Haloperidol versus Lorazepam in the Chemical ...
IM Midazolam Superior to Lorazepam or Haloperidol for Sedating Violent Patients
81.9 minutes for patients receiving midazolam, 126.5 minutes
The mean difference between midazolam and lorazepam was
http://www.aemj.org/cgi/content/abstract/11/7/744   (466 words)

  
 PharmGKB: midazolam
Submitted by: Mark J. Ratain, MD involving CYP2B6, CYP2C19, CYP3A4,, meperidine, mephenytoin and midazolam.
Submitted by: Mary Relling, PharmD involving ABCB1, CYP3A4, CYP3A5, docetaxel, midazolam, and Neoplastic Processes.
Submitted by: Erin G. Schuetz, PhD involving CYP3A4, NR1I2,, amiodarone, cimetidine, dopamine, erythromycin, ethanol, glucocorticoids, midazolam, nicotine, phenobarbital, phenytoin, propofol, statin, thyroid and vasopressin.
http://www.pharmgkb.org/views/index.jsp?objCls=Drug&objId=PA450496   (207 words)

  
 Midazolam hydrochloride - definition of Midazolam hydrochloride in the Medical dictionary - by the Free Online Medical ...
Midazolam hydrochloride - definition of Midazolam hydrochloride in the Medical dictionary - by the Free Online Medical Dictionary, Thesaurus and Encyclopedia.
This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional.
A colorless crystalline derivative of diazepam with sedative and anxiolytic properties, usually used in its hydrochloride form as an intravenous anesthetic.
http://medical-dictionary.thefreedictionary.com/Midazolam+hydrochloride   (94 words)

  
 Midazolam - definition of Midazolam in Encyclopedia
Midazolam, also known by the trade names Versed® and Dormicum®, is a benzodiazepine with an imidazole structure.
Embed a dictionary search in your own web page
http://encyclopedia.laborlawtalk.com/Midazolam   (101 words)

  
 midazolam
NO PRIOR RX _ Common: uses This midazolam is an analgesic combination used to relieve pain.Find a pharmacy thats just right for you.
Read about any subject in the free online encyclopedia and dictionary.
Find midazolam at one of the best sites the clozapine has to offer!
http://carisoprodol.best-free-hosting.com/midazolam.html   (339 words)

  
 Erowid Midazolam (Versed) Vault : Images
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If you have photos you'd like to donate to Erowid's Image Vaults, we'd love to see them!
Color photo of a bottle of Midazolam HCl (5mg/ml).
http://www.erowid.org/pharms/midazolam/midazolam_images.shtml   (87 words)

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