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| | Distant metastases after irradiation alone in carcinoma of the uterine cervix |
 | | Bone metastases occurred in 16% of the patients, most commonly to the lumbar and thoracic spine. | | | A multivariate analysis of factors influencing the incidence of distant metastases showed clinical stage, endometrial extension noted by dilatation and curettage (DandC) prior to therapy, and pelvic tumor control within each stage to be significant indicators of distant dissemination; histology, volume of disease, and age of patient were not significant. | | | This is a retrospective analysis of 1211 patients with invasive carcinoma of the uterine cervix treated with irradiation alone from 1959 through 1986, of whom 322 developed distant metastases during the course of the disease. |
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http://www.meb.uni-bonn.de/cgi-bin/mycite?ExtRef=MEDL/92406565
(373 words)
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| | Metastatic Tumors to the Brain and Spine |
| | Symptoms of spinal fluid metastases are caused by irritation or compression of the brain and/or spinal cord and increased intracranial pressure. | | | Some metastases, such as those from small cell lung cancer or lymphoma, are very responsive to radiation therapy and surgery is often not considered. | | | Treatment for spinal metastases consists of chemotherapy and radiation therapy. |
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http://neurosurgery.mgh.harvard.edu/abta/mets.htm
(6591 words)
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| | Brain Metastases |
| | As stated earlier, radiosurgery is an appropriate substitute for surgical resection of single brain metastases that are technically difficult to resect or in whom patient comorbidities preclude surgery. | | | Although the data supporting surgery for single brain metastases were derived from relatively small, randomized trials that were not uniformly positive, the results generally have been interpreted to show that the surgical resection is of benefit in selected patients. | | | The concept of chemosensitizing brain metastases to radiation is intriguing; however, this therapy is experimental and cannot be recommended without supporting data from randomized trials. |
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http://www.aboutcancer.com/brain_metastases_arnold.htm
(6851 words)
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| | eMedicine - Bone Metastases : Article by Wilfred CG Peh, MBBS, MHSM, MD, FRCPE, FRCPG, FRCR |
| | In assessing the response to therapy, an increasing number of sclerotic bone metastases may be difficult to distinguish from the healing of sclerotic lesions that were not previously identified. | | | Its current value is in showing devascularization of vascular metastases prior to surgical intervention and in assessing pain palliation in patients with nonresectable metastases. | | | CT is useful in further assessment of radiographically negative areas in patients who are symptomatic and in whom metastases are suggested clinically. |
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http://www.emedicine.com/radio/topic88.htm
(5341 words)
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| | eMedicine - Brain, Metastases : Article by Anil Khosla, MD |
| | Brain metastases are less frequent in children, with an approximate incidence of 6%. | | | Radiosurgery provides a simple, effective, noninvasive, cost-effective method to treat surgically inaccessible lesions and is a therapeutic option for 2-6 metastases. | | | Nonenhancing lesions (see Image 12) are less likely to be metastases. |
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http://www.emedicine.com/radio/topic101.htm
(3946 words)
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| | Bone and Vertebral Metastases |
| | Increased incidence of bone metastases in hepatocellular carcinoma. | | | The regional bones close to the primary tumour were affected in 46% of the patients with bony mets, and the axial bones in 64%. | | | Complications from bone metastases include bone pain, fractures, hypercalcemia [too high level of calcium in the blood, which causes weakness and can create kidney failure], and compression of the spinal cord. |
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http://www.bctonline.com/~dwhiting/lms/metsbone1.htm
(3054 words)
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| | Liver Resections for Metastases - G. Nuzzo. IJSS 1995 Vol 2 NO 3 pp 94-99 |
| | The present study analyzes our experience with the surgical treatment of 63 cases of liver metastases from colorectal and non-colorectal cancers, with the goal of expanding the available information on the clinical correlates of long-term survival, and on the indications for surgery. | | | In 5 other patients with metastases from non-colorectal tumours, other surgical procedures were associated to the hepatic resection. | | | Perioperative mortality and morbidity rates and long-term results were evaluated in relation to: patients' age, type of primary tumour, features of metastases (disease-free interval, number, size), surgical technique (type and margin of resection, use of intraoperative blood transfusions), and use of adjuvant chemotherapy. |
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http://www.eass.it/ijss/3.199/Nuzzo.htm
(2959 words)
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| | Lung Cancer Online: Metastatic Disease - Brain Metastases |
| | Local control and freedom from new brain metastases is not influenced by prior external-beam radiotherapy. | | | Comprehensive guide for patients and caregivers intended to provide a basic understanding of brain metastases and their treatment. | | | Triple Therapy with Vinorelbine, Gemcitabine, and Carboplatin Demonstrates Efficacy Against Brain Metastases from NSCLC (Doctor's Guide) |
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http://www.lungcanceronline.org/treatment-mets/brain.html
(520 words)
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| | Metastases (mets) or how cancer spreads |
| | This is why it is most important for the doctors treating a patient to be able to establish the primary site at which any cancer originated. | | | The most common way for cancer to spread is through the lymphatic system. | | | Each type of cancer has its own pattern for metastases. |
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http://www.phoenix5.org/Basics/mets.html
(866 words)
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| | Bone metastases |
| | If bone metastases are not complicated by pathologic fracture or do not involve the spinal cord or nerve roots, treatment is dictated by symptoms, the risk of pathologic fracture, and the potential for effective systemic therapy. | | | In a randomized prospective trial of low- versus high- dose radiotherapy for bone metastases, 90% of patients achieved some pain relief and 54% eventually achieved complete relief from pain. | | | Tong D, Gillick L, Hendrickson FR: The palliation of symptomatic osseous metastases: final results of the study by the Radiation Therapy Oncology Group. |
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http://cancerweb.ncl.ac.uk/cancernet/103857.html
(1179 words)
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| | solitary contralateral adrenal metastases after nephrectomy for renalcell carcinoma |
| | The incidence of the localization in the adrenalsis probably explained by the type of adrenal blood supply, by their highflow volume and by the type of their capillary network, which has a sinusoidalvascular pattern. | | | Female, aged 68 years, underwent radical right nephrectomy for localizedrenal cancer 1 year ago (Fig.1).During surgery the existing embolus in the right renal vein was removed.Distant metastases were not found. | | | During a follow up examination 6 monthslater, the CT scan showed a suspicious enlargement of the left adrenal(Fig.2).The ultrasound tomography was not helpful in identifying the nature ofthe enlargement. |
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http://www.duj.com/Article/Antoniou.html
(1068 words)
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| | Survival of patients with metastases from uveal melanoma |
| | Prophylactic adjuvant therapy could be explored as a means to increase disease-free survival in patients with uveal melanoma. | | | Survival of patients with metastases from uveal melanoma. | | | Survival of patients with metastases from uveal melanoma |
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http://www.meb.uni-bonn.de/cgi-bin/mycite?ExtRef=MEDL/91219142
(197 words)
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| | Liver metastases |
| | Yet to be demonstrated is an improvement in survival in patients treated regionally versus those treated systemically. | | | One randomized trial showed a higher response rate in patients treated with intrahepatic chemotherapy but demonstrated no improvement in survival, primarily due to the development of extrahepatic metastases. | | | 2.Bozzetti F, Dolci R, Bignami P, et al.: Patterns of failure following surgical resection of colorectal cancer liver metastases: rationale for a multimodal approach. |
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http://www.uoc.muni.cz/guidelines/18sekund/MTSLIVER.htm
(885 words)
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| | Pharmacyclics.com - Brain Metastases smart clinical trials, motexafin gadolinium, xcytrin |
| | Informal conversations between the two about how Sessler, who was at that time a graduate student in chemistry at Stanford, might apply his knowledge to create novel treatments for cancer led to more focused laboratory experiment and conducting brain metastases clinical trials. | | | See our information on chronic lymphocyctic leukemia treatment provided in the above links. | | | Time to neurologic progression is a clinical benefit endpoint of special importance in patients with brain metastases since the majority of these patients experience neurologic decline despite the use of whole brain radiation therapy. |
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http://www.pharmacyclics.com
(707 words)
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| | Disease Category Listing (496): Brain Metastases |
| | A randomized trial of the role of whole brain radiation therapy in addition to radiosurgery in the management of patients with one to three cerebral metastases. | | | A study of conventional radiation therapy plus thalidomide vs. conventional radiation therapy for multiple brain metastases. | | | A randomized, double-blind, placebo-controlled, phase 3 study for the treatment of brain metastases from non-small cell lung cancer. |
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http://www.centerwatch.com/patient/studies/cat496.html
(2538 words)
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| | M1 |
| | Analyses of the causes of death within a year of surgery suggest that a third of patients have metastases. | | | Analysis of published studies on the detection of extrathoracic metastases in patients presumed to have operable non-small cell lung cancer. | | | In resected patients with Stage I cancers, metastases occurred in 15% with squamous cell carcinoma vs 27% with adenocarcinomas. |
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http://www.chestx-ray.com/StagingLungCa/M1.html
(204 words)
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| | Mesothelioma - Wikipedia, the free encyclopedia |
| | Surgery, either by itself or used in combination with pre- and post-operative adjuvant therapies has proved disappointing with a 5 year survival rate of less than 10%. | | | Although the tumour is highly resistant to radiotherapy and chemotherapy, these regimens are sometimes used to relieve symptoms arising from tumour metastases such as obstruction of a major blood vessel. | | | In February 2004, the Food and Drug Administration approved pemetrexed (brand name Alimta) for treatment of malignant pleural mesothelioma. |
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http://en.wikipedia.org/wiki/Mesothelioma
(3430 words)
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| | Cryotherapy, Ellis Fischel Cancer Center, University of Missouri Health Care |
| | Systemic chemotherapy is widely employed for unresectable disease and is associated with only a 20-40 percent response rate with little impact on long-term survival. | | | The use of cryotherapy to ablate remaining liver metastasis after chemotherapy should increase the number of patients with a complete clinical response and increase patient survival. | | | An additional 20 percent to 30 percent will develop liver metastases subsequent to treatment of their primary cancer. |
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http://www.ellisfischel.org/liver/cryotherapy.shtml
(757 words)
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| | Bone Metastases - Prostate Cancer Foundation |
| | If bone metastases are suspected, confirming the presence or extent of the cancer in the bones is an important first step in establishing a treatment plan. Imaging techniques can be helpful in determining where bone metastases are present. | | | Click here to read the 2004, Question and Anwser Form on Prostate Cancer and Bone Metastases. | | | Make the PCF homepage your start up site |
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http://www.prostatecancerfoundation.org/BoneMetastases
(60 words)
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| | Slavoj Zizek [Internet Encyclopedia of Philosophy] |
| | As we saw in 2e, Zizek’s Lacanian answer is that the perspective that one always presupposes when one speaks in this manner is one that is always “superegoic” (see 2a) — tied to what he terms in Metastases of Enjoyment a “malevolently neutral”, God’s eye view from nowhere. | | | For Zizek, accordingly, the critical question to be asked of any theoretical or political position that posits some exceptional Beyond, as we saw in his reading of Kant (2e) is: from which subjectposition do you speak when you claim a knowledge of this Beyond? | | | Tarrying With The Negative: Kant, Hegel And The Critique Of Ideology, Durham: Duke University Press, 1993. |
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http://www.iep.utm.edu/z/zizek.htm
(10966 words)
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| | LiverTumor.org - About Liver Cancer - Colorectal Liver Metastases |
| | Up to 70% of patients with colorectal cancer eventually develop liver metastases. | | | In 30-40% of those patients with metastases, it is still confined to the liver at the time of metastatic diagnosis. | | | A 1996 study reported five-year survival rates of 79%, with 52% of these patients not experiencing any recurrence during this period. |
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http://www.livertumor.org/about_colorectal.asp
(340 words)
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| | AllRefer Health - Liver Metastases Prognosis (Expectations) (Metastases to the Liver) |
| | AllRefer Health - Liver Metastases Prognosis (Expectations) (Metastases to the Liver) | | | You are here : AllRefer.com > Health > Diseases and Conditions > Liver Metastases: Prognosis of Liver Metastases | | | Patients with metastatic cancer to the liver usually die of their disease, however. |
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http://health.allrefer.com/health/liver-metastases-prognosis.html
(345 words)
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| | Randomized Trial of Open vs VATS for pulmonary metastases |
| | To test whether patients undergoing VATS will have a significantly better quality of life over a six month period than those undergoing an open resectin for the treatment of isolated pulmonary metastases, in terms of their physical symptoms,physical, vocational and social functioning,psychological state and body image. | | | To compare the overall survival between a minimally-invasive and open approach to the treatment of isolated pulmonary metastases. | | | To compare patterns of recurrence with minimally invasive and open approaches to the treatment of isolated pulmonary metastases, and to determine what factors are predictive of recurrence |
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http://www.ctsnet.org/doc/3091
(244 words)
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| | Your Online Hepatitis C Encyclopedia |
| | Hepatitis Central, An Appraisal of Percutaneous Treatment of Liver Metastases, Current Information On Hepatitis C and treatments for the medical professional and patient. | | | Hepatitis Central, Age at infection of hepatitis c virus and risk of hepatocellular carcinoma in cirrhosis, Current Information On Hepatitis C and treatments for the medical professional and patient. |
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http://hepatitis-central.com/sitemap.htm
(8475 words)
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