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Topic: Metastasis



  
 Metastasis - Wikipedia, the free encyclopedia
When cancer has metastasized, it may be treated with chemotherapy, radiation therapy, biological therapy, hormone therapy, surgery, or a combination of these.
Metastasis (Greek: change of the state) is the spread of cancer from its primary site to other places in the body.
Cancer researchers studying the conditions necessary for cancer metastasis have discovered that one of the critical events required is the growth of a new network of blood vessels.
http://en.wikipedia.org/wiki/Metastasis

  
 Bone Metastasis Information
The goal of treatment is to decrease pain, prevent further bone breakdown and to restore function to patients with bone metastasis.
As well as to provide bone metastasis patients and community oncologists a clinic visit where all the opinions necessary and appropriate for this patient population will be given.
Bone metastasis to the long bones of the arms and legs can cause pain with activity and occasionally that pain can be relieved with rest.
http://www.cancer.med.umich.edu/learn/bonemetfaq.htm

  
 Management of Ocular Metastasis
Intraocular metastasis is a significant and under-recognized clinical problem for the practicing ophthalmologist and oncologist.
The specific therapy chosen for a patient is an individualized process that considers the clinical condition of the patient.
Background: Intraocular metastasis is a significant clinical problem in patients with metastatic cancer.
http://www.moffitt.usf.edu/pubs/ccj/v5n4/article4.html

  
 ACS :: How Is Bone Metastasis Treated?
If you can’t have surgery to reinforce a bone affected by metastasis (because of poor general state of health, other complications of the cancers, or side effects of other treatments) a cast may help stabilize leg bones to reduce pain and avoid the need to stay in bed.
Although surgery to remove a primary bone tumor (one that started in the bone) is often done with the intent to cure, the purpose of treating a bone metastasis surgically is to relieve symptoms.
This approach is useful in treating some primary cancers and some metastases, but it is not often used for treating bone metastasis.
http://www.cancer.org/docroot/CRI/content/CRI_2_4_4X_How_Is_Bone_Metastasis_Treated_66.asp?sitearea=

  
 Metastatic Tumors to the Brain and Spine
Metastasis is the spread of cancer from one part of the body to another.
The most common symptoms of brain metastasis are headache, muscle weakness and behavioral disturbances.
The incidence of central nervous system metastasis of lymphoma is increasing because the incidence of that form of cancer is increasing.
http://neurosurgery.mgh.harvard.edu/abta/mets.htm

  
 Novartis Oncology - Bone Metastasis
Other treatments for bone metastases and their symptoms include physical therapy and drug and nondrug approaches to control pain.
Side effects of radiation therapy may include skin changes in the area being treated and a temporary increase in symptoms of bone metastasis.
The doctor can help you distinguish between pain from metastasis and aches and pains from other sources.
http://www.novartisoncology.com/page/bone_metastases.jsp

  
 Metastases (mets) or how cancer spreads
This is why it is most important for the doctors treating a patient to be able to establish the primary site at which any cancer originated.
metastasis (meh-TAS-ta-sis): The spread of cancer from one part of the body to another.
This can happen accidentally when a biopsy is done or when cancer surgery is performed.
http://www.phoenix5.org/Basics/mets.html

  
 Bone Metastasis Information
The goals of any treatment are to lessen pain, prevent further bone breakdown, and restore function to patients with bone metastasis.
Diagnosing bone metastasis in patients with arthritis or osteoporosis can be especially challenging.
What you need to know about bone metastasis, cancer, a glossary and what the future holds for bone metastasis understanding and treatment.
http://www.cancer.med.umich.edu/learn/bonemetsfacts.htm

  
 Cancer control Journal: Melanoma Metastasis
Although experimental analysis of cancer metastasis is performed in laboratory animals, ethical considerations preclude this analysis in human patients.
Theoretically, the differences in site-specific brain metastasis observed among the different melanomas could be due to different behaviors at different steps of the metastatic process.
An understanding of the mechanisms that regulate the pathogenesis of metastasis will lead to the ability to design more effective therapy for malignant melanoma.
http://www.moffitt.usf.edu/pubs/ccj/v2n5/article3.html

  
 SABCS: Herceptin (Trastuzumab) Spares Bone from Metastasis but Leaves Brain Unprotected
One of the 23 patients (4 percent) without bone metastasis at the start of Herceptin therapy subsequently developed bone metastasis on therapy (p<0.05).
Lower and colleagues conducted a study to determine the incidence of brain metastasis in patients receiving Herceptin compared to those not receiving Herceptin.
Lower said that in contrast, about 10 percent of patients with advanced breast cancer would be expected to develop brain metastases without Herceptin therapy.
http://www.docguide.com/dg.nsf/PrintPrint/5608E1B980DC4A4085256B21004C264E

  
 ACS :: What Is Bone Metastasis?
Many people with cancer (except for those with non-melanoma skin cancer) develop bone metastasis at some point in the course of their disease.
The spine is the part of the skeleton most commonly affected by bone metastasis.
Primary bone cancer is much less common than bone metastasis.
http://www.cancer.org/docroot/CRI/content/CRI_2_4_1X_What_Is_bone_metastasis_66.asp

  
 Neoplasm Metastasis
The journal covers articles on the study of cancer and the search for effective therapeutic modalities for this disease.
United States; Patient Education; Neoplasm Metastasis; Diphosphonates; Bone Neoplasms / drug therapy;
The homepage for the journal Clinical and Experimental Metastasis.
http://omni.ac.uk/browse/mesh/D009362.html

  
 Breast Cancer Research Full text Molecular analysis of metastasis in a polyomavirus middle T mouse model: the role of ...
From both a clinical and experimental perspective, a more detailed understanding of the mechanisms of metastasis is needed in order to identify better diagnostic markers and therapeutic approaches.
We therefore conclude that OPN is essential for metastasis in the PyV-mT system, but that elevated OPN expression alone is not sufficient to induce metastasis.
The results of these experiments demonstrate that OPN is essential for the metastatic phenotype in PyV-mT, but that it alone is not sufficient to produce the metastatic phenotype.
http://breast-cancer-research.com/content/6/3/R157

  
 World Journal of Surgical Oncology Full text Unusual metastasis of papillary thyroid carcinoma to larynx and ...
Known sites of distant spread in PCT are bone, lung, skin and brain while involvement of recurrent laryngeal nerve, larynx, pharynx, trachea and esophagus occurs due to direct infiltration [2].
Tobias MJ: Anatomy of the Human Lymphatic System: A compendium translated from the original 'Anatomie des Lymphatiques de l 'Homme 'by H. Rouviere rearranged for the use of students and practitioners.
Advanced thyroid malignancies generally presents difficult therapeutic decisions especially when there is extra nodal and extra capsular spread of the tumor.
http://www.wjso.com/content/1/1/7

  
 NeurosurgeryToday.org What is Neurosurgery Patient Education Materials brain metastasis
The incidence of brain metastasis is based on age.
Although virtually any malignancy can metastasize, or spread, to the brain, the incidence of brain metastasis varies dramatically from one type of cancer to another.
However, gene therapy for brain metastasis is still in its infancy.
http://www.neurosurgerytoday.org/what/patient_e/brain1.asp

  
 Nucleoside Diphosphate Kinase A/nm23-H1 Promotes Metastasis of NB69-Derived Human Neuroblastoma -- Almgren et al. 2 ...
Nucleoside Diphosphate Kinase A/nm23-H1 Promotes Metastasis of NB69-Derived Human Neuroblastoma -- Almgren et al.
a metastasis promoter at least in human neuroblastoma derived
Nucleoside Diphosphate Kinase A/nm23-H1 Promotes Metastasis of NB69-Derived Human Neuroblastoma
http://mcr.aacrjournals.org/cgi/content/abstract/2/7/387

  
 Joint Program in Nuclear Medicine
Boxer et al reported that 88% of patients with a single bone metastasis were in the spine.
The risk of developing bone metastasis increases with the stage of the disease at presentation.
In Boxer et al's series of breast cancer patients with relapse to bone, 21% of patients relapsed to bone with a single demonstrable metastasis.
http://www.med.harvard.edu/JPNM/TF93_94/Oct26/WriteUpOct26.html

  
 Selectins Facilitate Carcinoma Metastasis and Heparin Can Prevent Them -- Borsig 19 (1): 16 -- Physiology
Although most of the studies were focused on the tumorigenesis
the known function of platelets in facilitating metastasis,
Selectins Facilitate Carcinoma Metastasis and Heparin Can Prevent Them
http://physiologyonline.physiology.org/cgi/content/full/19/1/16

  
 National Cancer Institute - Dictionary of Cancer Terms
Having to do with metastasis, which is the spread of cancer from one part of the body to another.
The spread of cancer from one part of the body to another.
Cancer that has spread from the place in which it started to other parts of the body.
http://www.cancer.gov/dictionary/db_alpha.aspx?expand=m

  
 Curriculum Vitae: Professor Garth L. Nicolson
International Congress on Cancer Metastasis: Biological and Biochemical Mechanisms and Clinical aspects.
Speaker in the Session on Functional Aspects of Oncogenes: Tumor Diversification and Metastasis.
Chaired and presented in Session II on Invasion and Metastasis.
http://www.immed.org/cv/_GLN-CV_01_10_30.html

  
 Colon Cancer Metastasis
When colon cancer has been detected or has returned following an initial treatment with surgery, radiation therapy and/or chemotherapy it is said to be recurrent or relapsed.
Our work uses microarray analysis and proteomics to study tumor metastasis with a focus on colon cancer
Once metastasis has occurred in colorectal cancer, a complete cure of the cancer
http://www.colon-cleanse-products.com/cleansing/colon-cancer-metastasis.html

  
 Protection from Lymphoma Cell Metastasis in ICAM-1 Mutant Mice: A Posthoming Event -- Aoudjit et al. 161 (5): 2333 -- ...
Cancer metastasis and angiogenesis: an imbalance of positive and negative regulation.
as a focus of future investigation on the control of metastasis mediated
The resistance to lymphoma metastasis that was observed in ICAM-1-deficient
http://www.jimmunol.org/cgi/content/full/161/5/2333

  
 Cancer Spectrum: Steeg, pp. E4
Breast cancer metastastic potential correlates with a breakdown in homospecific and heterospecific gap junctionalintercellular communication.
Evidence for interaction between human PRUNE and nm23-H1 NDPKinase.
Melanoma metastasis suppression by chromosome 6: evidence for a pathway regulated by CRSR3 and TXNIP.
http://jncicancerspectrum.oupjournals.org/cgi/content/full/jnci%3B96/6/E4

  
 Expression of Vascular Endothelial Growth Factor C and D (VEGF-C and -D) is an Important Risk Factor for Lymphatic ...
Department of Surgery, Division of Surgical Oncology, The University of Tokyo, Tokyo, Japan
metastasis, while the positive expression of VEGF-D suggests
of VEGF-C and -D and lymphatic metastasis in early gastric cancers.
http://jjco.oupjournals.org/cgi/content/abstract/33/1/21

  
 METASTASIS
A cancer which spreads from its primary focus to a distant (non-adjacent) site is referred to as a metastasis.
Copyright DSHI Systems, Inc., Last updated Feb. 2002
http://www.medhelp.org/glossary2/new/GLS_3102.HTM

  
 Dr. Watabe at the Department of Medical Microbiology and Immunology
The development of metastasis is a major obstacle to the successful treatment of a patient with any cancer.
Although the clinical importance of the tumor metastasis is well recognized, advances in understanding the molecular mechanism involved in metastasis formation have lagged behind other developments in the cancer field.
The studies of our laboratory focus on the molecular mechanism of tumor metastasis.
http://www.siumed.edu/mmi/watabe.htm

  
 Metastasis Research Group
This theme is based on our study on this molecule in human cancer, in the past decade.
Current research has focused mainly on the following fronts:
The molecular impact of hepatocyte growth factor (HGF) in the development of cancer metastasis and the therapeutic implications thereof.
http://www.uwcm.ac.uk/mrg

  
 Sloan-Kettering - Projects: Oncology and Mechanisms of Metastasis
When the TGF-ß pathway is corrupted by the action of oncogenes, the cell may respond to TGF-ß with a highly malignant behavior.
Osteolytic bone metastasis is a major cause of morbidity in breast cancer patients.
Metastasis -- the spread and growth of tumor cells to vital organs -- is the ultimate cause of death in the vast majority of cancer patients.
http://www.mskcc.org/mskcc/html/10619.cfm

  
 Dr. Koop - Breast Cancer Metastasis- Health Encyclopedia and Reference
With proper surgery and systemic treatments, there is still a good chance that all cancer can be removed from the body.
A woman may be found to have a distant metastasis of her breast cancer at the time when her initial breast cancer is found, or months to years later.
This occurs because breast cancer cells can escape from the breast before surgery and may take a long time to form a tumor in another part of the body.
http://www.drkoop.com/encyclopedia/43/484.html

  
 Lectin binding to cutaneous malignant melanoma: HPA is associated with metastasis formation
Cox regression analysis demonstrated that even after adjustment for stage, HPA positivity is an independent predictor for metastasis.
This study analysed the association between lectin binding and metastasis in cutaneous malignant melanoma.
Meier analysis of time to first metastasis revealed a positive correlation between HPA binding and metastasis for both methods, with the biotinylated HPA method (P< 0.0001) being superior to the 'indirect' method (P = 0.0006).
http://www.nature.com/cgi-taf/dynapage.taf?file=/bjc/journal/v84/n6/abs/6691673a.html

  
 RESPONSIBILITIES OF MEMBERSHIP
Our goal is to contribute to the cure of cancer by research, education, and communication regarding the most deadly aspect of cancer -- metastasis.
The Metastasis Research Society (MRS), a scientific society of laboratory, translational, and clinical researchers, was founded in 1984.
Details regarding nomination and membership approval process can be found in the bylaws.
http://www.metastasis-research.org/responsibilities_of_membership.htm

  
 Members Area Test
Please visit often to learn about what is happening in the world of metastasis research and treatment.
If you are interested in joining the Metastasis Research Society but want more information, click here.
Welcome to the Official Website for the Metastasis Research Society.
http://www.metastasis-research.org

  
 metastasis - OneLook Dictionary Search
Metastasis : Drug Discovery and Development [home, info]
Words similar to metastasis: metabolism, metastases, metastatic, metastatically, metabolic process, metasteses, more...
metastasis : The On-line Medical Dictionary [home, info]
http://www.onelook.com/?w=metastasis&ls=a

  
 Suppression of Natural Killer Cell Activity and Promotion of Tumor Metastasis by Ketamine, Thiopental, and Halothane, ...
on resistance to experimental metastasis, and studied mediating
IMPLICATIONS: This study in a rat model of pulmonary metastasis
Suppression of Natural Killer Cell Activity and Promotion of Tumor Metastasis by Ketamine, Thiopental, and Halothane, but Not by Propofol: Mediating Mechanisms and Prophylactic Measures -- Melamed et al.
http://www.anesthesia-analgesia.org/cgi/content/abstract/97/5/1331

  
 Nm23-H1 Metastasis Suppressor Phosphorylation of Kinase Suppressor of Ras via a Histidine Protein Kinase Pathway -- ...
From the Women's Cancers Section, Laboratory of Pathology, Center for Cancer Research, NCI, National Institutes of Health, Bethesda, Maryland 20892 and the
aggressive clinical course (patient survival, lymph node metastasis,
Data from replicate experiments were normalized to the C-100 control transfectant as 0.5 pMAPK/MAPK, and the mean and S.E. of three replicate experiments is shown.
http://www.jbc.org/cgi/content/full/277/35/32389

  
 Vascular Growth Factors and Lymphangiogenesis -- Jussila and Alitalo 82 (3): 673 -- Physiological Reviews
metastasis by increasing vascular permeability, by changing the
This pattern of metastasis is central to the utility of the sentinel
The presence of a metastasis in a lymph node does not necessary mean that the tumor cells have been arrived via the lymphatic
http://physrev.physiology.org/cgi/content/full/82/3/673

  
 Lung Metastasis Clinical Resources
Metastasis: Determining Risk and Developing Therapeutic Strategies: Access document
Chapter 4 - Biology of Cancer Metastasis: Access document
Evaluation of the Solitary Pulmonary Nodule: Access document
http://cchs-dl.slis.ua.edu/clinical/oncology/metastatic/lungmetastasis.html

  
 Prostaglandin E2 Suppresses NK Activity In Vivo and Promotes Postoperative Tumor Metastasis in Rats -- Yakar et al. 10 ...
as rats’ resistance to experimental metastasis of a syngeneic
Suppresses NK Activity In Vivo and Promotes Postoperative Tumor Metastasis in Rats
Prostaglandin E2 Suppresses NK Activity In Vivo and Promotes Postoperative Tumor Metastasis in Rats -- Yakar et al.
http://www.annalssurgicaloncology.org/cgi/content/abstract/10/4/469

  
 The Leading Metastasis and Angiogenesis Models
Develop New Effective Drugs for Metastasis and Angiogenesis
Green/Red Fluorescent Protein to visualize, image and quantify drug efficacy on tumor growth, metastasis, angiogenesis and gene expression in real time.
• Whole-body functional imaging of drug efficacy on tumor growth, metastasis, angiogenesis, gene expression.
http://www.metamouse.com

  
 ACS :: Detailed Guide: Bone Metastasis
What's New in Bone Metastasis Research and Treatment?
What Are the Risk Factors for Bone Metastasis?
What Should You Ask Your Doctor About Bone Metastasis?
http://www.cancer.org/docroot/cri/cri_2_3x.asp?dt=66

  
 Integrin Cytoplasmic Domain-associated Protein 1alpha (ICAP-1alpha ) Interacts Directly with the Metastasis Suppressor ...
Nucleoside Diphosphate Kinase A/nm23-H1 Promotes Metastasis of NB69-Derived Human Neuroblastoma
and nm23-H2 may drastically change the understanding of the metastasis suppressor
Notably, nm23-H2 has been described as a metastasis
http://www.jbc.org/cgi/content/full/277/23/20895

  
 Metastasis
In late stages, patients with oral cancer for example, may succumb to a cancer in the lungs or the brain, which was not the location of the original, primary tumor.
The lungs and the liver are the two most common sites for metastasis in the human body.
Metastasis most commonly occurs by way of the bloodstream or the lymphatic system.
http://www.oralcancerfoundation.org/facts/metastasis.htm

  
 Breast Cancer Dictionary - M
metastasis -- The spread of cancer cells to distant areas of the body by way of the lymph system or bloodstream.
http://www.jsonline.com/alive/news/cancer/mterms.asp

  
 BIO349 - Metastasis - Introduction
Cancer is one such disease, and cancer cell migration occurs in a process termed metastasis (Lodish, 2002).
Experiments on model organisms, whose many metabolic processes parallel our own, help us to understand the underlying factors that are involved in causing cancer and other diseases, and the effects various treatments might have on humans (Griffiths, 2002).
Model organisms, such as the fly (Drosophila melanogaster) and the mouse, provide us means by which we can perform experiments to study the alterations that lead to cancer (Griffiths, 2002).
http://dragon.zoo.utoronto.ca/~B03T9902A/introduction.htm

  
 Cancer Treatment Research Foundation: Glossary
metastasis: The spread of cancer from one part of the body toanother.
For example, cancer that starts in the breast can spread to the lymph nodes and then be spread throughout the body.
http://www.ctrf.org/glossary.cfm

  
 AllRefer Health - Metastasis (Cancer Metastases, Metastatic Cancer)
AllRefer Health - Metastasis (Cancer Metastases, Metastatic Cancer)
Metastasis is the movement or spreading of cancer cells from one organ or tissue to another.
You are here : AllRefer.com > Health > Special Topic > Metastasis
http://health.allrefer.com/health/metastasis-info.html

  
 Metastasis definition - Cancer information on MedicineNet.com
For example, someone with melanoma may have a metastasis in their brain.
The process by which cancer spreads from the place at which it first arose as a primary tumor to distant locations in the body.
Metastasis depends on the cancer cells acquiring two separate abilities -- increased motility and invasiveness.
http://www.medterms.com/script/main/art.asp?articlekey=4363

  
 World Journal of Surgical Oncology Full text Pancreatic metastasis from gastric carcinoma: a case report
The pancreas is an uncommon location for solitary metastasis from other primary cancers [1].
Whereas renal cell carcinoma appears to be the most common primary tumor to cause secondary pancreatic tumors, a variety of other cancers may spread to the pancreas, such as colon cancer, non-small cell lung cancer, and sarcomas [3].
Furthermore, solitary metastasis in other organs, such as the thyroid gland or the spleen have been described [6,7].
http://www.wjso.com/content/2/1/43

  
 New Scientist Breaking News - Stem cell mobility linked to cancer's spread
A cancer vaccine based on the molecule has already been successfully trialled in humans and a "magic bullet" treatment is also in development.
As cancers grow, cells often move out of the original tumour and spread around the body using the blood or lymphatic system, a process called metastasis.
http://www.newscientist.com/article.ns?id=dn4309

  
 Metastasis
Depending on certain circumstances, treatment of metastatic disease may be accomplished by Surgery, Radiation or Chemotherapy.
An effort should be made to determine the extent of every cancer and the potential sites of metastasis must be studied.
Cough, shortness of breath due to Lung metastasis
http://www.tirgan.com/metastasis.htm

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