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 Merck & Co. - Wikipedia, the free encyclopedia
Thereafter, studies by Merck and by others found an increased risk of heart attack associated with Vioxx use when compared with Naproxen (an established drug used for treating arthritis).
Merck has published the Merck Manual of Medical Information since 1899, which has been used by doctors and families alike.
On September 23, 2004, Merck received information about results from a clinical it was conducting that supported previous findings of increased risk of heart attack among Vioxx users.
http://en.wikipedia.org/wiki/Merck_&_Co.   (837 words)

  
 The Murky History of Merck's Vioxx
Merck says rates of cardiovascular risk were "similar" among patients taking Vioxx, placebo or other pain relievers.
November 1998: Merck submits application to Food and Drug Administration seeking approval for the COX-2 inhibitor drug, Vioxx, as a treatment for osteoarthritis, on the basis of clinical trials involving 5,400 patients.
FDA posts a more detailed version of the study on its Web site in November, but says the article hasn't been subject to standard peer review.
http://www.thestreet.com/_googlen/stocks/biotech/10195104.html?cm_ven=GOOGLEN&cm_cat=FREE&cm_ite=NA   (602 words)

  
 USATODAY.com - Lawyer: Merck more about profits than healing
Merck knowingly put patients at risk by relying on limited animal studies to say its arthritis drug Vioxx would not harm the heart and ignoring human data that suggested otherwise, an advocacy group said Thursday.
Merck wants to focus on science, arguing that no studies link Vioxx to arrhythmia.
He had been taking Vioxx to ease pain in his hands.
http://www.usatoday.com/money/industries/health/drugs/2005-07-14-vioxx-trial_x.htm   (753 words)

  
 Merck & Co.
One of Merck’s more dramatic successes is HIV drug Crixivan, which reduced AIDS-related deaths by 60 percent after just 18 months on the market.
The company conducts most of its research and development at its own laboratories, unlike larger competitors who rely on licensing drugs from other companies and outsource up to 80 percent of their research.
Publishes the Merck Manual, one of the most widely used medical texts in the world
http://www.wetfeet.com/asp/companyprofiles.asp?companypk=142   (228 words)

  
 How murky is Merck outlook? - Dec. 6, 2004
For Merck, lingering concerns about the recall of its arthritis drug Vioxx in September because of studies linking the medication to heart attacks will likely weigh on the stock for the next year.
The drug is still in late-stage clinical studies.
Plus, he thinks Merck will be fairly aggressive in defending itself.
http://money.cnn.com/2004/12/06/news/fortune500/merck   (880 words)

  
 Merck's Missing Vioxx Study - Forbes.com
Merck spokesman Tony Plohoros says that Merck's statement at the analyst meeting referred to its plan to gather and combine heart-safety data from three other studies, whose primary aim was to show Vioxx could prevent or treat cancer.
In December of 2001, Merck seemed to indicate it would mount such a study--but the clinical trial never seems to have materialized, even though the firm started a similar trial for Arcoxia, a successor drug to Vioxx.
According to Merck's press release from its 2001 annual meeting with Wall Street analysts, the company "announced plans to conduct a large cardiovascular clinical outcomes study with Vioxx and a separate cardiovascular outcomes trial with Arcoxia.
http://www.forbes.com/sciencesandmedicine/2004/10/14/cx_mh_1014vioxx.html   (889 words)

  
 Bloomberg.com: U.S.
Trial lawyers and some doctors say Merck should have known as early as 2000 that the drug might be dangerous.
Gilmartin, 63, has said Merck will rely on existing medicines to expand earnings and sales, specifically Singulair, for asthma and allergies; Fosamax, for osteoporosis; and Cozaar, for high blood pressure.
U.S. regulators estimate that Vioxx may have contributed to 27,785 heart attacks and deaths before it was pulled in the biggest drug recall ever.
http://www.bloomberg.com/apps/news?pid=10000103&sid=aepGEeSrdUdk&refer=us   (856 words)

  
 [No title]
Undisclosed company documents show that the drug maker was in the process of beginning a major cardiovascular study of the drug in 2002, and suddenly dropped the project just before it was set to start.
It is reprehensible behavior that any company would put their profits ahead of the health and safety of children.
Mercola encourages you to make your own health care decisions based upon your research and in partnership with a qualified health care professional.
http://www.mercola.com/2005/feb/23/merck_coverups.htm   (1122 words)

  
 Merck caught in scandal to bury Vioxx heart attack risks, intimidate scientists and keep pushing dangerous drugs; Vioxx ...
Even the medical journals are astonished at Merck's behavior.
One email, authored by Edward Scolnick, chief of research for Merck, says that cardiovascular risks, "...are clearly there." Additional emails contribute to the evidence that points to a fairly straightforward case of consumer deception.
Merck has even been caught red-handed trying to suppress negative information about its drugs.
http://www.newstarget.com/002155.html   (1324 words)

  
 Merck
But the Merck memo shows that at least one major manufacturer was aware of the concern much earlier.
They cite a report in May by a committee of the national Institute of Medicine concluding that the evidence "favors rejection of a causal relationship" between vaccines and autism.
Reached at home, Laser, 55, declined to comment.
http://www.vaccinetruth.org/merck.htm   (2051 words)

  
 Vioxx news slams Merck stock - Friday, 10/01/04
Gilmartin already was dealing with disappointing study data involving Merck's top medicine, Zocor for cholesterol.
Before yesterday's recall of Vioxx, the biggest drug ever withdrawn was Bayer AG's cholesterol medicine Baycol, which was pulled off the market in August 2001 after it was linked to 52 deaths worldwide.
With $1 billion in sales, the drug was Bayer's No. 3 medicine and its fastest growing.
http://www.tennessean.com/business/archives/04/09/58779741.shtml?Element_ID=58779741   (874 words)

  
 Merck - SourceWatch
Vioxx is the brand name for Merck's anti-inflammatory drug and pain medication, initially marketed as an alternative to analgesics that aggravate stomach ulcers.
Also, more than 40 percent of the ads in the campaign are being devoted to information about what Merck calls its access programs, which are efforts to provide some consumers with prescription drugs either free or at reduced prices.
The documents show that Merck exerted pressure not only on individual doctors, but also on several of the nation's top medical schools." [12] (http://www.npr.org/templates/story/story.php?storyId=4696609)
http://www.sourcewatch.org/wiki.phtml?title=Merck   (1343 words)

  
 The Motley Fool: Dueling Fools, Merck Bear's Den
Merck's newest drugs will not be able to fully replace the revenue: Propecia, for hair-loss replacement; Maxalt, for migraines; Singulair, an asthma drug; Aggrastat, an anti-coagulant; Vioxx, an anti-arthritic pain reliever, and Cosopt, for treatment of glaucoma, will be lucky to generate $3.5 billion in sales by 2001.
Even Merck's potential future powerhouse, the pain reliever and arthritis drug Vioxx, which is supposed to be kind of a "super-Advil," will face competition the minute it hits the market from a drug developed by Monsanto (NYSE: MTC) and marketed by Pfizer.
While this is a predictable criticism that has been leveled at Merck before, it is still a legitimate concern, especially when one considers Merck's relatively low level of research and development (R&D) spending.
http://www.fool.com/DuelingFools/1998/DuelingFools981111mrk002.htm   (942 words)

  
 USATODAY.com - Merck halts Vioxx sales
Drugmakers say they treat arthritis pain but are less irritating to the gastrointestinal tract than traditional NSAIDs.
In August, an FDA-funded analysis involving Kaiser Permanente patients found more heart attacks and sudden cardiac deaths among people taking Vioxx than among those on Celebrex or on conventional nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen and aspirin.
"It is important to note that the results of clinical studies with one drug in a given class are not necessarily applicable to others in a class," says Peter Kim, president of Merck Research Laboratories.
http://www.usatoday.com/money/industries/health/drugs/2004-09-30-vioxx-withdrawn_x.htm   (551 words)

  
 BW Online March 26, 2004 Turning Merck Around -- Again
The perception of Merck and its research changed quite dramatically.
Our opportunity to start turning around that perception again is when the two drugs that we have before the FDA right now get approved, Vytorin and Arcoxia.
Q: Let me turn a bit more personal.
http://www.businessweek.com/technology/content/mar2004/tc20040326_7650_tc057.htm   (1534 words)

  
 Merck KGaA - Life Science & Analytics / Food and Environmental Analysis
Merck KGaA - Life Science and Analytics / Food and Environmental Analysis
http://service.merck.de/microbiology   (12 words)

  
 Amazon.com: Books: The Merck Manual Of Medical Information (Merck Manual of Medical Information, Home Ed. (Mass Market ...
Over the years many books have been published that are medical in nature, some published by doctors, but the content is watered down or so vague that a layperson doesn't derive much information from it.
If you are looking for a book about children's ailments that encompasses not only western medicine but lists an array of other treatment methods, I suggest Smart Medicine for a Healthier Child: A Practical A-To-Z Reference to Natural and Conventional Treatments for Infants and Children by Janet Zand.
Clear drawings of basic anatomical details and helpful sidebars that define terms and proffer advice are invaluable features, as is the up-to-date counsel on choosing the right form of exercise.
http://www.amazon.com/exec/obidos/tg/detail/-/0671027271?v=glance   (2241 words)

  
 Kevin, M.D. - Medical Weblog: Vioxx and Merck: Saturday update
That money could be used to research better drugs or even cures to current diseases.
This is way below the 18-months of usage that some studies show might slightly increase the risk of arrhythmias.
The verdict wasn't just based on the medical evidence, however.
http://www.kevinmd.com/blog/2005/08/vioxx-and-merck-saturday-update.html   (1413 words)

  
 Merck & Co., Inc. is a global research-driven pharmaceutical company dedicated to putting patients first.
Merck's position on clinical trials registries and results
Read the latest news on Merck medicines and vaccines
Agensys and Merck Announce Agreement to Co-Develop and Commercialize a Novel Antibody for Cancer Therapy
http://www.merck.com   (100 words)

  
 Merck & Co., Inc. - Fact Sheet - Hoover's
Merck also makes painkillers such as Arcoxia, male pattern baldness treatment Propecia, and asthma drug Singulair.
After studies suggested Vioxx, its blockbuster arthritis pain medication, increased the risk of heart attacks and stroke, Merck pulled it from the shelves.
Vioxx might return, though, after an FDA review green-lighted the drug.
http://www.hoovers.com/co/capsule/6/0,2163,10986,00.html   (362 words)

  
 About Merck Research Labs
Equally important is the information we've included to help you explore career opportunities at MRL that match your background, experience, and goals.
We've created this site to help you learn about our work and our people, as well as our research philosophy, culture, and values.
Interested in a Career at Merck Research Labs?
http://www.merck.com/mrl   (238 words)

  
 Merck Merial Summer Research Programs, College of Veterinary Medicine and Biomedical Sciences, Colorado State University
The objective of this program is to provide a positive research experience for first and second year veterinary students by integrating them into our basic and clinical science research projects.
Merck Merial Summer Research Programs, College of Veterinary Medicine and Biomedical Sciences, Colorado State University
http://www.cvmbs.colostate.edu/Merck-MerialSummerResearchProgram   (267 words)

  
 Patients' Pages
Merck KGaA manages this web site to help improve communication between doctors and patients about HRT.
If you have any questions, comments or suggestions for improvements, please contact us.
If you are currently a Fem7 user and you want more information about Fem7 products, or about how to put on your patch, click 'About Fem7'.
http://www.fem7.com   (103 words)

  
 The Trentonian - News - 11/07/2004 - Vioxx shockwaves rock Merck
And questions are continuing to arise concerning Merck’s actions regarding the development, marketing and subsequent removal of Vioxx.
Merck removed Vioxx after a three-year study revealed patients taking Vioxx more than 18 months increased their risk for heart attacks and strokes.
When Merck removed Vioxx, a rofecoxib, part of the Cox-2 inhibitor class of drugs, it was based upon a new, three-year APPROVe (Adenomatous Polyp Prevention) study that revealed patients taking Vioxx more than 18 months increased their risk for heart attacks and strokes.
http://www.zwire.com/site/news.cfm?newsid=13312847&BRD=1697&PAG=461&dept_id=44551&rfi=6   (1144 words)

  
 Report: Merck Played Down Vioxx Risks
For several years before and after Vioxx was approved for commercial use, executives of Merck (MRK:NYSE - commentary - research) were reportedly aware of -- and tried to play down -- the drug's potential risk for causing cardiovascular problems such as heart attack and stroke.
Merck withdrew Vioxx from the market on Sept. 30, saying that a company-sponsored study had shown that long-term use of the drug -- longer than 18 months -- raised the risk of cardiovascular problems when test results of Vioxx users were compared with people taking placebo.
However, during a period of less than 18 months, the company said there was no statistically significant difference in heart and stroke issues between Vioxx patients and people taking placebo.
http://thestreet.com/_yahoo/stocks/biotech/10191714.html?cm_ven=YAHOO&...   (481 words)

  
 CBC News: Merck knew of Vioxx health risks: report
Before the company pulled the drug on Oct. 1, Vioxx had been one of Merck's blockbuster drugs, responsible for 12 per cent of the drug company's revenue.
Merck withdrew it after new data from a clinical trial found an increased risk of heart attack and stroke after 18 months of use.
The newspaper reported that internal company e-mail and documents showed the company knew as early as 2000 of the health concerns surrounding Vioxx but tried to downplay criticism of the drug.
http://www.cbc.ca/story/business/national/2004/11/01/merck_041101.html   (255 words)

  
 Merck Careers
Our guides are here to tell you about exciting Merck opportunities for both experienced hires and recent graduates, our culture and more.
You’ll get a glimpse into our everyday world here at Merck and see how you could help people live healthier lives.
Here at Merck, we rally around the statement made in 1950 by George W. Merck, the son of our founder, - "We try never to forget that medicine is for the people.
http://www.merck.com/careers   (96 words)

  
 Merck Institute for Science Education
Within the Partnership, Merck promotes systemic reform and attempts to build the districts' capacity for effecting and sustaining meaningful change.
It seeks to achieve this goal through a systemic approach: by building local capacity, by enhancing the knowledge and skills of the teaching staff, by introducing effective curricula and instructional materials, by building systems of support for instructional improvement, and by aligning policy around this vision of science education.
The primary goal of the Merck Institute for Science Education is to provide all children with strong, inquiry-centered instruction that meets the emerging national standards in science, thereby raising levels of student performance.
http://www.nas.edu/rise/examp67.htm   (1097 words)

  
 Human Life International - Merck Boycott - Merck Meeting 2004
We are even more distressed that this same pattern of human rights violations continues to take place with the PER-C6 cell line that Merck has taken license for in developing a new AIDS vaccine.
As stockholders in Merck we are particularly distressed at the violation of human rights that occurred in the early 1960s in the development of two cell lines, the RA 27/3 and the WI-38, which were used to create the MMR vaccine.
Each of these three cell lines was developed using tissue taken from children who were aborted.
http://www.hli.org/merck_merck_meeting2004.html   (542 words)

  
 Merck Faces U.S. Investigation Regarding Its Painkiller Vioxx
For years, even as evidence mounted that the medicine might increase the risk of heart attacks, Merck disputed such findings.
Merck did not say what the investigations were about and federal agencies do not as a rule comment on such investigations.
The Justice Department investigation could be looking at that issue as well as whether Merck misled regulators or perhaps caused Medicare to pay for the prescription drug when its use was not warranted.
http://www-tech.mit.edu/V124/N52/52_long3.52w.html   (311 words)

  
 Veterinary Research Programs - National Web SIte
Merck Merial Veterinary Student and Graduate Internship Programs
NIH T32 Research Training Grants for Post-Graduate Veterinarians
Second Annual Merck Merial Veterinary Research Award for Graduate Veterinians
http://cvm.msu.edu/ORG/rgs/nationalwebsite.htm   (70 words)

  
 Forbes.com: Street Fight: Merck
One in four Americans receive their prescription medicines from Medco's drug distribution channels.
We do not believe that cardiovascular complications will lead to any change in the prescriptions of Vioxx.
Based on a recent study we did with more than 100 cardiologists, the cholesterol-lowering drug market will grow 12.5%, to $27 billion, in 2005.
http://www.forbes.com/2001/06/25/0625streetfight.html   (841 words)

  
 The Merck Publishing Group
Coverage of traditional medicines, nutraceuticals, and cosmeceuticals has been enhanced.
The Merck Manual of Diagnosis and Therapy, Seventeenth Edition has set the standard for excellence in professional medical information since it was first published in 1899.
The Merck Manual of Health and Aging is the comprehensive guide to the changes and challenges of aging — for older adults and those who care for and about them.
http://www.merckbooks.com   (318 words)

  
 Merck Online Thailand
Moreover, this challenging project further demonstrates -Merck's commitment to -environmental and social responsibilities.
Thus, the company lives up to, and is aware of, customer service and responsible care.
Chemicals are stored in 14 different zones, not only in accordance to Thai standards -- but also in line with standards developed by the Association of the Chemical Industry in Germany (VCI), in line with German regulations for hazardous substances.
http://www.merck.co.th/en/about/social_make_tour.asp   (382 words)

  
 Merck & Co., Inc. - Company profile & brands
Documents Suggest Merck Tried to Censor Vioxx Critics
But when Singh became concerned about a 2000 study suggesting Vioxx increased the risk of heart attacks, Merck tracked Singh's public comments on Vioxx, eventually contacting his bosses at Stanford and hinting "there would be repercussions...
Merck hired Stanford University's Dr. Gurkirpal Singh in 1998 and paid him up to $2,500 for each talk he gave to other physicians about Vioxx.
http://www.transnationale.org/fiches/69.htm   (608 words)

  
 Neuroland index
Online medical journals:: Archives of Neurology, Neurology, PubMed, American Family Physician, Postgraduate Medicine, BMJ, Annals of Int Med, NEJM, MD Consult, Med Reviews in neurological diseases, MD Net Guide
Online books: Merck Manual of Diagnosis and Therapy, Neurological disorders, Psychiatric disorders, emedicine Neurology, Medscape, Medlink by Athena diagnostics
Merck Medicus on line - registration required for US licensed physicians.
http://neuroland.com/default_old.htm   (374 words)

  
 Merck - South Africa
Merck KGaA brings new hope to colorectal cancer patients
Merck KGaA has announced that the Swiss Agency for Therapeutic Products (Swissmedic) has approved the use of Erbitux (cetuximab) for the treatment of patients with colorectal cancer who no longer respond to standard chemotherapy treatment with irinotecan.
Merck (Pty) Ltd is proud to announce the launch of Glucovance®, the first oral antidiabetic that offers type 2 diabetic patients the best of both worlds in a single tablet.
http://www.merck.co.za/home.asp?pid=732   (349 words)

  
 Merck
Merck manufacturing managers recognized that the lack of efficiency in the CNC programming process was becoming a major problem.
In many countries Merck is one of the major suppliers in the generic drug industry thanks to its ability to bring these drugs to market quickly.
The ethical line, which includes patented drugs developed or licensed by the company, includes cardiovascular agents, drugs for treating metabolic diseases and thyroid diseases, corticosteroids, antibiotics and antiallergics.
http://www.dptechnology.com/Success_Stories/Merck/Merck.htm   (1525 words)

  
 BW Online November 13, 2003 Merck's Downer Keeps Deepening
The drug, called Emend, failed to ease the illness' symptoms in a late-stage clinical trial, the company says.
Emend, by contrast, controls a protein believed to be linked to emotions and stress.
Merck (MRK) already sells Emend as a treatment for nausea caused by chemotherapy, but approval to market it as a depression remedy would have transformed it from a niche product to a potential $1 billion-a-year blockbuster.
http://www.businessweek.com/technology/content/nov2003/tc20031113_9818_tc119.htm   (764 words)

  
 Merck & Co., Inc., - Investment Prospectus
The Company's products include therapeutic and preventive agents, generally sold by prescription, for the treatment of human disorders.
Merck determines the source or sources of shares used to fulfill Plan requirements and, subject to certain regulatory restrictions on the frequency with which it can change its determination, may change such determination from time to time without notice to Plan participants.
Merck may suspend, modify or terminate the Plan at any time in whole or in part or with respect to participants in certain jurisdictions.
http://www.wellsfargo.com/com/shareowner_services/services_for_shareholders/investment_plan/merck.jhtml?rld   (6609 words)

  
 Merck pulls Vioxx across the globe - Stocks & Economy - MSNBC.com
Vioxx was used in the colon cancer trial because some researchers theorize that inflammation, present in arthritis, may be linked to colon cancer.
“Patients who are currently taking Vioxx should contact their health care providers to discuss discontinuing use of Vioxx and possible alternative treatments,” Merck said.
“Given the availability of alternative therapies, and the questions raised by the data, we concluded that a voluntary withdrawal (of Vioxx) is the responsible course to take,” Merck chief Gilmartin said.
http://www.msnbc.msn.com/id/6139592   (880 words)

  
 Merck Sharp & Dohme - The Neuroscience Research Centre
Merck Sharp and Dohme - The Neuroscience Research Centre
http://www.msd-nrc.co.uk   (9 words)

  
 Vioxx Advisor
Top Merck researcher says many studies proved Vioxx safe
Merck researcher defends Vioxx test results at trial
Vioxx trial: Doc says drug did not cause heart attack
http://www.vioxxadvisor.com   (294 words)

  
 MerckMedicus : Mobile MerckMedicus
Merck & Co., Inc. does not endorse and is not responsible for the accuracy of the content, or for the practices or standards of non-Merck sources.
This information has been developed and provided by an independent third-party source.
To help you work more efficiently with your personal digital assistant (PDA), MerckMedicus is excited to provide you with several options to use an integrated set of useful medical resources for your PDA.
http://www.merckmedicus.com/pp/us/hcp/hcp_mobile_medicus.jsp   (191 words)

  
 UNCF/MERCK Home page
Our joint Science Initiative is an innovative approach that will create new opportunities in the life and physical sciences and develop a huge, untapped resource for America.
The College Fund/UNCF and The Merck Company Foundation have established scholarship awards for outstanding African American students pursuing studies and careers in the field of biomedical research.
At least 37 awards will be given annually--15 at the undergraduate level, 12 at the graduate level, and 10 at the postdoctoral level.
http://www.uncf.org/merck   (157 words)

  
 Merck Veterinary Manual
The Merck Veterinary Manual (MVM) has served veterinarians and other animal health professionals as a concise and reliable animal health reference for over 45 years.
The Merck Veterinary Manual Online is published on a nonprofit basis through a cooperative effort of Merck & Co, Inc. and Merial Limited as a free service to the veterinary profession.
http://www.merckvetmanual.com/mvm/index.jsp   (56 words)

  
 Health And Medicine
Merck Manual (www.merck.com/pubs/mmanual/) Merck Manual of Diagnosis and Treatment in medical terms.
Merck Manual - Home Edition (www.merck.com/pubs/mmanual_home/) Merck Manual of Diagnosis and Treatment in everyday language.
MedWeb (www.medweb.emory.edu/medweb/) Formerly Emory MedWeb, this new site of Emory University Health Sciences Center Library has a keyword-searchable database and provides a host of links to other sites.
http://www.elizpl.org/health_and_medicine.htm   (857 words)

  
 Fool.com: Merck in the Balance [Motley Fool Take] January 27, 2004
The question is how the second-largest U.S. drug maker will replace Zocor's $5 billion in annual sales when the drug comes off patent in 2006.
If nothing else, there doesn't seem to be a whole lot of risk baked in at these levels.
This morning, the drug maker reported sharply lower fourth-quarter profits, citing restructuring costs, lower sales of a key drug, and a new U.S. wholesaler distribution program among the culprits.
http://www.fool.com/News/mft/2004/mft04012722.htm   (301 words)

  
 Merck KGaA - Fiscal Year 2000
The Merck Group has seen significant changes in management and organization in 2000.
Merck Eurolab: Leading Full-Service Provider for Laboratories in Europe
Cosmetics, Health, Nutrition: Continued Growth with Health and Beauty
http://www.onkologie.merck.de/servlet/PB/menu/1074940_pcontent/content.html   (112 words)

  
 Health Illustrated Encyclopedia
Please discuss any and all treatment options with your healthcare professional.
Merck and Co., Inc. is not responsible for this content.
The manufacturer of a product generally has the most complete information about that product.
http://www.mercksource.com/pp/us/cns/cns_hl_adam.jspzQzpgzEzzSzppdocszSzuszSzcnszSzcontentzSzadamzSzencyzSzarticlezSzindexzPzhtm   (95 words)

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