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Topic: Malignant melanoma



  
 Malignant melanoma - Wikipedia, the free encyclopedia
Radiation therapy is often used after surgical resection for patients with locally or regionally advanced melanoma or for patients with unresectable distant metastases.
Treatment of malignant melanoma is best performed from a multidisciplinary approach including dermatologists, medical oncologists, radiation oncologists, surgical oncologists, general surgeons, neurologists, neurosurgeons, otorynolaryngologists, radiologists, pathologists/dermatopathologists, research scientists, nurse practitioners and physician assistants, and palliative care experts.
In research setting other therapies, such as gene therapy, may be tested.
http://en.wikipedia.org/wiki/Malignant_melanoma   (2351 words)

  
 Melanoma
Melanoma is one of the deadliest skin cancers but with increasing awareness, it can be cured in its earliest stage.
Eleven patients, all female, with a mean age of 40 years (range, 8-83 years), presented with pigmented lesions clinically suspected to be malignant melanoma or atypical melanocytic nevi affecting the vulva (7 patients), perineum (3 patients), or chest (1 patient).
Blockade of the Fas-triggered intracellular signaling pathway in human melanomas is circumvented by cytotoxic lymphocytes.
http://www.thedoctorsdoctor.com/diseases/melanoma_disease.htm   (13640 words)

  
 eMedicine - Malignant Melanoma : Article by Wendy Brick, MD
DOC for adjuvant therapy in patients with high-risk melanoma.
A malignant melanoma developing in healthy skin is said to arise de novo, without evidence of a precursor lesion.
A patient with a suggestive lesion should be referred to a dermatologist or surgical oncologist for excisional biopsy.
http://www.emedicine.com/med/topic1386.htm   (5010 words)

  
 Malignant Melanoma
Melanoma is the third most common skin cancer and represents from 3% to 5% of cutaneous malignancies.
The lack of differentiation may be responsible for the aggressive behavior of amelanotic melanomas; 75% of which have already metastasized at the time of presentation.
Clark, W.H., Jr.: A classifiation of malignant melanoma in man correlated with histogenesis and biologic behavior.
http://www.dentalcare.com/soap/intermed/melan.htm   (3898 words)

  
 Malignant melanoma
Malignant melanoma may arise in the skin anywhere on the body.
Malignant melanoma is locally staged based on the depth of penetration through the skin and its appendages.
As of early 2003, some researchers think there may be two pathways to malignant melanoma, one involving exposure to sunlight and the other with melanocyte proliferation triggered by other factors.
http://www.healthatoz.com/healthatoz/Atoz/ency/malignant_melanoma.jsp   (3959 words)

  
 eMedicine - Malignant Melanoma : Article by Susan M Swetter, MD
Kirkwood JM: Adjuvant IFN alpha2 therapy of melanoma.
However, individuals with numerous moles (common or dysplastic) or a family history of melanoma should be educated regarding the importance of skin self-examination for early detection of skin cancer.
Melanoma can occur on any skin or mucosal surface, although a history of cutaneous melanoma does not appear to increase the risk of developing primary intraocular or mucosal melanoma.
http://www.emedicine.com/derm/topic257.htm   (7476 words)

  
 malignant melanoma
This is referred to as the "radial" growth phase of melanoma and is clinically macular or only slightly elevated.
Unfortunately the incicence of this disease appears to be increasing, such that currently about 1 in 100 persons in the United States can expect to develop this cancer in a lifetime.
The cancer presumably begins at one focus in the skin at the dermo-epidermal junction.
http://matrix.ucdavis.edu/tumors/tradition/melanoma.html   (290 words)

  
 Melanoma
For melanoma, pictures may be taken of the chest, abdomen, and pelvis.
Surgery or radiation therapy as palliative therapy to relieve symptoms and improve quality of life.
In men, melanoma is often found on the trunk (the area from the shoulders to the hips) or the head and neck.
http://www.meb.uni-bonn.de/cancer.gov/CDR0000062713.html   (3307 words)

  
 malignant melanoma
Current research in melanoma is focused on finding effective systemic therapy.
DTIC therapy is associated with a response rate of 15 to 25%, with only 5% of patients achieving a complete response.
The advocates of this method point out correctly that surgery is the only effective therapy for regional lymph node disease; moreover, in several retrospective studies, a survival advantage of as much as 25% has been demonstrated in patients with clinically negative but pathologically positive lymph nodes.
http://www.cancernews.com/articles/melanomas.htm   (1405 words)

  
 National Cancer Institute - What You Need To Know About Melanoma
Melanomas arising in areas other than the skin (such as intraocular melanoma, which is melanoma arising in the eye) are not discussed here.
This booklet is about melanoma of the skin.
National Cancer Institute - What You Need To Know About Melanoma
http://www.cancer.gov/cancerinfo/wyntk/melanoma   (380 words)

  
 Melanoma — Complete medical information regarding skin cancer on MedicineNet.com
To understand melanoma, it is helpful to know about the skin and about melanocytes, what they do, how they grow, and what happens when they become cancerous.
In men, it is often found on the trunk (the area from the shoulders to the hips) or the head and neck.
Questions To Ask Before Surgery - Surgery questions to ask prior to having a procedure are important.
http://www.medicinenet.com/melanoma/article.htm   (668 words)

  
 Melanoma Patients' Information Page
Electric pulse drug delivery system effective in cutaneous malignancies
Providing the support and information you need to be a proactive participant in your treatment decisions.
Ultrasound Detects Melanoma Metastases Missed by Clinical Examination
http://www.mpip.org   (476 words)

  
 Malignant Melanoma
Wide surgical resection is imperative for malignant melanoma.
Suspect melanoma when any skin lesion or nevus (a circumscribed stable
Melanoma spreads through the lymphatic and vascular systems and metastasizes to
http://www.med-help.net/MalignantMelanoma.html   (513 words)

  
 Disease Category Listing (196): Malignant Melanoma
A clinical study evaluating the efficacy, safety, and tolerability of a study drug in subjects with advanced melanoma.
A clinical study comparing standard treatment for advanced melanoma to an experimental study drug.
SWOG E4697: A Randomized, Placebo-Controlled Phase III Trial of Yeast Derived GM-CSF Versus Peptide Vaccination Versus GM-CSF Plus Peptide Vaccination Versus Placebo in Patients with No Evidence of Disease After Complete Surgical Resection of Locally Advanced and/or Stage IV Melanoma
http://www.centerwatch.com/patient/studies/cat196.html   (5321 words)

  
 MedlinePlus: Melanoma
NCI Researchers Confirm the Effectiveness of Immunotherapy Approach to Treating Melanoma (03/31/2005, National Cancer Institute)
Melanoma: A Kind of Skin Cancer (American Academy of Family Physicians)
Melanoma (Mayo Foundation for Medical Education and Research)
http://www.nlm.nih.gov/medlineplus/melanoma.html   (281 words)

  
 MedlinePlus Medical Encyclopedia: Skin cancer
Complexion - Skin cancers are more common in people with light-colored skin, hair, and eyes.
Genetics - Having a family history of melanoma increases the risk of developing this cancer.
Basal cell carcinoma and squamous cell carcinoma are the most common nonmelanoma skin cancers.
http://www.nlm.nih.gov/medlineplus/ency/article/001442.htm   (729 words)

  
 malignant melanoma - OneLook Dictionary Search
noun: any of several malignant neoplasms (usually of the skin) consisting of melanocytes
Malignant melanoma, Melanoma, malignant : MedTerms.com Medical Dictionary [home, info]
Phrases that include malignant melanoma: malignant melanoma in situ, malignant melanoma - choroid, malignant melanoma - eye, malignant melanoma choroid, superficial spreading malignant melanoma
http://www.onelook.com/?w=malignant+melanoma&ls=a   (172 words)

  
 MIR Teaching file case ga003
This patient is a 45 year old man with a history of metastatic melanoma.
The patient underwent wide excision, without lymph node dissection.
Nodular melanoma is generally considered the most lethal.
http://gamma.wustl.edu/ga003te143.html   (398 words)

  
 Gallery of Melanoma
The following images (about 30, each initially presented in thumbnail sketch form) are provided to illustrate the diagnostic features.
Melanoma is classified according to the histologic types.
http://matrix.ucdavis.edu/tumors/tradition/gallery-melanoma.html   (35 words)

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