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| | ISMRD - Galactosialidosis |
 | | For some lysosomal storage diseases, bone marrow transplant has been trialed as an experimental therapy, but there are no conclusive results on the long-term benefits. |  | | These molecules are continuously made and broken down in our bodies and this process is necessary for appropriate mental and physical development. |  | | Additionally, some trials have been performed with Pamidronate, a drug that helps to increase bone strength. |
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http://www.mannosidosis.org/development/mucolipidosisII.htm
(1062 words)
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| | Drug Inhibition of Gly-Sar Uptake and hPepT1 Localization using hPepT1-GFP Fusion Protein |
 | | These results suggest that hPepT1-GFP does not seem to be functional in lysosome or early endosome; rather, it might be internalized into lysosome for degradation. |  | | Yet there has been no direct evidence to suggest which transporter is responsible for the peptide uptake activity in the lysosome. |  | | Therefore, PMA was also used in our experiment. |
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http://www.aapspharmsci.org/view.asp?art=ps030102
(3604 words)
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| | The Role of Intraorganellar Ca2+ in Late Endosome-Lysosome Heterotypic Fusion and in the Reformation of Lysosomes from ... |
 | | Bright, N.A., Reaves, B.J., Mullock, B.M., Luzio, J.P. Dense core lysosomes can fuse with late endosomes and are re-formed from the resultant hybrid organelles. |  | | Data are presented as mean ± SEM of three experiments. |  | | Mullock, B.M., Perez, J.H., Kuwana, T., Gray, S.R., Luzio, J.P. Lysosomes can fuse with a late endosomal compartment in a cell-free system from rat liver. |
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http://www.jcb.org/cgi/content/full/149/5/1053
(6854 words)
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| | Meaning of cialis,nitrous oxide,rapid eye movement,bug,Fahrenheit,primary lysosome,portal ... |
 | | A primary lysosome becomes a secondary lysosome when it fuses with vesicles that contain matter to be ingested. |  | | Explanation of cialis, nitrous oxide, rapid eye movement, bug, Fahrenheit, primary lysosome, portal vein, psychologist, ion, sarcomere |  | | Meanings of cialis, nitrous oxide, rapid eye movement, bug, Fahrenheit, primary lysosome, portal vein, psychologist, ion, sarcomere |
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http://www.english-test.net/pcat/vocabulary/meanings/053/pcat-words.php
(1003 words)
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| | Amino Acid Autobiography @ NaturalResearch.org (Natural Research) |
 | | In even slightly acidic conditions protonation of the nitrogen occurs, changing the properties of histidine and the polypeptide as a whole. |  | | It is used by many proteins as a regulatory mechanism, changing the conformation and behavior of the polypeptide in acidic regions such as the late endosome or lysosome, enforcing conformation change in enzymes. |
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http://www.naturalresearch.org/encyclopedia/Amino_acid
(1669 words)
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| | Lysosomes and Peroxisomes |
 | | It moves away to fuse with a developing lysosome (such as the vacuoles seen in the previous figure). |  | | Then, vesicles carrying lysosomal enzymes fuse with the vesicle and the vacuole becomes an active secondary lysosome. |  | | This change can be detected if you link a ligand to fluorescein. |
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http://cellbio.utmb.edu/cellbio/lysosome.htm
(722 words)
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| | Lysosome Page |
 | | In this process, an old or damages organelle are enveloped by endosomes and then fused to lysosomes. |  | | Each lysosome is surrounded by its own membrane due to the acidic conditions within it. |  | | The lysosome then fuses with the membrane of the endosome and begins to break down the macromolecule. |
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http://sun.menloschool.org/~cweaver/cells/e/lysosomes
(323 words)
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| | Lysosomal Storage Disease Introduction |
 | | review lysosomal function and associated pathways, look at what happens when there are defects in lysosomal function and analyze some of the diseases associated with lysosomal defects. |  | | Some human diseases are caused by lysosome enzyme disorders. |  | | We'll finish up the module with a case study that will show how a particular lysosomal storage disease manifests clinically. |
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http://cats.med.uvm.edu/cats_teachingmod/microbiology/courses/lysosomal_storage_disease/intro/1_1_lys_intro2.html
(226 words)
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| | Untitled Document |
 | | This vesicle fuses with a primary lysosome forming a secondary lysosome. |  | | Indeed, an interuption of this process can lead to a disease condition such as Tay Sach's disease. |  | | The term hetero (different) phagy (to eat) refers to a process whereby lysosmes aid in the intracellular digestion of material gathered from outside of the cell by some kind of endocytotic mechanism. |
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http://academic.brooklyn.cuny.edu/biology/bio4fv/page/lyscomb.htm
(395 words)
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| | Animal Cell Lysosomes |
 | | Lysosme recognizes food vacuoles and fuses with them creating one package surrounded by the lysosome membrane. |  | | The digestive enzymes that work in the lysosomes are only active in an acidic condition. |  | | This is n image of the process of digestion the lysosome does. |
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http://sun.menloschool.org/~birchler/cells/animals/lysosome
(384 words)
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| | Chapter 13 Outline |
 | | Pinocytotic vesicles enter early endosomes F. Three pathways to the lysosome 1. |  | | (self destruction) In some cases lysosomes are utilized to eliminate cells in otherwise healthy organisms. |  | | Autophagic vacuoles and the autophagosome Sometimes called "suicide bags" because of their role in self digestion and often self destruction of the cell itself by these structure. |
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http://geowww.geo.tcu.edu/bio/couch/Biology3603/Ch13lect.html
(732 words)
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| | illustration of cell structure: lysosome by Russell Kightley Media |
 | | Please see all of our pictures at our |  | | Prions (the rogue proteins associated with Mad Cow Disease) are resistant to degradation by lysosomal enzymes and so accumulate in the cell. |  | | illustration of cell structure: lysosome by Russell Kightley Media |
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http://www.rkm.com.au/CELL/organelles/lysosome.html
(133 words)
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| | Lysosome - Wikipedia, the free encyclopedia |
 | | There are a number of illnesses that are caused by the malfunction of the lysosomes or one of their digestive proteins, e.g., Tay-Sachs disease, or Pompe's disease. |  | | The lysosome itself is likely safe from enzymatic action due to having proteins in the inner membrane which has a three-dimensional molecular structure that protects vulnerable bonds from enzymatic attack |  | | The digestive enzymes need the acidic environment of the lysosome to function correctly. |
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http://en.wikipedia.org/wiki/Lysosome
(380 words)
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| | Lysosome Biogenesis in C. elegans |
 | | A basic understanding of the cellular mechanisms that control these processes is important since changes in lysosome function and morphology have been correlated with a variety of human diseases including Alzheimers and cancer. |  | | To understand how lysosome assembly and stability are controlled in the cells of multicellular animals we are identifying and characterizing the genes and pathways that govern lysosome assembly and maintenance in the intestine of the model multicellular animal, Caenorhabditis elegans. |  | | Rab proteins are important regulators of vesicular transport and trafficking in the secretory and endocytic pathways. |
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http://www.lclark.edu/dept/biochem/elegans.html
(333 words)
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| | Lysosomes and Peroxisomes |
 | | Lysosomal storage diseases are caused by the accumulation of macromolecules (proteins, polysaccharides, lipids) in the lysosomes because of a genetic failure to manufacture an enzyme needed for their breakdown. |  | | This reduces the risk of their digesting their own cell if they should escape from the lysosome. |  | | At one time, it was thought that lysosomes were responsible for killing cells scheduled to be removed from a tissue; for example, the resorption of its tail as the tadpole metamorphoses into a frog. |
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http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/L/Lysosomes.html
(809 words)
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| | LYSISO1 Lysosome Isolation Kit |
 | | Lysosomes may also be involved in other cellular processes such as Albinism and aging. |  | | Lysosomes also contain lipases, nucleases and polysaccharidases and deficiencies in some of these enzymes lead to specific lysosomal storage diseases such as Tay Sachs, Gaucher, Hunter disease and others. |  | | Malfunctions in this organelle directly impact cell behavior and fate. |
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http://www.sigmaaldrich.com/catalog/search/ProductDetail?ProdNo=LYSISO1&Brand=SIGMA
(264 words)
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| | Australian blue rats: a hypothesis |
 | | The beige mutation in rats is thought to be an analogue of Chediak-Higashi syndrome in humans. |  | | Lysosomal ceroid storage problems may cause pulmonary fibrosis (scarring of the lungs), inflammatory bowel disease (includes diarrhea, weight loss etc.), and kidney disease. |  | | There are several different types of Hermansky-Pudlak syndrome, associated with different gene loci in humans: HPS1 plays a role in biogenesis of lysosome-related organelles, and ADTB3A mediates trafficking of membrane proteins to lysosome-related organelles. |
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http://www.ratbehavior.org/AustralianBlue.htm
(3187 words)
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| | Lysosome |
 | | Malfunction of lysosomes in humans can cause Tay-Sachs disease. |  | | Inside the lysosome, a normal pH level of 4.8 makes them remarkably effective at selectively dissolving organic substances into their component parts. |  | | This environment is separated from the cytosol by a single membrane; if this membrane is damaged, the lysosome will not function properly, but its cell can survive. |
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http://www.iscid.org/encyclopedia/Lysosome
(239 words)
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| | Lysosome - Search Results - MSN Encarta |
 | | A relatively simple gene and a lysosome, a simple part of most living cells, were also created in the laboratory for the first time. |  | | A new element discovered this year soon became the subject of controversy when both American and Soviet scientists claimed to have synthesized it first. |  | | Lysosome, membrane-bound sac found in nucleated cells that contains digestive enzymes that break down complex molecules in the body. |
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http://ca.encarta.msn.com/Lysosome.html
(131 words)
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| | LAMP2 antibody - Lysosome Marker (ab2929) datasheet |
 | | Membrane-associated glycoproteins have an important role in normal lysosomal function. |  | | Lysosomes are membrane-bound vacuoles which play a critical role in cellular metabolism. |  | | But please do contact us if you would like any reassurance! |
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http://www.abcam.com/?datasheet=2929
(550 words)
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| | Fiesta Mundo: LYSOSOME Artist Space |
 | | Illegal use of any media found in this site is subject to legal action. |  | | Lysosome, a biological term also known as the "suicidal bag of cells". |  | | It breaks down or sacrifice for the benefit of our body and prevents us from harmful invaders such as cell debris. |
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http://www.fiestamundo.com/lysosome
(85 words)
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| | Lysosomes |
 | | When a cell needs to digest food, the lysosome membrane fuses with the membrane of a food vacuole and squirts the enzymes inside. |  | | There are times when cells do need to digest themselves. |  | | Lysosomes are formed when the Golgi complex packages up an especially large vessicle of digestive enzyme proteins. |
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http://projects.edtech.sandi.net/miramesa/Organelles/lyso.html
(135 words)
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| | lysosome |
 | | The proteasome is an organelle similar to the lysosome, which is also involved in enzymatic degradation of cellular substances. |  | | ...occur when lysosomes lack the enzymes they need to perform their recycling tasks, leading to abnormal accumulation of the molecules the lysosome is supposed to... |  | | An ionic pore forms that triggers uncontrolled osmotic swelling of the lysosome and leads to trypanosome lysis. |
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http://www.mongabay.com/igapo/biotech/lysosome.html
(372 words)
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| | MECHANISMS OF ENDOSOME TO LYSOSOME TRANSPORT IN YEAST |
 | | Defects in proper maintenance of specific organellar protein transport are the basis for many human diseases such as cancer and Alzheimer's syndrome. |  | | This putative complexity would give the yeast vacuolar system even more similarity to the lysosomal system of mammalian cells. |  | | Studies that combine genetic, molecular, and biochemical approaches will lead to the complete understanding of this intercompartmental protein transport problem. |
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http://research.uth.tmc.edu/nih/Vida.htm
(407 words)
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| | Immune system - Wikipedia, the free encyclopedia |
 | | Finally, the bacterium is digested by the enzymes in the lysosome, involving reactive oxygen species and proteases. |  | | In addition, anti-microbial proteins may be activated if a pathogen passes through the barrier offered by skin. |
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http://en.wikipedia.org/wiki/Immune_system
(2498 words)
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| | Cell Organelles: Lysosomes, Peroxisomes, Secretory Vesicles |
 | | Uncontrolled release of lysosome contents into the cytoplasm can also cause cell death (necrosis). |  | | : Lysosomes (common in animal cells but rare in plant cells) contain hydrolytic enzymes necessary for intracellular digestion. |  | | In white blood cells that eat bacteria, lysosome contents are carefully released into the vacuole around the bacteria and serve to kill and digest those bacteria. |
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http://www.cellsalive.com/cells/lysosome.htm
(136 words)
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| | secondary lysosome - OneLook Dictionary Search |
 | | secondary lysosome : The On-line Medical Dictionary [home, info] |  | | We found 2 dictionaries with English definitions that include the word secondary lysosome: |  | | Tip: Click on the first link on a line below to go directly to a page where "secondary lysosome" is defined. |
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http://www.onelook.com/?w=secondary+lysosome
(71 words)
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| | The Lysosome |
 | | The lysosome is involved in digestive activities, including breaking down large food molecules into smaller ones and the digestion of old cell parts. |  | | The lysosome is a small, round structure common in animal cells, but not usually found in plant cells. |  | | Use your Browser's back button to return to the page you were just at. |
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http://www.usoe.k12.ut.us/curr/science/sciber00/7th/cells/sciber/lysosom.htm
(75 words)
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| | 1.7g Cell Net.alfa18 : lysosome |
 | | lysosome - a spherical membrane-bound vesicle containing digestive enzymes that are released when lysosome is ruptured |  | | A text summary of the clickable map above, meant for web-crawlers and other automatic tools: |
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http://www.biologylessons.sdsu.edu/classes/lab7/semnet/lysosome.htm
(31 words)
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| | Cell |
 | | Lysosome: intracellular organelle able to absorb solid particles from the surrounding area. |  | | Centrioles: ponticulus at the centre of a centrosome. |
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http://www.infovisual.info/03/001_en.html
(172 words)
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| | Holistic Health Encyclopedia - O |
 | | a specialized cellular part (as a mitochondrion, lysosome, or ribosome) that is analogous to an organ. |
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http://www.myholistic.com/glossary/O.php3
(1802 words)
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| | Lysosome associated membrane protein 1 |
 | | Please send any questions or comments about the Human Protein Reference Database to help |  | | You are at: Home » Proteins » Lysosome associated membrane protein 1 |
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http://www.hprd.org/protein/01076
(36 words)
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| | Identifont - Lysosome |
 | | Information about the typeface Lysosome and where to buy it. |
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http://www.identifont.com/show?54F
(24 words)
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| | www.myspace.com/lysosome |
 | | if you want to add lysosome @ Friendster this is our email add lysosome_incubus@yahoo.com or lysosome_band@yahoo.com here on Myspace !!!!!! |  | | Add us up folks & listen to our crappy shit! |  | | Lysosome's Latest Blog Entry [Subscribe to this Blog] |
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http://profile.myspace.com/index.cfm?fuseaction=user.viewprofile&friendID=32355991&Mytoken=FD4D34BD-98FC-C036-E42BD20330DAFFD727660724
(170 words)
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| | Lysosome - Glossary Entry - Genetics Home Reference |
 | | Lysosome - Glossary Entry - Genetics Home Reference |  | | A sac-like compartment inside a cell that has enzymes that can break down cellular components that need to be destroyed. |
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http://ghr.nlm.nih.gov/ghr/glossary/lysosome
(56 words)
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| | Lysosome : Definition |
 | | Search for Lysosome in these other databases too |  | | A membrane- enclosed bag of hydrolytic enzymes found in the cytoplasm of eukaryotic cells. |
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http://www.everythingbio.com/glos/definition.php?word=Lysosome
(113 words)
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