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| | A novel lipid-anchored A-kinase Anchoring Protein facilitates cAMP-responsive membrane events -- Fraser et al. 17 (8): ... |
 | | Four additional AKAP18 mutants were constructed to determine if acylation of a particular residue was more significant than | | | Immunocytochemical analysis was carried out using polyclonal antibodies raised against recombinant AKAP18 (red) and rat RII | | | Nauert, J.B., Klauck, T.M., Langeberg, L.K. and Scott, J.D. Gravin, an autoantigen recognized by serum from myasthenia gravis patients, is a kinase scaffold protein. |
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http://embojournal.npgjournals.com/cgi/content/full/17/8/2261
(8024 words)
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| | Resumé |
| | A highly multidisciplinary approach has been adopted in the study of lipids in model and natural membranes which began with graduate work on liposomal and model systems (Leeds, 1972 - 1975), then post-doctoral research into the study of the molecular specificity of lipid-protein in membranes by ESR spin-label methods (Germany, 1976 - 1980). | | | Other activities include resolution of new membrane protein reconstitutions and functional characterizations in bilayers, the development and extensive use of novel solid state NMR and spin-label ESR methods to study protein structure and lipid-protein specificity in natural and reconstituted, fully functional membranes. | | | Since returning to a faculty position in Oxford (1980), a very wide range of membrane systems and biophysical approaches, including novel solid state NMR methods, have been applied to the study of both lipids and proteins in model and fully functional natural membranes. |
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http://www2.bioch.ox.ac.uk/~awatts/resume.html
(588 words)
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| | GPI Modification Site Prediction |
| | Otherwise, interpret the result in your experimental context... | | | Sequence analysis of GPI-anchored proteins on the proprotein level | | | Please, verify the biological context of your query protein, whether this condition is fulfilled in your case. |
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http://mendel.imp.univie.ac.at/sat/gpi/gpi_server.html
(223 words)
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| | Prediction of lipid posttranslational modifications and localization signals from protein sequences: big-{Pi}, NMT and ... |
| | Research Institute of Molecular Pathology, Dr. Bohr-Gasse 7, A-1030 Vienna, Republic of Austria | | | In this case, no deviation for the physical property pattern was measured although the protein is not part of the learning set. | | | Cserzo,M., Eisenhaber,F., Eisenhaber,B. and Simon,I. (2002) On filtering false positive transmembrane protein predictions. |
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http://nar.oxfordjournals.org/cgi/content/full/31/13/3631
(2053 words)
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| | February 23, 1995 |
| | impact of structure of fluidity: predictions based on bilayer model are borne out by structural changes in lipid structures: | | | e.g., gramicidin S: an antibiotic ionophore (where ionophore is defined as a lipid soluble structure that facilitates ion-transport across a membrane) | | | lipid bilayer with polar "head" groups at surface and hydrophobic "tails" internal |
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http://www.uky.edu/Classes/BCH/401/Watt/Chapter12/chapter12.htm
(380 words)
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| | [No title] |
| | Gp70 is one of two proteins found concentrated in crystalline bodies (3) that are associated with the detergent-insoluble cytoskeleton (1). | | | More recently, we are using molecular genetic and cytological techniques to address the function of specific proteins that we have identified. | | | The signals responsible for the localized actin recruitment and subsequent dissolution are actively studied by many laboratories. |
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http://bsweb.unl.edu/faculty/chia
(677 words)
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| | GAS1 - Glycolipid anchored surface protein 1 precursor |
| | The phenotype of ggp1 null mutant expressing the mutant proteins was also analyzed to understand if this region is important for gp115 function. | | | GAS1 deletion was found to be lethal in the absence of the Bck1 and Slt2 (Mpk1) proteins of the cell integrity pathway. | | | Examination of raft association of the GPI-anchored Gas1p and plasma membrane ATPase, Pma1p, in the conditional elo3Delta erg6(ts) double mutant, revealed a specific defect of the mutant to maintain raft association of preexisting Pma1p. |
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http://www.ihop-net.org/UniPub/iHOP/gg/35444.html
(1382 words)
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| | Lipid anchored protein - Wikipedia, the free encyclopedia |
| | Prenylation is the attachment of lipid chains to proteins to facilitate their interaction with the cell membrane. | | | Other anchors include the GPI anchor (see there). | | | It is believed that the fatty acid chain inserts and assumes a place in the bilayer structure of the membrane alongside the similar fatty-acid tails of the surrounding lipid molecules. |
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http://en.wikipedia.org/wiki/Lipid_anchored_protein
(152 words)
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| | ZMBH Seminar |
| | Trafficking of lipid-anchored protein: what can we learn from the trypanosome surface coat? |
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http://www.zmbh.uni-heidelberg.de/Colloquium/Engstler_Seminar.html
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| | Lipid-Anchored Proteins |
| | Often found on proteins involved in signal transduction | | | Critical for proper protein function: location, location, location! |
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http://www.trentu.ca/chemistry/srafferty/330lec/330LEC12/tsld021.htm
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| | Delv.co.uk: anchored websites in the UK |
| | Held by an anchor; at anchor; held safely; as, an anchored bark ; also, shaped like an anchor; forked; as, an anchored tongue. | | | Delv.co.uk: anchored websites in the UK Viewing Results for "anchored" - Showing 1 - 4 | | | Compare and review products from over 1,000 UK stores at Shopzilla.co.uk. |
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http://www.michael-jackson.org.uk/jacko/anchored.html
(159 words)
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| | anchored - OneLook Dictionary Search |
| | We found 8 dictionaries with English definitions that include the word anchored: | | | Tip: Click on the first link on a line below to go directly to a page where "anchored" is defined. | | | anchored : Webster's Revised Unabridged, 1913 Edition [home, info] |
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http://www.onelook.com/?w=anchored&ls=a
(166 words)
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| | fatty acid: Definition and Much More From Answers.com |
| | Meaning #1: any of a class of aliphatic monocarboxylic acids that form part of a lipid molecule and can be derived from fat by hydrolysis | | | Note: click on a word meaning below to see its connections and related words. | | | In chemistry, especially biochemistry, a fatty acid is a carboxylic acid (or organic acid), often with a long aliphatic tail (long chains), either saturated or unsaturated. |
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http://www.answers.com/topic/fatty-acid
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| | Nuclear Import/Export |
| | must overcome significant energy barrier for lipid bilayer fusion | | | brings membranes into close apposition for lipid rearrangements | | | t-SNAREs are also family of C-terminally anchored proteins |
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http://info.bio.cmu.edu/courses/03240/LectureNotes/18VesicleFormation
(270 words)
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| | The Structure and Function of the Plasma Membrane |
| | ionic and H bond interactions with hydrophilic lipid and protein groups | | | EM shows 2 dark lines with light interior | | | Transition temperature- temperature where membrane goes from fluid to gel |
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http://www.people.memphis.edu/~clessman/LECT4CELL.HTM
(648 words)
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