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| | Facts About Limb-Girdle Muscular Dystrophy |
 | | I hope you can tell from my story that having limb-girdle muscular dystrophy doesn't mean the end of your choices or your dreams. | | | But gradually, muscular dystrophy just became a part of our lives, and we coped with it by learning all we could. | | | My family had to learn a lot about muscular dystrophy and make some major adjustments, both physical and psychological. |
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http://www.mdausa.org/publications/fa-lgmd.html
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| | Limb-Girdle Muscular Dystrophy Overview |
| | Fascioscapulohumeral muscular dystrophy (FSH), an autosomal dominant disorder, typically presents before age 20 years with marked weakness of the facial muscles and the stabilizers of the scapula or the dorsiflexors of the foot. | | | Thus, females with a negative family history who are suspected of having LGMD should first be tested for dystrophinopathy with dystrophin studies of muscle biopsy by a laboratory experienced with such testing. | | | Affected individuals remain ambulatory into their 20s, but heart failure from dilated cardiomyopathy (DCM) is a relatively frequent clinical concern. |
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http://www.geneclinics.org/profiles/lgmd-overview/details.html
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| | LATTER ONSET MUSCULAR DYSTROPHY MDs LATTER ONSET |
| | The initial muscles affected are the proximal muscles of the pelvic and shoulder girdles. | | | The use of orthopedic devices and physiotherapy, for example, can keep patients ambulatory longer, minimise crippling contractures, and prevent or delay scoliosis (curvature of the spine). | | | Extraocular muscle are involved initially and muscles used in swallowing tend to become affected. |
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http://www.mda.org.au/specific/mdalaton.html
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| | Limb-Girdle Muscular Dystrophy,lgmd,Limb-Girdle Muscular Dystrophy,lgmd |
| | LGMD is treated by physical therapy and occupational therapy, the use of assisting medical equipment, and monitoring for cardiac and respiratory complications (Questions and Answers, 2000). | | | Equipment that helps an individual move from a sitting to a standing position may be helpful because this movement requires the use of the muscles affected by LGMD. | | | The child with muscular dystrophy often cannot perform physical activities as well as his or her unaffected peers. |
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http://www.icomm.ca/geneinfo/lgmd.htm
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| | NINDS Muscular Dystrophy (MD) Information Page |
| | The NINDS supports a broad program of research on MD. The goals of these studies are to understand MD and to develop techniques to diagnose, treat, prevent, and ultimately cure muscular dystrophy. | | | There are many forms of muscular dystrophy, some noticeable at birth (congenital muscular dystrophy), others in adolescence (Becker MD), but the 3 most common types are Duchenne, facioscapulohumeral, and myotonic. | | | NINDS health-related material is provided for information purposes only and does not necessarily represent endorsement by or an official position of the National Institute of Neurological Disorders and Stroke or any other Federal agency. |
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http://www.ninds.nih.gov/health_and_medical/disorders/md.htm
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| | MedlinePlus Medical Encyclopedia: Muscular dystrophy |
| | Examination and history help to distinguish the type of MD. Specific muscle groups are affected by different types of MD. Often, there is a loss of muscle mass ( wasting), which may be disguised in some types of muscular dystrophy by an accumulation of fat and connective tissuethat makes the muscle appear larger (pseudohypertrophy). | | | Genetic counseling is advised when there is a family history of muscular dystrophy. | | | The muscles primarily affected vary, but can be around the pelvis, shoulder, face or elsewhere. |
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http://www.nlm.nih.gov/medlineplus/ency/article/001190.htm
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| | Fortnightly review: The muscular dystrophies -- Emery 317 (7164): 991 -- BMJ |
| | The quality of life of individuals with dystrophy can be much improved by a positive attitude to management which includes respiratory care, physiotherapy, and the surgical correction of contractures | | | Molecular biological techniques make the prevention of most forms of dystrophy possible through genetic counselling and prenatal | | | A molecular genetic approach seems to offer the best prospect for developing effective treatment in the future |
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http://www.bmj.com/cgi/content/full/317/7164/991
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| | Muscular Dystrophy, Limb Girdle |
| | Patients with Limb-Girdle Muscular Dystrophy may benefit from physical therapy and support and bracing of weak joints or muscles (orthotics). | | | Genetic counseling may be of benefit for patients and their families. | | | Some patients with Limb-Girdle Muscular Dystrophy may also develop: neck muscle weakness and fixed joints (contractures) in later stages of the disorder; muscles that become swollen with deposits of fat and fiber-like tissue (pseudohypertrophy); and/or severe lower back pain. |
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http://www.bchealthguide.org/kbase/nord/nord904.htm
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| | eMedicine - Limb-Girdle Muscular Dystrophy : Article by Vinod Sahgal, MD, MS |
| | Recreational Therapy: Because of the lifelong impact of LGMD, adaptations to allow avocational pursuits are essential and the role of recreational or child-life therapists is important. | | | Given the slowly progressive nature of the disease, the prudent approach to exercise therapy is to prescribe active-assistive and resistive movements and preserve and maintain muscle strength in the pelvic and shoulder girdle musculature. | | | These surgical approaches have been tried sparingly in cases of LGMD, and there are no control studies; however, in a few isolated reports, good results in the maintenance of ambulation have been reported after surgery. |
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http://www.emedicine.com/pmr/topic65.htm
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| | eMedicine - Limb-Girdle Muscular Dystrophy : Article by Glenn Lopate, MD |
| | Medicine is a constantly changing science and not all therapies are clearly established. | | | Hypertrophy of muscles, including the tongue, may be prominent. | | | Immunostaining for the specific sarcoglycan shows reduced or absent staining at the rims of the muscle fibers (see Picture 2) in the corresponding LGMD. |
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http://www.emedicine.com/neuro/topic189.htm
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| | Neuromuscular - LGD |
| | Chloride Channel (CLCN1): Myotonia congenita ; Myotonia levior | | | Severity of myopathy correlates best with level of adhalin in muscle | | | 80% of LGMD 2A patients: Some patients with only slight reductions in calpain-3 |
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http://www.neuro.wustl.edu/neuromuscular/musdist/lg.html
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| | HealthCentral - Pediatrics Encyclopedia - limb-girdle muscular dystrophy |
| | You should promptly seek professional medical care if you have any concern about your health, and you should always consult your physician before starting a fitness regimen. | | | Copyright Notice: The information provided herein should not be used for diagnosis or treatment of any medical condition. | | | The disease is progressive and may involve other muscles over a period of time. |
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http://www.healthcentral.com/peds/top/000711.cfm
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| | News Releases :: News :: UNIQUELY MANITOBA RESEARCH IDENTIFIES LIMB GIRDLE MUSCULAR DYSTROPHY GENE |
| | Collaboration with colleagues who have complementing expertise is another factor facilitating such progress. | | | Muscular dystrophy describes a group of genetic disorders that result in progressive muscle weakness caused when individual muscle cells die too soon. | | | Limb girdle muscular dystrophies are a sub-group of dystrophies characterized by loss of muscle strength in the arms and legs, with symptoms beginning in the early adult years. |
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http://myuminfo.umanitoba.ca/index.asp?sec=209&too=100&dat=2/19/2002&sta=2&wee=4&eve=8&id=957
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| | Oxford Eprints - Mutations in the fukutin-related protein gene (FKRP) identify limb girdle muscular dystrophy 2I as a ... |
| | The spectrum of LGMD2I phenotypes ranged from infants with an early presentation and a Duchenne-like disease course including cardiomyopathy, to milder phenotypes compatible with a favourable long-term outcome. | | | The limb girdle and congenital muscular dystrophies (LGMD and CMD) are characterized by skeletal muscle weakness and dystrophic muscle changes. | | | The onset of symptoms in CMD is within the first few months of life, whereas in LGMD they can occur in late childhood, adolescence or adult life. |
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http://eprints.ouls.ox.ac.uk/archive/00000282
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| | Muscular Dystrophy Campaign |
| | It has pioneered the search for treatments and cures for over 40 years and provides practical, medical and emotional support to people affected by the condition. | | | The Muscular Dystrophy Campaign is the only UK charity focusing on all muscular dystrophies and allied disorders. | | | Take a look at our Christmas cards and gifts |
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http://www.muscular-dystrophy.org/
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| | AllRefer Health - Limb-Girdle Muscular Dystrophies (Muscular Dystrophy - Limb-Girdle Type) |
| | These diseases are progressive and may involve other muscles over a period of time. | | | You are here : AllRefer.com > Health > Diseases and Conditions > Limb-Girdle Muscular Dystrophies | | | Limb-girdle muscular dystrophies include at least 10 different inherited disorders that initially affect the muscles around the shoulder girdle and the hips. |
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http://health.allrefer.com/health/limb-girdle-muscular-dystrophies-info.html
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| | European Neuro Muscular Centre - About Neuro Muscular Disorders |
| | A further focus of the meeting was to explore the different groups of proteins which are now known to be involved in limb-girdle muscular dystrophy and are known to interact with each other or work in similar pathways. | | | The identification of the way or ways that these groups of proteins may be altered to cause disease is being addressed in a variety of model systems and may in the long term provide targets for treatments. | | | Previous meetings of the consortium had discussed the identification of many of the genes and proteins involved in different types of limb-girdle muscular dystrophy and the clinical features associated with these particular disorders. |
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http://www.enmc.org/workshops/reports.cfm?p=80
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| | Limb-Girdle muscular dystrophy (LGMD) |
| | Recent data show that CMD and LGMD can overlap both clinically and genetically, which suggests that the underlying pathology may follow similar pathways. | | | In CMD, onset of symptoms is at birth or within the first 6 months of life; in LGMD onset of symptoms is in late childhood, adolescence or even adult life. | | | The Congenital Muscular Dystrophies (CMD) and the Limb-Girdle Muscular Dystrophies (LGMD) are common forms of highly heterogeneous muscular dystrophies which can be distinguished by their age at onset. |
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http://www.dmd.nl/LGMD.html
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| | Home |
| | Clinical and Neurophysiological improvement has continued to be seen since March 14th 2001 in patients who have Muscular Dystrophy | | | After 10 years of study and 4 years of successful results from | | | Cases of Muscular Dystrophy and Muscular Atrophy, accepted for treatment. |
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http://www.rocein.gr/royalcells
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| | BioMed Central Abstract Limb-Girdle Muscular Dystrophy |
| | Despite this clinical homogeneity, at least 15 different genetic forms of LGMD are now known. | | | Still others introduce totally unique pathogenetic mechanisms to the study of muscular dystrophy. | | | For example, LGMD 2H appears to be due to mutations affecting the ubiquitin-proteasome pathway. |
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http://www.biomedcentral.com/1528-4042/3/78/abstract
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| | Energy Citations Database (ECD) Document #465923 - Genetic and physical mapping at the limb-girdle muscular ... |
| | YACs selected from our contig will be the starting point for the cloning of the LGMD2B gene and thereby establish the biological basis for this form of muscular dystrophy and its relationship with the other limb-girdle muscular dystrophies. | | | The limb-girdle muscular dystrophies (LGMD) are a genetically heterogeneous group of disorders, different forms of which have been mapped to at least six distinct genetic loci. | | | Use of these most closely linked markers will help to determine the relationship between LGMD2B and Miyoshi myopathy. |
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http://www.osti.gov/energycitations/product.biblio.jsp?osti_id=465923
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| | Muscular Dystrophy / Atrophy |
| | Peroneal Muscular Atrophy (Charcot-Marie-Tooth Disease), Friedreich's Ataxia, Dejerine-Sottas Disease. | | | Spinal Muscular Atrophies: Motor Neurone Disease Infantile Progressive Spinal Muscular Atrophy (Werdnig-Hoffmann Disease), Juvenile Progressive Muscular Atrophy (Kugelberg- Welander Disease), Benign Congenital Hypotonia, Adult Progressive Spinal Muscular Atrophy (Aran-Duchenne Type) |
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http://www.kumc.edu/gec/support/muscular.html
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| | Limb girdle muscular dystrophy Information Diseases Database |
| | Limb girdle muscular dystrophy to medical search engines. | | | Search using Internet medical databases ; Search using Internet search engines (non-specialist) ; ; | | | If your browser has no JavaScript you can still use these: |
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http://www.diseasesdatabase.com/ddb32189.htm
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| | Breast Cancer Forum - Limb Girdle Muscular Dystrophy |
| | If this is your first view, please take a moment to register so you can start interacting with others. | | | Schizophrenia pregnancy calander health medical symptoms business research and intelligence health forums printer ink cartridges | | | Are there someone you know that has it and would like to respond back? |
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http://www.ehealthforum.com/health/topic977.html
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| | Muscular Dystrophy Association Diseases |
| | Juvenile Spinal Muscular Atrophy (SMA, SMA3 or KW) | | | Infantile Progressive Spinal Muscular Atrophy (SMA, SMA1 or WH) | | | (Also known as Hereditary Motor and Sensory Neuropathy (HMSN) or Peroneal Muscular Atrophy (PMA)) |
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http://www.mdausa.org/disease/index.html
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| | Las Vegas SUN: Members of LV High's Class of '44 hold reunion |
| | The disease killed his brother Butch, a Las Vegas firefighter who co-founded the national Muscular Dystrophy Association firefighter boot drive. | | | Snider, 77, born and raised in Las Vegas, was a longtime credit union manager who in the last decade has waged a courageous battle against limb-girdle muscular dystrophy. | | | Jerry and his wife, Pat, have four children and four grandchildren. |
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http://www.lasvegassun.com/sunbin/stories/lv-ed/2004/sep/20/517539305.html
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