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| | University of Miami School of Medicine - Glossary - Ketonuria |
 | | Ketone bodies are a byproduct of this process. |  | | Related words include "ketogenesis" (production of ketone bodies), "ketosis" or "ketonemia" (the presence of ketone bodies in the blood) and "ketotic" (adjective describing conditions involving ketone bodies). |  | | Ketone Bodies: What They Are, How They Accumulate |
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http://www.med.miami.edu/glossary/art.asp?articlekey=12478
(710 words)
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| | HEALTH AND FITNESS GLOSSARY AND DEFINITIONS: K |
 | | The accumulation of ketone bodies in the body, accompanied by a state of acidosis. |  | | The ability of individuals to feel where their bodies are in relation to space; a body awareness. |  | | Under these conditions acetoacetate is formed, which may convert then convert into one of two other ketone bodies, 3-hydroxybutarate, or acetone. |
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http://www.1-fitness.com/glossary.asp?page=K
(330 words)
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| | Use Of Ketone Bodies Diabetic-Network.com Use Of Ketone Bodies |
 | | Various tissues in the body, especially muscle, can use ketone bodies as a source of energy. |  | | Explain how the use of ketone bodies by the brain... |  | | This allows heart and skeletal muscle to use ketone bodies... |
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http://www.diabetic-network.com/diabetes/use-of-ketone-bodies.html
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| | Welcome to Parrillo Performance |
 | | Ketones can also be excreted by the body when not used, therefore not being converted to bodyfat. |  | | This process is termed "ketogenesis"ó which simply means the manufacture of ketones. |  | | Coupled with MCTs ability to spare glycogen, the conversion of MCTs into ketones represents an additional source of energy for the exercising body. |
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http://www.parrillo.com/sngdetails.asp?sng=tsb&id=3
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| | LowCarbSite :: View topic - ketosis article |
 | | In 1967, the streamline health sciences developed a so-called enzymatic method of analysis of acetoacetate and 3-hydroxybutyrate, which led to the dramatic finding that the human brain, while in the condition of prolonged starvation, was able to use ketone bodies. |  | | The body gets rid of it through the lungs; this is where the sweet smell on the breath during ketosis comes from. |  | | It's the body's way of saying "Whoa, we haven't used what we have yet!" and then figuring out what to do with the excess. |
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http://www.lowcarbsite.com/forum/ptopic3703.html
(4541 words)
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| | Ketogenic Diet Overview |
 | | Playing another major physiological role, ketone bodies act as the principle source of energy during early postnatal development. |  | | Clearly, many questions remain about the physiological relevance and the practical utility of monitoring ketone bodies in the ketogenic diet. |  | | The purpose of this review is to update neurologists by highlighting key issues and controversies pertaining to this important diet-based therapy for epilepsy. |
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http://www.charliefoundation.org/noframes/diet/overview.php
(2840 words)
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| | ketone bodies - General Practice Notebook |
 | | Ketonaemia, ketones in the bloodstream, is a physiological consequence of lipid metabolism. |  | | Ketones are a valuable energy source for tissues such as the brain and muscle. |  | | Ketogenesis is the normal pathway by which ketones are formed in the liver. |
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http://www.gpnotebook.co.uk/medwebpage.cfm?ID=-147521478
(814 words)
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| | [No title] |
 | | The quantitative monitoring of blood ketone bodies is the standard means of evaluating therapeutic progress in ketoacidosis in the clinical setting. |  | | Monitoring levels of ketone bodies is an essential aspect of sick-day management. |  | | Thus an accurate quantitative assessment of ketone bodies in the blood provides a much more valuable insight in determining current metabolic status and treatment strategy. |
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http://www.mdspharm.co.il/files/bioscanner-keton.doc
(3130 words)
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| | MedlinePlus Medical Encyclopedia: Serum ketones |
 | | A normal test result would be "negative", meaning there are no ketone bodies in the blood. |  | | Acetone bodies; Ketones - serum; Nitroprusside test; Ketone bodies - serum |  | | The only risks are those associated with the venipuncture. |
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http://www.nlm.nih.gov/medlineplus/ency/article/003498.htm
(695 words)
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| | Epi-Center E-Newsletter December 2004 - Happy Holidays! |
 | | The first step in the no-carb or extremely low-carb pathway to death is called ketosis. |  | | It also doesn't mean you can't do something good for your body. |  | | This range can be between 7.0 and 7.8 in extreme conditions. |
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http://www.firstfitnessoforlando.com/December_2004.htm
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| | Mechanism of ketosis, ketogenesis, gluconeogenesis, ketone bodies |
 | | The other ketone bodies are formed from it. |  | | This is then exported via the blood to the rest of the body, including the heart, muscles and brain, which seem to love this semi-digested form of fat! |  | | A large amount of energy is released during this process, which can be used for muscle contraction and all of the other activities in the cell and, ultimately, in the body. |
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http://academic.sun.ac.za/med_physbio/med_physiology/dept/footnote.htm
(396 words)
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| | Fatty Acid Metabolism |
 | | This pathway leads to the formation of ketone bodies. |  | | Fatty acid breakdown however must still occur for ATP generation and acetyl-CoA will need to be processed through an alternative pathway. |  | | The production of ketone bodies under these conditions is an important survival mechanism used by cells under such conditions. |
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http://www.np.edu.sg/~dept-bio/biochemistry/aab/topics/aab_lipid.htm
(881 words)
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| | APStracts 7:0630H, 2000. |
 | | Diabetic rat hearts perfused with glucose alone or with ketone bodies, had functional recoveries 50% lower than those of the control hearts, but palmitate restored recovery to control levels. |  | | In control rat hearts, neither palmitate nor ketone bodies altered the recovery of contractile function. |  | | In parallel with the functional recoveries, palmitate prevented the 54% faster loss of ATP in the diabetic, glucose-perfused rat hearts during ischemia, but had no effect on the rate of ATP depletion in control hearts. |
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http://www.uth.tmc.edu/apstracts/2000/heart/December/630h.html
(307 words)
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| | Copper-y smell? |
 | | The rest of her body does, too, but not as intensely as her hands. |  | | "Without trying to be too technical I think you can probably say that this ketone body smell is a consequence of fat metabolism. |  | | It is different from an ammonia- like smell that might result from muscle (protein) breakdown. |
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http://www.medhelp.org/forums/Diabetes/messages/74a.html
(663 words)
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| | Post-exercise ketosis, ketone bodies |
 | | (Remember that ketone bodies are produced as a consequence of the gluconeogenic process. |  | | If it were not for ketone bodies most of us would be unconscious after 48 hrs of fasting! |  | | The ketone bodies have a distinctive smell, which can be detected in the breath. |
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http://academic.sun.ac.za/med_physbio/med_physiology/dept/ketosis.htm
(1735 words)
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| | Fatty acid oxidation and ketone bodies |
 | | This allows the heart and skeletal muscles primarily to use ketone bodies for energy, thereby preserving the limited glucose for use by the brain. |  | | The human body produces carnitine through an enzymatically catalyzed |  | | Ketone bodies are utilized by extrahepatic tissues through the conversion of |
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http://www.med.unibs.it/~marchesi/fatox.html
(2711 words)
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| | Ketone bodies - Wikipedia, the free encyclopedia |
 | | Ketone bodies can also be used for energy. |  | | The three ketone bodies are acetoacetate, beta-hydroxybutyrate and acetone. |  | | The brain gets its energy from ketone bodies in starvation (when there's no glucose). |
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http://en.wikipedia.org/wiki/Ketone_bodies
(441 words)
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| | Report on Research on Rare Diseases in Children: FY 2000 to FY 2005 - National Institute on Alcohol Abuse and ... |
 | | Ketone bodies also reduce the free NADP +,which is the major source of the detoxification of free radicals. |  | | High-ketone diet therapy may therefore become a practical method for lifelong treatment of these patients. |  | | The clinical phenotype of FRDA patients is indistinguishable from the phenotype of patients with familial -tocopherol (vitamin E) deficiency, and is different from patients with iron overload. |
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http://rarediseases.info.nih.gov/html/reports/fy2000child_ht/niaaa.html
(2221 words)
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| | [No title] |
 | | Instead, the liver uses ketone bodies to get the energy of the acetyl CoA out to the peripheral tissues, where it can be processed and turned into energetically useful forms. |  | | concentration of acetone is very low, generally not a problem for the body. |  | | Ketone Bodies Characteristics of ketone bodies Three compounds known as ketone bodies: acetoacetic acid, (-hydroxy butyric acid, acetone Normally don’t hurt cells in any way heart tissue prefers ketone bodies to carbohydrate Ketone bodies are produced in the presence of high acetyl CoA concentration. |
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http://www.uhmc.sunysb.edu/som/students/2003/Lectures/cell31.doc
(2432 words)
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| | BioCarta - Charting Pathways of Life |
 | | Ketone bodies are transported to other tissues such as brain, muscle or heart where they are converted back to acetyl-CoA to serve as an energy source. |  | | In the metabolic condition called ketosis, ketone bodies are produced faster than they are consumed by tissues and the smell of acetone can be detected on a person's breath. |  | | The brain normally uses only glucose for energy, but during starvation ketone bodies can become the main energy source for the brain. |
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http://www.biocarta.com/pathfiles/ketonebodiesPathway.asp
(183 words)
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| | Ch438_Bioch Review |
 | | Under what conditions will "ketone bodies" be formed (instead of complete oxidation). |  | | answer: High [ATP] with continued breakdown of FA's, therefore need to form ketone bodies to recycle CoA. |  | | Know reactions by which ketone bodies are synthesized and degraded. |
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http://www.humboldt.edu/~rap1/C438.S04/C438Review/Wk14_review.html
(547 words)
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| | Glossary of genetic disorders. |
 | | A condition of having ketone bodies build up in body tissues and fluids. |  | | Ketones that build up in the body for a long time lead to serious illness and coma. |  | | The body can also rid itself of one type of ketone, called acetone, through the lungs. |
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http://aspin.asu.edu/geneinfo/glos-k.htm
(405 words)
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| | Fatty Acids -- Overview |
 | | It is considered to be physiologically equivalent to one because it and acetoacetate are readily interconverted in the body. |  | | These are the compounds known as ketone bodies. |  | | Notice that beta-hydroxybutyrate is not chemically a ketone. |
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http://www-medlib.med.utah.edu/NetBiochem/FattyAcids/10_1.html
(51 words)
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| | APStracts 2:0115C, 1995. |
 | | Lbthe references were done using reference manager utilization and preferred metabolic pathway of ketone bodies for lipid synthesis by isolated rat hepatoma cells. |  | | The results are discussed in terms of the known and proposed metabolic pathways for lipid synthesis from ketone bodies, particularly that from 3-hydroxybutyrate. |  | | Subcellular distribution studies indicated accumulation and compartmentation of 3-hydroxybutyryl CoA primarily in the cytoplasm of hepatoma cells incubated with either ketone body. |
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http://www.uth.tmc.edu/apstracts/1995/cell/March/115c.html
(212 words)
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| | Ketone Bodies in the Treatment of Disease - Office of Rare Diseases |
 | | A metabolic control analysis of th actions of ketones bodies in perfused heart |  | | Ketone Bodies in the Treatment of Disease - Office of Rare Diseases |  | | Panel on Preparation of Ketone Bodies and Precursors |
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http://rarediseases.info.nih.gov/html/workshops/workshops/ketone2003.html
(141 words)
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| | NATIONAL ACADEMY OF CLINICAL BIOCHEMISTRY |
 | | The test should not be used to monitor the course of therapy since levels of ACAC and AN may rise as levels of BHBA fall during successful therapy(2-8). Blood ketone determinations that measure BHBA specifically are useful for both diagnosis and ongoing monitoring of DKA(7,16-18). |  | | Blood ketone determinations that rely on the nitroprusside reaction should be used with caution for diagnosis of DKA as results do not quantify BHBA the predominant ketone in DKA). |  | | Recommendation: Ketones should be measured in urine by both patients with diabetes and in the clinic/hospital setting as an adjunct for the diagnosis of diabetic ketoacidosis. Only specific determinations of beta-hydroxybutyrate in blood should be used to establish a definitive diagnosis of diabetic ketoacidosis and to facilitate ongoing monitoring of ketoacidosis. |
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http://www.nacb.org/temporary/ketone.htm
(443 words)
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| | Arwen's Journal - The Book of Arwen » Ketone Bodies |
 | | During days 1-5, energy levels can flucuate from average to well below average (Feeling light headed, at times, is not uncommon). |  | | In the absence of food (Energy), Ketone bodies are produced by the body as an alternate energy source. |  | | Starvation, is the point where the body has used up all of its non-essential tissues (Reserves),and begins to break down its own essential tissues. |
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http://www.arwensloft.com/journal/index.php?p=132
(862 words)
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| | Lipid Catabolism |
 | | catalyzes inter-conversion of the ketone bodies acetoacetate and |  | | Acetyl-CoA then is converted in liver mitochondria to ketone bodies, |  | | Ketone bodies are transported in the blood to other tissue cells, where they are converted back to acetyl-CoA for catabolism in Krebs cycle (see p. |
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http://www.rpi.edu/dept/bcbp/molbiochem/MBWeb/mb2/part1/fatcatab.htm
(1147 words)
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| | Ketosis - Wikipedia, the free encyclopedia |
 | | Ketosis, which is one of the body's processes for the metabolism of body fat, should not be confused with ketoacidosis, a medical condition induced by diabetes, that is usually accompanied by dehydration, hyperglycemia, and insulin deficiency. |  | | During the initial stages of starvation the brain does not burn ketones, since they are an important substrate for lipid synthesis in the brain. |  | | Ketosis (key-toe-sis) is a stage in metabolism occurring when the liver has been depleted of stored glycogen and switches to a fasting mode such as occurs during sleep, during dieting, and during the body's response to starvation. |
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http://en.wikipedia.org/wiki/Ketosis
(495 words)
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| | Fatty Acids -- Ketone Bodies: Answer |
 | | Ketone bodies are used by most aerobic tissues, particularly heart and muscle. |  | | Ketone bodies are synthesized in the liver mitochondria, which is where HMG CoA lyase is expressed. |  | | Hence the liver is a net exporter of ketone bodies. |
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http://www-medlib.med.utah.edu/NetBiochem/FattyAcids/faq/1_11a.html
(104 words)
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| | Life Enhancement:: Ketone Bodies in Energy, Neuroprotection, . . . |
 | | They also suggest that ketones might be a beneficial treatment for elderly patients or others suffering from oxidative damage to mitochondria. |  | | found that d-beta-hydroxybutyrate, a ketone naturally found in rat and human metabolism, protected neurons in cell-culture models of Alzheimer’s and Parkinson’s diseases. |  | | Ketone bodies, natural metabolites produced from fatty acids, are sources of energy that can be used when there is insulin deficiency (which may be pathological, as in diabetes, or as a result of consuming low dietary carbohydrate) or mitochondrial senescence. |
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http://www.life-enhancement.com/article_template.asp?ID=885
(794 words)
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| | Ketone bodies Ask the Dietician vhi.ie |
 | | Ketone bodies are derived from fat and are the main source of energy used by the brain during starvation. |  | | Remember, vital organs such as the heart and kidneys are made of muscle tissue. |  | | This has the effect of sparing the body's muscle and organ tissue which otherwise would quickly become depleted and would dramatically reduce survival time during starvation. |
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http://www.vhihealthe.com/experts/diet/diet_q071.jsp
(252 words)
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| | Role of glucose and ketone bodies in the metabolic control of experimental brain cancer |
 | | Our results in a mouse astrocytoma suggest that malignant brain tumours are potentially manageable with dietary therapies that reduce glucose and elevate ketone bodies. |  | | This contrasts with normal brain tissue that can derive energy from both glucose and ketone bodies. |  | | Role of glucose and ketone bodies in the metabolic control of experimental brain cancer |
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http://www.nature.com/cgi-taf/dynapage.taf?file=/bjc/journal/v89/n7/abs/6601269a.html
(288 words)
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| | Ketone Bodies Terms and Definitions at www.MedicalGlossary.org |
 | | The ketone bodies can be used as fuels by muscle and brain tissue. |  | | Home > Chemicals and Drugs > Organic Chemicals > Ketones > Ketone Bodies Terms and Definitions |  | | acetonemia, acetonuria, ketonemia & ketonuria go here; ketogenesis is probably KETONE BODIES /biosyn |
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http://www.medicalglossary.org/ketones_ketone_bodies_definitions.html
(197 words)
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| | Alcoholic ketoacidosis at autopsy. Pounder DJ, Stevenson RJ, Taylor KK . 1998;43(4): 812-816. |
 | | Three of 12 diabetics had extreme elevations of femoral blood ketone bodies: 87.5, 20.4, and 17.4 mM/L. Measurement of ketone bodies in vitreous humour or pericardial fluid using clinical laboratory methodologies is recommended in unexplained deaths in chronic alcoholics as well as diabetics. |  | | This opens up the possibility of using simpler clinical laboratory methodologies which cannot be applied to autopsy blood due to hemolysis. |  | | Vitreous ketone levels showed good correlation with blood and pericardial fluid levels, suggesting that vitreous could be used as an alternative autopsy specimen for this analysis. |
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http://www.astm.org/jforensicsci/PAGES/2836.htm
(258 words)
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| | Word List |
 | | Kartagener's Syndrome *KS* - a condition where the heart is located on the right side of the body in patients with Immotile Cilia Syndrome |  | | transer of a kidney from the body of one person to another |  | | chemical test used to detect the presence of ketone bodies in the urine; if positive, fats are being utilized by the body instead of carbohydrates, which occurs in starvation or an unstable diabetic state |
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http://www.angelfire.com/wv/MT/klist.html
(482 words)
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| | abstract |
 | | Under conditions of fasting or caloric restriction (CR), however, brain cells can also derive energy from ketone bodies (acetoacetate and beta-hydroxybutyrate). |  | | Seizure susceptibility, body weights, and the levels of plasma glucose were measured once a week over a ten-week treatment period in each diet group. |  | | Glucose uptake into the brain is greater during epileptic seizures than during most other brain activities suggesting a key role for glucose in the initiation and spread of seizure activity. |
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http://www.hscbklyn.edu/http://Alumni/kingsbrook/seyfried.html
(423 words)
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| | Kelp, Ketone bodies, Ketosis, Kidneys |
 | | When severe, ketosis is known as ketoacidosis, because the body becomes over-acidified due to the acidity of two of the ketone bodies. |  | | In all these cases the body is forced to use fat as an alternative energy source, and free fatty acids in the circulation are converted to ketone bodies in the liver. |  | | Conditions leading to ketosis are fasting or starvation, a shortage of carbohydrate, or uncontrolled diabetes mellitus which results in the body's inability to utilize carbohydrate as an energy source. |
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http://www.health-diets.net/healthsearch/kelp.htm
(275 words)
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| | Ketone Bodies, Serum |
 | | -hydroxybutyrate (unmeasured) but treatment of ketoacidosis results in increased acetoacetate (measured) and thus a more positive "acetone&; reaction, before ketone bodies decrease. |  | | Determining the presence of ketone bodies is useful when isopropanol ingestion is suspected. |  | | Thus, as ketoacidosis is treated, an apparent positive Acetest® is found while there is an actual reduction of total plasma ketone body concentration. |
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http://www.labcorp.com/datasets/labcorp/html/chapter/mono/sc000100.htm
(376 words)
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| | Ketones - [Medical Test] |
 | | Some medications can cause the test to indicate that ketones are present when they are not. |  | | Dehydration may concentrate ketones in the urine, causing a falsely high result. |  | | Therefore, specific blood tests are generally done to more accurately measure ketones. |
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http://www.peacehealth.org/kbase/topic/medtest/hw7738/factors.htm
(100 words)
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| | Fatty Acid Metabolism |
 | | •For cells which rely primarily or solely (such as the brain) on carbohydrate metabolism, ketone bodies represent a major energy source during times of starvation.
|  | | •Ketone bodies are produced from condensation and degradation of acetyl-CoA molecules. |
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http://www.cameron.edu/~teds/5fats_files/slide0022.htm
(57 words)
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| | Ch438_Lec_36 |
 | | The limiting factor in using ketone bodies then becomes the ability of the liver to synthesis them, which requires the induction of the enzymes required for acetoacetate biosynthesis. |  | | In the peripheral tissues the ketones must be reconverted to acetyl CoA in the mitochondria: |  | | 's for both are similar, the CNS doesn't begin to use ketone bodies in preference to glucose until their concentration exceed's the concentration of glucose in the serum. |
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http://www.humboldt.edu/~rap1/C438.S04/C438Notes/C438nLec36.htm
(1113 words)
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