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Topic: Itraconazole



  
 m010409b - Itraconazole in Minimally-Invasive Apergilloma
Itraconazole therapy in aspergillosis: study in 49 patients.
Title: Itraconazole therapy in aspergillosis: study in 49 patients.
Itraconazole use should be restricted to patients who experience severe toxicity with amphotericin B therapy.
http://www.emory.edu/WHSCL/grady/amreport/litsrch00/s010409b.html   (2940 words)

  
 Onychomycosis: Improved Cure Rates with Itraconazole and Terbinafine
Mycologic cure rates at the end of follow-up were 94.1% for continuous terbinafine therapy, 80% for intermittent terbinafine therapy, and 75% for intermittent itraconazole therapy.
One study compared intermittent terbinafine therapy with intermittent itraconazole therapy and continuous terbinafine therapy,
Daily terbinafine therapy, however, appears to be more effective than pulse therapy with itraconazole.
http://www.familypractice.com/journal/2000/v13.n04/1304.06/art-1304.06.htm   (3174 words)

  
 Iatrogenic adrenal insufficiency as a side-effect of combined treatment of itraconazole and budesonide -- Skov et al. ...
Effects of itraconazole therapy in allergic bronchopulmonary aspergillosis.
Adrenal response to corticotropin during therapy with itraconazole.
Initial experience in therapy for progressive mycoses with itraconazole, the first clinically studied triazole.
http://erj.ersjournals.com/cgi/content/full/20/1/127   (2953 words)

  
 Sputum Itraconazole Concentrations in Cystic Fibrosis Patients -- Sermet-Gaudelus et al. 45 (6): 1937 -- Antimicrobial ...
Adjunctive therapy of allergic bronchopulmonary aspergillosis with itraconazole.
To our knowledge, this is the first study focusing on itraconazole diffusion in sputum of CF patients.
Eleven CF patients with ABPA, 5 to 15 years of age, were enrolled in the study during the usual monitoring of itraconazole
http://aac.asm.org/cgi/content/full/45/6/1937   (1031 words)

  
 The Effects of Formulation on the systemic Availability of Itraconazole in Pigeons
Itraconazole: a review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in superficial and systemic mycoses.
Dupont B, Drouhet E. Early experience with itraconazole in vitro and in patients: pharmacokinetic studies and clinical results.
Bioavailability and elimination of itraconazole are dose-dependent in humans.
http://www.lafeber.com/Lafeber-Library/itraconazole_pigeons.asp   (4672 words)

  
 Itraconazole-Induced Congestive Heart Failure
The patient, who had no other medical conditions and was on no other medicines at the time of the itraconazole therapy pulses, was admitted to hospital where he was assessed as being in heart failure.
If CHF develops during itraconazole use, the risk-benefit profile of continued treatment should be reassessed against the availability of other systemic antifungal medicines.
Five months into the second treatment period, the patient presented to his GP with significant weight gain (6kg in one month), peripheral oedema and dull left-sided chest pain.
http://www.medsafe.govt.nz/Profs/PUarticles/CHF.htm   (571 words)

  
 MedlinePlus Drug Information: Itraconazole
Talk to your doctor about the possible risks of using this drug for your condition.
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
Continue to take itraconazole even if you do not see any improvement.
http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a692049.html   (1266 words)

  
 A Mucoadhesive, Cyclodextrin-based Vaginal Cream Formulation of Itraconazole
The ability of HPβCD to solubilize itraconazole was assessed using phase-solubility techniques.
For irritation studies, a 2% itraconazole cream, a placebo cream, or a sham treatment were completed.
The development of vaginal medications, especially antifungal medications, requires that the drug is solubilized as well as retained at or near the mucosa for sufficient periods of time to ensure adequate bioavailability.
http://www.aapspharmsci.org/view.asp?art=ps050105   (2527 words)

  
 Efficacy of the Cyclodextrin Liquid Preparation of Itraconazole in Treatment of Denture Stomatitis: Comparison with ...
Itraconazole is clearly a very effective drug for use in the treatment of denture stomatitis.
Nine male and 31 female patients whose ages ranged from 29 to 81 years (mean, 62 years) entered the study.
cyclodextrin solution of itraconazole may provide a major therapeutic
http://aac.asm.org/cgi/content/full/44/2/425   (1440 words)

  
 Texas Medicaid Vendor Drug Program, Fluconazole (Diflucan®), Itraconazole (Sporanox®) and Terbinafine (Lamisil®) - ...
Concurrent therapy with itraconazole and dofetilide is not recommended and will be reviewed.
Concurrent therapy with itraconazole and pimozide is not recommended and will be reviewed.
The following drug-drug interactions are considered clinically relevant for fluconazole, itraconazole, and terbinafine.
http://www.hhsc.state.tx.us/HCF/vdp/Criteria/onychom.html   (1375 words)

  
 [No title]
Rhett Drugge, M.D. I treated the now 62 year old patient in 1994 with itraconazole pulse for T.pedis and onychomycosis which was quite severe.
Bill Liss --------- The patients that I have had problems with when treated with itraconazole had no underlying problems based on their medical history.
She presented again to her Internist in December-January of this year and was re prescribed itraconazole (third course) after normal LFTs.
http://matrix.ucdavis.edu/rxderm-archives/itraconazole   (380 words)

  
 News - Itraconazole Antifungal Shows Hepatic Safety
There were reports, in the literature, of symptomatic hepatitis with itraconazole continuous therapy but none of symptomatic hepatotoxicity with the pulse regimen.
To assess the hepatic safety of pulse and continuous itraconazole, the researchers analysed all itraconazole clinical trials sponsored by Janssen Research Foundation in the treatment of onychomycosis where there had been an assessment of laboratory safety.
The most common adverse events were gastrointestinal upset, headache, and transient skin reaction.
http://www.docguide.com/news/content.nsf/news/8525697700573E1885256BDF0054A110   (435 words)

  
 Optimization of Polylactic-Co-Glycolic Acid Nanoparticles Containing Itraconazole Using 2(3) Factorial Design
studied the association of itraconazole with colloidal drug carriers, except PLGA.
A relatively low value of the coefficient of variation (CV = 0.80) indicated improved precision and reliability of the conducted experiments.
A significant synergistic interaction between PLGA and itraconazole at
http://www.aapspharmscitech.org/view.asp?art=pt040471&pdf=yes   (2777 words)

  
 Drug Interaction Between Simvastatin and Itraconazole in Male and Female Rats -- Ishigami et al. 29 (7): 1068 -- Drug ...
Olkkola KT, Backman JT and Neuvonen PJ (1994) Midazolam should be avoided in patients receiving the systemic antimycotics ketoconazole or itraconazole.
whereas in male rats, itraconazole had no effect.
and itraconazole observed in humans could also occur in rats,
http://dmd.aspetjournals.org/cgi/content/full/29/7/1068   (3033 words)

  
 itraconazole Consumer Drug Information
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Your pharmacist has additional information about itraconazole written for health professionals that you may read.
Before taking itraconazole, tell your doctor if you are taking any other medicines, especially any of the following:
http://www.drugs.com/MTM/itraconazole.html   (1564 words)

  
 Itraconazole Prevents Invasive Fungal Infections in Neutropenic Patients Treated for Hematologic Malignancies: Evidence ...
Rex JH, Pfaller MA, Galgiani JN, et al: Development of interpretive breakpoints for antifungal susceptibility testing: conceptual framework and analysis of in vitro-in vivo correlation data for fluconazole, itraconazole, and candida infections: Subcommittee on Antifungal Susceptibility Testing of the National Committee for Clinical Laboratory Standards.
outcome for 3,597 patients (1,812 treated with itraconazole
Grant SM, Clissod SP: Itraconazole: A review of its pharmacodynamic and pharmacokinetik properties, and therapeutic use in superficial and systemic mycoses.
http://www.jco.org/cgi/content/full/21/24/4615   (4553 words)

  
 CATIE Fact Sheet : Itraconazole (Sporanox)
Although esophageal candidiasis is a serious condition, it can be effectively treated.
People with HIV use it most often to treat thrush.
Itraconazole is a drug taken to treat or prevent fungal infections.
http://www.catie.ca/facts.nsf/0/B3DEE0349A9AC9E8852566B9000574A2?opendocument&language=english   (430 words)

  
 ITRACONAZOLE
Inform your doctor and pharmacist of all prescribed and non-prescribed drugs you are taking.  As well, you should inform them of natural products you are taking.
You should NOT take the following drugs if your doctor has prescribed itraconazole:
What other PRECAUTIONS should you follow while using this drug?
http://www.tthhivclinic.com/FactSheets/html/ITRACONAZOLE.html   (537 words)

  
 Itraconazole - Patient UK
Before taking any 'over-the-counter' medicines, check with your pharmacist which medicines are safe for you to take alongside itraconazole.
Never give it to others even if their condition appears to be the same as yours.
Itraconazole is also sometimes used to prevent fungal infections occurring in patients with a lowered immune system.
http://www.patient.co.uk/showdoc/30002065   (738 words)

  
 Itraconazole. DermNet NZ
Congestive heart failure: itraconazole should be used with caution in those with heart problems.
These drugs should not be taken by those on itraconazole:
Itraconazole is an azole medicine used to treat fungal infections.
http://dermnetnz.org/treatments/itraconazole.html   (564 words)

  
 Serum itraconazole concentrations and clinical responses in Candida-associated denture stomatitis patients treated with ...
resulting from the itraconazole therapy was found to be very
There was no relationship between the serum and saliva itraconazole
The detection of itraconazole in the saliva of patients
http://jac.oxfordjournals.org/cgi/content/full/45/1/95   (2420 words)

  
 Itraconazole
Itraconazole is one of the most expensive medications in used in veterinary medicine.
These medications should not be used with itraconazole.
Itraconazole should not be given to patients with known liver disease if possible.
http://www.marvistavet.com/html/body_itraconazole.html   (637 words)

  
 Itraconazole
This drug works best when there is a constant amount of it in the bloodstream.
What special instructions should I follow while taking this medication?
Itraconazole is prescribed to transplant patients to treat or prevent the development of aspergillus infection, a type of fungal infection.
http://www.clevelandclinic.org/transplant/services/lung/guide/itraconazole.htm   (597 words)

  
 ITRACONAZOLE - INJECTABLE (Sporanox) side effects, medical uses, and drug interactions.
Itraconazole blocks the breakdown of these medications by the liver (via cytochrome P450 3A4) causing buildup of these drugs in your body.
ITRACONAZOLE - INJECTABLE (Sporanox) side effects, medical uses, and drug interactions.
Itraconazole may infrequently cause or worsen certain heart conditions (congestive heart failure).
http://www.medicinenet.com/itraconazole-injectable/article.htm   (443 words)

  
 Itraconazole
The intravenous formulation provides an intriguing new ability to deliver itraconazole effectively, but the full clinical relevance of this is not yet known.
Hypertension, hypokalemia, oedema, headache and alterations in mental status are seldomly observed [564].
Itraconazole solution: higher serum drug concentrations and better clinical response rates than the capsule formulation in acquired immunodeficiency syndrome patients with candidosis.
http://www.doctorfungus.org/thedrugs/Itraconazole.htm   (794 words)

  
 Nationwide Survey of In Vitro Activities of Itraconazole and Voriconazole against Clinical Aspergillus fumigatus ...
of itraconazole instead of the established twofold drug dilutions,
the patient to respond clinically to treatment with itraconazole.
Intravenous and oral itraconazole versus intravenous amphotericin B deoxycholate as empirical antifungal therapy for persistent fever in neutropenic patients with cancer who are receiving broad-spectrum antibacterial therapy.
http://jcm.asm.org/cgi/content/full/40/7/2648   (2305 words)

  
 Itraconazole - Drugs & Vitamins - Drug Library - DrugDigest
Check with your health care professional before stopping or starting any of your medicines.
Other drugs that may interact with itraconazole include:
Itraconazole - Drugs & Vitamins - Drug Library - DrugDigest
http://www.drugdigest.org/DD/DVH/Uses/0,3915,361Itraconazole,00.html   (642 words)

  
 TreatmentUpdate 87: Itraconazole solution for oral yeast infections
Although a number of drugs are available for this, fluconazole is probably the most popular choice in North America.
Decisions about particular medical treatments should always be made in consultation with a qualified medical practitioner who is knowledgeable about HIV-related illness and the treatments in question.
Itraconazole, an antifungal drug used to treat a number of life-threatening infections, has recently been produced in a liquid form, ensuring better absorption.
http://www.catie.ca/tu.nsf/0/E9102252B2EC6DF2852566890070636E?opendocument&languag   (485 words)

  
 itraconazole: Definition and Much More From Answers.com
Itraconazole is used with caution in any patient with liver dysfunction.
Itraconazole (Sporanox®) is an antifungal agent that is prescribed to patients with fungal infections.
The drug may be given orally or intravenously.
http://www.answers.com/topic/itraconazole   (575 words)

  
 Itraconazole Assay
Itraconazole is the drug of choice for oral treatment of histoplasmosis and blastomycosis and is often used for aspergillosis.
Itraconazole serum drug levels are important to monitor because absorption is variable and dosing may need to be adjusted to maintain the drug concentration in the therapeutic range of 1-10 ug/ml as measured by bioassay.
Itraconazole concentration is affected by drugs which lower gastric acidity and thereby reduce its absorption and by those which induce hepatic cytochrome P450 3A enzymes which accelerate itraconazole's metabolism.
http://www.iupui.edu/~histodgn/itrabio.html   (315 words)

  
 ADAP drugs: itraconazole
Itraconazole is a maintenance treatment for fungal infections and is being studied for prevention of histoplasmosis, and for treatment of mild cases of histoplasmosis and blastomycosis.
Itraconazole is available in pill form for systemic treatment of vaginal candidiasis.
You shouldn't take antacids, anticonvulsants or rifampin at the same time as itraconazole, because they can reduce the effectiveness of treatment.
http://www.atdn.org/access/drugs/itra.html   (423 words)

  
 Patient instructions for itraconazole
Itraconazole's therapeutic effect may be reduced by certain other medications, which should be avoided:
Itraconazole also interacts with a number of other medications to raise their blood level which can cause toxic side effects, which may be life threatening.
*For patients who must use these medications, the itraconazole solution may yield better serum drug levels because these medications reduce the absorption of the capsule formulation from the stomach.
http://www.iupui.edu/~histodgn/itra-ins.html   (196 words)

  
 Treatment of oral candidosis with itraconazole: a review.
Oral candidosis is a common infection in infants, elderly persons, patients receiving immunosuppressive therapy, and patients with acquired immunodeficiency syndrome (AIDS).
A study in AIDS patients with oropharyngeal candidosis demonstrated that itraconazole, 200 mg/day, and ketoconazole, 400 mg day, for 4 weeks give equivalent clinical cure rates and similar relapse rates.
A pilot study with an oral solution of itraconazole has given an impressive 100% clinical and mycological response rate within 1 week of treatment.
http://www.aegis.com/aidsline/1991/jan/M9110127.html   (415 words)

  
 Sporanox Online, Description, Chemistry, Ingredients - Itraconazole Capsules - RxList Monographs
Serious cardiovascular adverse events, including death, ventricular tachycardia, and torsades de pointes have occurred in patients taking itraconazole concomitantly with terfenadine.
Serious cardiovascular adverse events including death, ventricular tachycardia, and torsades de pointes have occurred in patients taking itraconazole concomitantly with cisapride.
Based on results of an in vitro study and the chemical resemblance of itraconazole and ketoconazole, coadministration of astemizole and itraconazole is contraindicated.
http://www.rxlist.com/cgi/generic/itraconazole.htm   (272 words)

  
 ITRACONOZOLE a Commonly Used Medication
Itraconazole should not be given with terfenadine, cisapride, or astemizole may result in cardiac dysrhythmias and death.
Midazolam, triazolam, or digoxin levels may increase on itra.
Absorption requires gastric acidity, and H2 antagonists such as cimetidine should not be co-administered with itraconazole.
http://www.hivdent.org/drugs/ITRACONOZOLE.htm   (123 words)

  
 Itraconazole versus fluconazole for prevention of fungal infections in patients receiving allogeneic stem cell ...
developed IFI on treatment (fluconazole 15% versus itraconazole
From the Program of Infectious Diseases, Fred Hutchinson Cancer Research Center, Seattle, WA; the Program of Clinical Statistics, Fred Hutchinson Cancer Research Center, Seattle, WA; the Department of Medicine, University of Washington, Seattle; and the Department of Laboratory Medicine, University of Washington, Seattle.
Itraconazole versus fluconazole for prevention of fungal infections in patients receiving allogeneic stem cell transplants
http://www.bloodjournal.org/cgi/content/abstract/103/4/1527   (485 words)

  
 U.S. Labeling Changes Announced For SPORANOX® (itraconazole)
Physicians should carefully review the risks and benefits of therapy across all SPORANOX® indications for patients with risk factors for congestive heart failure.
Children With ADHD Experience Greater Reduction Of Behavioral Symptoms With Higher Doses Of CONCERTA® (methylphenidate HCl) vs. Methylphenidate, Study Shows
Co-administration of dofetilide and itraconazole may increase blood concentrations of dofetilide, possibly leading to serious adverse effects.
http://www.jnj.com/news/jnj_news/20020308_0807.htm   (661 words)

  
 Antifungal activity of itraconazole compared with hydroxy-itraconazole in vitro -- Odds and Bossche 45 (3): 371 -- ...
itraconazole alone by a more sensitive procedure such as HPLC.
The results of this study indicate that, among the 1481 fungal
Differential antifungal activity of itraconazole and hydroxy-itraconazole in vitro expressed as number of dilutions difference of itraconazole IC minus hydroxy-itraconazole IC Among the 206 isolates of C.
http://jac.oxfordjournals.org/cgi/content/full/45/3/371   (1302 words)

  
 itraconazole - OneLook Dictionary Search
itraconazole : The On-line Medical Dictionary [home, info]
ITRACONAZOLE (SPORANOX) : CPCRA AIDS Specific and Clinical Trials Terminology [home, info]
itraconazole : Dictionary of Cancer Terms [home, info]
http://www.onelook.com/?w=itraconazole&ls=a   (134 words)

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