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| | Data Sheet |
 | | Isoflurane potentiates the muscle relaxant effect of all muscle relaxants, most notably non-depolarizing muscle relaxants, and MAC (minimum alveolar concentration) is reduced by concomitant administration of N | | | General: As with any potent general anaesthetic, Isoflurane should only be administered in an adequately equipped anaesthetizing environment by those who are familiar with the pharmacology of the medicine and qualified by training and experience to manage the anaesthetized patient. | | | Isoflurane markedly increases cerebral blood flow at deeper levels of anaesthesia. |
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http://www.medsafe.govt.nz/profs/Datasheet/f/Foraneliqgas.htm
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| | The Rate Of Decline Of Exhaled Concentrations Of Isoflurane With And Without Nitrous Oxide |
| | For technique 2, the PAS monitor indicated 1% exhaled concentration of isoflurane, with nitrous oxide at 70% (2 liter flow) and oxygen at 30% (1 liter flow). | | | For technique 1, the photoacoustic spectrometer (PAS) monitor indicated an exhaled concentration of 1.0% isoflurane, with nitrous oxide at 70% (2 liter flow) and oxygen at 30% (1 liter flow). | | | At the same time, the liter of flow for oxygen was changed from 1 liter to 3 liters to compensate for the loss of liters of nitrous oxide flow. |
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http://www.ispub.com/journals/IJA/Vol3N4/secondgas.htm
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| | Isoflurane - Drugs & Vitamins - Drug Library - DrugDigest |
| | Isoflurane is given through inhalation (breathing the gas into the lungs) by trained anesthesia professionals in a controlled environment like an operating room before and during surgery or procedures. | | | General anesthesia is commonly used for extensive and long surgeries, but also can be used in shorter and limited procedures. | | | During your surgery or procedure the anesthesiologist will closely monitory all your body systems and treat any serious side effects. |
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http://www.drugdigest.org/DD/PrintablePages/Monograph/0,7765,8034Forane,00.html
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| | Isoflurane Preconditioning Induces Neuroprotection against Ischemia via Activation of P38 Mitogen-Activated Protein ... |
| | Values in graphs are expressed as -fold change over the isoflurane exposure (Iso-pre) only and presented as the means ± S.D. < 0.05 compared with isoflurane exposure only rats. | | | Kawaguchi M, Kimbro JR, Drummond JC, Cole DJ, Kelly PJ, and Patel PM (2000) Isoflurane delays but does not prevent cerebral infarction in rats subjected to focal ischemia. | | | Yang J and Zorumski CF (1991) Effects of isoflurane on N-methyl- |
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http://molpharm.aspetjournals.org/cgi/content/full/65/5/1172
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| | (S-37) INTERACTION OF PROTAMINE WITH ISOFLURANE IN RAT MYOCARDIUM |
| | The goal of this experimental study was to assess the inotropic and lusitropic responses to the association of protamine and isoflurane in rat myocardium. | | | M on the inotropic response to both protamine and isoflurane was also investigated. | | | of 1.0 mmol/l, protamine induced a negative inotropic effect, which was not significantly changed by isoflurane. |
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http://www.iars.org/abstracts/abstracts/S25/s37.htm
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| | Isoflurane |
| | Thirty minutes prior to the completion of the procedure isoflurane was discontinued, but oxygen continued to flow. | | | Minimal Alveolar Concentration (MAC; %) in oxygen reported for isoflurane in various species: Dog = 1.5; Cat = 1.2; Horse = 1.31; Human = 1.2. | | | Lateral recumbency and anaesthesia were achieved with etorphine (anaesthesia 1 and 2) or etorphine and azaperone (anaesthesia 3). |
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http://www.elephantcare.org/Drugs/isoflura.htm
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| | ENFLURANE HALOTHANE ISOFLURANE - (Organic Method #103) |
| | These are the amounts of each analyte that will give a response that is significantly different from the background response of a reagent blank. | | | Enflurane and isoflurane have similar health effects for acute exposure. | | | The recoveries of enflurane, halothane and isoflurane from samples used in the |
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http://www.osha.gov/dts/sltc/methods/organic/org103/org103.html
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| | University of Iowa Anesthesia Publications |
| | In rats treated with phenobarbital, however, isoflurane increased plasma fluoride over two times that in rats exposed to TFE alone. | | | Acute stimulation of trifluoroethene defluorination and cytochrome P450 inactivation in the rat by exposure to isoflurane. | | | The effect of isoflurane on trifluoroethene (TFE) defluorination and cytochrome P450 inactivation was examined in rats to determine the influence of this anesthetic on in vivo fluoroethene metabolism. |
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http://www.anesth.uiowa.edu/readabstract.asp?PMID=1585371
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| | (S-255) HIGH DOSE ISOFLURANE INCREASES BRAIN TISSUE OXYGENATION IN DOGS |
| | METHODS: Six dogs were anesthetized, intubated and venti- lated with isoflurane for surgery. | | | The purpose of this study was to determine whether high dose isoflurane anesthesia can produce a similar effect in dogs and the importance of cerebral perfusion pressure in mediating this effect. | | | Normal brain vascular regulation that limits hyperperfusion and hyperoxygenation of brain tissue is antagonized by high dose isoflurane and this can enhance brain capillary and tissue oxygenation if blood pressure is supported. |
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http://www.iars.org/abstracts/abstracts/S242/s255.htm
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| | Constructing an isoflurane box to anesthetize venomous snakes |
| | Remember not to anesthetize yourself while inducing the patient. | | | Isoflurane is an irritant, so be careful not to drip any into the chamber or on the animal's skin. | | | This is a standard 7 cup, 4.0 liter Rubbermaid container. |
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http://www.kingsnake.com/snakegetters/demo/vet/isobox.html
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| | isoflurane in asthma |
| | Johnston RG Isoflurane therapy for status asthmaticus in children and adults. | | | are known to relieve bronchospasm; diethylether and cyclopropane were used before the introduction of modern halogenated agents like halothane, isoflurane or enflurane. | | | Handel J. Inhaled anesthetics for refractory childhood asthma. |
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http://pedsccm.wustl.edu/All-Net/english/pulmpage/asthma/asthma-10.htm
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| | Two Deaths Involving Isoflurane Abuse |
| | One case was a suicide and the other a multiple drug death including isoflurane. | | | abuse drugs, death, drugs of abuse, forensic science, isoflurane, toxicology | | | A review of the literature did not reveal blood and tissue concentrations of isoflurane. |
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http://www.astm.org/JOURNALS/FORENSIC/PAGES/2259.htm
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| | PharmGKB: isoflurane |
| | Submitted by: Dan Roden, MD involving ADRB1, ADRB2, KCNE1, KCNE2, KCNH2, KCNQ1, SCN5A, almokalant, amiodarone, amitryptiline, bretylium, bupivicane, cisapride, disopyramide, dofetilide, encainide, fluconazole, haloperidol, hydroquinidine, isoflurane, itraconazole, ketoconazole, lithium, loratadine, metoclopramide, nortriptyline, procainamide, quinidine, sematilide, sotalol, sulfamethoxazole, thioridazine hydrochloride, trimethoprim,, Long QT Syndrome, Proarrhythmia and Torsades de Pointes. | | | This work is supported by the NIH/NIGMS Pharmacogenetics Research Network and Database (U01GM61374). |
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http://www.pharmgkb.org/views/index.jsp?objId=PA450106&objCls=Drug
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| | Isoflurane: Carcinogenic Potency Database |
| | ISOFLURANE 26675-46-7 3160 M f sww inh 78w81 1879 0 1.52gm 6.09gm Baden;anes,69,750-753;1988 lun ala 30.0gm * P |
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http://potency.berkeley.edu/chempages/ISOFLURANE.html
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