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Topic: Islets of Langerhans



  
 pancreatic islets (islets of langerhans)
Developmental expression of proprotein-processing endoprotease furin in rat pancreatic islets.
Insulin release in aging: dynamic response of isolated islets of Langerhans of the rat to D-glucose and D-glyceraldehyde.
Metabolic adaption of pancreatic islet tissue in aging rats.
http://www.arclab.org/node_pages/257.html   (925 words)

  
 Diabetes: Human islets of Langerhans express Fas ligand a... @ HighBeam Research
The finding that human islet [Beta]-cells can express FasL is extremely significant in light, of evidence from rodents and front humans that Fas can be upregulated in islets under conditions when immune-cell infiltration of the pancreas is increased (7,18,19).
Considering that we report here, that, human islets express FasL constitutively, it follows that they may be especially prone to undergo apoptosis under conditions favoring upregulation of Fas, such as during the heightened immune responsiveness that follows islet transplantation.
in human islets, the apoptotic response to IL-1[Beta] is mediated by at least two pathways, only one of which is Fas-dependent.
http://www.highbeam.com/library/doc0.asp?DOCID=1G1:20755166&refid=ip_encyclopedia_hf   (4275 words)

  
 Diabetes: Islets of Langerhans generate wavelike electric... @ HighBeam Research
Islets of Langerhans were isolated from pancreases of mice (ICR strain), hamsters (Mesociretus auratus), rats (Wistar and Sprague-Dawley), and gerbus (Psamnomys obesus).
Therefore, we conclude that the islets have an FPM and functional signal propagation pathways.
The notion that islets may have a pacemaker has been proposed in the past on the basis of indirect evidence (20).
http://www.highbeam.com/library/doc0.asp?docid=1G1:18308124&refid=ink_tptd_g1   (3943 words)

  
 "Genetic Engineering & Xenotransplantation" by Shane T. Grey, Ph.D.
Another possibility is to use fetal tissue to grow new islets, but currently this is not technically possible, aside from the ethical considerations concerning the use of human embryos.
This is in contrast to the fact that we can survive quite well with as little as a third of our own islets.
The use of pig islets for instance, would not deter the immune system.
http://www.actionbioscience.org/biotech/grey.html   (2140 words)

  
 Excitation Wave Propagation as a Possible Mechanism for Signal Transmission in Pancreatic Islets of Langerhans -- ...
of the islets of Langerhans during in vitro experiments.
Images are acquired from Fura-2 experiments at 380-nm wavelength excitation with a time lag of 1 s, which corresponds to the time internal between frames.
inner regions of the islet, observed in some experiments.
http://www.biophysj.org/cgi/content/full/80/3/1195   (6766 words)

  
 [No title]
Langerhans also studied the anatomy of the skin and its innervation.
He was among the first investigators to successfully explore this new area of research using staining techniques and other innovative methods.
Langerhans is notable for his studies of human and animal histology.
http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=islet+of+langerhans   (129 words)

  
 Inhibition of Insulin Secretion by Leptin in Normal Rodent Islets of Langerhans -- Poitout et al. 139 (3): 822 -- ...
RT-PCR analysis of OB-Ra, OB-Rb, and OBR-f expression in isolated Wistar rat islets.
Batches of 10 islets isolated from normal Wistar rats were incubated
the expression of three isoforms of OB-R in isolated rat islets.
http://endo.endojournals.org/cgi/lookup?vol=139&fp=822&view=full   (4009 words)

  
 The Pancreas Center - Research
Isolation of pancreatic islets has been performed routinely in the laboratory for nearly three decades through a process that utilizes the protease activity of Collagenase.
Eric Liu, MD a P&S graduate, is presently a first year Post Graduate in the Department of Surgery.
Islet isolation may soon become a common therapy for Type I Diabetes.
http://www.columbiasurgery.org/programs/pancreas/research.html   (611 words)

  
 TGF-beta Plays a Key Role in Morphogenesis of the Pancreatic Islets of Langerhans by Controlling the Activity of the ...
Plays a Key Role in Morphogenesis of the Pancreatic Islets of Langerhans by Controlling the Activity of the Matrix Metalloproteinase MMP-2
This mechanism suggests that the extracellular matrix has to be
Tissue Inhibitor of Metalloproteinase-1 Prevents Cytokine-Mediated Dysfunction and Cytotoxicity in Pancreatic Islets and {beta}-cells
http://www.jcb.org/cgi/content/abstract/143/3/827   (961 words)

  
 Anyone know how Dr. Ulrichs' xeno research is progressing?
Workgroup Ulrichs/Thiede D3 Therapy of IDDM with microencapsulated porcine islets of Langerhans Improvement of the xenograft and its long-term function
Our long-term goal is to provide a functional, healthful islet graft from the pig for the therapy of patients who suffer from insulin-dependent diabetes mellitus ( Xenogeneic Islet Transplantation ).
In the process of optimizing the graft function, we plan to improve the isolation process, the microencapsulation (material and technology), the in vitro culture and function of porcine islets of Langerhans, as well as the analysis of the specific and unspecific immune reactions of the recipient to the graft.
http://www.islet.org/forum/messages/37282.htm   (304 words)

  
 Citysearch Attorneys
 Just do a search in Google (http://www.google.com) for “NEOPLASMS OF ISLETS OF LANGERHANS pharmacy” (or drugs or medicine) and you’ll find one that has what you are looking for. 
Need drugs, a pharmacy, or medicine for NEOPLASMS OF ISLETS OF LANGERHANS?
Or, perhaps you are looking for a NEOPLASMS OF ISLETS OF LANGERHANS treatment or an alternative cure?
http://www.stilltheking.com/resources2003.htm   (217 words)

  
 Insulin release in aging: dynamic response of isolated islets of Langerhans of the rat to D-glucose and ...
Insulin release in aging: dynamic response of isolated islets of Langerhans of the rat to D-glucose and D-glyceraldehyde.
Response to the secretagogues was delayed by 1 min in studies on islets from older rats.
The differences in the insulin secretory responses to D-glucose and D-glyceraldehyde in islets from older rats support the hypothesis that the major rate-limiting step in stimulus-secretion coupling in aging is before the metabolism of the trioses.
http://www.arclab.org/medlineupdates/abstract_3881248.html   (295 words)

  
 HONmeeting - Health Conferences & Event- Islets of Langerhans Transplantation
Analytical, Diagnostic and Therapeutic Techniques and Equipment / Surgical Procedures, Operative / Islets of Langerhans Transplantation
The keywords used on this page are the Medical Subject Headings developed by the National Library of Medicine®, USA © MeSH 2001
HONmeeting - Health Conferences & Event- Islets of Langerhans Transplantation
http://www.hon.ch/Conf/Theme/E04.270.550.html   (117 words)

  
 Technical Program Paper Detail - AIChE
(1) islets in culture on a planar surface, and (2) islets in a hydrogel matrix slab.
Transplantation of insulin-secreting islets of Langerhans is currently of high interest for curing
We have developed a theoretical model to examine this problem in several important situations:
http://www.aiche.org/conferences/techprogram/paperdetail.asp?PaperID=3263&DSN=annual01   (360 words)

  
 Quadrupole Magnetic Separation (Qms) of Porcine Islets of Langerhans
Alternatively, human clinical trials since the 1990's have investigated the feasibility of transplanting purified pancreatic islets instead of the whole organs.
Preliminary results indicate that Dynabeads® are not detrimental to islet function or vitality.
• Magnetic purification would subject islet cells to less mechanical and chemical stress.
http://aiche.confex.com/aiche/2005/techprogram/P17656.HTM   (430 words)

  
 Molecular Biology of the Islets of Langerhans - Cambridge University Press
The material presented here will be essential reading for researchers in human endocrinology and, in particular, for those working in the area of diabetes research.
The islets of Langerhans, the primary source of hormone production in the pancreas, have been the focus of research into the nature of diabetes for decades.
Molecular biology of the islets of Langerhans provides the first comprehensive treatment of molecular studies on the synthesis of insulin, glucagon, somatostatin and pancreatic polypeptide.
http://www.cambridge.org/uk/catalogue/catalogue.asp?isbn=0521362040   (439 words)

  
 Langerhans' islands (www.whonamedit.com)
Langerhans did not suggest any function for them.
Destruction or impairment of function of the islets of Langerhans may result in diabetes or hypoglycaemia.
The normal human pancreas contains about 1.000.000 islets.
http://www.whonamedit.com/synd.cfm/2225.html   (200 words)

  
 Islets of Langerhans - Uncyclopedia
The French have long since finished pouting(at least about the Isles of Langerhans), and fortunately for the tribes, no one else has expressed any desire to infringe on their autonomy.
The Endocrine tribe does hold the advantage of having the ability of processing foods, and thereby many cooks, for both tribes, are from the Endocrine.
There were many heated debates as to who should own the islands, because though Germany discovered the islands, they weren't allowed to have it because they were naughty.
http://uncyclopedia.org/wiki/Islets_of_Langerhans   (582 words)

  
 Diabetes Self-Management - Islets of Langerhans
But transplanting a whole pancreas involves a major, complex surgical procedure and requires the use of immunosuppressive drugs.
For this reason, researchers have been exploring the possibility of transplanting just the islets.
Over 300 experimental islet transplants have been performed worldwide since 1990, but so far, the success rate has been very low.
http://www.diabetes-self-mgmt.com/article.cfm?aid=402&sid=6   (357 words)

  
 IMM Projects - TEMPLATE
We have discovered a number of important new features appearing due to coupling, the most prominent is coherent wave propagation across the islets of Langerhans, revealed in experiments and image analysis studies at Novo Nordisk, Bioimage and IMM.
So far the investigations has been conducted on in vitro experiments of islets of Langerhans.
Abstract: Modelling and simulations are conducted on excitable beta-cells in the islets of Langerhans in the pancreas using the reaction diffusion type Hudgin-Huxley equations adapted to the description of beta-cells.
http://www.imm.dtu.dk/~mps/BetaCells-mps.html   (249 words)

  
 Islets from On-line Medical Dictionary
The transference of pancreatic islets within an individual, between individuals of the same species, or between individuals of different species.
Published at the Centre for Cancer Education, University of Newcastle upon Tyne
Next: islet tissue, -ism, -ismus, iso-, isoacceptor tRNA, isoagglutination
http://cancerweb.ncl.ac.uk/cgi-bin/omd?Islets   (76 words)

  
 AllRefer.com - islets of Langerhans (Anatomy And Physiology) - Encyclopedia
You are here : AllRefer.com > Reference > Encyclopedia > Anatomy And Physiology > islets of Langerhans
AllRefer.com - islets of Langerhans (Anatomy And Physiology) - Encyclopedia
More articles from AllRefer Reference on islets of Langerhans
http://reference.allrefer.com/encyclopedia/X/X-isletsLa.html   (115 words)

  
 About the Islets of Langerhans
I'm indebted, first and foremost, to Harlan Ellison himself for his enormous patience answering questions, offering suggestions and giving me an opportunity to get to know the generous spirit behind the cyclone.
I undertook this survey of Harlan Ellison's literary output in 1995, having forgotten just how bloody many books bear the guy's name.
A major revamp of the site in late 2002 included the site's first FAQ and the Islets sale table, featuring used Ellison first editions and reading copies.
http://www.islets.net/about.html   (270 words)

  
 Islets of Langerhans - Wikipedia, the free encyclopedia
The paracrine feed-back system of the Islets of Langerhans has the following structure:
Electrical activity of pancreatic islet-cells has been studied using the patch-clamp technique, and it has turned out that the behaviour of cells in intact islets differs significantly from the behaviour of dispersed cells
Islet cells can influence each other through paracrine and autocrine communication, and beta-cells are coupled electrically to beta-cells (but not to other cell-types!).
http://en.wikipedia.org/wiki/Islets_of_Langerhans   (230 words)

  
 GI Tract
The pancreas is most readily identified by the numerous Islets of Langerhans.
http://www.kumc.edu/instruction/medicine/anatomy/histoweb/gitract/gi40.htm   (22 words)

  
 Langerhans, islets of --  Encyclopædia Britannica
Center dedicated to the cure and treatment of the disease.
Includes details on research activities, and clinical islet trials and testing.
Brief information on the causes, symptoms, diagnosis, and treatment of this condition characterized an abnormal growth of cells in the islet cell region.
http://www.britannica.com/eb/article-9047095?tocId=9047095   (793 words)

  
 islets of Langerhans on Encyclopedia.com
Differential effects of hyperlipidemia on insulin secretion in islets of langerhans from hyperglycemic versus normoglycemic rats.
Glucose-induced regulation of COX-2 expression in human islets of Langerhans.(Lipid Modulators Of Islet Function)
http://www.encyclopedia.com/html/X/X-isletsL1a.asp   (544 words)

  
 children with DIABETES - Diabetes Dictionary: I
Although transplanting islet cells may one day help people with diabetes, the procedure is still in the research stage.
Although not usually cancerous, such tumors may cause the body to make extra insulin and may lead to a blood glucose (sugar) level that is too low.
Anti 21-hydroxylase (a test for Addison's disease, also an autoimmune condition found in 2% of new onset Type 1 diabetes)
http://www.childrenwithdiabetes.com/dictionary/i.htm   (1763 words)

  
 islets of Langerhans cell
Letter N Such cells may comprise a peripheral endocrine gland (eg, the insulin-secreting beta cells of the islets of Langerhans in the pancreas and the adrenaline...
tissue replacement of the acini with preserva- tion of the Islets of Langerhans.
The normal human pancreas contains about 1,000,000 islets.
http://www.cancer-help.org/cancer/0604/islets_of_Langerhans_cell.html   (350 words)

  
 Renal
ENDO040.jpg [312k] Islet of Langerhans demonstrating insulitis with lymphocytic infiltrates in a patient developing type I diabetes mellitus, microscopic.
Fibrosis and deposition of amylin polypeptide within islets are most characteristic of the chronic states of type II diabetes.
ENDO033.jpg [192k] Islet of Langerhans demonstrating amorphous pink deposition of amyloid in a patient with type II diabetes mellitus, microscopic.
http://www.md.huji.ac.il/mirror/webpath/DIABETES.html   (523 words)

  
 Example: Pancreas
The islets have a historical significance almost as great as their physiological one.
They represent one of many discoveries made during the tragically short life of Paul W. Langerhans (1847-1888), a German anatomist who was one of the seminal figures in the development of histology as a discipline.
It consists of cords or strings of cells, which in sections like this one take on the appearances of "islands" of tissue with marked staining differences from the surrounding acinar areas.
http://education.vetmed.vt.edu/Curriculum/VM8054/Labs/Lab24/EXAMPLES/EXENDPNC.HTM   (186 words)

  
 Cancer Spectrum: CANCERLIT® Citation
From these data, we conclude (i) that alternative splicing and/or the use of distinct tissue-specific promoters generate structurally distinct mRNA species in liver and islets of Langerhans and (ii) that tissue-specific transcription mechanisms result in inducible expression of the glucokinase gene in liver but not in islets during the fasting-refeeding transition.
In contrast, islet glucokinase mRNA is expressed at a constant level during the fasting-refeeding cycle.
The islets of Langerhans of the pancreas also contain glucokinase.
http://jncicancerspectrum.oxfordjournals.org/cgi/cancerlit/2682629   (286 words)

  
 Defining the cell lineages of the islets of Langerhans using transgenic mice
Biol., we summarize our own studies on the development of the mouse endocrine pancreas, with special emphasis on the cell lineage relationships between the four islet cell types.
The b-cell lineage analysis was started by selectively ablating specific islet cell types in transgenic mice.
Considerable knowledge concerning the ontogeny of the endocrine pancreas has been gained in recent years, mainly through the use of two complementary genetic approaches in mice: gene inactivation and genetic labelling of precursor cells.
http://www.ijdb.ehu.es/abstract.0201/a97.html   (296 words)

  
 Altered TNF-{alpha}, glucose, insulin, and amino acids in islets of Langerhans cultured in a microgravity model system ...
The present studies were designed to determine effects of a microgravity model system upon lipopolysaccharide (LPS)-stimulated
(1,726 ± 117, 150 islet equivalent units) from Wistar-Furth rats
and increased disappearance of arginine in islets cultured in
http://ajpendo.physiology.org/cgi/content/abstract/280/1/E92   (283 words)

  
 A Science Odyssey: People and Discoveries: Banting and Best isolate insulin
Macleod, back from holiday, was still skeptical of the results and asked them to repeat the experiment several more times.
In May, 1921, as Macleod took off for a holiday in his native Scotland, Banting and his assistant Charles Best began their experiments.
The connection was further narrowed down to the islets of Langerhans, a part of the pancreas.
http://www.pbs.org/wgbh/aso/databank/entries/dm22in.html   (584 words)

  
 Harlan Ellison / Islets of Langerhans
If you've found the information here useful and would like to support this project, please consider making a donation.
Islets of Langerhans is a noncommercial Web site, not associated (except by fond good wishes) with Harlan Ellison.
Published in paper and cloth by The Ohio State University Press (ironically, the college that Ellison got kicked out of).
http://www.islets.net   (252 words)

  
 Lexicon 2K - L's
Diabetes is a disorder where the Islets of Langerhans do not properly supply the body with insulin.
In 1869, Paul Langerhans, a German pathologist, described cells in the human pancreas which secrete insulin.
Well, the Islets of Langerhans aren't on any map.
http://www.benway.com/firesign/lexicon/L.html   (138 words)

  
 Oscillation of gap junction electrical coupling in the mouse pancreatic islets of Langerhans -- Andreu et al. 498 (3): ...
This allows the islet to be used as
Pancreatic beta-cells oscillate synchronously when grouped in islets.
Excitation Wave Propagation as a Possible Mechanism for Signal Transmission in Pancreatic Islets of Langerhans
http://jp.physoc.org/cgi/content/abstract/498/3/753   (435 words)

  
 NDI Terminology - pancreas
Most of the pancreas consists of exocrine tissue, embedded in which are "nests" of endocrine cells (the islets of Langerhans).
The islets of Langerhans are surrounded by many blood vessels into which they secrete hormones.
This duct joins the common bile duct (which carries bile from the gallbladder) to form a small chamber, called the ampulla of Vater, that opens into the duodenum.
http://www.ndif.org/Terms/pancreas.html   (222 words)

  
 Islets of Langerhans
Yet not a one made mention of "Islets of Langerhans."
But knew they not of such a place, this sublime destination.
You'll not find them on any map, your "Islets of Langerhans,"
http://www.riprense.com/Islets.htm   (334 words)

  
 Those Romantic Islets of Langerhans
Insulin is produced in the pancreas, an unattractive pancreas-shaped organ that adheres to the outside of the stomach.
On the pancreas are little spots called the islets of Langerhans, named after himself by the guy who discovered them, wouldn't you know.
People with Type I must take insulin to regulate their blood sugar.
http://www.sfgate.com/cgi-bin/article.cgi?file=/c/a/1999/02/25/DD79764.DTL&type=printable   (556 words)

  
 Endo Page 18
Islets are distinguished from the surrounding exocrine tissue by a continuous connective tissue capsule and an extensive microvascular that first bathes the center of the islet that is rich in B or beta (insulin) cells, and then the periphery where most of the A or alpha (glucagon) cells are located.
Within the islet, the glucagon-secreting alpha cells stain red while the insulin-secreting beta cells stain blue.
http://www.kumc.edu/instruction/medicine/anatomy/histoweb/endo/endo18.htm   (66 words)

  
 HLS [ Endocrine System, pancreas, islets of Langerhans] HIGH MAG labeled
HLS [ Endocrine System, pancreas, islets of Langerhans] HIGH MAG labeled
http://www.bu.edu/histology/p/10402loa.htm   (11 words)

  
 Medicine - 0521362040 - Molecular biology of the islets of Langerhans / edited by Hiroshi Okamoto. - What's Been ...
Medicine - 0521362040 - Molecular biology of the islets of Langerhans / edited by Hiroshi Okamoto.
Molecular biology of the islets of Langerhans / edited by Hiroshi Okamoto.
Print this page and give it to your librarian.
http://www.pitbossannie.com/iss-r-0521362040.html   (125 words)

  
 Islets Of Langerhans Medical Supplies and Products
Islets Of Langerhans and Medical Supplies and Products
Zappos com is proud to it offer vane Isleta (picayune Rose Does he sedate) O womans grace mule she does she fine colour.
Vaneli - Islet (Pink Pica Silk) - Women's
http://www.networksols.com/471-Islets-Of-Langerhans.html   (125 words)

  
 Human Histology Pancreas Showing Islets of Langerhans
Pancreas showing details of Islets of Langerhans from Human Histology #23
Reprint permission is granted with this footer included.*
http://www.indigo.com/software/gphpcd/his23.html   (48 words)

  
 Pancreas Functions - Hormones - Islets of Langerhans
In addition, the pancreas plays an important role in food digestion, secreting enzymes that break down fat, starch and proteins in the small intestine (duodenum).
Pancreas Functions - Hormones - Islets of Langerhans
The pancreas is a small gland (weighing less than 8oz) located close to the stomach.
http://www.carbs-information.com/pancreas-insulin-glucagon.htm   (448 words)

  
 Energy Citations Database (ECD) - Energy and Energy-Related Bibliographic Citations
Availability information may be found in the Availability, Publisher, Research Organization, Resource Relation and/or Author (affiliation information) fields and/or via the "Full-text Availability" link.
Energy Citations Database (ECD) Document #5607956 - Synthesis of glycosaminoglycans by islets of Langerhans
http://www.osti.gov/energycitations/product.biblio.jsp?osti_id=5607956   (96 words)

  
 Images with Islets of Langerhans
Islets (small islands) are one tissue type (endocrine) surrounded by another (exocrine).
An island (geographic) is a body of land surrounded by water.
The islets produce polypeptide hormones, notably insulin and glucagon.
http://www.med.uiuc.edu/histo/small/atlas/objects/862.htm   (32 words)

  
 JayceLand's Weekly Rochester Events #154: I Hear the Islets of Langerhans are Warm This Time of Year
Paul Langerhans was born 154 years ago in 1847 and discovered the islets of Langerhans on the pancreas which secrete insulin and glucagon.
What does HitsLink.com have to do with JayceLand.com?
JayceLand's Weekly Rochester Events #154: I Hear the Islets of Langerhans are Warm This Time of Year
http://www.jayceland.com/LunchNStuff/Archives/2001C20.html   (1238 words)

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