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Topic: Interferon



  
 Interferon
The studies summarized have shown that therapy of condylomata acuminata with interferon is effective.
The purpose of this study was to evaluate adjuvant drug therapies combined with standard laser excision in the treatment of recurrent respiratory papillomatosis.
It would seem that if one's situation dictates interferon as the therapy of choice and a particular brand is ineffective or has become ineffective it would make sense to switch brands.
http://www.rrpf.org/rrpf/therapies/Interferon.htm   (5137 words)

  
 Interferon Treatment for Hepatitis C
The differences in response to interferon therapy which occur as a result of viral differences are critical to clinical research in therapeutics.
The first trial of interferon as therapy for chronic non-A, non-B hepatitis was reported in 1986.
Preliminary experience with alpha-2b interferon therapy of viral hepatitis in liver allograft recipients.
http://www.interferon.ws/interferon-treatment.htm   (3893 words)

  
 interferon - drug class, medical uses, medication side effects, and drug interactions by MedicineNet.com
Interferon alfa-n3 (Alferon-N) is approved for the treatment of genital and perianal warts caused by human papillomavirus (HPV).
Therefore, all patients receiving treatment with an interferon should be observed for the development of depression and suicidal thoughts.
Interferon alfa-2a and interferon alfa-2b may increase the time it takes for theophylline (e.g., THEO-DUR) to be eliminated from the body.
http://www.medicinenet.com/interferon/article.htm   (1156 words)

  
 MedlinePlus Drug Information: Interferons, Alpha (Systemic)
Alpha interferons may also be used for other conditions as determined by your doctor.
Also, when alpha interferon is used for genital warts, very little of it gets into the rest of the body, so side effects are generally less common than in other conditions.
Children—There is no specific information comparing use of alpha interferon for cancer or genital warts in children with use in other age groups.
http://www.nlm.nih.gov/medlineplus/druginfo/uspdi/202299.html   (1786 words)

  
 PharmaCare - HCV Medication pegylated interferon (PEG-Intron)
Therefore, standard interferon plus ribavirin may be an effective therapeutic option for individuals with genotypes 2 or 3.
Overall, clinical studies have found that pegylated interferon used in combination with ribavirin (Rebetol®, Copegus®) is more effective than standard interferon in combination with ribavirin or pegylated interferon used alone.
This means that the pegylated interferon stays in the body longer and is able to fight off the HCV virus more effectively.
http://www.stadtlander.com/content/hepc/clinical/pegylated.html   (567 words)

  
 Interferon and Ribavirin Treatment Side Effects
Interferon therapy can be associated with changes in thyroid function, with both hypothyroidism and hyperthyroidism occurring.
Depression develops in 20-35% of patients treated with interferon and ribavirin.
For any symptomatic chest pain that develops during therapy, a clinician should be involved in assessing whether the chest pain could be cardiac in origin.
http://hepatitis.va.gov/vahep?page=tp06-cs-01   (2407 words)

  
 Interferon
Fentiman, I.S., Thomas, B.S., Balkwill, F.R., Rubens, r.D., and Hayward, J.L. Primary hypothyroidism associated with interferon therapy of breast cancer, Lancet 1(8438):1166.
Thus, the goal of treatment is to reduce circulating levels of interferon response back to the normal range.
Sonnenblick, M. And Rosin, A. Cardiotoxicity of Interferon - A Review of 44 Cases, Chest 99(3):557-561.
http://www.he.net/~altonweb/cs/downsyndrome/interferon.html   (2101 words)

  
 Interferon Treatment for Melanoma
"Adjuvant" Interferon means Interferon being given to try and prevent the melanoma from returning when there are no physical signs of disease present.
You will be taught how to administer the Interferon by our clinic staff.
You will be given a prescription for an anti-nausea medication and are encouraged to use it, if needed.
http://www.cancer.med.umich.edu/learn/onmelint.htm   (976 words)

  
 gihealth.com - built for patient satisfaction
This drug was developed in response to the rapid breakdown, fall in blood levels, and subsequent loss of antiviral effect seen with interferon given 3 times per week.
In the process, it may cause some side effects such as achy sore muscles and joint pain that we associate with the flu.
By attaching a molecule called P.E.G to Interferon-alpha 2a or 2b, researchers were able to slow its breakdown by the body.
http://www.gihealth.com/html/education/interferon.html   (1361 words)

  
 Boot's Story Part 2: What is Interferon and What Does It Do?
Interferon Half Life - Section on Induction Therapy asserts half life of IFN is 7-8 hours.
Interferon Therapy & Feline Herpes Virus Skin Conditions - This is a big file that loads in Acrobat Reader and takes several minutes to load.
Vets told their clients it was toxic, didn't work, hadn't had much positive response in human cancer treatments, had side effects, warned against developing an immunity to it.
http://www.geocities.com/Heartland/Pointe/9352/interferon.html   (4161 words)

  
 What is Interferon?
The Interferon- therapy gives the infected at least a chance of 20% that the virus will be killed, and helps on the other hand stabilizing the liver.
For many years the supply of human interferon for research was limited by costly extraction techniques.
I am no doctor or expert, I know little about that Interferon yet, but it seems to be the final natural viruskiller in every healthy human.
http://hepatitis-c.de/whatinf.htm   (868 words)

  
 HON: Hepatitis B V4.1 - Interferon
Interferon's occur naturally in the body and are part of the bodies natural defence system against infection.
You may wish to discus with your doctor taking N-Acetyl-Cysteine as it may improve your chance of response.
However more research needs to be done to determine if there is a long-term benefit in doing this.
http://www.hon.ch/Library/Theme/HepB/inf.html   (1848 words)

  
 Interferon definition - Hepatitis C health and medical information produced by doctors
The goal of interferon therapy is to eradicate a virus from an infected person.
interferon - Describes the medication interferon (Roferon-A, Intron-A, Rebetron, Alferon-N, Peg-Intron, Avonex, Betaseron, Infergen, Actimmune, Pegasys), a drug used in managing many diseases that involve the immune system.
Our Interferon Main Article provides a comprehensive look at the who, what, when and how of Interferon
http://www.medterms.com/script/main/art.asp?articlekey=3992   (474 words)

  
 AASLD: Consensus Interferon Plus Ribavirin Gives HCV Patients Second Chance - CME Teaching Brief - MedPage Today
In an all-comers study of patients with any HCV genotype who were non-responders or relapsers on pegylated interferon (peg-IFN) plus ribavirin therapy, the Dallas researchers found that following therapy with consensus interferon plus weight-based ribavirin, 65% of non-responders and 95% of relapsers had early virologic response rates.
Early Viral Response to Consensus Interferon plus Ribavirin Therapy in Patients who are Nonresponders or Relapsers to Prior PEG IFN plus Ribavirin Therapy.
In the Methodist study, the researchers conducted a retrospective analysis of patients who were being treated at their clinic, or had been treated there previously, with consensus interferon plus ribavirin.
http://www.medpagetoday.com/InfectiousDisease/Hepatitis/tb/2157   (880 words)

  
 Peg Intron and Interferon : Houston Indymedia
I have been doing this partly by relaying to you what I have read and researched over the years, but mostly by relating to you my personal experience with the drug, and the experiences of my friends and customers.
Health-Related Quality of Life Scores were not improved in any of the interferon treatment groups either during or after treatment.
Regarding the safety of PEG-Intron, the researchers concluded again and again that the types of "adverse events" reported were similar to those associated with Interferon.
http://houston.indymedia.org/mail.php?id=11401   (3918 words)

  
 Melanoma Center - Staging and Treatment - Interferon
These results led to the U.S. Food and Drug Administration approval of interferon alfa-2b as adjuvant therapy for melanoma in 1996.
The induction phase generally involves five days of interferon therapy per week for a four-week period.
For more information about some other adjuvant therapies in clinical trial, see the section, Experimental Therapy.
http://www.melanomacenter.org/staging/types/interferon.html   (759 words)

  
 Interferon and Down Syndrome
Interferon therapy has been associated with various cardiotoxicities including arrhythmia and congestive heart failure.
This maternal anti-interferon treatment was found to provide measurable benefit to the development and growth of the trisomic fetuses with significant return-toward-normal values observed for overall fetal growth, eye opening, and back curvature.
(This was before serum markers could prove exposure or non-exposure to hep A.) If a woman over 35 years of age had an oocyte sensitive to interferon,and there was an antiviral response in her body at the time of meiosis, the interferon could produce non-disjunction in the oocyte, leading to trisomy 21.
http://www.ds-health.com/ifn.htm   (1871 words)

  
 MedlinePlus Drug Information: Interferon Alfa-2a and Alfa-2b Injection
Your health care provider may tell you to stop your infusion if you have a mechanical problem (such as a blockage in the tubing, needle, or catheter); if you have to stop an infusion, call your health care provider immediately so your therapy can continue.
tell your doctor and pharmacist if you are allergic to interferon alfa or any other drugs.
These effects should become less severe and less frequent as you continue your therapy.
http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a690006.html   (846 words)

  
 N101 Interferon
One preliminary trial found that adding 600 mg NAC three times per day to interferon therapy for people with chronic hepatitis C led to improvement in their conditions not seen with interferon alone.
The combination of glycyrrhizin and interferon may be more effective than interferon alone.
Pneumonitis during interferon and/or herbal drug therapy in patients with chronic active hepatitis.
http://www.n101.com/HealthNotes/HNs/Drug/Interferon.htm   (1030 words)

  
 Intron A (interferon alfa-2b)
Patients should be monitored closely with periodic clinical and laboratory evaluations.
Patients will usually respond again if given further therapy.
Less than 50% of patients with chronic hepatitis B infection are eligible for interferon therapy.
http://www.hivandhepatitis.com/hep_b/treatment/interferon.html   (777 words)

  
 Interferon
Our goal was to determine if combination low-dose BCG with interferon alfa 2B (JFN-Q) would be effective in this difficult clinical situation.
While significant response was seen in those who had had prior treatment which had failed, response rates in those who had no prior treatment was nearly doubled (30% vs 67%)
Interferon - combination therapy with low dose BCG
http://blcwebcafe.org/interferon.asp   (1586 words)

  
 Pegylated Interferon and Ribavirin-Induced Interstitial Pneumonitis With ARDS -- Abi-Nassif et al. 124 (1): 406 -- Chest
McHutchison, JG, Gordon, SC, Schiff, ER, et al Interferon alpha-2b alone or in combination with ribavirin as initial therapy for chronic hepatitis C: Hepatitis Interventional Therapy Group.
make the relationship between interferon and ARDS suggestive.
interferon therapy, other treatment options have been explored,
http://www.chestjournal.org/cgi/content/full/124/1/406   (2202 words)

  
 HepNet: Interferon Frequently Asked Questions
Your doctor encourages you to continue with your normal activities as much as possible.
Treatment consists of giving yourself needles just below the skin.
Alpha interferon is known to cause other side effects such as headaches, tiredness, decrease in appetite, joint pains.
http://www.hepnet.com/ifnqa.html   (997 words)

  
 Interferons
Interferon is normally given three times a week over a protracted period of time, depending upon the underlying condition.
Interferon is one of the older chemotherapy drugs, having been in use for many years.
It is imperative that patients relay any side effects or problems to his/her medical oncologist.
http://www.tirgan.com/interfer.htm   (144 words)

  
 Interferon alpha (IntronA®, Roferon-A®) : Cancerbackup
The doctors and nurses looking after you will monitor you closely during your treatment.
Interferon is used as a treatment for some types of cancer.
Interferon is also used to treat diseases other than cancer.
http://www.cancerbackup.org.uk/Treatments/Biologicaltherapies/Interferon   (979 words)

  
 Interferon (Roferon, Intron A)
You should keep your interferon in the fridge.
Interferon may have a harmful effect on a baby developing in the womb.
The body makes interferon as part of the immune response, when the body reacts to infection or to cancers.
http://www.cancerhelp.org.uk/help?page=4009   (1220 words)

  
 HON Allergy Glossary Interferon
Some interferons induce antiviral activity, others enhance the immune response.
A group of cytokine proteins with antiviral properties, capable of enhancing and modifying the immune response.
Interferon is released to coat uninfected cells so that they don't become infected.
http://www.hon.ch/Library/Theme/Allergy/Glossary/ifn.html   (150 words)

  
 Interferon Regulatory Factor 3 and CREB-Binding Protein/p300 Are Subunits of Double-Stranded RNA-Activated ...
Masumi, A., Wang, I-M., Lefebvre, B., Yang, X.-J., Nakatani, Y., Ozato, K. The Histone Acetylase PCAF Is a Phorbol-Ester-Inducible Coactivator of the IRF Family That Confers Enhanced Interferon Responsiveness.
genes by a pathway distinct from the interferon signal pathway.
Sharma, S., tenOever, B. R., Grandvaux, N., Zhou, G.-P., Lin, R., Hiscott, J. Triggering the Interferon Antiviral Response Through an IKK-Related Pathway.
http://mcb.asm.org/cgi/content/abstract/18/3/1359   (2615 words)

  
 Interferon - Wikipedia, the free encyclopedia
Interferon-beta (Interferon beta-1a and Interferon beta-1b) is used in the treatment and control of the neurological disorder multiple sclerosis.
Several different types of interferon are now approved for use in humans, and interferon therapy is used (in combination with chemotherapy and radiation) as a treatment for many types of systemic cancer.
The most frequent side-effects are flu-like symptoms: increased body temperature, feeling ill, fatigue, headache, muscle pain, and convulsion.
http://en.wikipedia.org/wiki/Interferon   (1390 words)

  
 Interferon beta-1a - Wikipedia, the free encyclopedia
Interferon beta-1a is a drug in the interferon family used to treat multiple sclerosis.
Rebif is a disease-modifying drug used to treat relapsing forms of multiple sclerosis and is similar to the interferon beta protein produced by the human body.
These side effects are onerous enough that many patients take Interferons (or Copaxone, the other disease-modifying therapy that is available) for six months or a couple years and then decide to drop off treatment.
http://en.wikipedia.org/wiki/Avonex   (810 words)

  
 Interferon and Ribavirin Effective in HCV-Infected Hemophiliacs
Few data are available, however, on the use of combination therapy with interferon and ribavirin in patients with inherited disorders of coagulation.
Any patients who started on interferon alone, but remained positive for HCV RNA at week 12 of therapy, was switched to receive therapy with interferon plus ribavirin.
The authors conclude, "Combination therapy for chronic hepatitis C significantly improved sustained virologic response compared with interferon monotherapy in patients with inherited disorders of coagulation.
http://www.hivandhepatitis.com/hep_c/news/103002a.html   (441 words)

  
 Interferon
One currently approved use for various types of interferon-a is in the treatment of certain cases of acute and chronic hepatitis C and chronic hepatitis B. Interferon-gamma has been used to treat a variety of disease in which macrophage activation might play an important role in recovery, eg.
Since interferons have anti-proliferative effects, they have also been used to treat certain tumors such as melanoma and Kaposi’s sarcoma.
Interferons have many other effects on gene expression, not all of which are understood.
http://pathmicro.med.sc.edu/mhunt/interferon.htm   (790 words)

  
 interferon. The Columbia Encyclopedia, Sixth Edition. 2001-05
Interferons used as drugs include alpha-interferon, for hepatitis B and C, human papillomavirus, hairy-cell leukemia, and Kaposi’s sarcoma (a cancer associated with AIDS), and beta-interferon, for multiple sclerosis.
Although they were discovered in the 1950s, the medical use of interferons was impractical until the recombinant DNA techniques of genetic engineering made it possible to mass produce them.
Interferon has also been shown to have some antitumor properties.
http://www.bartleby.com/65/in/interfron.html   (193 words)

  
 HepNet: Interferon how DOES it work?-
Interferon's cytostatic/cytotoxic, antiproliferative, antiviral and immunomodulatoryeffects may be caused by various mechanisms of action.
The mechanism of actionof interferon therefore appears to be different in each disease.
This injection site map can help you with your interferon treatment.
http://www.hepnet.com/ifnmech.html   (238 words)

  
 Welcome to Introna.com
INTRON A therapy has been approved for use in the treatment of malignant melanoma, hairy cell leukemia, chronic hepatitis B, chronic hepatitis C, condylomata acuminata, follicular (non-Hodgkin's) lymphoma, and AIDS-related Kaposi's sarcoma.
A (Interferon alfa-2b, recombinant) for Injection is an interferon used as a frontline treatment for a number of indications.
If you're reading this, it's probably because your doctor has prescribed treatment with INTRON
http://www.introna.com   (275 words)

  
 BioCarta - Charting Pathways of Life
An interaction between interferon signaling and Hsp70 may alter this mitochondrial apoptosis pathway, perhaps playing a role in interferon-mediated apoptosis of infected or transformed cells.
One chaperone that modulates interferon signaling is hTid-1, a member of the DnaJ family of chaperones and a cochaperone for the heat shock protein Hsp70, another molecular chaperone.
Molecular chaperones that modulate or alter protein folding interact with different components of the interferon signaling pathway.
http://www.biocarta.com/pathfiles/h_tidPathway.asp   (504 words)

  
 Alpha interferon definition - Medical Dictionary definitions of popular medical terms
Alpha interferon: A protein produced by the body in response to an infection.
Alpha interferon definition - Medical Dictionary definitions of popular medical terms
Please consult your healthcare provider before beginning any course of supplementation or treatment.
http://www.medterms.com/script/main/art.asp?articlekey=2183   (166 words)

  
 Interferon-{gamma} and Host Susceptibility to Tuberculosis -- Bellamy 167 (7): 946 -- American Journal of Respiratory ...
Casanova JL, Abel L. Genetic dissection of immunity to mycobacteria: the human model.
of the focus of this work has been on genes in the interferon-
is likely to be the case as a common interferon-
http://ajrccm.atsjournals.org/cgi/content/full/167/7/946   (1073 words)

  
 Pfam 20.0 : Interferon
Interferons PUBMED:3022999 are proteins which produce antiviral and antiproliferative responses in cells.
The sequence differences may possibly cause different responses to various inducers, or result in the recognition of different target cell types PUBMED:6170983.
On the basis of their sequence interferons are classified into five groups: alpha, alpha-II (or omega), beta, delta (or trophoblast).
http://pfam.wustl.edu/cgi-bin/getdesc?name=Interferon   (79 words)

  
 Interferon
It must be reemphasized that interferon is not specific.
Many, but not all, viruses induce interferon synthesis, and interferon in turn can inhibit the multiplication of many kinds of viruses.
In response to infection by a virus, various cell types secrete interferon into the extracellular fluid.
http://www.uic.edu/depts/accc/seminars/flashintro/interferon.html   (145 words)

  
 Join a Lawsuit against Schering-Plough makers of Interferon
He died on interferon Roche Laboratories pegylated interferon because the doctor did not catch the warning signs and his blood platlets dropped and dropped until they let him bleed to death.
I want to find someone to help me about my husband.
The thing about me though, is that, no matter how hard the mission, I never, ever give up!
http://www.interferon.ws/Schering-Plough_lawsuit.htm   (991 words)

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