Insulin-like growth factor - Medicow
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Topic: Insulin-like growth factor


  
 Regulation of the Growth Hormone-Insulin-Like Growth Factor I Axis in Developing and Adult Monkeys Is Affected by ...
be due to enhanced sensitivity to IGF-I negative feedback.
of IGF-I by estradiol change with the transition to adulthood.
in rats that IGF-I stimulates IGFBP-3 synthesis (42, 52) and
http://jcem.endojournals.org/cgi/content/full/83/6/2018   (7168 words)

  
 Insulin-Like Growth Factor-I Resistance -- Jain et al. 19 (5): 625 -- Endocrine Reviews
True to the somatomedin hypothesis, most of the actions of GH are mediated by IGF peptides.
IGF-I to neonatal rats who were intentionally malnourished by
IGF-I treatment of two infants with leprechaunism failed to
http://edrv.endojournals.org/cgi/content/full/19/5/625   (9806 words)

  
 Maternal and Fetal Insulin-Like Growth Factor System and Embryonic Survival During Pregnancy in Rats: Interaction ...
Hydroxyproline is a good indicator of collagen breakdown and is thereby considered to reflect the connective tissue alterations
H]thymidine in fetal rat islets (Hogg et al.
Concentrations of IGFBP were analyzed by Western ligand blot method
http://www.nutrition.org/cgi/content/full/128/12/2341   (4659 words)

  
 Insulin-Like Growth Factor I Promotes Maturation and Inhibits Apoptosis of Immature Cord Blood Monocyte-Derived ...
by IGF-I were mediated through both MEK and PI 3-kinase pathways.
MEK and PI 3-kinase pathways play very important roles in DC survival and apoptosis induced by LPS (32, 33).
These effects are mediated through both MEK and PI 3-kinase pathways but not through the IGF-I induction of TNF-
http://www.pedresearch.org/cgi/content/full/54/6/919   (4241 words)

  
 Interaction between the Insulin-like Growth Factor Family and the Integrin Receptor Family in Tissue Repair Processes . ...
1 integrin is required for IGF-I to stimulate wound healing.
Neither IGF-I nor IGFBP-1 by itself was effective
Portions of this work were presented at the 1995 Wound Healing Society Meeting in Minneapolis, MN, the 1995 Plastic Surgery
http://www.jci.org/cgi/content/full/98/11/2462   (4630 words)

  
 Insulin-like growth factor binding protein 2 (IGFBP-2) separates hypertrophic and hyperplastic effects of growth ...
RT real-time PCR analysis of IGFBP-2, IGF-I, IGF-IR, and GHR mRNA expression
a presumed inhibitor of IGF actions in various human and rodent
in GH-overexpressing mice are likely to be caused by increased
http://www.fasebj.org/cgi/content/full/16/13/1721   (6701 words)

  
 Growth Factors and Cytokines
Subsequent studies have demonstrated, however, that IGF-I has autocrine and paracrine activities in addition to the initially observed endocrine activities on bone.
family of growth factors and associated signaling pathways can be found on the Signaling by Wnts and TGFs-
Studies of human disorders as well as gene knock-out studies in mice show the prominent role for FGFs is in the development of the skeletal system and nervous system in mammals.
http://web.indstate.edu/thcme/mwking/growth-factors.html   (2547 words)

  
 Recombinant Human Growth Hormone, Insulin-like Growth Factor 1, and Combination Therapy in AIDS-Associated Wasting: A ...
This lack of a linear association between physical changes of
Effects of growth factor therapy on immunologic function and
increases with growth factor therapy (that is, collagen or skeletal
http://www.annals.org/cgi/content/full/125/11/865   (5041 words)

  
 Expression of Insulin-Like Growth Factor I Messenger Ribonucleic Acid in Developing Osteophytes in Murine Experimental ...
This evidence suggests that other factors seemed to be directly
chondrocytes, the expression of IGF-I mRNA was undetectable.
that the IGF-I produced may stimulate the expression of the IGF
http://endo.endojournals.org/cgi/content/full/140/10/4821   (4741 words)

  
 Insulin-like growth factor - Wikipedia, the free encyclopedia
Almost every cell in the human body is affected by IGF-1, especially cells in muscle, cartilage, bone, liver, kidney, nerves, skin, and lungs.
IGFs are part of a complex system that cells use to communicate with their physiologic enviornment.
While IGF-2 May be primarily fetal in action it is also essential for development and function of organs such as the brain, liver and kidney.
http://en.wikipedia.org/wiki/Insulin-like_growth_factor   (651 words)

  
 ConsumerLab.com - Review Article: Human Growth Hormone (HGH) and Insulin-like Growth Factor-1 (IGF-1) Supplements
Our comprehensive review gives you the facts you need to know.
This special Review covers the science behind human growth hormone — the controversy and HGH limitations as a non-prescription supplement.
In response to subscriber questions, we took an in-depth look into the efficacy of these products and the claims they make.
http://www.consumerlab.com/results/hgh.asp   (264 words)

  
 Insulin-like growth factor 1 - Wikipedia, the free encyclopedia
Almost every cell in the human body is affected by IGF-I, especially cells in muscle, cartilage, bone, liver, kidney, nerves, skin, and lungs.
In August, 2005, the FDA approved Increlex as replacement therapy for severe IGF-1 deficiency based on clinical trial data from 71 patients.
IGF1 has been synthesized and used in therapeutic trials for several conditions including growth failure and diabetes.
http://en.wikipedia.org/wiki/Insulin-like_growth_factor_1   (482 words)

  
 Insulin-Like Growth Factor 1 (IGF-1)
Carro E, Nuñez A, Busiguina S, Torres-Aleman I. Circulating insulin-like growth factor 1 mediates effects of exercise on the brain.
Insulin-like growth factor-1: potential for treatment of motor neuronal disorders.
Plasma insulin-like growth factor 1 and prostate cancer risk: a prospective study.
http://www.pdrhealth.com/drug_info/nmdrugprofiles/nutsupdrugs/ins_0303.shtml   (637 words)

  
 News - Higher Circulating Concentrations of Insulin-Like Growth Factor-1 and Main Binding Protein Appear Associated ...
Current Perspectives on Primary Prophylaxis and Patient Risk Factors for Venous Thromboembolism in the Cancer Patient
Higher concentrations of circulating total insulin-like growth factor (IGF)-1 appear associated with an increased risk of prostate and premenopausal breast cancers, while higher concentrations of IGF binding protein (IGFBP)-3 appear associated with premenopausal breast cancer.
Higher Circulating Concentrations of Insulin-Like Growth Factor-1 and Main Binding Protein Appear Associated with Increased Risk of Common Cancers
http://www.docguide.com/news/content.nsf/news/9DDB7D9025B4E7C485256E7F004D87B8   (556 words)

  
 Growth factor 1 - The insulin-like growth factor 1 receptor induces physiological
Both Hepatocyte Growth Factor (HGF) and Stromal-Derived Factor-1 Regulate the Metastatic Behavior of Human Rhabdomyosarcoma Cells, But Only HGF Enhances
Insulin-like growth factor 1 (IGF1) was considered a potential candidate for the treatment of heart failure.
Growth factor 1 - The insulin-like growth factor 1 receptor induces physiological
http://factor.allinfosites.com/q/factor-growth-factor-1.htm   (610 words)

  
 Insulin-Like Growth Factor I (IGF-I)
Since Sm-C is decreased with malnutrition, its concentration provides an index with which to monitor therapy for food deprivation.
Low values may be found with nonfunctioning pituitary tumors, with constitutional delay of growth and development and with anorexia nervosa.
The Sm-C level does not distinguish pituitary dwarfism from constitutional delay of growth and development.
http://www.labcorp.com/datasets/labcorp/html/chapter/mono/sr003600.htm   (506 words)

  
 ARUP: IGF-1 (Insulin-Like Growth Factor 1)
Insulin like growth factor (IGF-1, also referred to as somatomedin-C or Sm-C), is one of a class of peptides whose serum concentrations are regulated principally by human growth hormone (GH) and nutritional intake.
(See also: Growth Hormone and IGF Binding Protein-3.) In humans, two of these peptides have been identified, IGF-1 and IGF-2.
The anabolic and growth promoting effects mediated by the IGFs include cell proliferation and protein synthesis.
http://www.aruplab.com/guides/clt/tests/clt_al3b.jsp   (384 words)

  
 IGF-1, Homeopathic Proving, Insulin-like Growth Factor
Heat internally and sensation of heat of the cheeks.
Localized most frequently to the forehead, and also behind the eyes, above the root of the nose, or in the vertex.
Pain quality was pressing as from a weight or like a band.
http://www.biomedcomm.com/store/pi_igf1_proving.html   (1144 words)

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