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| | Technology Application Areas: Xenogen Corporation |
 | | Light producing animal models are also able to model disease pathways, or pathway labeling, thereby enabling researchers to determine where a drug affects a particular disease pathway, better understand the mechanism of action of a drug, and, as a result, expand the potential for discovering novel therapeutic approaches. | | | Real-time in vivo imaging can be applied to a broad range of critical drug discovery/development applications that span many therapeutic areas. | | | In addition to being inherently low-throughput, traditional animal modeling techniques are not very predictive of success in the clinic, and a high failure rate in drug development persists. |
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http://www.xenogen.com/tech.html
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| | Carcinogens, summary report on the evaluation of short-term in vivo tests (EHC 109, 1990) |
| | In vivo procedures will, therefore, be reserved for more specific applications such as investigating the activity of in vitro genotoxins in the whole animal and to assist in the assessment of the mutagenic and carcinogenic poten- tial associated with exposure of humans to in vitro geno- toxins. | | | The remaining five tests suggested a weak induction of SCE in rodent bone marrow that was not reproduced in all laboratories, a single positive host- mediated assay, and evidence of the excretion of mutagenic metabolites in rodent urine. | | | Ninety-seven investigators from sixteen countries par- ticipated in the in vivo project and data were presented from some fifty separate in vivo techniques. |
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http://www.inchem.org/documents/ehc/ehc/ehc109.htm
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| | In vivo - Wikipedia, the free encyclopedia |
| | This means that in vivo research will likely give a better indication of what will happen in a population when a compound is administered to or a procedure is performed on an animal model of disease. | | | Clinical trials are a form of in vivo research, albeit on humans. | | | For example, In vivo biological research differentiates whole organism research from in vitro research, which is performed on organs, tissues, cells, cellular components, proteins, or biomolecules. |
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http://en.wikipedia.org/wiki/In_vivo
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| | Amazon.com: In Vivo NMR Spectroscopy : Principles and Techniques: Books: Robin deGraaf |
| | Also, those who want to broaden their knowledge on the concepts of NMR, such as researchers in high-resolution NMR, neurology, physiology, chemistry, and medical biology will benefit greatly from this book. | | | The educational and practical character of this book makes it ideal for use in training courses at large research institutes and academic hospitals. | | | Covers in-depth, the technical & basic biophysical aspects of in vivo NMR Spectroscopy. |
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http://www.amazon.com/exec/obidos/tg/detail/-/0471983659?v=glance
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| | PA-04-045: IN VIVO CANCER IMAGING EXPLORATORY/DEVELOPMENTAL GRANTS |
| | In vivo cancer image displays and analyses (discovery, development, pre- clinical and initial clinical application of innovative methods in the display and analysis of in vivo cancer images); and 4. | | | In vivo image-guided cancer interventions (discovery, development, pre- clinical and initial clinical application of innovative methods for the image-guided treatment of cancer). | | | RESEARCH OBJECTIVES The potential for innovative in vivo cancer imaging applications to improve the detection and diagnosis of cancer, and alter the clinical management of cancer patients continues to expand. |
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http://grants.nih.gov/grants/guide/pa-files/PA-04-045.html
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| | Human Body Composition: In Vivo Methods -- Ellis 80 (2): 649 -- Physiological Reviews |
| | In vivo methods used to study human body composition continue to be developed, along with more advanced reference models that | | | The earliest, and still the most direct, in vivo measurement technique for TBW is that based on the dilution principle, using | | | development of in vivo neutron activation analysis (NAA) techniques. |
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http://physrev.physiology.org/cgi/content/full/80/2/649
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| | Medical in vivo NMR and Imaging |
| | We compare the results of FAIR, PRESS and previous DWI studies to evaluate the most sensitive method for monitoring early change of the excitotoxic lesions, in order to develop an efficient MR modality and a new therapeutic strategy in neurodegenerative diseases. | | | The techniques are being extended to other types of tissue and in-vivo measurements. | | | This technique has a potential to provide capabilities of physiologic imaging non invasively. |
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http://www.enc-conference.org/1998Abstracts/mni_posters.html
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| | Effect of RNA from Normal Human Bone Marrow on Leukaemic Marrow In-Vivo. |
| | While it is possible to obtain these conditions in vitro, it will probably be necessary to learn how to reproduce them in vivo before we will be able to bioassay specific proteinopoietic activities of the ribonucleic acids from different sources. | | | Effect of RNA from Normal Human Bone Marrow on Leukaemic Marrow In-Vivo. | | | "Effect of RNA from Normal Human Marrow on Leukaemic Marrow In-Vivo". |
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http://www.euchromatin.org/RNA04.htm
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| | c59 Quantitative In Vivo NMR |
| | H FID of the brain of a rat | | | P longitudinal relaxation experiment of a human brain | | | Example 7: Application of time-domain fitting techniques to in vivo |
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http://dutnsic.tn.tudelft.nl:8080/c59_to_html/c59.html
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| | PA-04-094: NOVEL TECHNOLOGIES FOR IN VIVO IMAGING (SBIR/STTR) |
| | in vivo molecular imaging) similar to that currently available from histological or micro-array techniques use for in vitro studies would be very useful. | | | Clinical trials for clinical validation of emerging imaging technologies are beyond the scope and not responsive to this PA. Studies with pre-clinical models and clinical studies to demonstrate the feasibility of developments are encouraged, including multi-site evaluations, where appropriate. | | | The interests of NCI focus on imaging in vivo for cancer pre-conditions, cancer screening, diagnosis, progression, treatment monitoring, recurrence, and image- based surrogate end points. |
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http://grants.nih.gov/grants/guide/pa-files/PA-04-094.html
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| | Light dosimetry in vivo |
| | Examples are given of in vivo measurements in animal experiments and in humans during clinical treatments. | | | Most in vivo light fluence rate measurements have been concerned with photodynamic therapy (PDT). | | | Optical properties of the same normal tissue may differ between patients. |
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http://stacks.iop.org/0031-9155/42/763
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| | in vivo Hollow Fibers |
| | Spectra/Por in vivo Microdialysis Hollow Fibers were developed for applications requiring in vivo recovery or dispensing of microquantities of biological materials within a localized section of a functioning organ. | | | A unique feature of the in vivo microdialysis technique allows the comparison of results from in vitro and in vivo experiments. | | | This concept is an artificial blood vessel implanted within the tissue, to recover substance from or add to the organ. |
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http://www.spectrapor.com/1/0/8.html
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| | FDA/CFSAN Redbook 2000 IV.C.1.d. Mammalian Erythrocyte Micronucleus Test |
| | Mavournin, K.H., Blakey, D.H., Cimino, M.C., Salamone, M.F. and Heddle, J.A. The In Vivo Micronucleus Assay in Mammalian Bone Marrow and Peripheral Blood. | | | Garriott M.L., Brunny J.D., Kindig D.E., Parton J.W., Schwier L.S. The In Vivo Rat Micronucleus Test: Integration with a 14-Day Study. | | | Except for treatment with the test substance, animals in the control groups should be handled in an identical manner to animals of the treatment groups. |
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http://vm.cfsan.fda.gov/~redbook/redivc1d.html
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| | PDx by GloboMax Products and Services |
| | Exploration of In Vitro and In Vivo Relationships | | | Provide support for a biowaiver or SUPAC submission or to aid in the formulation selection process before clinical studies. | | | In this approach, the in vitro dissolution test becomes a meaningful predictor of in vivo performance of the formuation, and dissolution specifications may be used to minimize the possibility of releasing lots that would be different in in vivo performance. |
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http://www.globomax.net/products/pdx_ivivc.cfm
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| | MMPC: In Vivo Core |
| | Mouse surgery to establish chronic cannulation of jugular vein for infusion during experiments. | | | Measurement of body fat composition in conjunction with NMR Core. | | | The In Vivo Metabolism Core at the Yale Mouse Metabolic Phenotyping Center is designed to conduct in vivo experiments and analytical assays to characterize the metabolic phenotype of transgenic/knockout mouse models potentially useful for understanding diabetes, its complications, obesity, and related metabolic disorders. |
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http://mouse.yale.edu/in_vivo.html
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| | FDA/ORA Compliance Program Guidance In Vivo Bioequivalence |
| | Specifications should be established to assure that blank biological fluids are as similar as possible to the biological matrix for the subject samples. | | | The source of the drug standards used for the in vivo sample analysis. | | | Product coding not required for biopharmaceutical analytical and clinical establishment types. |
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http://www.fda.gov/ora/compliance_ref/bimo/7348_001
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| | Research on Axon Guidance in Vivo in the Tosney lab |
| | The in vivo level of analysis shown on this page is the most basic; it defines all subsequent questions. | | | A major puzzle in development is how neurons extend to their targets with such precision. | | | To help solve this puzzle we examine axonal guidance at three levels, the in vivo level, the cellular level and the molecular level, each of which proffers its own methods and insights. |
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http://www.biology.lsa.umich.edu/research/labs/ktosney/file/Res/ResInVivo.html
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| | Amazon.com: In Vivo Neuromethods (Neuromethods): Books: Alan A. Boulton,Glen B. Baker,Alan N. Bateson |
| | During the last three decades, the necessity to measure the release of neurotransmitters in vivo in the central nervous system (CNS) has prompted the development of innovative techniques for sampling the extracellular fluid in the brain of experimental animals. | | | Be the first person to review this item. | | | Amazon.com: In Vivo Neuromethods (Neuromethods): Books: Alan A. Boulton,Glen B. Baker,Alan N. Bateson |
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http://www.amazon.com/exec/obidos/tg/detail/-/0896035115?v=glance
(440 words)
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| | CLONTECHniques Jul 99 - Mercury(TM) In Vivo Kinase Assay Kits |
| | This built-in negative control helps you eliminate experimental variability. | | | The foundation of each kit is a transactivator expression vector specific for a given pathway. | | | These vectors provide a handy way to study the effects of these kinases on each of the four pathways. |
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http://www.clontech.com/archive/JUL99UPD/MercuryKinase.shtml
(980 words)
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| | NCIDEA: Imaging Sciences Working Group: In Vivo Molecular Imaging Subgroup |
| | Create a mechanism to fund the chemical synthesis of contrast agents for use by researchers in the clinical and basic research settings. | | | Develop image processing and analysis techniques for high-throughput, automated screening of whole animal/organ scans. | | | Integrate the in vivo imaging techniques with in vitro and ex vivo imaging techniques, including gene expression maps. |
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http://deainfo.nci.nih.gov/ADVISORY/pog/directors/img_sci/moleimaging.htm
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| | In vivo transfection |
| | Based on a lipid composition of DOTAP/cholesterol, well characterized for in vivo transfection experiments, all formulations include a fluorophore which enables the distribution of the lipids in the tissues to be directly visualized. | | | This in vivo formulation acts the same way as classical jetPEI™. | | | Megafectin™ in vivo transfection reagents represent a new generation of liposomal transfection reagents. |
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http://www.qbiogene.com/products/transfection/app-invivo.shtml
(185 words)
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| | ::In Vivo Dosimetry:: |
| | Due to the rapid development of advanced treatment techniques and planning, the demand for in vivo dosimetry is increasing. | | | Many clinics have been or are working towards an ISO certification, and one important tool is to ensure that the dose delivery is accurate. | | | In vivo dosimetry therefore is an essential element in the quality assurance of today's radiotherapy department. |
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http://www.scanditronix-wellhofer.com/index.php?id=430
(136 words)
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| | In Vivo Use of Antibodies |
| | Studies in the mouse model using both in vitro and in vivo assays have resulted in better understanding of the immune function and the role of different cell types in the immune response. | | | Experiments performed in a living laboratory mouse, however, provide information about the direct biological relevance, collaboration, and interdependence of complex biological processes, many of which may not be well understood. | | | Users are encouraged to review these papers and other sources in the literature to find the optimal protocol and dosage they need in their experiments. |
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http://www.ebioscience.com/ebioscience/appls/invivo.htm
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| | In Vivo Data and Tamiflu Pandemic Containment Myth |
| | However, the amount of Tamiflu ordered was based on the assumption that a course of 10 pills would be effective for 10 days of prevention or 5 days of treatment. | | | However, this assumption was not supported by in vitro data and now is also not supported by in vivo data. | | | Influenza A codes for nine NA serotypes and Tamiflu had been previously tested against all nine, using two representative viruses for each. |
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http://www.recombinomics.com/News/07180501/H5N1_In_Vivo_Tamiflu.html
(707 words)
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| | in-vivo/in-vitro correlation - Dissolution Discussion Group Bulletin Board |
| | Unfortunately, the in-vivo testing does not correlate and is more problematic. | | | Although this looked promising, in-vivo data generated since this method change has not correlated. | | | I suspect that there is more going on here than just the dissolution method itself, but since I have no control over manufacturing, I must work with what I have. |
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http://www.dissolution.com/vbulletin/showthread.php?s=&postid=3007
(626 words)
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| | Mathematical Analysis of HIV-1 Dynamics in Vivo |
| | By comparing these models to data obtained from patients undergoing antiretroviral drug therapy, it has been possible to determine many quantitative features of the interaction between HIV-1, the virus that causes AIDS, and the cells that are infected by the virus. | | | Mathematical Analysis of HIV-1 Dynamics in Vivo: SIAM Review Vol. | | | Mathematical models have proven valuable in understanding the dynamics of HIV-1 infection in vivo. |
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http://epubs.siam.org/sam-bin/dbq/article/33510
(182 words)
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| | TransIT In Vivo Gene Delivery System |
| | Purchase of this product does not provide a license to this delivery technology, which is required for all research and commercial uses by for-profit entities. | | | The TransIT® In Vivo Gene Delivery System is the first set of reagents designed specifically to introduce nucleic acids into live mice, allowing for organ-specific genetic studies that were previously impossible to perform on a routine basis. | | | Highest gene expression is found in the liver with lower levels in the spleen, lung, heart and kidneys. |
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http://www.mirusbio.com/products/transit/invivo/index.asp
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| | Citebase - Protein crystallization in vivo |
| | * One of the clearest examples of in vivo crystallization causing disease. | | | One of the most recent examples of protein crystallization in vivo in the biology literature | | | Use the Correlation Generator to explore the correlation between download impact ("hits") and citation impact. |
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http://citebase.eprints.org/cgi-bin/citations?id=oai:arXiv.org:q-bio/0510006
(1481 words)
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| | Deltagen Target Discovery and Validation In Vivo Technology |
| | Deltagen has industrialized a revolutionary in vivo technology platform for the large-scale generation of functional information on genes related to key areas of drug discovery. | | | Using a preferred, targeted mutagenesis process, our scientists can delete—or “knock out”—precise genes in mouse models and then utilize an extensive phenotypic analysis program to determine the specific function and potential pharmaceutical relevance of these genes and the proteins they encode. | | | The proprietary technology platform has been validated through collaborations with some of the world’s leading pharmaceutical companies, including Pfizer Inc., GlaxoSmithKline plc, and Merck and Co., Inc., as well as with internationally recognized research institutions such as Stanford University. |
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http://www.deltagen.com/target/invivo.html
(114 words)
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| | NewScientistJobs.com - Job details - Scientist, In Vivo Biology - Rinat Neuroscience - S San Francisco - US California |
| | Rinat Neuroscience, a young, growing company in the San Francisco Bay Area, is a pioneer in developing and commercializing protein based therapeutics for diseases and disorders of the nervous system and aims to build on this position to become a leading neuroscience-based biopharmaceutical company. | | | Rinat is seeking an independent, experienced Scientist to initiate, direct and execute all aspects of in vivo biology. | | | We currently have a great opportunity for an experienced Scientist, In Vivo Biology to join our team. |
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http://www.newscientistjobs.com/viewjob.action?job.id=scij14425
(377 words)
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| | IN VIVO - Reviews |
| | Under the name of In Vivo their album has returned to Australia via their signing to the LA based Birdcage label which in turn is distributed here by TWA through their association with Birdcage co-founder Stan Ridgway. | | | Look out for In Vivo and their self-titled album. | | | It's an odd way to go about releasing an album in your home country, but no one seems to be complaining - neither should we. |
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http://www.birdcagerecords.com/iv_rev.html
(1301 words)
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| | In vivo jetPEI |
| | The mode of action of in vivo jetPEI™ is particularly well-adapted to in vivo transfection since, in contrast with lipid-based reagents, cell membrane permeabilization is avoided. | | | Improved manufacturing and purification techniques for L-PEI have enabled the introduction of a more effective reagent, in vivo-jetPEI™, that shows superior lot-to-lot reproducibility with lowest residual toxicity. | | | It has been shown to successfully transfect cells in various types of tissue following intravenous |
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http://www.qbiogene.com/products/transfection/jetpei/invivo.shtml
(516 words)
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| | "In vivo" Spam Filtering: A challenge problem for data mining (ResearchIndex) |
| | Many data mining researchers have addressed the problem of detecting spam, generally by treating it as a static text classification problem. | | | Abstract: Spam, also known as Unsolicited Commercial Email (UCE), is the bane of email communication. | | | Online articles have much greater impact More about CiteSeer.IST Add search form to your site Submit documents Feedback |
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http://citeseer.ist.psu.edu/638871.html
(591 words)
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| | In-Vivo |
| | In Vivo Measurement of Articular Surfaces and other Internal Landmarks | | | Follow a simple 4 step process to quickly reference internal landmarks from multiple x-rays and fluoroscopes to the coordinate system of surface mounted 6dof tracking sensors. |
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http://www.innsport.com/MMRin-vivoNONAV.htm
(169 words)
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| | In Vivo Carbon-13 Nmr - Compare Prices & Reviews at Smarter |
| | Home > Books > Science > Life Sciences / Biochemistry > In Vivo Carbon-13 Nmr | | | Your use of this Web site constitutes acceptance of the Smarter.com Privacy Policy and Terms & Conditions | | | In Vivo Carbon-13 Nmr - Compare Prices & Reviews at Smarter |
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http://www.smarter.com/books-1/product/in_vivo_carbon-13_nmr-846864
(212 words)
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| | Tracking Nanomaterials In Vivo |
| | By studying various nanostructures, the investigators were able to determine how to maximize the MRI signal with a minimum amount of gadolinium, which can be toxic in large amounts. | | | Stupp and his team are now using this gadolinium-containing amino acid to study degradation and migration of their self-assembled nanostructures in vivo. | | | This work is detailed in a paper titled, “Magnetic resonance imaging of self-assembled biomaterial scaffolds,” which appeared in the journal Bioconjugate Chemistry. |
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http://www.physorg.com/news9346.html
(519 words)
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| | Energy Citations Database (ECD) - Energy and Energy-Related Bibliographic Citations |
| | Availability information may be found in the Availability, Publisher, Research Organization, Resource Relation and/or Author (affiliation information) fields and/or via the "Full-text Availability" link. | | | Energy Citations Database (ECD) Document #6708035 - Lymphotoxin prevention of diethylnitrosamine carcinogenesis in vivo |
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http://www.osti.gov/energycitations/product.biblio.jsp?osti_id=6708035
(105 words)
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| | In Vivo Metric Biomedical Products: Electrodes, Electrode Accessories, Patient Cables, Leadwires, Vascular Occluders, ... |
| | In Vivo Metric Biomedical Products: Electrodes, Electrode Accessories, Patient Cables, Leadwires, Vascular Occluders, since 1965 | | | In Vivo Metric's Vascular Occluders are reusable inflatable silicone rubber cuffs for the constriction of blood vessels (arteries and veins) and soft organs for zero blood flow determination. | | | Electrode Accessories: Patient cables, snap and pinch leadwires, skin preps and gels, electrode washers (adhesive discs/collars), conductive gels, medical/surgical tapes and wraps. |
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http://www.invivometric.com
(161 words)
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| | Windhover Information Inc. |
| | In Vivo, Start-Up, and In-Vivo Europe from 1995 to Present. | | | Order your copy today in Print and/or CD! | | | Receive Windhover's unique market insight fast with our free alert service 'Windhover's Update', for the latest abstracts and executive summaries from: |
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http://www.windhover.com
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