|
| |
| | The Biological Notion of Self and Non-self |
 | | It was at this juncture that Sir Frank Macfarlane Burnet formally introduced the “self” into the immunological lexicon, and upon that metaphor erected a theory of immunological tolerance that was to henceforth dominate the field (Burnet and Fenner 1949; Tauber 1994). | | | It was at this juncture that Sir Frank Macfarlane Burnet introduced the “self” into the immunological lexicon (Burnet and Fenner 1949), and upon that metaphor erected a theory of immunological tolerance that still dominates the field. | | | Burnet's theory proposed that the animal, during prenatal development, exercised a purging function of self-reactive lymphocytes (the cells responsible for synthesizing reactive antibodies and mediating so-called cellular reactions) so that all antigens (substances that initiate immune responses) encountered during this period would attain a neutrality status. |
|
http://setis.library.usyd.edu.au/stanford/entries/biology-self
(3852 words)
|
|
| |
| | IEG - Institute of Experimental Genetics - Genome Project |
| | Moreover, recent studies indicate that the Delta/Notch pathway belongs to a sophisticated system of interactions, which is believed to be involved in a wide range of common diseases including cancer, immunological diseases, infections as well as cardiovascular and neurological diseases. | | | A screening and phenotyping protocol for pathophysiological abnormalities – the Munich protocol – has been established in the last years to assess mutant phenotypes for specific, postnatal abnormalities comprising congenital malformations, clinical chemical, biochemical, immunological defects and complex traits like allergy and behaviour. | | | The F1 animals generated are screened for dysmorphological, clinical chemistry and immunological variations, measuring the parameters indicated previously. |
|
http://www0.gsf.de/ieg/groups/genome/enu.html
(1651 words)
|
|
| |
| | Dentists on Mars |
| | She will then discuss her research on cell cultures of osteoblasts in space, and in hypergravity Dr. Gerald Sonnenfeld will review immunological changes that occur in spaceflight, and relate the observed decreases in various types of immunological responses to possible effects on oral immunological factors. | | | Dr. Millie Hughes-Fulford, an astronaut-scientist, will review what happens to humans who go into space, and the difficulties of living, and carrying out experiments in space. | | | The objective of this symposium is to introduce the dental research community to changes occurring in humans who go into space, and how these changes might impact oral health. |
|
http://iadr.confex.com/iadr/2004Hawaii/techprogram/session_8836.htm
(322 words)
|
|
| |
| | Sir Peter B. Medawar -- Encyclopædia Britannica |
| | Medawar, Sir Peter B. Brazilian-born British zoologist who received with Sir Frank Macfarlane Burnet the Nobel Prize for Physiology or Medicine in 1960 for developing and proving the theory of acquired immunological tolerance, a model that paved the way for successful organ and tissue transplantation. | | | in full Sir Peter Brian Medawar Brazilian-born British zoologist who received with Sir Frank Macfarlane Burnet the Nobel Prize for Physiology or Medicine in 1960 for developing and proving the theory of acquired immunological tolerance, a model that paved the way for successful organ and tissue transplantation. | | | Biography of this British scientist awarded the Nobel Prize in Medicine or Physiology, in 1960, for the discovery of acquired immunological tolerance. |
|
http://www.britannica.com/eb/article-9051717
(694 words)
|
|
| |
| | How Matol Biomune OSF Plus Works |
| | Other immunological factors - There are other obscure but critical immunological components identified and unidentified that provide a synergistic relationship to create immunological responses that enhance immune function. | | | It is safe in organ transplant patients as the rejection mechanism is not affected by the mechanism of operation of the Matol Biomune OSF Plus. | | | If the immune system is overactive as in autoimmune diseases (lupus, arthritis, allergies, MS etc.) it will be down-regulated and if it is underactive or depressed it will be up-regulated. |
|
http://www.goode-health.com/tphowworks.htm
(694 words)
|
|
| |
| | Burnet, Sir Macfarlane -- Encyclopædia Britannica |
| | Medawar, Sir Peter B. Brazilian-born British zoologist who received with Sir Frank Macfarlane Burnet the Nobel Prize for Physiology or Medicine in 1960 for developing and proving the theory of acquired immunological tolerance, a model that paved the way for successful organ and tissue transplantation. | | | The cowinner (with Peter Medawar) of the 1960 Nobel prize for physiology or medicine, Macfarlane Burnet was noted for his role in the discovery of acquired immunological tolerance to tissue transplants. | | | in full Sir Frank Macfarlane Burnet Australian physician, immunologist, and virologist who, with Sir Peter Medawar, was awarded the 1960 Nobel Prize for Physiology or Medicine for the discovery of acquired immunological tolerance, the concept on which tissue transplantation is founded. |
|
http://www.britannica.com/eb/article-9018195
(694 words)
|
|
| |
| | CBER - Simian Virus 40 (SV40:) A Possible Human Polyomavirus Workshop |
| | A virus infection is probably controlled by tight immunological surveillance, and the severe changes of immunological virus/host interaction and probably comes to a 2-step situation. | | | This brings us back to the third possibility that changes in the virus host interactions due to severe breakdown of the immunological surveillance are the real requirement for the induction of clinical, overt CNS disease. | | | And the first NIH grant that I obtained was to study if simian virus 40 was responsible for any human cancers in India. |
|
http://www.fda.gov/CbER/minutes/sv40012797-1.htm
(694 words)
|
|
| |
| | CBER - Simian Virus 40 (SV40:) A Possible Human Polyomavirus Workshop |
| | A virus infection is probably controlled by tight immunological surveillance, and the severe changes of immunological virus/host interaction and probably comes to a 2-step situation. | | | This brings us back to the third possibility that changes in the virus host interactions due to severe breakdown of the immunological surveillance are the real requirement for the induction of clinical, overt CNS disease. | | | This slide just demonstrates that the JC virus is not another SV40 or humana SV40, and it has its own personality and character. |
|
http://www.fda.gov/cber/minutes/sv40012797-1.htm
(21092 words)
|
|
| |
| | Nutrition Journal Full text Different degrees of malnutrition and immunological alterations according to the aetiology of cirrhosis: a prospective and sequential study |
| | To assess both nutritional and immunological alterations in HCV related cirrhotic patients in comparison to alcoholic cirrhosis and evaluate the alcohol and HCV associated group that is very frequent in the clinical practice were the main objectives of this study. | | | Significant differences were found among the main aetiologies of cirrhosis concerning immunological alterations and nutritional status: better nutrition and worse immunology for HCV and vice-versa for alcohol. | | | Similarly to the nutritional evaluation, the immunological parameters in the course of cirrhosis were preferentially evaluated in alcoholic aetiology [ 2, 12, 32-34 ]. |
|
http://www.nutritionj.com/content/2/1/10
(21092 words)
|
|
| |
| | Chemical and immunological studies of cell surfaces from normal and transformed cells. |
| | Chemical and immunological studies of cell surfaces from normal and transformed cells. | | | Immunological and chemical studies of cell surfaces from normal and transformed BALB/c fibroblasts have shown alterations associated with transformation. | | | Chemical and immunological studies of cell surfaces from normal and transformed cells.Results from these studies do not show changes associated with malignancy. |
|
http://www.pdg.cnb.uam.es/UniPub/iHOP/gp/2909114.html
(236 words)
|
|
| |
| | Reagent for detecting non-A, non-B viral hepatitis (NANBH) and an immunoenzymatic method for detecting NANBH antigens in fecal extracts - Patent 4871659 |
| | with a fecal extract from a human to be diagnosed, to thereby form an immunological complex; | | | The reagent is useful for diagnosing epidemic NANB viral hepatitis by forming an immunological complex between the anti-NANBH IgM and antigen in a fecal extract from a patient being diagnosed, and then incubating the immunological complex with enzyme-labeled IgG from serum of a human convalescing from epidemic NANBH. | | | According to the invention, IgM's isolated from sera of infected mammals make it possible to perform tests for diagnosing NANB hepatitis by immunoenzymatic characterization of an antigen associated with NANBH virus present in the feces of patients suffering from an epidemic form of NANB hepatitis. |
|
http://www.freepatentsonline.com/4871659.html
(2813 words)
|
|
| |
| | Automated immunoassay analyser - Patent 5055408 |
| | Therefore, in automatizing these test systems, the constitution and assembly of the apparatus must be adapted to the particular properties of the respective immunological reactions and the labels, and furthermore convenience in practical use and the cost of operation should also be taken into consideration. | | | Processes for immunological procedures are different for different labels; thus, they include FIA using a chemical fluorescent material, RIA using a radioactive substance and EIA using an enzyme, each as the label. | | | Possibility of human errors due to different operators and an insufficient number of operators for the rapidly increasing number of samples to be tested has accelerated the need for automatizing the test apparatus for immunological reactions. |
|
http://www.freepatentsonline.com/5055408.html
(4707 words)
|
|
| |
| | Publications: Alain de Weck |
| | Frey, Johann R., de Weck, Alain Ladislas, and Geleick, H. Sensitization, immunological tolerance, and desensitization of guinea pigs to neoarsphenamine. | | | Frey, Johann R., de Weck, Alain Ladislas, and Geleick, H. Sensitization, immunological tolerance and desensitization of guinea pigs to neoarsphenamine. | | | Frey, Johann R., de Weck, Alain Ladislas, and Geleick, H. Sensitization, immunological tolerance, and desensitization of guinea pigs to neoarsphenamine (NEO). |
|
http://www.weck.ch/public_section/Alain_230.htm
(8750 words)
|
|
| |
| | Tetracore: Rabbit Anti-Francisella tularensis IgG |
| | It can be labeled with biotin, colloidal gold, or other similar labels for immunological based assays. | | | This antibody can be used in a variety of immunological assays for the detection and quantification of vegetative cells of Francisella tularensis. | | | tularensis antibody reacts with vegetative cells of Francisella tularensis. |
|
http://www.tetracore.com/products/antibody/TC_7005.html
(8750 words)
|
|
| |
| | Immunological characterizations of a cloned 13.1-kilodalton protein from pathogenic Naegleria fowleri. |
| | Immunological characterizations of a cloned 13.1-kilodalton protein from pathogenic Naegleria fowleri. | | | Immunological characterizations of a cloned 13.1-kilodalton protein from pathogenic Naegleria fowleri.Trophozoites of N. fowleri in cultivation reacted strongly with a peroxidase-labeled anti-Nfa1 antibody. | | | In this study, to get more information regarding the recombinant Nfa1 protein (rNfa1), we produced an anti-Nfa1 polyclonal antibody from mice immunized with rNfa1 and used a peroxidase staining method to carry out immunocytochemistry experiments. |
|
http://www.pdg.cnb.uam.es/UniPub/iHOP/gp/10137331.html
(241 words)
|
|
| |
| | [Immune status of adult population of the Bryansk region living in territory polluted by radionuclides] |
| | Clinical and immunological investigation with immune status evaluation of three groups of adult population of Bryansk Region was performed. | | | The second group included 68 persons living in Vyshkov, immunological monitoring of those was performed. | | | The first group included 165 persons living in Vyshkov (settlement of town type in Bryansk Region) contaminated with radionuclides as a result of Chernobyl accident. |
|
http://www.aegis.com/aidsline/1995/jul/M9570258.html
(463 words)
|
|
| |
| | GAMMA is specialized in immunological techniques for in vitro medical diagnostic use |
| | GAMMA is specialized in immunological techniques for in vitro medical diagnostic use | | | The company is specialized in immunological techniques for in vitro medical diagnostic use. | | | Founded in 1983, GAMMA has privileged access to the University of Liège and is active in technology transfer from research laboratories to commercial applications. |
|
http://www.gamma.be
(116 words)
|
|
| |
| | Lecture 11: Immune System and Lymphoid Organs |
| | B lymphocytes in superficial cortex; associated with predominantly humoral immunological response | | | T lymphocytes in paracortical region never arranged as follicles; associated with predominantly cytotoxic immunological response | | | T lymphocytes = vast majority in circulation, periarteriolar, medullary portions of lymphnodes and spleen. |
|
http://www.pitt.edu/~sshostak/biosci1450/hislec11.html
(116 words)
|
|
| |
| | vaccine.asp?pg=2 |
| | Issels was a leading pioneer of the immunological and microbiological approach to cancer and at the forefront of holistic integrative cancer medicine. | | | Josef Issels pursued research on immunological and microbiological aspects of cancer etiology since 1948. | | | Issels has used ultraviolet blood irradiation therapy, not only with T-cell lymphoma, but with all types of cancer. |
|
http://www.issels.com/vaccine.asp?pg=2
(1992 words)
|
|
| |
| | Cancer Treatment and Autologous Immunotherapy |
| | Although cancer does not seem to be a pure immunological deficiency disease, surgeons should always be obliged to secure ample sterile amounts of the patient’s tumour, as well as metastases which carry his own 'fingerprint' of different tumour cell markers. | | | Since the clinical behaviour of melanoma indicates that this form of cancer is particularly responsive to immunological forms of treatment, and because conservative treatment modalities have fairly little impact on the disease, patients suffering from metastasised malignant cutaneous melanoma were treated using bio-immunotherapy, starting over 23 years ago. | | | With the ever-increasing incidence of cancer, our general medical health care is faced with the threat that national economies will soon not be able to cope with the expense of acceptable treatment modalities for cancer. |
|
http://www.acnem.org/journal/15-1_april_1996/cancer_treatment_and_autologous_immunotherapy.htm
(1992 words)
|
|
| |
| | The lymphocyte in immunology: from James B. Murphy to James L. Gowans - Nature Immunology |
| | Between 1911 and 1926, James B. Murphy, an experimental pathologist working at the Rockefeller Institute, performed a series of remarkable experiments that appeared to prove beyond question that the lymphocyte is the active participant in the rejection of tissue allografts, in protection against infection and, by implication, in both innate and acquired immunological responses. | | | The work on transplantable tumors at the Imperial Cancer Research Fund in London, Paul Ehrlich's Institute in Frankfurt and elsewhere had shown that the rejection of tumor grafts and of grafts of normal tissues was an immunological phenomenon. | | | Murphy finished medical school at Johns Hopkins in 1909 and, with the urging of Florence Sabin, accepted a position to do cancer research at the Rockefeller Institute for Medical Research under fellow Hopkins alumnus, pathologist Peyton Rous. |
|
http://www.nature.com/cgi-taf/DynaPage.taf?file=/ni/journal/v2/n7/full/ni0701_569.html
(3194 words)
|
|
| |
| | Online Mendelian Inheritance in Man ‘OMIM’ Amladi S - Indian J Dermatol Venereol Leprol |
| | Genodermatoses, genetic syndromes, inherited skin diseases and also inflammatory or immunological disorders with a genetic basis occupy an important part of the dermatology curriculum. | | | Immunological or inflammatory disorders with a polygenic inheritance such as atopic dermatitis, psoriasis, alopecia areata and lichen sclerosus are also included. | | | McKusick-Nathans Institute for Genetic Medicine, Johns Hopkins University (Baltimore, MD) and National Center for Biotechnology Information, National Library of Medicine (Bethesda, MD), 2000. |
|
http://www.ijdvl.com/article.asp?issn=0378-6323;year=2003;volume=69;issue=6;spage=423;epage=424;aulast=Amladi
(861 words)
|
|
| |
| | Bioline International Official Site (site up-dated regularly) |
| | Genodermatoses, genetic syndromes, inherited skin diseases and also inflammatory or immunological disorders with a genetic basis occupy an important part of the dermatology curriculum. | | | Immunological or inflammatory disorders with a polygenic inheritance such as atopic dermatitis, psoriasis, alopecia areata and lichen sclerosus are also included. | | | The skin is one of the commonest organ systems involved in genetic or inherited diseases. |
|
http://www.bioline.org.br/request?dv03083
(861 words)
|
|
| |
| | Alibris: W.J. Herbert |
| | The rapid progress in clinical and experimental immunological research, in addition to the radical change in immunological concepts in recent years, has been accompanied by similar developments in the technical vocabulary, and, as a consequence, frequent widespread confusion. | | | This biography illuminates the tragedy of a statesman who believed that pure moral commandments could be applied to human affairs and that in the conflicts of this world a clear choice could be made between good and evil. | | | The fourth edition of The Dictionary of Immunology will satisfy the needs... |
|
http://www.alibris.com/search/books/author/Herbert,W.J.
(861 words)
|
|
|
