Immunogen - Medicow
About us  |  Why use us?  |  Press  |  Contact us

 

Topic: Immunogen



  
 EID Vol 2 No 4:
Immunogenicity of heptavalent pneumococcal conjugate vaccine in infants.
The reason for the vaccine's poor immunogenicity and its lack of efficacy in children is thought to be the nature of the PS antigen.
Safety and immunogenicity of a pentavalent pneumococcal conjugate vaccine in healthy toddlers.
http://www.cdc.gov/ncidod/EID/vol2no4/kayhty.htm

  
 Haemophilus b Conjugate Vaccines for Prevention of Haemophilus influenzae Type b Disease Among Infants and Children Two ...
Immunogenicity studies of each of the three conjugate vaccines have been performed among 2- to 6-month-old children.
However, situations will arise in which the vaccine provider does not know which type of Hib conjugate vaccine the child to be vaccinated had previously received.
Recent studies among Alaskan Native infants and infants in California, however, suggest that the three conjugate vaccines induce markedly different immunologic responses (5,6) ( Table_2).
http://www.cdc.gov/mmwr/preview/mmwrhtml/00041736.htm

  
 Enhanced In Vitro Potency and In Vivo Immunogenicity of a CTL Epitope from Hepatitis C Virus Core Protein following ...
Nevertheless, empirical characterization of in vivo immunogenicity of the peptides to be used as immunogens is important,
A first approach to enhance peptide immunogenicity is to improve the affinity of CTL epitopes for HLA class I molecules ( 34,
humans) were analyzed to define peptides with enhanced immunogenicity.
http://www.jci.org/cgi/content/full/102/6/1239

  
 Pneumococcal Vaccination and Revaccination of Older Adults -- Artz et al. 16 (2): 308 -- Clinical Microbiology Reviews
Studies of immunogenicity have primarily focused on quantitative
clinical data are needed to correlate with the immunogenicity
an immunogenicity study by Carson and colleagues, 29 male and
http://cmr.asm.org/cgi/content/full/16/2/308

  
 Fusion to C3d Enhances the Immunogenicity of the E2 Glycoprotein of Type 2 Bovine Viral Diarrhea Virus -- Wang et al. ...
The immunogenicity of the E2s-C3d construct was assessed by
In this investigation, we studied the effect of fusing C3d to
is under way to devise methods of enhancing the immunogenicity
http://jvi.asm.org/cgi/content/full/78/4/1616

  
 IMMUNOGENICITY OF FDA DTP VERSUS WHO DTP
There is a need for methods of potency assay to be re-evaluated.
The authors acknowledge with thanks the effort of the physicians working in the health centers included in the study, particularly Dr. H.A. Al-Sawi.
A study which was done in Australia showed that the increase in diphtheria or tetanus concentration was not associated with an increase in the reported systemic or local clinical signs associated with the first three doses.
http://www.kfshrc.edu.sa/annals/195/98-271.html

  
 immunogenicity
Immunogenicity of Recombinant Biological Therapeutics: A Practical Approach October 18-19, 2004 San Francisco, CA November 8-9, 2004 Boston, MA Instructors...
immunogenicity The ability to elicit an immune response.
The Phase IIb immunogenicity study will include a total of 200 patients in approximately 10 of the leading cardiothoracic centers in the United States.
http://www.biometnews.com/biotechnology/immunogenicity.html

  
 Enhanced Immunogenicity of CD4+ T-Cell Responses and Protective Efficacy of a DNA-Modified Vaccinia Virus Ankara ...
analysis of the mechanisms of the enhanced immunogenicity of this
There were no significant differences between the DM-MD-DDDM group and the BCG group in any organ in either experiment at
both antigens and assessed the immunogenicity of these constructs,
http://iai.asm.org/cgi/content/full/69/2/681

  
 Science's AIDScience Archive
A Phase I Safety and Immunogenicity Study of HIV p17/p24:Ty-VLP in HIV-1 Seronegative Subjects
A Phase I Safety and Immunogenicity Study Trial of UBI Microparticulate Monovalent HIV-1 MN Peptide Immunogen in HIV-1 Seronegative Human Subjects
A Phase I Safety and Immunogenicity Trial of UBI HIV Lipopeptide Immunotherapeutic in HIV-1 Seronegative Human Subjects
http://aidscience.org/allvaccines.asp

  
 An Endoplasmic Reticulum-Targeting Signal Sequence Enhances the Immunogenicity of an Immunorecessive Simian Virus ...
were immunogenic, the responses induced were weaker, and reliable
were examined as an alternate means of determining the immunogenicity
pathway by ER targeting dramatically enhanced the immunogenicity
http://jvi.asm.org/cgi/content/full/72/2/1469

  
 Comparison of Immunogenicity and Safety of a Virosome Influenza Vaccine with Those of a Subunit Influenza Vaccine in ...
The primary objective of this study was to investigate the immunogenicity and safety of a virosome influenza vaccine (Inflexal
criteria needed to prove immunogenicity regarding each influenza
Immunogenicity of trivalent subunit versus virosome-formulated influenza vaccines in geriatric patients.
http://aac.asm.org/cgi/content/full/44/5/1163

  
 Antitope Ltd - Evaluating Immunity
These results corresponded with the frequency of immunogenicity observed clinically with the various preparations.
Our primary focus is to apply and improve upon existing technologies that model human immune responses to protein antigens.
At Antitope, we pride ourselves on providing tailored projects to meet our clients' needs.
http://www.antitope.com

  
 Gerd Ritter
Many factors will influence the immunogenicity of a therapeutic antibody.
The BIACORE method used in this study fulfills these criteria and is now being utilized in all our studies with humanized antibodies.
To date, only limited information is available on the immunogenicity of humanized therapeutic antibodies in cancer patients.
http://www.cancerresearch.org/antibodies2002/gerd_ritter.html

  
 Development of a novel, nonimmunogenic, soluble human TNF receptor type I (sTNFR-I) construct in the baboon -- ...
The initial baboon study was aimed at determining the immunogenicity and pharmacokinetics of the six different sTNFR-I constructs
Cloning of the baboon TNFR-I. To help interpret the immunogenicity data from systemic administration of various human sTNFR-I constructs into baboons, we
the immunogenicity of the constructs, as the immunogenicity between
http://jap.physiology.org/cgi/content/full/91/5/2213

  
 IIR's third annual immunogenicity for protein-based therapeutics conference
IIR's third annual immunogenicity for protein-based therapeutics conference
http://www.iir-conferences.com/site/_dyn.cfm?iv=12&DirName=CQ4005&ConfCode=CQ4005&day=1&gday=40

  
 Enhanced immunogenicity of HIV-1 vaccine construct by modification of the native peptide sequence -- Ahlers et al. 94 ...
found to be immunogenic in humans, based on preliminary results
Molecular Immunogenetics and Vaccine Research Section, Metabolism Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892
Enhanced immunogenicity of HIV-1 vaccine construct by modification of the native peptide sequence -- Ahlers et al.
http://www.pnas.org/cgi/content/full/94/20/10856

  
 Virtual Naval Hospital: Guide to Clinical Preventive Services, Second Edition
A comparative trial of the reactogenicity and immunogenicity of Takeda acellular pertussis vaccine combined with tetanus and diphtheria toxoids: outcome in 3- to 8-month-old infants, 9- to 23-month-old infants and children, and 24- to 30-month-old children.
Efficacy and immunogenicity of acellular pertussis vaccine by manufacturer and patient age.
A 9-year follow-up study of the immunogenicity and long-term efficacy of plasma-derived hepatitis B vaccine in high-risk Chinese neonates.
http://www.vnh.org/GCPS2/75.html

  
 Elimination of the Immunogenicity of Therapeutic Antibodies -- Gilliland et al. 162 (6): 3663 -- The Journal of ...
The immunogenicity of therapeutic Abs limits their long-term
We based our approach on high zone tolerance
Elimination of the Immunogenicity of Therapeutic Antibodies -- Gilliland et al.
http://www.jimmunol.org/cgi/content/full/162/6/3663

  
 University of Maryland School of Medicine - Center for Vaccine Development
Construction, genotypic and phenotypic characterization, and immunogenicity of attenuated guaBA Salmonella enterica serovar Typhi strain CVD 915.
A murine model of intranasal immunization to assess the immunogenicity of attenuated Salmonella typhi live vector vaccines in stimulating serum antibody responses to expressed foreign antigens.
Determinants of the immunogenicity of live virulent and mutant Vibrio cholerae 01 in rabbit intestine.
http://medschool.umaryland.edu/cvd/publications.asp

  
 Biotechnology :: Biopharmaceutical immunogenicity: association between epoetin alfa and pure red :: Pharmaceutical ...
It is likely that this re-formulation resulted in a subtle change in the immunogenicity of epoetin alfa.
This PRCA is associated with a breakdown of immune tolerance to the epoetin protein with resultant neutralising antibody formation.
Biopharmaceutical immunogenicity: association between epoetin alfa and pure red cell aplasia This short review discusses the possible reasons for the recent upsurge in cases of pure red cell aplasia in chronic kidney disease patients treated with epoetin alfa.
http://www.pharmainfo.net/displayarticle5415.html

  
 Jornal de Pediatria - Immunogenicity of hepatitis B vaccination in preterm infants started soon after birth: ...
While vaccination of premature babies can be delayed, it can become necessary to vaccinate as early as the first 12 hours postpartum if the child's mother is known to be positive for HBsAg or if her infectious status is unknown.
Immunogenicity of hepatitis B vaccine in preterm and full term infants vaccinated within the first week of life.
Nevertheless, research into the immunogenicity of early vaccination (begun during the first few days of life) of preterm NB has been inconclusive with disagreement between the various studies available in published literature.
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0021-75572004000200003&lng=en&nrm=iso&tlng=en

  
 Cytokine-Induced Tumor Immunogenicity: From Exogenous Molecules to Gene Therapy And Arrival Of Autumn In Constantinople
This remarkable book focuses on the field of cytokines and tumor immunogenicity, in which there has been a recent resurgence of interest, especially with the advent of gene therapy.
Cytokine-Induced Tumor Immunogenicity: From Exogenous Molecules to Gene Therapy
http://www.sonnymovie.com/induced.htm

  
 Immunology, Biology 328
However, certain conditions must be satisfied in order for a molecule to be immunogenic.
Immunogens For the induction of humoral immunity (antibody response), the most potent immunogens are macromolecular proteins or glycoproteins, but polysaccharides, synthetic peptides, and other synthetic polymers such as polyvinylpyrrolidone are immunogenic under appropriate conditions.
Too little may not stimulate a strong response, too much may stimulate tolerance.
http://bioweb.wku.edu/faculty/Davis/Biol328/Lecture5.html

  
 Safety and Immunogenicity of a Heptavalent Pneumococcal Conjugate Vaccine in Infants With Human Immunodeficiency Virus ...
Safety and Immunogenicity of a Heptavalent Pneumococcal Conjugate Vaccine in Infants With Human Immunodeficiency Virus Type 1 Infection -- Nachman et al.
Safety and immunogenicity of heptavalent pneumococcal CRM197 conjugate vaccine in i nfants and toddlers.
Immunogenicity was investigated further with the use of serotype-specific
http://pediatrics.aappublications.org/cgi/content/full/112/1/66

  
 Peptides, NIAID Division of AIDS, HIV Vaccine Site
In no case, however, the boost effect of the peptide resulted in broadening of the neutralization response to make it effective against primary isolates.
Controlled-released microparticles and iscom matrix technologies have also been applied to peptide vaccines, however, no extended immunogenicity evaluations of the latter approaches have been conducted.
Limited studies in humans (including HIV seropositive volunteers) have confirmed such immunogenicity: antibody responses, proliferative and CTL responses were generated after 3 doses of the vaccine; adoptive transfer of cells from vaccinees have been shown to protect SCID mice from challenge with HIV-1.
http://www.niaid.nih.gov/daids/vaccine/peptides.htm

  
 BioMed Central Full text Enhanced immunogenicity of a functional enzyme by T cell epitope modification
The ability to induce improved immune responses by the subtle changes described here could have a number of potentially vital applications.
This difference in immunogenicity has been noted by others using an intratracheal method of immunization [ 28, 29 ].
This variant was constructed, and was found to be a functional and stable protease.
http://www.biomedcentral.com/1471-2172/3/2

  
 Biotechnology :: A Risk-Based Approach to Immunogenicity Concerns of Therapeutic Protein Products :: Pharmaceutical ...
This brief review will focus o­n the scientific basis of the Agency's risk assessment strategy for immunogenicity.
A Risk-Based Approach to Immunogenicity Concerns of Therapeutic Protein Products
Yet, for many therapeutic protein products the antibody response has little apparent effect.
http://www.pharmainfo.net/displayarticle9221.html

  
 Safety and immunogenicity of a paediatric presentation of an influenza vaccine -- Gonzalez et al. 83 (6): 488 -- ...
Our results are in contrast to those reported by Groothuis et al, who studied the immunogenicity and safety of a split influenza
Safety and immunogenicity of a paediatric presentation of an influenza vaccine
Bydak LB, Rokicka-Milewska R, Machaa M, Jackowska T, Sikorska-Fic B. Immunogenicity of subunit trivalent influenza vaccine in children with acute lymphoblastic leukemia.
http://adc.bmjjournals.com/cgi/content/full/archdischild%3b83/6/488

  
 Pharmacokinetics, immunogenicity, and efficacy of dimeric TNFR binding proteins in healthy and bacteremic baboon -- ...
Nevertheless, the studies suggest that such dimeric, pegylated TNF-receptor constructs can be generated that are effective
immunogenicity of the different constructs in the healthy baboon.
immunogenic responses to administered human proteins may develop
http://www.jap.org/cgi/content/full/84/4/1119

  
 Immunogenicity in Mamu-A*01 rhesus macaques of a CCR5-tropic human immunodeficiency virus type 1 envelope from the ...
immunogenicity of our vaccine construct with one of the few
In the present study, the immunogenicities of synthetic HIV-1
Immunological and virological analyses of persons infected by human immunodeficiency virus type 1 while participating in trials of recombinant gp120 subunit vaccines.
http://vir.sgmjournals.org/cgi/content/full/84/1/203

  
 Mucosal Adjuvanticity and Immunogenicity of LTR72, a Novel Mutant of Escherichia coli Heat-labile Enterotoxin with ...
The unique property of LT to act as a potent mucosal adjuvant and immunogen has stimulated many studies aimed at understanding
Mucosal immunogenicity of genetically detoxified derivatives of heat labile toxin from Escherichia coli.
B cell epitopes, which may turn out to be those relevant for the
http://www.jem.org/cgi/content/full/187/7/1123

  
 Increased Immunogenicity and Induction of Class Switching by Conjugation of Complement C3d to Pneumococcal Serotype 14 ...
The results presented here suggest that synthetic conjugates of PPS14 and C3d are far more effective immunogens than unmodified
Conjugation of C3d to an immunogen could potentially influence every step of the humoral immune response subsequent to antigen
Error bars represent the 95% CI of the geometric mean for each group of sera.
http://iai.asm.org/cgi/content/full/69/5/3031

  
 HepNet - Dr. Howard Worman - Safety and immunogenicity of hepatitis A vaccine in patients with chronic liver disease.
Safety and immunogenicity of hepatitis A vaccine in patients with chronic liver disease.
HepNet - Dr. Howard Worman - Safety and immunogenicity of hepatitis A vaccine in patients with chronic liver disease.
This multicenter study compared the safety and immunogenicity of inactivated hepatitis A vaccine in patients with chronic liver disease and healthy subjects.
http://www.hepnet.com/hepa/wormanA498.html

  
 : The AMEDEO Literature Guide
Immunogenicity of the seven valent pneumococcal conjugate vaccine in patients with ataxia-telangiectasia.
Immunogenicity of Inactivated Hepatitis A Vaccine in Children With Chronic Liver Disease.
Safety and immunogenicity of a three dose regimen of two tetravalent live-attenuated dengue vaccines in five- to twelve-year-old Thai children.
http://www.amedeo.com/medicine/vac/pedinf.htm

  
 Prevention Guidelines
Hib vaccine is immunogenic in patients with increased risk for invasive disease, such as those with sickle-cell disease (46), leukemia (47), human immunodeficiency virus (HIV) infection (48,49), and in those who have had splenectomies (50).
However, in persons with HIV infection, immunogenicity varies with stage of infection and degree of immunocompromise.
These children should be considered unimmunized, and vaccination should start as soon as possible during the convalescent phase of the illness.
http://www.phppo.cdc.gov/cdcRecommends/showarticle.asp?a_artid=P0000326&TopNum=100&CallPg=Adv

  
 News - StaphVAX Immunogenicity Study in Cardiac Patients Meets Primary Endpoints of Safety and Immune Response
The phase 2b immunogenicity study included a total of 120 patients from 15 cardiovascular surgery centers in the United States.
StaphVAX Immunogenicity Study in Cardiac Patients Meets Primary Endpoints of Safety and Immune Response
News - StaphVAX Immunogenicity Study in Cardiac Patients Meets Primary Endpoints of Safety and Immune Response
http://www.docguide.com/news/content.nsf/news/8525697700573E188525703C006203A0

  
 Immunogenicity of Human Amniotic Membrane in Experimental Xenotransplantation -- Kubo et al. 42 (7): 1539 -- ...
Immunogenicity of Human Amniotic Membrane in Experimental Xenotransplantation
In this study our first approach was to examine the immunogenicity
This study was designed to examine the immunogenicity
http://www.iovs.org/cgi/content/full/42/7/1539

  
 Safety and Immunogenicity of Improved Shigella O-Specific Polysaccharide-Protein Conjugate Vaccines in Adults in Israel ...
The immunogenicity of polysaccharide conjugates in mice or in human adults may not always predict their activity in infants
Further studies on immunogenicity of Haemophilus influenzae type b and pneumococcal 6A polysaccharide-protein conjugates.
Schneerson, and the Israel Pediatric Shigella Study Group.
http://iai.asm.org/cgi/content/full/69/3/1351

  
 : The AMEDEO Literature Guide
Combining anthrax vaccine and therapy: a dominant-negative inhibitor of anthrax toxin is also a potent and safe immunogen for vaccines.
Safety and Enhanced Immunogenicity of a Hepatitis B Core Particle Plasmodium falciparum Malaria Vaccine Formulated in Adjuvant Montanide ISA 720 in a Phase I Trial.
Therapeutic Vaccination against Helicobacter pylori in the Beagle Dog Experimental Model: Safety, Immunogenicity, and Efficacy.
http://www.amedeo.com/medicine/vac/infimm.htm

  
 IMMUNOGENICITY AND SAFETY OF A VARICELLA VACCINE (OKAVAXTM) AND A TRIVALENT MEASLES, MUMPS, AND RUBELLA VACCINE ...
The aim of this study was to assess the immunogenicity and safety
The different numbers of subjects in the immunogenicity analyses
are administered in this way their efficacy or immunogenicity
http://www.ajtmh.org/cgi/content/full/70/3/273

  
 XOMA Licensing Opportunities - Human Engineering™
In Phase I clinical trials, XOMA demonstrated that Human Engineered™ ING-1 had no detectable immunogenicity in the vast majority of patients as detected by a sensitive assay.
The incidence of an immune response to ING-1 was both low and similar to that reported for other humanized antibodies.
The technology uses a unique algorithm developed at XOMA, based on analysis of the conserved structure-function relationships among antibodies.
http://www.xoma.com/licensing_opportunities/human_engr.jsp

  
 Safety and Immunogenicity of a Candidate HIV-1 Vaccine in Healthy Adults: Recombinant Glycoprotein (rgp) 120: A ...
not as immunogenic as that in previous animal studies [21].
Safety and immunogenicity of a human immunodeficiency virus type 1 (HIV-1) recombinant gp160 candidate vaccine in humans.
be an important determinant of the immunogenicity of these glycoproteins.
http://www.annals.org/cgi/content/full/125/4/270

  
 From Proteins and Protein Models to Their Use in Immunology and Immunotherapy -- Sela 278 (49): 48507 -- Journal of ...
and immunogenicity and distinguished it from antigenic specificity.
immunogens leading to antibodies of essentially any specificity.
I was delighted to describe the results on the increase in immunogenicity
http://www.jbc.org/cgi/content/full/278/49/48507?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=&searchid=1090293661568_13280&stored_search=&FIRSTINDEX=0&tocsectionid=Reflections

  
 Specific Targeting, Biodistribution, and Lack of Immunogenicity of Chimeric Anti-GD3 Monoclonal Antibody KM871 in ...
Pegram MD, Lipton A, Hayes DF, et al: Phase II study of receptor-enhanced chemosensitivity using recombinant humanized anti-p185HER2/neu monoclonal antibody plus cisplatin in patients with HER2/neu-overexpressing metastatic breast cancer refractory to chemotherapy treatment.
This lack of immunogenicity is of importance in
Specific Targeting, Biodistribution, and Lack of Immunogenicity of Chimeric Anti-GD3 Monoclonal Antibody KM871 in Patients With Metastatic Melanoma: Results of a Phase I Trial
http://www.jco.org/cgi/content/full/19/19/3976

  
 [No title]
Immunogenicity of expressed Hsp60 protein was evaluated with animal experiments.
RESULTS: DNA sequence analysis showed Hsp60 DNA was the same as GenBank¡¯s research.
AIM: To express Hsp60 protein of H pylori by a constructed vector and to evaluate its immunogenicity.
http://www.wjgnet.com/1007-9327/9/2711.asp

  
 Full Text: Immunogenicity of Hylan G-F 20 in Guinea Pigs and Mice
Recent reported severe acute inflammatory reactions in human patients after repeated intraarticular injections of hylan G-F 20 might involve product-specific, immune-mediated mechanisms.
To determine the product-specific immunogenicity of a chemically-modified sodium hyaluronate derivative, hylan G-F 20, that is used in the treatment of osteoarthritis of the knee.
The sera of hylan-immunized guinea pigs showed positive reaction in the homologous PCA assay and significantly high amount of anti-hylan IgG, whereas the sera did not show any cross-reactivity against sodium hyaluronate.
http://www.jrheum.com/abstracts/abstracts04/943.html

  
 Field evaluation of the efficacy and immunogenicity of recombinant hepat
sandorandfay@extra.co.nz [Medline record in process] A study involving more than 2,000 infants was conducted in Vietnam to assess the field effectiveness and immunogenicity of recombinant hepatitis B vaccine given at birth, 1 month, 2 months, without concomitant hepatitis B immune globulin (HBIG).
Next by Date: Preponderance of hepatitis B virus genotype B contributes to a better prognosis of chronic HBV infection in Okinawa, Japan
Field evaluation of the efficacy and immunogenicity of recombinant hepatitis B vaccine without HBIG in newborn Vietnamese infants
http://archive.mail-list.com/hbv_research/msg03750.html

  
 Immunogenicity Testing
We will serve you by providing assurance of the level of immunogenicity of your product.In early clinical testing we can provide a sensitive, specific assay to evaluate your trial patients independently and confidentially.
Knowing the importance of establishing a standardized assay during development, we have experience in developing assays and writing GMP/GLP procedures acceptable to regulatory agencies.
Our certification by BSI as ISO13485 compliant assures you of this level of quality.
http://www.antibodiesinc.com/CatalogProducts.asp?nProductsID=166

  
 Exogenous stress proteins enhance the immunogenicity of apoptotic tumor cells and stimulate antitumor immunity -- Feng ...
provide adjuvant effects that may enhance the immunogenicity of
Tumor immunogenicity is determined by the mechanism of cell death via induction of heat shock protein expression.
Exogenous stress proteins enhance the immunogenicity of apoptotic tumor cells and stimulate antitumor immunity -- Feng et al.
http://www.bloodjournal.org/cgi/content/full/101/1/245

  
 Immunogenicity - Science & Technology - Trubion Pharmaceuticals Inc.
Novel proteins can be particularly immunogenic but even fully human antibodies can lead to such reactions.
SMIPs have not proven to be significantly immunogenic in animal studies including non-human primates.
Immunogenicity - Science and Technology - Trubion Pharmaceuticals Inc.
http://www.trubion.com/sci_tech_immunogenicity.asp

 About us   |  Why use us?   |  Press   |  Contact us

 Copyright © 2006 Medicow.com Usage implies agreement with terms.