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Topic: Immune cell


  
 MedlinePlus Medical Encyclopedia: Immune response
Usually, the action of the immune response is desired.
Vaccination (immunization) is a way to trigger the immune response.
Acquired immunity is when the body is exposed to various antigens and builds a defense that is specific to that antigen.
http://www.nlm.nih.gov/medlineplus/ency/article/000821.htm   (1151 words)

  
 Immune System
Parts of the immune system are antigen-specific (they recognize and act against particular antigens), systemic (not confined to the initial infection site, but work throughout the body), and have memory (recognize and mount an even stronger attack to the same antigen the next time).
The human immune system is a truly amazing constellation of responses to attacks from outside the body.
Parts of the immune system are changeable and can adapt to better attack the invading antigen.
http://uhaweb.hartford.edu/BUGL/immune.htm   (3339 words)

  
 CBC News:Experimental therapy uses immune cells to beat cancer
Eliminating the patient's own immune system and improving the way anti-cancer cells are grown in the lab improved the technique's success rate.
The treatment still has a lot of rough edges and is years away from being used on other cancer patients, but the study shows boosting our immune systems may be a way to successfully fight off invading cancers.
"What we've done is figure out a way to greatly increase the number of immune cells in the body that can attack the cancer," said Dr. Steven Rosenberg of the National Cancer Institute in Bethesda, Md., who led the study.
http://www.cbc.ca/stories/print/2002/09/19/cancer_tcells020919   (518 words)

  
 Cancer disarms immune stystem cells
Whether the immune system even responds to cancer has been unclear and somewhat controversial, said Peter P. Lee, MD, a postdoctoral fellow in hematology and immunology and lead author of a paper published in the June issue of Nature Medicine.
The first step was to analyze blood samples from 11 patients with metastatic melanoma, in which the cancer had spread from its origin in the skin.
Using a speedy new method for analyzing immune system activity, a Stanford-led research team has discovered how the cancer manages to evade the normally watchful immune system.
http://mednews.stanford.edu/releases/1999/junreleases/immune.html   (836 words)

  
 Information on the immune system - InnerVibrance.Com
Proper digestion is key to a healthy immune system, by exercising you are also promoting better digestive function which will aid in keeping your body clean of toxins and keep the immune system healthy.
To be effective, the immune system must have the ability to recognize these clever, camouflaged intruders and destroy them before they do any damage to the body.
This immune response is generally the same towards all invaders.
http://www.innervibrance.com/immune_system   (828 words)

  
 HRF Greenpapers: Boosting Immunity
This safe and effective immune stimulant was discovered and first used by the Native Americans and is now a major medicinal plant used throughout Europe and the U.S. The Herb Research Foundation (HRF) is dedicated to returning safe natural remedies to prominence in modern health care.
The study concluded, "a complete immune restoration can be achieved by using a fractionated extract of Astragalus membranaceus, a traditional Chinese medicinal herb found to possess immune restorative activity in vitro".
We conduct, support and encourage research and educational projects in the areas of health, conservation and international development.
http://www.herbs.org/greenpapers/immune.html   (1989 words)

  
 GMHC: Immune Basics
It is often these germs and bugs - some of which may have been inside your body and controlled by your immune system since childhood — that make you sick in the course of HIV illness.
Deciding whether to treat HIV or not is a tough decision.
Getting sick is often a sign that your body is responding to invaders from the outside.
http://gmhc.org/health/treatment/immune_basics.html   (844 words)

  
 Science News Online (6/13/98): Immune Attack on Cancer Researchers spur the immune system to rout malignancies
A U.S. team used the same immune therapy to treat prostate cancer, the second leading cause of death in men in the United States.
Researchers have seen a handful of dramatic responses to immune therapy, but so far, such responses have been limited to melanoma.
All had been treated with a variety of standard therapies, including chemotherapy, radiation therapy, and surgery, but their cancer continued to spread aggressively.
http://www.sciencenews.org/sn_arc98/6_13_98/bob1.htm   (1886 words)

  
 BBC NEWS Health Immune cells 'beat cancer'
US researchers used the cells to treat patients with skin cancer who had not responded to other therapies, and saw "promising" results.
They hope more research will allow the technique to be used to treat different types of cancer and infectious diseases such as Aids.
I think that really is a step forward."
http://news.bbc.co.uk/1/hi/health/2268735.stm   (617 words)

  
 Immune System - Vitacost
This may be beneficial in patients with cancer, AIDS, and other immune system deficiencies, although the published studies are limited.
Ashwagandha works to stimulate the immune system overall, with many components that promote general wellness.
Scientists have come to realize that stress and improper nutrition can lead to a breakdown in the immune system.
http://www.vitacost.com/ImmuneSystem.html   (1442 words)

  
 Immune System - NIAID Net News
The organs of the immune system, positioned throughout the body, are called lymphoid organs.
Pockets of lymphoid tissue are in many other locations throughout the body, such as the bone marrow and thymus.
The immune system is a complex of organs--highly specialized cells and even a circulatory system separate from blood vessels--all of which work together to clear infection from the body.
http://www.niaid.nih.gov/final/immun/immun.htm   (979 words)

  
 Science News: Hormone wards off immune cells in womb - Science News of the week - corticotropin-releasing hormone - ...
The possibility of manipulating a woman's immune response with antalarmin could lead to new methods for ending early pregnancies, says Makrigiannakis' team.
Fewer embryos attached successfully to the uterus in rats receiving antalarmin than in control rats.
This suggests that the CRH-FasL relationship plays its anti-immune role only in very early pregnancy, say the researchers.
http://www.findarticles.com/p/articles/mi_m1200/is_16_160/ai_80680524   (694 words)

  
 Cell biology glossary
A better understanding of the pathway cell use to sense and respond to shape changes may lead to new treatments for various diseases.
Laser capture microscopy techniques have increased the ease of isolating specific cells or organelles for subsequent molecular analysis.
This integrated process choreographs the morphogenesis of the embryo during development.
http://www.genomicglossaries.com/content/cell_bio.asp   (6668 words)

  
 September 25, 2003 - Researchers Solve the Mystery of a Key Structure in Immune System Cells
The immune cell structure acts much like the iris in the eye, which adjusts to let vision function from very dark to very bright conditions, explains Michael Dustin, Ph.D., the Irene Diamond Associate Professor of Immunology at NYU School of Medicine, one of the study’s lead authors.
Dustin explains why such a range of sensitivity is necessary for the immune system: "In some cases, you have pathogens that, perhaps because they’re trying to evade the immune response, won’t generate many of these antigenic structures.
Researchers are hopeful that now that the role of this channel of communication has been identified, it may serve as a potential target for treating diseases — those in which the body attacks itself, such as in arthritis, as well as those in which the body doesn’t recognize the attacker, such as tumors.
http://www.med.nyu.edu/communications/news/pr_26.html   (1332 words)

  
 The Immune System
When our immune system is weakened, the invaders soon take over, resulting in disease and/or premature death.
The invisible threats of radiation and harmful electromagnetic waves cause additional problems for our immune systems.
Many believe the ever increasing rates of cancer in the U.S. are the result of an epidemic of chronic malnutrition leading to chronic immune deficiency.
http://immune.altmedangel.com/immune.htm   (1218 words)

  
 Cell Wars
Here on Earth, doctors have learned that stress can suppress the immune system by causing the body to release hormones that affect the way T-cells behave.
Indeed, some are even helpful -- and the ones that aren't are kept in check by our vigorous immune system, which marks and destroys pathogens before they get out of control.
Rather than looking at the human immune system as a whole, Pellis and his colleagues can examine the possible effects of low-gravity on individual immune cells.
http://science.nasa.gov/headlines/y2002/23jan_cellwars.htm   (1381 words)

  
 Molecule That Guides Nerve Cells Also Directs Immune Cells
"This similarity between the immune system and nervous system might suggest new therapeutic approaches to immune system disorders such as inflammation and autoimmune diseases," says Yi Rao, Ph.D., an associate professor of anatomy and neurobiology at Washington University School of Medicine in St. Louis.
New Research Sheds Light On Basics Of How Neurons Communicate (October 7, 2004) -- Nerve cells with a mutant calcium channel don't communicate as effectively as those with a normal calcium channel, according Saint Louis University research that is published in the Proceedings...
This study was a collaboration between the School of Medicine and Baylor College of Medicine.
http://www.sciencedaily.com/releases/2001/04/010419072152.htm   (761 words)

  
 FOCUS - December 13, 2002 - MEDICINE: Immune Cells May See Strain of HIV But Be Blind to Viral Cousin
Researchers have known for some time that HIV comes in a variety of strains, but what has not been clear is how good the human immune system is at recognizing different variants.
Working with HMS instructor in medicine Eric Rosenberg, he hatched a plan: find a newly infected person and treat him immediately with antiretroviral drugs.
While moonlighting in a medical walk-in clinic, Rosenberg found such a person.
http://focus.hms.harvard.edu/2002/Dec13_2002/medicine.html   (1152 words)

  
 HIV's Deadly Assault on Immune Cells Chronicled
This web-based microarray analysis tool was developed by members of the UCSD Center for AIDS Research Genomics core, the San Diego Supercomputer Center, and the UCSD Cancer Center, and is available at http://www.array.ucsd.edu.
The research was supported by the National Institute of Allergy and Infectious Diseases, the Center for AIDS Research Genomics Core laboratory, the Universitywide AIDS Research program, the San Diego Veterans Medical Research Foundation, and the San Diego VA Healthcare System.
Jacques Corbeil, Ph.D. "Better understanding of the steps involved in HIV destruction of immune system cells opens the door to new investigations of methods to potentially block or prevent HIV infection," said Jacques Corbeil, Ph.D., assistant professor of medicine at the University of California, San Diego (UCSD) School of Medicine and the paper's first author.
http://health.ucsd.edu/news/2001/06_07_Corbeil.html   (826 words)

  
 Putting Genes In Stem Cells To Activate Immune System
The researchers will conduct further studies to explore the possibility of delivering genes that boost the immune system to develop stronger therapeutic cancer vaccines.
APCs play a central role in controlling immune system responses.
The researchers also will study using this technique to overcome immune system-mediated rejection of embryonic stem cell transplants.
http://unisci.com/stories/20021/0110024.htm   (462 words)

  
 Americans for Medical Progress : Tumor-targeted immune cells cure prostate cancer in mice
Chung Lee, John T. Grayhack, M.D., Professor of Urology at Northwestern University Feinberg School of Medicine, and his laboratory group described the adoptive transfer gene therapy technique in the March issue of Cancer Research.
Biomarker test may give early warning of brain woes
Immune therapy could treat leukemias, autoimmune diseases, transplant rejection
http://www.ampef.org/News/News.cfm?ID=792&c=62   (374 words)

  
 HHMI News: HIV Hijacks Immune Cells to Enter the Body
Researchers have discovered how the human immunodeficiency virus (HIV) first enters the body through mucosal surfaces such as the rectum, cervix and uterus.
But we lacked a broader understanding of what actually happens in the body during infection, and that ignorance has contributed to our difficulties in developing therapies and vaccines.”
Dendritic cells are normally the watchdogs of the immune system, patrolling skin and mucosal surfaces.
http://www.hhmi.org/news/littman3.html   (889 words)

  
 Henry Ford Health System
The most important ones keep the body from rejecting the new organ.
Researchers continue to work on more effective drugs to prevent rejection.
These immune cells notice the transplanted organ is different from the rest of the body and start to attack it. To prevent rejection, patients take drugs to slow down the immune system.
http://www.henryfordhospital.com/body.cfm?id=45264&oTopID=45264   (617 words)

  
 White blood cell - Wikipedia, the free encyclopedia
They help to defend the body against infectious disease and foreign materials as part of the immune system.
As well as in the blood, white cells are also found in large numbers in the lymphatic system, the spleen, and in other body tissues.
Histiocytes, found in the lymphatic system and other body tissues, but not normally in blood:
http://en.wikipedia.org/wiki/Immune_cell   (444 words)

  
 Immune System Anatomy
The organs of the immune system are stationed throughout the body.
Nonencapsulated clusters of lymphoid tissue are found in many parts of the body.
Once in the bloodstream, the lymphocytes and other assorted immune cells are transported to tissues throughout the body.
http://www.immunecentral.com/immune-system/iss4.cfm   (702 words)

  
 Medical College of Wisconsin - Immune System Cells Identified as Potential Tool to Improve Transplants
With support from the National Institute of Health's National Heart, Lung and Blood Institute, Dr. Truitt and his team are building on what they've learned in order to develop their method of increasing the number of the needed cells outside the patient's body and then putting them back into patients.
Bone marrow transplant is used to treat cancers of the blood, such as leukemia and lymphoma, as well as congenital immune deficiency diseases and aplastic anemia.
The goal would be to supply patients with functioning cells to correct the defect and turn off the body's immune response to its own tissue.
http://www.mcw.edu/display/router.asp?docid=1921   (1018 words)

  
 Cells Stop Immune Inflammation 071003
From this study, we now have a foundation for developing new therapies to restore immune privilege in this part of the eye, and thereby prevent vision loss from inflammation.”
The discovery, the authors believe, will ultimately lead to therapies for diseases such as uveitis, herpes and viral eye infections that affect millions worldwide and are caused by an unchecked immune response in the eye.
Inflammation, which is the usual way the body defends itself, can also harm irreplaceable normal tissues of the organs it is trying to defend.
http://www.theschepens.org/cells_stop_immune_inflammation_071003.htm   (597 words)

  
 Cancer Issues - Genetic Technique Bolsters Immune Cells to Battle Cancer
This, in part, has made it difficult to use immune system/TAA interactions to develop immunotherapies to treat cancer, the researchers said.
This research provides new understanding about how to prompt the immune system to specifically and efficiently target cancer cells, and may provide the basis for development of new immunotherapy to treat cancer, the researchers said.
Genetic Technique Bolsters Immune Cells to Battle Cancer
http://www.cancerissues.com/ms/news/523579/main.html   (329 words)

  
 'Smart' Immune Cells Kill More Cancer
"It is very difficult to design cancer therapies that get the body's immune system to recognize and kill cancer cells that the system has ignored for a long time," says Ivan Borrello, M.D., assistant professor of oncology and director of the research, which is published in the March 1 issue of Cancer Research.
Trial At Jefferson Shows New Drug May Help Cancer Patients Who Need Stem Cell Transplants (September 8, 2005) -- A new drug may help cancer patients mobilize stem cells necessary to restore their blood-forming system after high-dose chemotherapy, according to clinical trial results.
Kimmel Cancer Center researchers are planning studies in a small number of myeloma patients to test the activated marrow T-cells alone and in combination with a myeloma vaccine.
http://www.sciencedaily.com/releases/2005/03/050309103441.htm   (743 words)

  
 Genetically modified natural killer immune cells attack, kill leukemia cells
This finding, from researchers at St. Jude Children's Research Hospital, suggests a way to improve the outcome of children who receive treatment for acute lymphoblastic leukemia (ALL) or other blood cancers.
A potential clinical application for the technology developed in this study is in leukemia patients who are treated with hematopoietic (blood cell-forming) cell transplantation.
In another application, NK cells could be obtained from a patient while in remission and then reinfused after genetic modification if the patient suffers a resurgence of the leukemia.
http://www.medicalnewstoday.com/medicalnews.php?newsid=21818   (764 words)

  
 May 3, 2004 Study finds HIV protein can drive immune cells away
"One of the big questions in understanding HIV is why we can see immune responses that are effective in the test tube but do not eradicate the virus in the infected patient," says Mark Poznansky, MD, PhD, of the Partners AIDS Research Center (PARC) and the MGH Infectious Disease Unit, the paper's senior author.
Clue to how virus avoids immune system activity may lead to new treatment strategy
Investigating whether HIV infection involves the same kind of cellular repulsion observed in the earlier study - a process the researchers dubbed "fugetaxis" - seemed a logical next step.
http://www.massgeneral.org/news/releases/050304poznansky.html   (746 words)

  
 Powerful Technologies Probe Innate Immunity
These enormous amounts of data are then integrated and examined from multiple perspectives to learn how the system as a whole behaves.
Ulevitch and his co-investigators face a daunting task-identifying the thousands of genetic changes, proteins generated and biochemical pathways triggered by encounters between innate immune system cells and infectious agents.
Scientists at TSRI, ISB and Rockefeller University will focus on human innate immune system genes that are turned either off or on when a cell meets an infectious organism.
http://www2.niaid.nih.gov/Newsroom/Releases/innateimmunity.htm   (765 words)

  
 Fat Cells Boost Immune System
Here's where you can learn more about the health risks of being overweight (www.niddk.nih.gov).
MONDAY, Jan. 26 (HealthDayNews) -- Fat cells usually take the rap for a number of health problems, but a Purdue University study says they may help the body defend itself against such diseases as diabetes and cancer.
"This is additional evidence that fat cells behave in many ways as immune cells.
http://www.healthcentral.com/newsdetail/408/517073.html   (342 words)

  
 NIH News--Donor Immune Cells Attack Metastatic Breast Cancer--06/01/2003
Researchers are optimistic that further study could lead to effective immunotherapies for these patients.
HLA-matched donor cells, which have the same set of proteins (known as human leukocyte-associated antigens) on their surface as the patient's own cells, are much more likely to be accepted by the patient's body.
A minor response was seen in three of the other patients.
http://www.nih.gov/news/pr/jun2003/nci-01.htm   (487 words)

  
 HIV and AIDS Tutorial
The immune system protects the body from invading disease-causing organisms, or pathogens.
Pathogens and other non-self molecules are antigens &; foreign molecules recognized by the immune system, stimulating an immune response.
The significance of the dendritic cells is that they can prevent you from reacting against your own tissues, against food that you ingest or harmless materials from your environment, or they can tell the rest of your immune system to make an adaptive immune response.
http://www.biology.arizona.edu/immunology/tutorials/AIDS/response.html   (701 words)

  
 Cells of the Immune System
Polymorphs and mast cells are also involved in the effector side of the immune response.
These cells are derived from the bone marrow and have a variety of functions in the immune response:
appreciate the common origin of the cells of the immune system from the bone marrow
http://www-micro.msb.le.ac.uk/MBChB/2a.html   (231 words)

  
 CBC News: Stress speeds up aging of immune cells by 10 years
Previous studies have shown a link between chronic stress and heart disease and weaker immune function.
Telomeres are the focus of a new study on stress and aging.
WASHINGTON - Chronic stress seems to trigger the premature aging of immune system cells, a new study suggests.
http://www.cbc.ca/story/science/national/2004/11/30/aging-stress041130.html   (423 words)

  
 Jellyfish protein illuminates active immune cells
Enter Schaefer, who was working in the Marrack and Kappler lab to develop methods of using GFP-tagged proteins to observe molecular movements in immune system cells.
October 22, 1999--Researchers have illuminated a crucial step in the immune system's response to infection by using live cell imaging to follow the movement of immune system cells that have been genetically manipulated to produce a fluorescent jellyfish protein.
Further experiments showed that interfering with MEKK2 blocked subsequent pathways that normally carry molecular signals to the nucleus.
http://www.eurekalert.org/pub_releases/1999-10/HHMI-Jpia-211099.php   (708 words)

  
 General Immunology
This page will introduce host defense mechanisms by defining some commonly used terms and describing the specific cells and tissues involved in these immune responses.
Antigen (Ag): A molecule which elicits a specific immune response when introduced into an animal.
Accessible (the immune system must be able to contact the molecule), and
http://www.cehs.siu.edu/fix/medmicro/genimm.htm   (539 words)

  
 Boston.com / News / Nation / Study says AIDS hits immune cells in days
But SIV is a good model and works in a similar way.
But HIV is different because it targets the immune system, and the two studies show how quickly it makes it impossible for its victims to launch a defense.
Normally during an infection such cells would recognize and latch onto an invader, helping other components of the immune system destroy it.
http://www.boston.com/news/nation/articles/2005/03/28/study_says_aids_hits_immune_cells_in_days   (420 words)

  
 Health Watch -- Immune Cells
A discovery about the way immune cells work could help doctors treat a variety of diseases.
Mark Siegelman, the UT Southwestern scientist who led the study, says these immune cells may be a target for future treatments for diseases like rheumatoid arthritis.
This discovery is important not just for understanding how the body fights infection but also for how autoimmune diseases may work.
http://www.utsouthwestern.edu/utsw/cda/dept16498/files/168929.html   (272 words)

  
 Immune System T Cells Lymphokines
T cells contribute to the immune defenses in two major ways.
A number of cytokines, obtained in quantity through recombinant DNA technology (Genetic Engineering), are now being used-alone, in combination, linked to toxins-in clinical trials for patients with cancers, blood disorders, and immunodeficiency diseases (including AIDS), as well as people receiving bone marrow transplants.
In addition to ridding the body of cells that have been infected by viruses or transformed by cancer, they are responsible for the rejection of tissue and organ grafts.
http://www.immunecentral.com/immune-system/iss8.cfm   (551 words)

  
 Scope
A useful glossary of common allergens/allergies and the immune cells involved in these processes, as well as medical terminology used to describe allergies.
Includes latest news and reviews about research in allergy and infectious disease.
This is the result of a collaborative effort to obtain a molecular definition of the human haematopoietic stem cell.
http://www.nature.com/nri/info/links.html   (1046 words)

  
 NPR : Researchers Examine Immune Cells' Workings
Morning Edition, September 22, 2005 · A team of scientists at the University of Pittsburgh says that immune cells have an unusual way of communicating with each other when the time comes to fight off an invader.
http://www.npr.org/templates/story/story.php?storyId=4858817&ft=1&f=3   (108 words)

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