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| | History - Berger's disease before Berger |
 | | The role of the IgA, or lack of it, in the evolution of the associated nephritis has been the subject of 30 years’ more debate, which continues today. | | | In 1957 Bates, Jennings and Earle as part of a study of acute nephritis, noted immediate post-pharyngitic macroscopic haematuria with proteinuria in 10 young soldiers with normal serum complement concentrations and normal ASOTs. | | | However the few laboratories studying immunofluorescence in biopsies at that time mostly used only anti-IgG reagents, as this was thought to be the predominant immunoglobulin class involved in the immunopathogenesis of nephritis. |
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http://www.igan-world.org/bergercameron.htm
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| | IGAN |
| | The incidence of the IgA nephropathy ranges from 8.4 patients/pmp in Italy to 26 patients/pmp in France (3,4). | | | The discovery of gene(s) responsible for the hereditary transmission of the disease may give more information on the aetiopathogenesis of the disease and may give more specific and effective approaches to therapy. | | | For the first time Egido et al distinguished a familial form, in which more than 2 relatives have biopsy-proven IgA nephropathy, from a sporadic form in which only one family member is affected by the disease (8). |
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http://www.igan.net/iga.html
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| | Specialty Laboratories ::: we help doctors help patients |
| | Evidence that the interaction between circulating IgA and fibronectin is a normal process enhanced in primary IgA nephropathy. | | | Beneficial efffect of fibonectin administration on chronic nephritis in rats. | | | IgA-fibronectin aggregates (IgA-Fn) are associated with IgA nephropathy (IgAN; mesangial IgA glomerulonephritis), the most common form of primary glomerulonephritis worldwide. |
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http://www.specialtylabs.com/books/print_view.asp?id=65
(1155 words)
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| | Building the case for biopsy in IgA nephropathy - College of American Pathologists |
| | Lack of accepted therapy for IgA nephropathy is due in part to faulty clinical trials, says Robert J. Wyatt, MD, professor of pediatrics and preventive medicine at the University of Tennessee Health Science Center and Crippled Children's Foundation Research Center, Memphis. | | | That is one criticism of studies on the efficacy of fish oil in IgA nephropathy conducted by James Donadio, MD, and his colleagues at the Mayo Clinic. | | | Summarizing a clinical conference on IgA nephropathy that he co-chaired at the 2000 annual meeting of the American Society of Nephrology, J. Charles Jennette, MD, says, "The conference emphasized that there are still a lot of unresolved issues in clinical management, etiology and pathogenesis, and pathological evaluation of IgA nephropathy." |
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http://www.cap.org/apps/docs/cap_today/feature_stories/feat2_1101.html
(2642 words)
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| | nephritis |
| | Because the patient experienced hematuria rather than hemoglobinuria, nephritis was suggested. | | | membranoproliferative GN, IgA nephropathy), collagen vascular diseases (systemic lupus erythematosus), systemic vasculitis (Henoch Schonlein purpura) and hereditary nephritis and some nonglomerular conditions. | | | Title Natural history and treatment of lupus nephritis. |
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http://www.ais.up.ac.za/med/nephritis.htm
(7986 words)
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| | IgA Nephropathy |
| | Further studies are needed to determine the long-term effectiveness and safety of this drug for the treatment of IgA Nephropathy. | | | However, if the drug is discontinued, most affected individuals will experience a relapse. | | | There may be associated pain in the loin area. |
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http://hw.healthdialog.com/kbase/nord/nord587.htm
(1136 words)
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| | IgA Nephropathy |
| | Complete IgA nephropathy information from the patient's perspective, with medical... | | | Treatment of IgA Nephropathy in Children An evidence based approach | | | Post a question or comment on our Message Board |
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http://www.health-nexus.com/iga_nephropathy.htm
(286 words)
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| | The Foundation for IgA Nephropathy |
| | We have no doctors or health professionals here, except some who might happen to be members of the email support group because they or a family member has IgA nephropathy. | | | The Foundation for IgA Nephropathy welcomes your feedback, suggestions or general questions about the website or administrative matters. | | | We do have many long-time IgAN patients though - which is what a peer support group is all about. |
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http://www.igan.ca
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| | eMedicine - Henoch-Schönlein Purpura (Anaphylactoid Purpura) : Article by Robert J Willard, MD |
| | One uncontrolled study showed the benefit of combination therapy in severe HSP nephritis with methylprednisolone, cyclophosphamide, and dipyridamole. | | | Some studies also have suggested that corticosteroid therapy may prevent the onset of delayed-HSP nephritis or lessen the severity of glomerular injury. | | | Dapsone, azathioprine, and IV immunoglobulin therapies have been tried with varying success, as has plasmapheresis. |
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http://www.emedicine.com/derm/topic177.htm
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| | What IgAN is (a summary) |
| | People have considered allergies, things they may have been exposed to, foods, occupations, blood types, etc. So far, hundreds if not thousands have not been able to identify any such link. | | | IgAN patients who have a particularly "weakened immune system" may have it for other reasons than the IgAN. | | | It is not an autoimmune disease in the classic sense of that term, but it does involve the immune system. |
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http://www.igan.ca/id45.htm
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| | eMedicine - Henoch-Schoenlein Purpura : Article by Noah S Scheinfeld, MD, JD, FAAD |
| | HSP and IgA nephropathy have occurred in the same families. | | | (6) Similar changes in the IgA system (high IgA, IgA-1C, IgA1-IC, IgA-fibronectin aggregates, aberrantly glycosylated IgA in the circulation) occur in both diseases (Coppo, 1984; Davin, 1987; Jennette, 1991). | | | A study of renal pathology disclosed global sclerosis in 35.5% of IgA nephropathy patients and in 3.1% of HSP patients, mesangial sclerosis in 41.9% of IgA nephropathy patients and 6.3% of HSP patients, but endothelial proliferation in 65.6% of HSP patients and 29% of IgA nephropathy patients. |
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http://www.emedicine.com/PED/topic3020.htm
(5824 words)
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| | Lupus Nephritis -- Recommendations and Resources |
| | These drugs appear to increase the chances of speedy remission, but there is much medical debate about their effectiveness in this situation. | | | Other topics related to Lupus Nephritis: Lupus Pain | | | As far as I know, there are few longitudinal studies that follow-up Lupus patients and their causes of death. |
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http://www.becomingapediatrician.com/health/89/lupus-nephritis.html
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| | The Frequency of IgA Nephropathy at a Single Center in Pakistan |
| | The authors concluded that the apparent increase was predominantly a result of an increase in the absolute number of patients with IgA nephropathy presenting with microscopic hematuria and proteinuria, with little change in the incidence of those with episodic macroscopic hematuria. | | | Yoshioka K, Maki S. Human IgA nephritis: immunohistochemical evidence of a chronic inflammatory proliferative disorder. | | | The age range of the patients with IgA nephropathy was 4 to 80 years with a mean age of 28 years. |
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http://jpma.org.pk/JPMA/7july03/fulltext10.htm
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| | IgA nephritis -- Facts, Info, and Encyclopedia article |
| | There is no clear known explanation for the accumulation of the IgA. | | | IgA is the (Any of a large variety of proteins normally present in the body or produced in response to an antigen which it neutralizes, thus producing an immune response) antibody which accumulates in the kidney and probably plays a central role in the disease. | | | It presents with (The presence of blood in the urine; often a symptom of urinary tract disease) hematuria and generally resolves spontaneously, but a proportion of patients develops (Renal failure that can result from a variety of systemic disorders) chronic renal failure. |
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http://www.absoluteastronomy.com/encyclopedia/i/ig/iga_nephritis1.htm
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| | Nephritis |
| | Anyone who has a family history of drug allergies should be on the lookout for nephritis symptoms. | | | Urine and blood analysis is used to detect and diagnose the condition. | | | Genetic disorders, toxic drug reactions and some disorders (including lupus) also cause nephritis. |
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http://www.herbalremedies.com/herbal-remedies-usa/nephritis.html
(1360 words)
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| | MRB: Hypertension and nephritis |
| | eMedicine - Nephritis : Article by Richard Neiberger, MD, PhD - Nephritis - Nephritis is an older term used to clinically denote a child with hypertension, decreased renal function, hematuria, and edema. | | | Chronic Liver Disease and Cirrhosis 15 9 Alzheimer's Disease Septicemia Hypertension Nephritis Nephritis 16 10 Septicemia Hypertension Septicemia Septicemia Septicemia 17 NUMBER OF DEATHS FROM ALL CAUSES... | | | Acute Interstitial Nephritis (AIN) - nephrologychannel - Acute interstitial nephritis (AIN) is rapidly developing inflammation that occurs within the... |
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http://www.medical-research-books.com/mrb-books-reviewed/B00085G97U.html
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| | Untitled Document |
| | Natural history and risk factors for immunoglobulin A nephropathy in Japan. | | | Renal disease in adult Indians : A clinicopathological study of 2827 patients. | | | A retrospective analysis of the natural history of primary IgA nephropathy worldwide. |
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http://www.ijnephrol.com/octdec2003/15.htm
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| | CLINICAL NEPHROLOGY |
| | Angiotensin II Receptor Antagonist (ATRA) Therapy in IgA Nephritis |
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http://www.worldscibooks.com/medsci/5036.html
(220 words)
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| | Renal disease associated with HIV infection: a multicentric study of 60 patients from Paris hospitals. |
| | Interstitial nephritis was present in 48 and 52% of the black and white patients respectively and did not seem related to drug toxicity or superimposed infectious disease. | | | In addition to interstitial nephritis, the coexistence of multivisceral lymphocytic infiltration involving accessory salivary glands, liver and/or lung, found in six patients possibly suggests a virus-induced immune disorder. | | | The frequent hypergammaglobulinaemia in those patients suggests a pathogenic role of polyclonal B cell activation in ICGN. |
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http://www.aegis.com/aidsline/1993/may/M9350131.html
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| | Renal failure |
| | It can be the complication of a large number of kidney diseases, such as IgA nephritis, glomerulonephritis, chronic pyelonephritis and urinary retention. | | | End-stage renal failure (ESRF) is the ultimate consequence, and dialysis is generally required while a donor for renal transplant is found. |
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http://www.therfcc.org/renal-failure-9026.html
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| | IgA Nephropathy |
| | Worldwide idiopathic IgA nephropathy is most common cause of chronic renal failure | | | Renal failure develops in ~30% of patients 5-25 years after diagnosis of idiopathic type | | | Likely has an immune component, antibody associated disease (B cell dysfunction) |
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http://www.outlinemed.com/demo/nephrol/11648.htm
(163 words)
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| | Ny sida 1 |
| | 39) Cederholm, B., Wieslander, J., Bygren, P. and Heinegård, D., Circulating complexes containing IgA and fibronectin in patients with primary IgA nephropathy. | | | 83) Jennette, C., Wieslander, J., Tuttle, R. and Falk, R. Serum IgA-Fibronectin aggregates in patients with IgA nephropathy and Henoch-Schönlein purpura: Diagnostic value and pathogenic implications. | | | 54) Kleppel, M., Kashtan, C., Santi, P., Wieslander, J. and Michael, A. Distribution of the Familial nephritis (FN) antigen in normal tissue and renal basement membranes of patients with homozygous and heterozygous Alport FN. |
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http://www.njur.lu.se/htm/PublistJW.htm
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| | [No title] |
| | Such an association of the gene polymorphism of IL-1ra between HSPN and IgAN with recurrent gross hematuria might serve as a key to explore their pathogenesis and eventually a specific intervention. | | | Journal: Kidney Int Volume: 51 Issue: 6 Pages: 1938-42 Abstract: Henoch-Schonlein purpura nephritis (HSPN) is a multi-organ systemic vasculitis, which shares many clinical, histological and immunological features with IgA nephropathy (IgAN). | | | It was found that the allele frequency and carriage rate of the interleukin-1 receptor antagonist allele (IL1RN*2) of the IL-1ra gene increased significantly in HSPN patients as compared to IgAN (P |
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http://www.bristol.ac.uk/cellmolmed/services/GAI/Datafiles/127.txt
(179 words)
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| | Final Programme WCN 2003, Symposium - Paediatric Clinical Nephrology Conference |
| | IgA1-CONTAINING CIRCULATING IMMUNE COMPLEXES (CIC) FROM IgA NEPHROPATHY (IgAN) PATIENTS DIFFERENTIALLY STIMULATE OR INHIBIT PROLIFERATION OF MESANGIAL CELLS (MC) IN VITRO | | | Second Dept. of Medicine and Nephrological Centre, University of Pecs, Pecs, Hungary | | | IgA nephropathy and Henoch-Schoenlein Purpura nephritis: one single entity or two distinct diseases? |
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http://www.nephrology-2003.org/pedcnc12003.htm
(144 words)
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| | Gluten Enteropathy/Coeliac Support Group |
| | Disorders of the nervous system, such as motor neurone disease, epilepsy, cerebral calcifications, ataxia, tingling and numbness in extremities | | | Autoimmune system disorders: rheumatoid arthritis, insulin dependent diabetes type 1 (mellitus), sarcoidosis, Crohn's disease, multiple sclerosis, myasthenia gravis, muscular dystrophy, pernicious anaemia, scleroderma, Sjögren's syndrome, Addison's disease, autoimmune chronic active hepatitis, systemic lupus erythematosis, thyroid disease, Raynaud's phenomenon, recurrent pericarditis and kidney disease such as IgA nephritis or glomerulonephritis | | | TtG – Tissue transglutaminase AUTO antibody test for gluten |
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http://www.labspec.co.za/coeliac/PAGE2.HTM
(247 words)
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| | Renal and Urologic Disorders, Hematuria Acute Post-streptococcal Glomerulonephritis Hemolytic Uremic Syndrome ... |
| | RBC present on microscopic examination, but No casts: Exercise, fever, sickle hemoglobin, hypercalciuria, stones, familial, coagulopathy, trauma, drugs (eg, Cytoxan), tumors, cysts, hydronephrosis, interstitial nephritis, lower urinary tract infection. | | | Red color is probably caused by dyes or |
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http://www.ccspublishing.com/journals2a/renal_urologic_dis.htm
(219 words)
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| | Renal EQA Circulation X |
| | Diagnostic categories: Score: 1 IgA nephropathy 9.69 2 Henoch Schonlein purpura 0.23 3 FSGS 0.08 Asterisks (if any) indicate dangerous diagnoses. | | | IF negative for IgA, G, M and C3. | | | IgA nephropathy, CUHK-PWH Grade 2, tubulo-interstitial grade 2. |
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http://www.le.ac.uk/iii/pnf1/eqa/X/paeX.html
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