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| | Hydromorphone - Wikipedia, the free encyclopedia |
 | | Hydromorphone is a drug used to relieve moderate to severe pain. | | | When injected, particularily intravenously, hydromorphone produces more intense contraction sensation in the muscles and a more powerful 'rush' than other opioids, even more so than heroin (diacetylmorphine). | | | "Pharmacokinetics and bioavailability of hydromorphone following intravenous and oral administration to human subjects." Journal of Clinical Pharmacology. |
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http://en.wikipedia.org/wiki/Hydromorphone
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| | Hydromorphone (Trade names: Dilaudid, Palladone™) |
| | Hydromorphone is indicated for the relief of moderate to severe pain in patients where an opioid analgesic is appropriate. | | | Pure opioid antagonists such as naloxone or nalmefene are specific antidotes against respiratory depression from hydromorphone overdose. | | | The prescriptions for hydromorphone products have increased by 106 percent, from about 470,000 in 1998 to 970,000 in 2003. |
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http://www.deadiversion.usdoj.gov/drugs_concern/hydromorphone.htm
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| | hydromorphone Drug Information |
| | Hydromorphone is habit forming and should only be used under close supervision by those with an alcohol or drug addiction. | | | An extended-release form of hydromorphone should not be the first narcotic pain medication that has been prescribed to you and should not be used if you will only need pain medicine for a short time or will only be using it occasionally (as needed). |
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http://www.drugs.com/MTM/hydromorphone.html
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| | ACS :: Cancer Drug Guide: hydromorphone |
| | Hydromorphone relieves moderate to severe pain and is similar to morphine. | | | Acetaminophen or aspirin may be combined with hydromorphone to increase the pain relief action. | | | You should be on a bowel regimen to prevent constipation while you are taking opioid pain relievers. |
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http://www.cancer.org/docroot/CDG/content/CDG_hydromorphone.asp
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| | [No title] |
| | The use of opioids for moderate to severe acute pain and in patients with cancer pain now stands as unchallenged standard practice, while the use of opioids for selected patients with chronic non-malignant pain is gaining acceptance. | | | The short elimination half-life of hydromorphone, combined with the rapid absorption phase of the preferred embodiments, permits prompt attainment of steady-state, a stable therapeutic profile, and an early assessment of the patient's pain status. | | | While the early interest in long-term analgesia arose from the worldwide problem of inadequate pain control among cancer patients, many researchers now recognize a substantial population of patients with non-malignant pain who do not receive satisfactory relief. |
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http://www.wipo.int/cgi-pct/guest/getbykey5?KEY=00/18378.010719&ELEMENT_SET=DECL
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| | ASA: Hydromorphone Analgesia Shorter Than That of Morphine but Side Effects Similar |
| | Patient-controlled analgesia (PCA) with hydromorphone was started postoperatively in all patients with the onset of pain. | | | According to Dr. Chiarella, patients who are intolerant to morphine might benefit from taking hydromorphone instead, although the two drugs are structurally related, he pointed out. | | | Duration of effective spinal analgesia was longer with morphine in the hip group: 527 minutes versus 421 minutes (p=0.035) and approached significance in the knee group 453 minutes versus 385 minutes (p=0.059). |
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http://www.docguide.com/dg.nsf/PrintPrint/FA71EFE6BBE78C1385256C550069D743
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| | The Health Report: 28 January 2002 - Hydromorphone Trials |
| | Hydromorphone is an injectable opioid that has similar effects to heroin. | | | I think the conditions under which Hydromorphone would be prescribed in the type of trial we had in mind would be the same as in Switzerland, that is the drug would only be administered on site under medical supervision; there'd be no take-away doses. | | | Australian researchers have proposed to trial hydromorphone for heroin addicts. |
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http://www.abc.net.au/rn/talks/8.30/helthrpt/stories/s469267.htm
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| | Hydromorphone - Patient UK |
| | Hydromorphone is used to treat severe pain and is particularly useful for treating pain associated with cancer. | | | Never give it to others even if their condition appears to be the same as yours. | | | Before taking any 'over-the-counter' medicines, check with your pharmacist which medicines are safe for you to take alongside hydromorphone. |
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http://www.patient.co.uk/showdoc/30003682
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| | Nursing Spectrum- Career Fitness Online |
| | Hydromorphone hydrochloride was approved in late 2004 for moderate to severe chronic pain experienced by opioid-tolerant individuals. | | | Nurses should expect to closely observe patients who are switching from hydromorphone hydrochloride therapy to another pain reliever. | | | Patient teaching should include information on new pain relief medications and a warning not to abruptly discontinue hydromorphone hydrochloride without first consulting the prescribing health care provider. |
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http://nsweb.nursingspectrum.com/NurseNewsEzine/DrugNews/item.cfm?ID=176
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| | Hydromorphone |
| | The feeling of pain and a person's response to pain are also decreased. | | | If you have an allergy to hydromorphone or any other part of the medicine. |
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http://www.umm.edu/altmed/ConsDrugs/Hydromorphonecd.html
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| | ASA: Hydromorphone Better than Fentanyl for Bupivacaine Epidural for Spine Surgery |
| | ORLANDO, FL -- October 16, 2002 -- Epidural hydromorphone 20mg/ml plus bupivacaine 0.01 percent is associated with less postoperative pain and reduced need for rescue analgesics in patients undergoing spine surgery, compared with epidural fentanyl 4mg/ml plus bupivacaine 0.01 percent. | | | "Hydromorphone plus bupivacaine is clearly the preferred analgesic regimen after spine surgery," Dr. Subramaniam concluded. | | | To compare the efficacy of the postoperative analgesics, Dr. Subramaniam randomized 101 patients having lumbar spine surgery into one of two treatment groups: fentanyl 4 µg/mL plus bupivacaine 0.01 percent (n=39), or hydromorphone 20 µg/mL plus bupivacaine -0.01 percent (n=62). |
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http://www.pslgroup.com/dg/2206a2.htm
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| | Effective treatment of elderly patients with severe pain using sustained release hydromorphone |
| | A large-scale, multi-centre trial of 2,650 elderly patients with severe and very severe pain of varying aetiologies was designed to assess the efficacy of treatment with SR hydromorphone. | | | Investigators demonstrated a positive efficacy for the use of sustained-release (SR) hydromorphone in elderly patients with severe pain. | | | The average age of patients enrolled onto the study was between 60-79 years. |
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http://www.medicalnewstoday.com/medicalnews.php?newsid=29573&nfid=rssfeeds
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| | MedlinePlus Drug Information: Hydromorphone Hydrochloride Injection |
| | Your health care provider may tell you to stop your infusion if you have a mechanical problem (such as a blockage in the tubing, needle, or catheter); if you have to stop an infusion, call your health care provider immediately so your therapy can continue. | | | The drug will be either injected into a large muscle (such as your buttock or hip) or added to an intravenous fluid that will drip through a needle or catheter placed in your vein or under your skin. | | | If you are receiving hydromorphone intramuscularly (in your muscle), your health care provider will tell you how to store it properly. |
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http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a601148.html
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| | [No title] |
| | There is no intrinsic limit to the analgesic effect of hydromorphone ; like morphine, even the most severe pain can be relieved given a sufficient amount of hydromorphone. | | | These chromatograms could be re- integrated if necessary. | | | Hydromorphone is also a centrally acting narcotic anti-tussive, which acts directly on the cough reflex center. |
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http://www.wipo.int/cgi-pct/guest/getbykey5?KEY=05/16930.050224&ELEMENT_SET=DECL
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| | Hydromorphone Hydrochloride |
| | Opioids such as hydromorphone relieve pain by acting on specific areas of the spinal cord and brain that process pain signals from nerves throughout the body. | | | This drug may be used by young patients. | | | You should take it as prescribed for the full treatment period, but you may stop taking the drug if you are feeling better before the scheduled end of therapy. |
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http://www.wholehealthmd.com/refshelf/drugs_view/1,1524,303,00.html
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| | Hydromorphone Drug Information |
| | Adults-Long-acting forms of hydromorphone are usually used for patients who have already been receiving narcotics to relieve pain. | | | Buprenorphine and codeine did not cause birth defects in animal studies, but they caused other unwanted effects. | | | Also, unusual excitement or restlessness may be more likely to occur in children receiving these medicines. |
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http://www.drugs.com/cons/Hydromorphone.html
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| | Opiate Agonists |
| | Meperidine hydrochloride for injection is indicated for the relief of moderate to severe pain, as preoperative medication, for the support of anesthesia, and for obstetrical anesthesia. | | | Hydromorphone hydrochloride injection is used to relieve moderate to severe pain and as an adjunct in general anesthesia. | | | Because analgesia equivalency varies among individual patients and specific clinical situations, dosage adjustments will be required. |
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http://www.ashp.org/shortage/drug.cfm?cfid=9574150&CFToken=55039820&id=1065
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| | letter to editor - Lack of Hydrocodone and Hydromorphone Interference ... |
| | We first developed our method for the extraction of a wide range of drugs from urine for GC–MS analysis in a clinical setting (5), which requires that all of the drugs in a sample be identified, not just the drugs of abuse. | | | The fact that hydrocodone and hydromorphone both chromatographed as single peaks, well away from codeine and morphine retention times, indicates that tautomerization, which would result in the appearance of additional peaks, did not occur with either drug under the mild derivatization conditions of this method. | | | We did not report its ability to identify the various opiates because, at the time, we were unaware that hydromorphone and hydrocodone interference was a problem. |
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http://www.jatox.com/abstracts/1996/jul-aug/269-smith.htm
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| | Erowid Hydromorphone (Dilaudid, Palladone) Vault |
| | Join Erowid and help change the way the world thinks about Psychoactives. | | | Hydromorphone is an opiate, narcotic analgesic, used primarily in the treatment of moderate to severe pain. | | | This may cause the full 24-hour dose, a potentially deadly amount, to be released all at one time. |
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http://www.erowid.org/pharms/hydromorphone/hydromorphone.shtml
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| | Dilaudid, Hydromorphone hydrochloride, side effects, drug interactions, overdose, dosage |
| | Dilaudid, a narcotic analgesic, is prescribed for the relief of moderate to severe pain such as that due to: | | | Dilaudid, Hydromorphone hydrochloride, side effects, drug interactions, overdose, dosage | | | If you suspect an overdose, seek emergency medical treatment immediately. |
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http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/dil1137.shtml
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| | HYDROMORPHONE (Injection) |
| | You should not use hydromorphone if you have lung or breathing problems, or if you have an injury or wound inside your skull. | | | There may be other brand names for this medicine. | | | You should not use this medicine if you have ever had an allergic reaction to hydromorphone or to related narcotic pain-killers. |
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http://www.medformation.com/ac/mm_qd.nsf/qd/dnx0666.htm
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| | Cancerquest: Hydromorphone |
| | Alcohol can intensify some of the mental and emotional side effects of hydromorphone, such as drowsiness and changes in mood. | | | This may result in a potentially dangerous slowing of a patient's breathing rate. | | | With prolonged use, tolerance may also become a problem, requiring higher dosages to achieve pain relief. |
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http://www.cancerquest.org/printfriendly.cfm?printpage=1332
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| | An Omnipresent Risk of Morphine-Hydromorphone Mix-ups |
| | The error may have contributed to the patient's death. | | | If both drugs are available in patient care units, avoid stocking morphine and hydromorphone in the same strength. | | | By then, the patient's condition had deteriorated, and he arrested a short time later. |
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http://www.ismp.org/MSAarticles/morphine.htm
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| | Erowid Hydromorphone Vault : Drug Tests |
| | Hydromorphone does not show up in the basic opiate test which is part of the standard pre-employment drug test. | | | As with most substances, hydromorphone is possible to test for, but this is extremely uncommon. | | | Hydromorphone does not break down into morphine, therefore it is not detected. |
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http://www.erowid.org/pharms/hydromorphone/hydromorphone_testing.shtml
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| | Hydromorphone |
| | It is prescribed both as an antitussive and analgesic. | | | Hydromorphone is a semisynthetic narcotic and analgesic that is available in a variety of forms for oral, parenteral and rectal administration typically in doses of 1 — 4 mg as the hydrochloride. | | | About 6% of a dose is excreted as free and 30% as conjugated hydromorphone in a 24 hour. |
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http://www.sdrl.com/druglist/hydromorphone.html
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| | hydromorphone - OneLook Dictionary Search |
| | hydromorphone : The On-line Medical Dictionary [home, info] | | | hydromorphone : Dictionary of Cancer Terms [home, info] | | | hydromorphone : Breast Cancer Talking Dictionary [home, info] |
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http://www.onelook.com/?w=hydromorphone&ls=a
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| | A Hydromorphone and Ethanol Fatality |
| | A case report is presented of a fatality where death is attributed to the combined central nervous system-depressing effects of ethanol and hydromorphone. | | | Blood and tissue levels of hydromorphone are reported and the concentrations are compared to previously reported data. | | | alcohol, forensic science, hydromorphone, pathology and biology, toxicology |
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http://www.astm.org/JOURNALS/FORENSIC/PAGES/477.htm
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| | (WO 00/18378) SUSTAINED RELEASE HYDROMORPHONE FORMULATIONS EXHIBITING BIMODAL CHARACTERISTICS [Repub: 19.07.2001] |
| | (57) The invention is related to a biphasic solid sustained release once-a-day oral dosage form comprising hydromorphone or a pharmaceutically acceptable salt thereof together with a sustained release carrier, and to the use thereof in the treatment of human patients. | | | The dosage provides a rise in plasma concentration to an initial early peak concentration, followed by a second peak with plateau plasma concentrations. | | | (WO 00/18378) SUSTAINED RELEASE HYDROMORPHONE FORMULATIONS EXHIBITING BIMODAL CHARACTERISTICS [Repub: 19.07.2001] |
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http://wipo.int/cgi-pct/guest/getbykey5?KEY=00/18378.010719&ELEMENT_SET=DECL
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| | Procedure Hydromorphone |
| | To request Hydromorphone, order a comprehensive drug screen, urine. | | | Hydromorphone is a member of the following panels : |
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http://health.ucsd.edu/labref/P68.html
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