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| | Stem cell transplantation (SCT) is a life saving procedure... |
 | | The majority of patients who have undergone SCT will lead productive lives in their own towns and any complications will have to be managed initially by the local physicians. | | | The conventional myeloablative therapy given before infusion of bone marrow causes organ toxicity, in addition to myelotoxicity. | | | The mortality as a consequence of this phase may vary from 10-20%. |
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http://www.indegene.com/Main/Issues/indIssues16.asp
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| | Arthritis Research & Therapy Full text Immune ablation and stem-cell therapy in autoimmune disease: Immunological ... |
| | Age (which is associated with diminished thymopoiesis) and the extent of T-cell depletion (by in vivo or ex vivo manipulation of the graft or by [myelo]lymphoablation) are the major determinants of the relative contributions of these sources to the recovery of T-lymphocyte population after HDIT and SCT [5**]. | | | From a critic's viewpoint, eradication of autoreactive memory T and B lymphocytes by autologous SCT may be impossible, and allogeneic SCT may be necessary to achieve this goal. | | | In another study [33**], a patient with RA was treated with a myeloablative conditioning regimen, followed by SCT that was T-cell depleted and CD34 |
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http://arthritis-research.com/content/2/4/270
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| | Allogeneic stem cell transplantation using cord blood stem cells |
| | Recently, we have performed an analysis comparing outcomes of 98 adults patients with acute leukaemia receiving an unrelated cord blood with 584 adults patients receiving a HLA matched unrelated bone marrow in Eurocord centers after 1998. | | | The most important results showed by our group were the decreased incidence of acute and chronic graft-versus-host disease, compared to bone marrow transplants. | | | Further analyses showed that the influence of number of cells in cord blood and of the degree of HLA disparity were mutually interacting on engraftment. |
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http://www.celltherapy.org/Abstracts2003/Speakers/SA012.htm
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| | Tuberculosis in Pakistan: Are We losing the battle? |
| | It was in 1939 when the first patient was infused 18 ml of marrow from his brother for cure of aplastic anemia.3 The subsequent identification of HLA antigens, development of cryobiology techniques and better understanding of human immune system lead BMT to a definitive form of therapy for many malignant and benign hematological disorders. | | | Successful engraftment of cryopreserved autologus bone marrow in patients with malignant lymphoma. | | | Haematopoietic stem cell transplantation remains the treatment of choice for a variety of benign and malignant blood disorders.1 In this modality Haematopoietic stem cell transplantation is the intravenous infusion of haematopoietic stem and progenitor cells to re-establish marrow function in patients with damaged or defective marrow. |
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http://jpma.org.pk/JPMA/9sep03/edit.html
(1054 words)
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| | Articles |
| | Novitzky N, Thomas V, Stubbings H. Intensified myeloablative therapy and autologous stem-cell transplantation for patients with AML: single center experience. | | | Novitzky N, Jacobs P. Immunosupressive therapy in bone marrow aplasia: The stroma functions normally to support hematopoiesis. | | | Alterations in the progenitor cell population follow recovery from myeloablative therapy and bone marrow transplantation Exp Hematol 25 (6), 471-477; 1997. |
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http://web.uct.ac.za/depts/haem/articles.html
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| | Supportive Care -- Wingard et al. 2004 (1): 372 -- Hematology |
| | A model for predicting the outcome of sinusoidal obstruction syndrome (SOS) among patients conditioned with cyclophosphamide-based regimens. | | | Mylotarg (gemtuzumab ozogamicin) therapy is associated with hepatic venoocclusive disease in patients who have not received stem cell transplantation. | | | Support of sinusoidal endothelial cell glutathione prevents hepatic veno-occlusive disease in the rat. |
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http://www.asheducationbook.org/cgi/content/full/2004/1/372
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| | SCDb: The Stem Cell Database |
| | HSC are the best characterized stem cells in the mammal, and have been widely utilized in clinical settings. | | | Stem cell fate decisions are regulated by the complex interplay of cell-autonomous and non-cell-autonomous (instructive) mechanisms. | | | One approach that we have utilized to identify molecular "parts lists" is high-throughput DNA sequence analysis of subtracted cDNA libraries constructed from HSC and an HSC supportive stromal cell line. |
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http://stemcell.princeton.edu
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| | Qasim_abstract |
| | Clinical trials of gene therapy for severe combined immune deficiency (SCID) involving retroviral transduction of haematopoietic stem cells. | | | Molecular mechanism for insertional mutagenesis following gene therapy for X-linked severe combined immune deficiency (SCID-X1). | | | Infants born with severe combined immune deficiencies are prone to life-threatening infections and, without treatment, do not survive beyond the first year of life. |
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http://www-ermm.cbcu.cam.ac.uk/04007884h.htm
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| | Stefan Carlens: Doktorsavhandling från Karolinska Institutet |
| | cells have been termed cytokine-induced natural killer (CINK) cells and may be prepared and used in a DLI setting. | | | Today the major risk of treatment failure is recurrent leukaemia, a risk which has stayed relatively constant over the years. | | | Risk factors in bone marrow transplant recipients with leukaemia. |
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http://diss.kib.ki.se/2000/91-628-4310-9
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| | Donors' stem cells save cancer victims |
| | Doctors say Human Leukocyte Antigens (HLA) proteins located on the surface of white blood cells and other tissues in the body play a critical role in stem cell transplants. | | | So far, nearly 200 patients have had haematopoietic stem cell transplant operations and have restarted their lives as healthy people," said Zhang. | | | Around 200,000 Chinese are ready to give a bit of themselves literally by donating their stem cells to save desperate patients suffering from leukemia. |
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http://www.chinadaily.com.cn/english/doc/2004-11/27/content_395325.htm
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| | Kajsa Larsson: Doktorsavhandling från Karolinska Institutet |
| | Since the start of treatment with allogeneic haematopoietic stem cell transplantation (SCT), cytomegalovirus (CMV) has been one of the most feared complications. | | | CMVR has become four times more common after 1996, and risk factors for its development were CMV-negative donor, CMV-positive recipient, and the use of antiviral CMV-prophylaxis. | | | Human herpesvirus 6 infection and cytomegalovirus-specific lymphoproliferative responses in allogeneic stem cell transplant recipients. |
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http://diss.kib.ki.se/2004/91-7349-735-5
(716 words)
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| | Energy Citations Database (ECD) - Energy and Energy-Related Bibliographic Citations |
| | Availability information may be found in the Availability, Publisher, Research Organization, Resource Relation and/or Author (affiliation information) fields and/or via the "Full-text Availability" link. | | | MICE/radiation effects on survival of bone marrow stem cells of, protective effects of cysteine against x;CELLS/radiation effects on survival of mouse bone marrow stem, protective effects of cysteine against x;X RADIATION/effects on survival of mouse bone marrow stem cells, protective effects of cysteine against;CYSTEINE/radioprotective effects of, on mouse bone marrow stem cells, x | | | For a journal article, please see the Resource Relation field. |
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http://www.osti.gov/energycitations/product.biblio.jsp?osti_id=4722726
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| | Indian Journal of Medical Sciences: Short Tandem Repeat technology has diverse applications: individual identification, ... |
| | Indian Journal of Medical Sciences: Short Tandem Repeat technology has diverse applications: individual identification, phylogenetic reconstruction and chimerism based post Haematopoietic Stem Cell Transplantation graft monitoring.@ HighBeam Research | | | BACKGROUND: Short Tandem Repeat (STR) loci are widely considered to be effective for variety of applications including forensic applications, phylogenetic reconstruction and chimerism based post Haematopoietic Stem Cell Transplantation (HSCT) graft monitoring. | | | Short Tandem Repeat technology has diverse applications: individual identification, phylogenetic reconstruction and chimerism based post Haematopoietic Stem Cell Transplantation graft monitoring. |
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http://www.highbeam.com/library/doc0.asp?DOCID=1G1:121136343&refid=holomed_1
(219 words)
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| | UCT Research Report 2001 - HAEM |
| | Haematopoietic stem cell biology; clonogenic assays; Haematopoietic stem cell transplantation; Immune Reconstitution; Haematological malignancies |
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http://web.uct.ac.za/depts/dri/resrep01/faculties/health/haem/haem03.html
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