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| | Prevalence of HLA-B27.. |
 | | The ankylosing spondilitis and the non granulomatosus alternate bilateral acute anterior uveitis associated to HLA | | | Proceedings: The acute anterior uveitis associated to HLA | | | Fisher accurate test did not showed any significant difference between the negative and positive B27 groups. |
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http://www.imbiomed.com.mx/HG/Hgv61n2/english/Zhg82-01.html
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| | Kimball Genetics - HLA-B27 DNA TEST |
| | This group of disorders is associated with human leukocyte antigen (HLA) B27 suggesting a possible autoimmune etiology. |
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http://www.kimballgenetics.com/tests-hlab27.html
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| | HLA B27 |
| | The research of my group is focused on the role of HLA B27 in these disorders. | | | Homocysteine-specific CTL (Hom-CTL) are present in about 50% of patients and in only 10% of the normal subjects, indicating that they may play an essential role in the development and/or pathogenesis of sera-negative arthropathies. | | | Most of the Hom-CTL identified in B27-positive patients are restricted by B27. |
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http://homepages.which.net/~ks.burrell/nassdb/hlab27.htm
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| | HLA-B27 associated uveitis |
| | The HLA-B27 patients were also more likely than the idiopathic patients to require systemic therapy for the ocular condition, and this was even more so in patients with systemic disease associated with the B27 positive uveitis. | | | Twenty percent of patients with psoriatic arthropathy, (but not the psoriatic skin lesions alone), develop uveitis. | | | Classically, B27 associated uveitis presents with sudden onset acute anterior uveitis in a young patient. |
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http://www.uveitis.org/WebEyeMD_htmbank/md_hlab27.htm
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| | HLA-B27 Misfolding Is Associated with Aberrant Intermolecular Disulfide Bond Formation (Dimerization) in the ... |
| | HLA class I complexes were immunoprecipitated with W6/32 or HC10, separated by SDS-PAGE under nonreducing conditions, and visualized by immunoblotting with 3B10.7. | | | SDS-PAGE of immunoprecipitates was performed under nonreducing (NRed) and reducing (Red) conditions, and immunoblotted with 3B10.7. | | | A, HLA class I complexes were immunoprecipitated with W6/32 from B lymphoblastoid cell lines (B-LCL: HF and BL) expressing HLA-B27 as well as other alleles, and from C1R transfected with different HLA alleles, separated by SDS-PAGE under nonreducing conditions, and HC visualized by immunoblotting with 3B10.7. |
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http://www.jbc.org/cgi/content/full/277/26/23459
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| | Animal Models - HLA-B27 Transgenic Rats |
| | Features: The HLA-B27 transgenic rat, expressing HLA-B27 and human ß2m, exhibits a phenotype similar to humans suffering B27 related rheumatic disorders such as reactive arthritis, ankylosing spondylitis, psoriasis and inflammatory bowel disease. | | | This rat model is useful for research and pharmacological studies of spontaneous systemic inflammation, arthritis, inflammatory bowel disease and skin diseases including psoriasis and alopecia. |
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http://www.taconic.com/anmodels/HLAB27.htm
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| | iritis.com: HLA B27 |
| | HLA's are what the body's immune system uses to keep track of "self" and "non-self". | | | Your doctor may diagnose you as having B27 associated iritis by your symptoms and course. | | | If you have B27 it means you have a statistically higher chance of developing the symptoms of other B27-associated diseases. |
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http://www.iritis.co.uk/b27.htm
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| | The Pathogenetic Role of HLA-B27 |
| | B*2706 is a common subtype among B27 positive individuals in Southeast Asia, while B*2709 is primarily observed in the Italian island of Sardinia. | | | HLA-B27 derived peptides may themselves elicit an immune response if there is loss of immune tolerance. | | | Such cells were not present in B27 positive healthy individuals. |
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http://www.rheuma21st.com/archives/report_050225_hlab27.html
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| | eMedicine - HLA-B27 Syndromes : Article by A Luisa Di Lorenzo, MBBCh |
| | The third theory suggests that the T-cell antigen is the true susceptibility factor, and a fourth theory implicates an innate etiology unrelated to HLA. | | | In ophthalmology, HLA associations are strongest in diseases of the uvea. | | | An HLA disease association is defined as a statistically increased frequency of the HLA haplotype in individuals with the disease compared to the frequency in individuals without the disease. |
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http://www.emedicine.com/OPH/topic721.htm
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| | Reactive arthritis and HLA-B27 - mechanisms - antigen processing - Chlamydia |
| | Popov et al., 2002 explored this question using HLA-B27 transgenic rats expressing human B27 antigen. | | | Nor was it observed if rats were immunised with non-transgenic spleen cells or with a DNA construct expressing a different antigen, HLA-A2. | | | Thus they do not develop a cytotoxic T lymphocyte response to the artificial self [B27] antigen. |
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http://chlamydiae.com/restricted/docs/infections/arthritis_pathogenesis.asp
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| | HLA-B27: Test Sample |
| | (This is important when someone needs a bone marrow or organ transplant, as the donor’s HLA antigens must be matched up with the recipient’s.) | | | Its presence has been associated with several autoimmune disorders. | | | While not as unique as a fingerprint, the presence or absence of each antigen creates a distinctive HLA combination for each person. |
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http://www.labtestsonline.org/understanding/analytes/hla_b27/sample.html
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| | HLA-B27 |
| | Approximately 85% of patients with ankylosing spondylitis and Reiter's syndrome will have the HLA-B27 antigen present on the leukocytes. | | | This test determines a person's major histocompatibility antigens on the surface of their lymphocytes. | | | Some HLA antigens have been identified to be correlated with the presence of certain autoimmune diseases. |
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http://www.medhelp.org/glossary/new/gls_2284.htm
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| | MedlinePlus Medical Encyclopedia: HLA-B27 antigen |
| | For example, HLA-B27 is found in 80 - 90% of people with ankylosing spondylitis and Reiter's syndrome. | | | Many HLA antigens exist, but some are of special interest since they are more common in certain autoimmune diseases. | | | The human leukocyte antigens (HLAs) are proteins present on the surface of all body cells that contain a nucleus, and are in especially high concentrations in white blood cells (leukocytes). |
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http://www.nlm.nih.gov/medlineplus/ency/article/003551.htm
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| | Medcyclopaedia - Hla-b27 antigen |
| | Among the conditions in which HLA-B27 antigen may play a causative role are ankylosing spondylitis, psoriatic arthritis, Reiters syndrome, Crohns disease and ulcerative colitis. | | | a histocompatibility antigen of the HLA group that is found in many diseases with musculoskeletal manifestations. |
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http://medcyclopaedia.com/library/topics/volume_iii_1/h/HLA_B27_ANTIGEN.aspx
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| | HLA-B27 - Wikipedia, the free encyclopedia |
| | HLA B27 in health and disease: a double-edged sword? | | | It presents microbial antigens to T-cells and is strongly associated with certain immunity diseases (SpA spondyloarthropathies). | | | Human Leukocyte Antigen B*27 (subtypes B*2701-2724) is a class I surface antigen encoded by the B locus in the MHC on chromosome 6. |
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http://en.wikipedia.org/wiki/HLA-B27
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| | AFCG Clinical Standards: HLA-B27 |
| | Problems may arise, however, when antibody cross-reactivity occurs between different HLA antigens. | | | The development of monoclonal antibodies to HLA antigens has rendered flow cytometry a proficient alternative procedure. | | | The early clones suffered because of their cross-reactivity with other HLA antigens, especially HLA-B7. |
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http://jcsmr.anu.edu.au/facslab/AFCG/Standards/hla-b27.html
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| | HLA-B27 - Information and Side Effects |
| | Consult a physician regarding the applicability of any information found on GoldBamboo.com to your symptoms or medical condition. | | | This test is sometimes ordered to help assess the likelihood that you have an autoimmune disorder that is associated with the presence of HLA-B27. | | | To determine whether you have human leukocyte antigen B27 (HLA-B27) on the surface of your cells. |
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http://goldbamboo.com/topic-t4276.html
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| | health.iafrica.com doc online ask the doctor musculoskeletal Hla b27 |
| | The HLA B27 antigen is closely associated with the inflammatory disorder, ankylosing spondylitis. | | | Since your son has the peripheral joint involvement which is one of the characteristics of this disease, he probably has early signs of the illness. | | | He has very inflamed fingers and feet and none of his medicines are helping. |
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http://health.iafrica.com/doconline/qa/musculoskeletal/hlab27.htm
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| | Ankylosing spondylitis - Genetics Home Reference |
| | HLA-B is part of a family of genes called the human leukocyte antigen (HLA) complex. | | | The HLA complex helps the immune system distinguish the body's own proteins from proteins made by foreign invaders (such as viruses and bacteria). | | | The HLA-B gene has many different normal variations, allowing each person's immune system to react to a wide range of foreign invaders. |
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http://0-ghr.nlm.nih.gov.portia.nesl.edu/condition=ankylosingspondylitis/sho...
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| | Energy Citations Database (ECD) - Energy and Energy-Related Bibliographic Citations |
| | Availability information may be found in the Availability, Publisher, Research Organization, Resource Relation and/or Author (affiliation information) fields and/or via the "Full-text Availability" link. | | | For a journal article, please see the Resource Relation field. | | | Complete sequence of HLA-B27 cDNA identified through the characterization of structural markers unique to the HLA-A, -B, and -C allelic series |
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http://www.osti.gov/energycitations/product.biblio.jsp?osti_id=5563011
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