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Topic: Growth factor


  
 Synthetic Growth Factor Technology
It also has been evaluated in clinical trials in the U.S. for its ability to enhance neurological recovery after stroke and to minimize the effects of ischemia, or insufficient blood flow in the heart and circulatory system.
Paul Zamora, BioSET’s chief scientific officer, said, “We view this as a platform technology to develop analogs to many types of growth factors of current clinical interest, including those used to accelerate bone repair, treat ischemic tissue and wound healing.
Our studies show that the FGF analogs are active and biologically equivalent to natural FGF, and that they work in animal models of human disease.
http://www.bnl.gov/bnlweb/pubaf/pr/2002/bnlpr121702.htm   (725 words)

  
 Insulin-like Growth Factor-1 Therapy in Diabetes: Physiologic Basis, Clinical Benefits, and Risks -- Kolaczynski and ...
Structure of the human insulin-like growth factors: Relationship to function.
Insulin-like Growth Factor-1 Therapy in Diabetes: Physiologic Basis, Clinical Benefits, and Risks -- Kolaczynski and Caro 120 (1): 47 -- Annals of Internal Medicine
under certain circumstances the growth response may be mediated
http://www.annals.org/cgi/content/full/120/1/47   (6707 words)

  
 Keratinocyte Growth Factor Enhances Post-Pneumonectomy Lung Growth by Alveolar Proliferation -- Kaza et al. 106 (12 ...
on lung growth after pneumonectomy and not on sham animals.
The rats used in our study were adult rats that were 7 to 8
This suggests that there was a specific affect of KGF
http://circ.ahajournals.org/cgi/content/full/106/12_suppl_1/I-120   (3297 words)

  
 GFM Pro - Look younger, feel better, and improve performance - Growth Factor Matrix - anti-aging, performance and ...
This is what we call the Growth Factor Matrix, enabling us to develop products targeting key areas of health.
With this breakthrough, Nutritec is able to offer targeted formulations aimed at stopping and reversing aging, boosting athletic performance, and improving skin condition.
However, our scientists have taken this a crucial step further, having learned not only what the active ingredients do, but how they interact.
http://www.gfmpro.com   (529 words)

  
 Effect of single wrist exercise on fibroblast growth factor-2, insulin-like growth factor, and growth hormone -- ...
Increased expression of fibroblast growth factors in a rabbit skeletal muscle model of exercise conditioning.
The mechanism of the marked reduction in circulating FGF-2 after unilateral wrist-flexion exercise is not readily apparent.
In this study, brief, unilateral exercise of small muscle groups significantly altered circulating levels of a number of growth
http://ajpregu.physiology.org/cgi/content/full/279/2/R548   (3811 words)

  
 Insulin-like growth factor in muscle growth and its potential abuse by athletes -- Adams 34 (6): 412 -- British Journal ...
factor treated rats would actually be less well adapted to normal
of hypoxia on rat growth suggests that it is, in fact, the impact
Effect of growth hormone therapy in mitigating hypoxia-induced and food restriction-induced growth retardation in the newborn rat.
http://bjsm.bmjjournals.com/cgi/content/full/34/6/412   (1000 words)

  
 Insulin-like Growth Factor-1 Receptor in Uveal Melanoma: A Predictor for Metastatic Disease and a Potential Therapeutic ...
behavior and regarding its role in growth and survival of uveal
From our study we can also conclude that growth and survival
Dricu, A, Kanter, L, Wang, M, et al (1999) Expression of the insulin-like growth factor 1 receptor (IGF-1R) in breast cancer cells: evidence for a regulatory role of dolichyl phosphate in the transition from an intracellular to an extracellular IGF-1 pathway Glycobiology 9,571-579
http://www.iovs.org/cgi/content/full/43/1/1   (4482 words)

  
 Heparin-binding EGF-like Growth Factor Is an Autocrine Growth Factor for Human Urothelial Cells and Is Synthesized by ...
Statistical analysis for the MTT assay and the
As with skin, the urothelium is capable of rapid regenerative
Folkman(1993)Elevated levels of the angiogenic peptide basic fibroblast growth factor in urine of bladder cancer patients.
http://www.jci.org/cgi/content/full/99/5/1028   (6309 words)

  
 Growth Factor 1 (GF-1) Natural anabolic hormone
Women interested in simply toning their bodies should not use this product.
Growth Factor-1 is a safe, effective, legal muscle builder.
Growth Factor-1 has allowed me to experience a level of growth that I thought was only possible through the use of steroids.
http://www.thepumpingstation.com/growthfactor1.html   (901 words)

  
 Fibroblast Growth Factors
If you have areas you don’t understand, comments (good or bad), or if you have a specific health concern, feel free to write to me by clicking here.
FGF is a group of GFs that act on the fibroblast within the body.
Due to its stimulatory effect on fibrous tissues, active cancer or pregnant patients should avoid taking this as a food supplement unless cleared by a physician.
http://www.drlam.com/A3R_brief_in_doc_format/fibroblast_growth_factors.cfm   (1247 words)

  
 Insulin-like Growth Factor-1
The body is comprised of many systems that work together.
This site has not been evaluated by the FDA, the information and products are not meant as a prevention, treatment or cure for any health condition, please consult your private healthcare provider.
IGF-1 is 10 times more potent than HGH, some researchers and clinicians believe that it can be more effective and more potent than growth hormone.
http://www.hgh-pro.com/igf-1.html   (530 words)

  
 Hepatocyte Growth Factor/Scatter Factor Can Induce Angiogenesis Independently of Vascular Endothelial Growth Factor -- ...
Xe clearance, blood flow and histology in the rat scaffold model for angiogenesis: further studies with angiogenic modifiers.
The Effect of Growth Factor and Drug Treatments on the T
The concentration-effect response of the VEGFR inhibitor, PTK787, on VEGF- and HGF/SF-induced MAPK (ERK1 and ERK2) and Akt activation, as determined by Western blot analysis with anti-phospho ERK and anti-phospho Akt antibodies.
http://atvb.ahajournals.org/cgi/content/full/23/1/69   (3750 words)

  
 Recombinant Human Growth Hormone, Insulin-like Growth Factor 1, and Combination Therapy in AIDS-Associated Wasting: A ...
This lack of a linear association between physical changes of
Effects of growth factor therapy on immunologic function and
increases with growth factor therapy (that is, collagen or skeletal
http://www.annals.org/cgi/content/full/125/11/865   (5041 words)

  
 Scatter Factor/Hepatocyte Growth Factor Stimulation of Glioblastoma Cell Cycle Progression through G1 Is c-Myc ...
To confirm that SF/HGF was mediating a posttranscriptional change
Signaling pathways in the induction of c-met receptor expression by its ligand scatter factor/hepatocyte growth factor in human glioblastoma.
Immunoreactive hepatocyte growth factor is a strong and independent predictor of recurrence and survival in human breast cancer.
http://mcb.asm.org/cgi/content/full/22/8/2703   (7289 words)

  
 No Evidence of Insulin-Like Growth Factor-Binding Protein 3 Proteolysis during a Maximal Exercise Test in Elite ...
growth factor (IGF) axis, post exercise, with emphasis on IGF-binding
The aim of the present study was to examine the GH/insulin-like
1995 Testosterone, growth hormone and IGF-I responses to acute and chronic resistive exercise in men aged 55–70 years.
http://jcem.endojournals.org/cgi/content/full/86/2/669   (3918 words)

  
 Expression of Insulin-Like Growth Factor I Messenger Ribonucleic Acid in Developing Osteophytes in Murine Experimental ...
This evidence suggests that other factors seemed to be directly
inflammatory factors may be involved in the stimulation of the
bone growth (5, 6, 7, 8, 9, 10, 11, 12).
http://endo.endojournals.org/cgi/content/full/140/10/4821   (4741 words)

  
 Role of Vascular Endothelial Growth Factor in Ovarian Cancer : Inhibition of Ascites Formation by Immunoneutralization ...
express other angiogenic factors, the specific role of VEGF
Vascular Permeability Factor/Vascular Endothelial Growth Factor: A Critical Cytokine in Tumor Angiogenesis and a Potential Target for Diagnosis and Therapy
in the growth and progression of ovarian cancer is unclear.
http://ajp.amjpathol.org/cgi/content/full/153/4/1249   (5893 words)

  
 Insulin-like growth factor - Wikipedia, the free encyclopedia
Almost every cell in the human body is affected by IGF-1, especially cells in muscle, cartilage, bone, liver, kidney, nerves, skin, and lungs.
While IGF-2 may be primarily fetal in action it is also essential for development and function of organs such as the brain, liver and kidney.
IGFs are part of a complex system that cells use to communicate with their physiologic enviornment.
http://en.wikipedia.org/wiki/Insulin-like_growth_factor   (653 words)

  
 Growth factor - Wikipedia, the free encyclopedia
For the last two decades growth factors have been increasingly used in treatment of hematologic and oncologic diseases like:
The names of individual growth factors often have little to do with their most important functions and exist due to the historical cirumstances under which they arose.
However, as different lines of research converged, it became clear that some of the same signalling proteins the hematopoietic and immune systems used were also being used by all sorts of other cells and tissues, during development and in the mature organism.
http://en.wikipedia.org/wiki/Growth_factor   (618 words)

  
 IGF1 - Insulin-like growth factor 1 (somatomedin C) - Cancer GeneticsWeb
Plasma levels of insulin-like growth factor-I and lung cancer risk: a case-control analysis.
Insulin-like growth factor 1 and prostate cancer risk: a population-based, case-control study.
Cancer and insulin-like growth factor-I. A potential mechanism linking the environment with cancer risk.
http://www.cancerindex.org/geneweb/IGF1.htm   (445 words)

  
 Growth Factors and Cytokines
family of growth factors and associated signaling pathways can be found on the Signaling by Wnts and TGFs-
Studies of human disorders as well as gene knock-out studies in mice show the prominent role for FGFs is in the development of the skeletal system and nervous system in mammals.
induces the expression of other autocrine growth factors, increases cellular responsiveness to growth factors and induces signaling pathways that lead to proliferation.
http://www.indstate.edu/thcme/mwking/growth-factors.html   (2547 words)

  
 Pure IGF (Natural growth factor dietary supplement)
The actions of growth factors are the restoration of normal body processes and strengthening of the body, possibly leading to mental and physical performance increases and enhancement of the immune system.
These naturally occuring growth factors are involved in every cellular function in the human body from metabolism to the human response.
Pure IGF directly supplements the growth factors that are the key to age related symptoms.
http://www.pureigf.com/pureigf.htm   (165 words)

  
 growth factor - definition of growth factor in the Medical dictionary - by the Free Online Medical Dictionary, ...
A substance that affects the growth of an organism.
This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional.
growth factor - definition of growth factor in the Medical dictionary - by the Free Online Medical Dictionary, Thesaurus and Encyclopedia.
http://medical-dictionary.thefreedictionary.com/growth+factor   (82 words)

  
 Insulin-Like Growth Factor 1 (IGF-1)
Carro E, Nuñez A, Busiguina S, Torres-Aleman I. Circulating insulin-like growth factor 1 mediates effects of exercise on the brain.
Insulin-like growth factor-1: potential for treatment of motor neuronal disorders.
Plasma insulin-like growth factor 1 and prostate cancer risk: a prospective study.
http://www.pdrhealth.com/drug_info/nmdrugprofiles/nutsupdrugs/ins_0303.shtml   (637 words)

  
 Growth Factor Raises Cancer Risk
High levels of a well-known growth factor significantly increase the risks of colorectal, breast, and prostate cancer, medical researchers have found.
"If further studies confirm these findings, blood levels of the growth factor and its binding protein might be used to identify people at the highest risk for these cancers and, therefore, who might benefit most from lifestyle changes and other means of prevention," says Jing Ma, an instructor in medicine at Harvard Medical School.
In children, the hormone stimulates bone growth and development of organs such as the heart, liver, and kidneys.
http://www.news.harvard.edu/gazette/1999/04.22/igf1.story.html   (1261 words)

  
 ScienceDaily: Growth Factor Receptor Signaling Critical To Intestinal Tumor Development, Studies Show
Their work also suggests that a drug or genetic manipulation that inhibits the receptor's chemical signaling machinery should help treat advanced colorectal cancers in humans one day.
Working with laboratory mice, the researchers found that a molecule called epidermal growth factor receptor (Egfr) is necessary for most intestinal tumors to form.
Growth Factor Receptor Signaling Critical To Intestinal Tumor Development, Studies Show
http://www.sciencedaily.com/releases/2002/01/020130073603.htm   (1085 words)

  
 Temporal and spatial expression of connective tissue growth factor (CCN2; CTGF) and transforming growth factor {beta} ...
Activation-dependent adhesion of human platelets to Cyr61 and Fisp12/mouse connective tissue growth factor is mediated through integrin alpha(IIb)beta(3).
The angiogenic factors cyr61 and connective tissue growth factor induce adhesive signaling in primary human skin fibroblasts.
Connective tissue growth factor: a mediator of TGF-beta action on fibroblasts.
http://mp.bmjjournals.com/cgi/content/full/55/3/186   (4570 words)

  
 Increased Vascular Endothelial Growth Factor Serum Concentrations May Help to Identify Patients with Onset of Type 1 ...
The present study shows that patients with increased VEGF serum concentrations
serum concentrations may be one of the predictors and risk factors
1997 Vascular dysfunction induced by elevated glucose levels in rats is mediated by vascular endothelial growth factor.
http://jcem.endojournals.org/cgi/content/full/86/8/3871   (3911 words)

  
 Receptors
There are at least several hundred distinct receptor: ligand pairs in our body, each devoted to the binding of a distinct extracellular ligand such as a growth factor to its cognate receptor.
This extracellular receptor domain can be viewed as having a pocket that specifically accommodates the appropriate growth factor in a lock-and-key fashion and at the same time excludes all others.
Such transmission of information by a protein is often termed by biochemists as a form of signal transduction.
http://web.mit.edu/esgbio/www/cb/membranes/gf.html   (993 words)

  
 Vascular endothelial growth factor (VEGF) definition - Medical Dictionary definitions of popular medical terms
VEGF is a polypeptide structurally related to platelet-derived growth factor (PDGF).
Vascular endothelial growth factor (VEGF) definition - Medical Dictionary definitions of popular medical terms
Please consult your healthcare provider before beginning any course of supplementation or treatment.
http://www.medterms.com/script/main/art.asp?articlekey=5963   (190 words)

  
 Palifermin (Keratinocyte Growth Factor) Information Page
Palifermin is used to reduce the chances of developing severe mucositis (injury to the cells lining the mouth) and to shorten the time with severe mucositis in patients with cancer who receive high doses of chemotherapy and radiation therapy followed by stem cell rescue.
FDA approves Palifermin, a modified version of a naturally occurring human protein called keratinocyte growth factor (KGF) that is manufactured in a laboratory.
Date created: December 15, 2004, updated July 29, 2005
http://www.fda.gov/cder/drug/infopage/palifermin   (76 words)

  
 The selective epidermal growth factor receptor tyrosine kinase inhibitor PD153035 suppresses expression of ...
this study is to evaluate the ability of the epidermal growth
factor receptor-dependent signaling might be a useful strategy
The selective epidermal growth factor receptor tyrosine kinase inhibitor PD153035 suppresses expression of prometastasis phenotypes in malignant pleural mesothelioma cells in vitro -- Cole et al.
http://jtcs.ctsnetjournals.org/cgi/content/abstract/129/5/1010   (330 words)

  
 nerve growth factor - definition of nerve growth factor in Encyclopedia
nerve growth factor - definition of nerve growth factor in Encyclopedia
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http://encyclopedia.laborlawtalk.com/nerve_growth_factor   (52 words)

  
 Cell Growth & Differentiation
Copyright © 2006 by the American Association of Cancer Research.
For faster access to CG&D Online from these locations use this URL:
Complete Back Issues of Cell Growth & Differentiation (January 1990-September 2002) Now Available Online
http://cgd.aacrjournals.org   (61 words)

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