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| | USP Continuing Education - Therapeutic and Adverse Effects of Glucocorticoids - Title |
 | | Increased triglycerides and cholesterol are associated with glucocorticoid therapy. | | | Intermediate-acting glucocorticoids, such as prednisone, are most appropriate for alternate-day therapy. | | | All patients requiring long-term glucocorticoid therapy are candidates for osteoporosis prevention. |
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http://www.uspharmacist.com/NewLook/CE/glucocort/lesson.htm
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| | Management of Postoperative Pain - Glucocorticoids |
| | Glucocorticoids used before or after neurosurgery for cerebral tumors, spinal metastases, head injuries, or acute spinal cord injury may indirectly relieve pain by reducing cerebrospinal fluid formation or tissue edema. | | | Systemic or intra-articular administration of glucocorticoids before or immediately after arthroscopic surgery (Rasmussen et al., 1998; Wang et al., 1998), lumbar disc surgery (King, 1984; Watters et al., 1989), bunion surgery (Curda, 1983), or hallux valgus correction (Asaboe et al., 1998) is effective in reducing pain or reducing the use of narcotic analgesics postoperatively. | | | Complications associated with nonsurgical use of epidural glucocorticoids include infection, dural tap, transient headache, and transient increase in pain (Carette et al., 1997). |
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http://www.oqp.med.va.gov/cpg/PAIN/pain_cpg/content/Pharmac/glucocorticoids.htm
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| | Glucocorticoid - Clinical Pharmacology |
| | Differences between glucocorticoid drugs are potency, duration of action of the base, and pharmacokinetic behavior of the salts. | | | Glucocorticoids appear to have activities that are mediated through alternate pathways. | | | All glucocorticoid drugs act by the same basic mechanism. |
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http://cpharm.vetmed.vt.edu/vm8784/GLUCOCORTICOIDS/glucocort.htm
(841 words)
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| | Use of Anabolic Steroids to Attenuate the Effects of Glucocorticoids on the Rat Diaphragm |
| | The purpose of this study was to assess the effects of simultaneous administration of testosterone and glucocorticoids on morphological and contractile properties of the rat diaphragm. | | | Administration of glucocorticoids results in atrophy and contractile dysfunction in the rat diaphragm. | | | Detrimental effects of short-term glucocorticoid use on the rat diaphragm. |
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http://www.ptjournal.org/PTJournal/Jan2003/v83n1p29.cfm
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| | Glucocorticoids, I3 |
| | As such, long-term anti-inflammatory therapy with glucocorticoids can often lead to swelling, skin changes, decreased immunity, and psychological changes. | | | Rather, the study suggests that testing of other anti-inflammatory compounds such as NSAIDs (examples include aspirin and ibuprofen) or selective COX-2 inhibitors (examples include rofecoxib and celecoxib) is critical in the search for the right combination of therapies for AD. | | | Externally, it is used extensively as a cream or lotion for skin conditions such as rashes or itches. |
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http://www.stanford.edu/group/hopes/treatmts/antinflm/i3.html
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| | FindArticles search for "Glucocorticoids" |
| | Balancing the Immune Response Glucocorticoids are the most important immunosuppressive agents in medicine; they are an established therapy for a great... | | | Study objectives: Inhaled glucocorticoids (GCs) are the most effective control therapy for asthma. | | | Factors influencing the responsiveness to inhaled glucocorticoids of patients with moderate-to-severe asthma |
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http://www.findarticles.com/p/search?tb=art&qt=Glucocorticoids
(496 words)
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| | [Glucocorticoids and infection] |
| | To analyze the effect of glucocorticoids prescribed as adjuvants in patients with infectious diseases, an analysis of the controlled trials was performed. | | | In the following review important mechanisms of action of glucocorticoids on the immunological network are summarized, the relationship between duration of therapy, daily dose and incidence of infections is analysed, and evidence is presented that in some infectious diseases glucocorticoids may even be beneficial. | | | On the other hand, there is no evidence that patients with septic shock or ARDS derive advantage from glucocorticoid therapy. |
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http://www.aegis.com/aidsline/1992/may/M9250288.html
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| | AJRCCM -- Year in Review : Glucocorticoids |
| | Because glucocorticoids can affect matrix metalloproteinases, Choe and coworkers studied the effect of methylprednisolone on lung structure in adult rats. | | | The rate of readmission or death was affected markedly by the time available for receiving a glucocorticoid prescription in the time-fixed analysis; this effect was not observed with the corrected, time-dependent analysis. | | | In a state of the art review article on disorders of the respiratory muscles, Laghi and Tobin discuss the effect of COPD on the respiratory muscles. |
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http://ajrccm.atsjournals.org/cgi/collection/copd84
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| | Antenatal Glucocorticoids and Programming of the Developing CNS -- MATTHEWS 47 (3): 291 -- Pediatric Research |
| | Ajilore OA, Sapolsky RM 1999 In vivo characterization of 11ß-hydroxysteroid dehydrogenase in rat hippocampus using glucocorticoid neuroendangerment as an endpoint. | | | Lupien SJ, McEwen BS 1997 The acute effects of corticosteroids on cognition: integration of animal and human model studies. | | | Anisman H, Zaharia MD, Meaney MJ, Merali Z 1998 Do early-life events permanently alter behavioral and hormonal responses to stressors? |
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http://www.pedresearch.org/cgi/content/full/47/3/291
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| | Glucocorticoids - The Merck Veterinary Manual |
| | For chronic therapy in small animals, oral prednisone is usually the drug of choice. | | | Studies suggest glucocorticoids enhance the action of adrenergic agonists on β | | | Cats are somewhat resistant to the effects of glucocorticoids, and dosages of prednisone of 1.0 mg/kg/day may be necessary for chronic therapy of feline asthma. |
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http://www.merckvetmanual.com/mvm/htm/bc/190906.htm
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| | The Adrenal Glands |
| | For this reason glucocorticoids are widely used in therapy: | | | Fortunately, replacement therapy with glucocorticoids and mineralocorticoids can permit a normal life. | | | as a result of glucocorticoid therapy for some other disorder such as |
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http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/A/Adrenals.html
(696 words)
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| | glucocorticoids |
| | Glucocorticoids have a wide variety of functions in the body. | | | Creams, lotions - skin rash due to allergy, hypersensitivity ie poison ivy | | | Patients may need additional glucocorticoids during stress situations such as surgery. |
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http://www.atwork.loyalistc.on.ca/niblett/glucocorticoids.html
(432 words)
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| | Glucocorticoids and Croup |
| | Meta-analysis of 24 randomized, controlled studies support the use of glucocorticoids for treatment of croup. | | | In pediatric patients with croup, are glucocorticoids more effective than placebo in improving symptoms? | | | Glucocorticoids Are Effective in Decreasing Croup Symptoms In Children |
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http://www.med.umich.edu/pediatrics/ebm/cats/croup.htm
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| | Interactions between GH, IGF-I, Glucocorticoids, and Thyroid Hormones during Skeletal Growth -- ROBSON et al. 52 (2): ... |
| | Canalis E 1996 Clinical review 83: Mechanisms of glucocorticoid action in bone: implications to glucocorticoid-induced osteoporosis. | | | Allen DB 1996 Growth suppression by glucocorticoid therapy. | | | LoCascio V, Bonucci E, Imbimbo B, Ballanti P, Adami S, Milani S, Tartarotti D, DellaRocca C 1990 Bone loss in response to long-term glucocorticoid therapy. |
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http://www.pedresearch.org/cgi/content/full/52/2/137
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| | Cushing syndrome secondary to topical glucocorticoids |
| | Erythrodermic psoriasis associated with hyperuricemia and iatrogenic Cushing's syndrome due to topical corticosteroid therapy. | | | Topical glucocorticoids were discontinued, and he was started on calcipotriene (0.005 %) ointment for his body, ketoconazole (2 %) cream for his face, and ketoconazole (2 %) shampoo for his scalp; he also was started on adapalene (0.1 %) gel for his axillary striae. | | | Cushing syndrome is most commonly caused by the therapeutic administration of exogenous systemic glucocorticoids. |
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http://dermatology.cdlib.org/94/NYU/Feb2002/5.html
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| | Management of Postoperative Pain - Glucocorticoids |
| | The more potent glucocorticoids (methylprednisolone, triamcinolone, dexamethasone, and betamethasone) have been the agents most frequently used in studies of postoperative pain control. | | | Glucocorticoids may be given just before or immediately after surgery as single doses or as scheduled, tapering doses over several days postoperatively. | | | For prevention of PONV related to abdominal total hysterectomy, administration of dexamethasone before induction of anesthesia has been shown to be more effective than administration after anesthesia (Wang et al., 2000). |
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http://www.oqp.med.va.gov/cpg/PAIN/pain_cpg/content/Pharmac/tableGC1.htm
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| | PharmGKB: glucocorticoids |
| | Tacrolimus dosing and Steroid Weaning in pediatric heart transplant patients | | | Submitted by: Burckart GJ involving ABCB1, CYP3A4, CYP3A5, glucocorticoids, prednisone, tacrolimus, and Organ Transplantation. | | | Submitted by: Erin G. Schuetz, PhD involving CYP3A4, NR1I2,, amiodarone, cimetidine, dopamine, erythromycin, ethanol, glucocorticoids, midazolam, nicotine, phenobarbital, phenytoin, propofol, statin, thyroid and vasopressin. |
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http://www.pharmgkb.org/views/index.jsp?objCls=Drug&objId=PA452347
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