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Topic: Gastrointestinal stromal tumor


  
 Gastrointestinal Stromal Tumors
Gastric stromal tumors: a clinicopathologic study of 77 cases with correlation of features with nonaggressive and aggressive clinical behaviors.
Gastrointestinal stromal tumors (GISTs) have a wide spectrum of biologic behavior ranging from benign to malignant.
The clinical behavior of gastrointestinal stromal tumors (GIST) is site specific; however, other reliable predictors of clinical outcome have not been identified.
http://www.thedoctorsdoctor.com/diseases/stromal_tumors_gi.htm   (13696 words)

  
 Recent GIST Publications
Imatinib mesylate as therapy for gastrointestinal stromal tumor
A clinical case of duodenal gastrointestinal stromal tumor with a peculiarity in the surgical approach
This paper is not about GIST, but it tests the use of perifosine, a drug which is being tested against GIST in a combination clinical trial at MD Anderson.
http://www.gistsupport.org/blogs/news/recent.html   (2878 words)

  
 eMedicine - Gastrointestinal Stromal Tumors - Leiomyoma/Leiomyosarcoma : Article by Vu Nguyen, MD
Medicine is a constantly changing science and not all therapies are clearly established.
Given the potential malignant behavior of benign appearing GISTs, at least 1 group believes that all GISTs should be classified as malignant tumors on a low-to-high grading scale rather than on a benign-versus-malignant basis (Pierie, 2001).
Findings from 2 studies show that microscopic resection margins are not correlated with improved outcome (Pierie, 2001; DeMatteo, 2000).
http://www.emedicine.com/radio/topic388.htm   (3781 words)

  
 Gastrointestinal Stromal Tumor (GIST)
I also know that if it turns out to be the "right" kind of tumor, Gleevec may be indicated as follow-up/adjunct therapy.
Anyway, like most patients, I am scared and more than a little paranoid, so I'm trying to learn and collect as much information as I can.
But time is of the essence here, and I am VERY much against a biopsy (needle aspiration or otherwise) because I have fears that IF its malignant, tumor seeding and/or spillage may significantly worsen my prognosis.
http://www.medhelp.org/perl6/gastro/messages/36002a.html   (1016 words)

  
 MIR Teaching file case pt076
The experience with this drug in the treatment of GISTs is very encouraging.
FDG-PET can be used to monitor the therapeutic response.
Effect of the tyrosine kinase inhibitor STI571 in a patient with a metastatic gastrointestinal stromal tumor.
http://gamma.wustl.edu/pt076te173.html   (625 words)

  
 Bioline International Official Site (site up-dated regularly)
However, resection of these tumors is necessary, since their behavior is unpredictable and they have to be pathologically examined.
Radiation therapy and chemotherapy have been used to a lesser extent, mainly in a palliative setting.
This tumor is resistant to chemoradiation and adequate surgical resection is the only definitive treatment.
http://www.bioline.org.br/request?is04027   (1482 words)

  
 Gastrointestinal stromal tumor - Wikipedia, the free encyclopedia
American Society of Clinical Oncology "Other Gastrointestinal Cancer" Abstracts (2005)
GIST Info Patient links, includes information on new clinical trials and research
American Cancer Society Patient Guide to GIST tumors.
http://en.wikipedia.org/wiki/Gastrointestinal_stromal_tumor   (1047 words)

  
 eSynopsis of Gastrointestinal Stromal Tumor of the Small Intestine
•While it is difficult to distinguish between some benign mesenchymal tumors and low grade sarcomas, there is no convincing evidence that intestinal sarcomas arise from their benign counterparts.
•Some tumors may be endophytic, bulging into the lumen of the intestine.
•Malignant GIST tumors which are endophytic may present with evidence of obstruction or bleeding.
http://esynopsis.uchc.edu/S166.htm   (448 words)

  
 FDA approves Gleevec as oral treatment for gastrointestinal stromal cancer
George Demetri, medical director of the Sarcoma Center at Dana-Farber Cancer Institute and associate professor of medicine at Harvard Medical School, was the lead investigator of a clinical study that looked at using Gleevec, an oral therapy, to treat occurrences of gastrointestinal stromal tumor.
FDA approves Gleevec as oral treatment for gastrointestinal stromal cancer
GIST, as it is known, is a rare form of sarcoma that typically originates in the stomach or intestinal tract.
http://www.researchmatters.harvard.edu/story.php?article_id=383   (253 words)

  
 The Turkish Journal of Gastroenterology
This association has often been detected incidentally on gastric mucosa or serosa, or occasionally intramurally, at surgery or gastroscopy for other reasons.
Diagnosis of gastrointestinal stromal tumors: a consensus approach.
Inflammatory reaction was found in some cases, as chronic atrophic gastritis or active chronic gastritis.
http://www.turkgastro.org/text.php?id=348   (1842 words)

  
 GIST Cancer Support Group - Life Raft Group
Since we received our non-profit status in June, 2002, we have expanded our outreach efforts to patients, and their doctors, throughout the world.
GIST Information.org Life Raft Group is a non-profit organization providing support, through information, education, and innovative research to patients with a rare cancer called GIST (Gastrointestinal Stromal Tumor).
http://www.liferaftgroup.org   (273 words)

  
 Quality Assurance
Immunohistochemical studies using CD117 (c-kit), S-100, actin and desmin may be necessary for better characterization of the tumour.
Immunohistochemical studies and EM examination may be considered to delineate its lineage.
Apart from the demonstraton of invasion of adjacent organs and metastatic spread, the most reliable guides to malignancy are site of tumour (most small intestinal tumours being malignant), size and mitotic count.
http://www.hkcpath.org/qap/viewanswer.asp?case=AP118   (365 words)

  
 ACTA Jul2002: Gastrointestinal Stromal Tumor in Ascitic Fluid: A Case Report
Distinguishing between the two neoplasms has important clinical repercussions and is aided by histochemical and immunocytochemical studies-in particular, c-kit immunostaining.
Background: There are few published data on the cytologic features of gastrointestinal stromal tumors (GISTs) in ascitic fluid and whether these features may mimic those of other malignancies.
Conclusion: GIST cells may closely mimic adenocarcinoma cells in ascitic fluid.
http://www.acta-cytol.com/Abs/ACTA1204.htm   (209 words)

  
 Clinical Trial: SU011248 in Treating Patients With Malignant Gastrointestinal Stromal Tumor
SU011248 in Treating Patients With Malignant Gastrointestinal Stromal Tumor
PURPOSE: Randomized phase III trial to study the effectiveness of SU011248 in treating patients who have malignant gastrointestinal stromal tumors that have not responded to imatinib mesylate.
Clinical Trial: SU011248 in Treating Patients With Malignant Gastrointestinal Stromal Tumor
http://clinicaltrials.gov/ct/gui/show/NCT00085618   (845 words)

  
 Boulder Community Network Health Center - Serving Boulder County since 1994
ClinicalTrials.gov A government site listing clinical trials and offering a guide to participating
Life Raft Group Provides support and information about trials for gastrointestinal stromal tumor (GIST), and the placebo issue
National Cancer Institute cancer.gov A government Web site offering a guide to cancer related trials
http://bcn.boulder.co.us/health/center.html   (1744 words)

  
 TargetTumors.org
Up until now, treatment options have been limited but there is hope in a drug called STI571 or Gleevec, which was recently approved for a common type of leukemia.
Gastrointestinal Stromal Tumors or GISTs are rare cancers that occur in the gastrointestinal tract.
Join Dr. George Demetri as he talks about GIST and the latest treatment strategies.
http://www.targettumors.org/tumors/gist.html   (57 words)

  
 EndoNurse - Epidemiology of Malignant Gastrointestinal Stromal Tumors
The epidemiology of gastrointestinal stromal tumor has not been well examined and prior studies often provide conflicting results.
Researchers conducted the first population-based study to evaluate the incidence and survival of malignant gastrointestinal stromal tumor in the United States.
The researchers utilized the Surveillance, Epidemiology and End Results registry from the National Cancer Institute to identify all cases of malignant gastrointestinal stromal tumor diagnosed from 1992 to 2000.
http://www.endonurse.com/hotnews/51h1785553.html   (374 words)

  
 Gi Stromal Tumor Prognosis And Ckit -
A list of medical terms, with definitions, that relate to carcinoid and related neuroendocrine tumors...
and is CKit positive, you may have been misdiagnosed as LMS, and really have a GIST [gastrointestinal stromal tumor...
Don't trust your health to the wrong surgeon.
http://tumor.fmqg.com/index.php?k=gi-stromal-tumor-prognosis-and-ckit   (183 words)

  
 MedlinePlus: Intestinal Cancer
What’s New in Gastrointestinal Stromal Tumor Research and Treatment?
Select services and providers for Intestinal Cancer in your area.
Incredible Journey through the Digestive System (Food and Drug Administration)
http://www.nlm.nih.gov/medlineplus/intestinalcancer.html   (165 words)

  
 Chemo - Gleevec Gleevec
Information about Gleevec Gleevec is used to treat Gleevec is used to treat certain types of cancer including Chronic Myeloid Leukemia (CML), and Gastrointestinal Stromal Tumors (GIST).
for: Gastrointestinal Diseases Stomach Diseases Neoplasms Resources from HONselect Double Dose of Gleevec Battles Intestinal Tumors More of drug could improve outcome for people with GIST, study finds
Cancer Issues-Double Dose of Gleevec Battles Intestinal Tumors
http://chemo-therapy-information.i56k.com/gleevec   (1211 words)

  
 University of Miami School of Medicine - Glossary - Gastrointestinal stromal tumor
Malignant GISTs can occur from the esophagus to the rectum, but occur most commonly in the stomach and small intestine.
University of Miami School of Medicine - Glossary - Gastrointestinal stromal tumor
A type of tumor that usually begins in cells in the wall of the gastrointestinal tract.
http://www.med.miami.edu/glossary/art.asp?articlekey=23038   (82 words)

  
 Gastrointestinal Carcinoid Tumor
Home > Conditions > G > Gastrointestinal Carcinoid Tumor
Conditions by letter: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
http://goldbamboo.com/topic-t3053.html   (101 words)

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