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| Â | British Journal of Pharmacology - Peripheral GABAB agonists stimulate gastric acid secretion in mice |
 | | Gastric acid secretory responses to SKF-97541 were increased when the somatostatin-dependent inhibitory mechanisms were blocked (immunoneutralization of the endogenous peptide and pharmacological blockade or genetic deletion of SSTR2 receptors) (Martinez et al., 1998; Piqueras et al., 2003b; 2004). | | | OHNING G.V., WONG H.C., LLOYD K.C. and WALSH J.H. (1996) Gastrin mediates the gastric mucosal proliferative response to feeding. | | | Moreover, in vitro studies in isolated rat gastric mucosa or in an isolated rat stomach preparation showed that GABA inhibited somatostatin release (Harty and Franklin, 1983; 1986; Koop and Arnold, 1986; Guo et al., 1989; Weigert, 1998), probably contributing to the acid secretory responses observed. |
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http://www.nature.com/bjp/journal/v142/n6/full/0705876a.html
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| Â | Stomach - Wikipedia, the free encyclopedia |
| | Gastric inhibitory peptide (GIP) and enteroglucagon decrease both gastric acid and motility. | | | Latin names for the stomach include Ventriculus and Gaster; many medical terms related to the stomach start in "gastro-" or "gastric". | | | The arteries supplying the stomach are the left gastric, the right gastric and right gastroepiploic branches of the hepatic, and the left gastroepiploic and short gastric branches of the lienal. |
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http://en.wikipedia.org/wiki/Stomach
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| Â | gastrin_releasing_peptide |
| | Erythropoietin (substance) Gastric inhibitory polypeptide (substance) Gastrin (substance) Gastrin-releasing peptide (substance) Gherlin (substance) Glucagon (substance) Glucagon-like peptide 1 (substance)... | | | Little (Little Gastrin) (Rat) 200ug 40.00        027-17 Gastrin Releasing Peptide-Ac (Ac-GRP) (20-27) (Porcine) 500ug 45.00        027-08 Gastrin... | | | Prev Term: gastrin inhibitor Next Term: gastrinoma syndrome gastrin releasing peptide See for: GRP Broader Terms: bombesin like peptide Scope Note: mammalian homolog of bombesin; widely distributed in GI... |
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http://gastrin_releasing_peptide.networklive.org
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| Â | The Stomach |
| | GIP (gastric inhibitory peptide) - glucose and fat stimulate release, inhibits gastric emptying and stimulates insulin secretion by pancreas, stimulates lipid storage in adipose and glucose use in skeletal muscle | | | Stretching - stimulates submucosal plexus causing release of gastric juice and myenteric plexus for peristalsis | | | Gastrin - release from G-cells stimulated by stretching or proteins acting as buffers and raising pH; causes gastric juice secretion, HCl secretion, strengthens stomach peristalsis, relaxes pyloric and ileocecal sphincters (gastroileal reflex); low pH inhibits gastrin release |
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http://www.mtsu.edu/~jshardo/bly2020/digestive/stomach.html
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| Â | Peptide - Multiple Peptide Systems |
| | Gastric inhibitory peptide (GIP) is a member of the secretin family of hormones. | | | The European Peptide Society was founded in 1989, primarily in order to ensure that Society members may subscribe to the Journal of Peptide Science at a | | | The compilation of papers dealing with solid phase peptide synthesis would be Luckily, Gregg Fields edited the book Solid Phase Peptide Synthesis in the |
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http://spiderarea.com/q/peptide.htm
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| Â | Secretin |
| | The sequence of the mature peptide is related to that of glucagon, vasoactive intestinal peptide and gastric inhibitory peptide. | | | Secretin is synthesized as a preprohormone, then proteolytically processed to yield a single 27-amino acid peptide by removal of the signal peptide plus amino and carboxy-terminal extensions. | | | Secretin is secreted in response to one known stimulus: acidification of the duodenum, which occurs most commonly when liquified ingesta from the stomach are released into the small intestine. |
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http://arbl.cvmbs.colostate.edu/hbooks/pathphys/endocrine/gi/secretin.html
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| Â | Gastrin ELISA > Assay Kit > Assay Designs |
| | < 0.001%: Gastrin Releasing Peptide (GRP)/ Gastrin Inhibitory Polypeptide (GIP)/ Glucagon/ Bombesin/ Pancreatic Polypeptide / Vasoactive Intestinal Peptide (VIP)/ Somatostatin-14 | | | Pyr-Arg-Pro-Pro-Met-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH Gastrins are a family of sequence-related carboxyamidated peptides produced by endocrine G cells of the antrum mucosa in response to a number of stimuli associated with digestion. | | | Gastrin is synthesized as a 101 residue pre-pro-peptide on the rough endoplasmic reticulum, then post-translationally modified by cleavage and alpha-amidation to result in the active forms G34, G17 and G13/14. |
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http://www.assaydesigns.com/products/catalog/immuno_assay/product_gastrin.htm
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| Â | Diabetes: Reduction of the incretin effect in rats by the... @ HighBeam Research |
| | The first incretin was isolated more than 20 years ago and was named gastric inhibitory polypeptide (GIP) on the basis of its first observed biological activity (6). | | | A wealth of recent data supports the new concept that the proglucagon-derived glucagon-like peptide 1 (GLP-1) is an important incretin factor (5)(11)(12)(13)(14)(15). | | | We have learned that peptides released after meals from the intestine are important mediators in the entero-insular axis and that intestino-pancreatic reflexes play only a minor role in this context (2). |
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http://www.highbeam.com/library/doc0.asp?DOCID=1G1:16285223&refid=holomed_1
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| Â | Indications - Short Bowel Syndrome |
| | Hormones that may be involved include secretin, serotonin, histaminase, cholecystokinin, pancreozymin, intestinal glucagon, vasoactive intestinal peptide, and gastric inhibitory peptide. | | | Surgical Considerations: The initial surgical approach to patients with extensive small bowel necrosis should be conservative, in an attempt to preserve as much intestine as possible. | | | Consent for surgical exploration should include a discussion with the patient and family of the potential need for home intravenous therapy. |
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http://surgery.mc.duke.edu/nutrition/secure/Short_bowel_syndrome.html
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| Â | Stomach - Open Encyclopedia |
| | Gastric inhibitory peptide (GIP) and enteroglucagon decrease both gastric acid and motility. | | | Similarly secretin, produced in the small intestine, has most effects on the pancreas, but will also diminish acid secretion in the stomach. | | | Other than gastrin, these hormones all act to turn off the stomach action. |
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http://open-encyclopedia.com/Stomach
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| Â | Nutrition Today: Nutrition and gastrointestinal function |
| | For example, protein is a potent stimulant of gastrin, cholecystokinin (CCK), and gastric inhibitory peptide (GIP) release; fat is a stimulant of CCK, secretin and GIP release as well as enteroglucagon, neurotensin, and peptide YY release; and carbohydrate is known to regulate release of GIP as well as the endocrine hormones, insulin and glucagon. | | | In reviewing this area three important themes, which will be illustrated further, are evident: 1) the importance of certain dietary components in stimulating the gastrointestinal response to food; 2) the adaptive response of the gastrointestinal tract to dietary factors; and 3) the physiology of the gastrointestinal tract has important consequences for the metabolism of nutrients. | | | The functions of these gut hormones and dietary stimulants of their release have recently been reviewed (Go, 1989). |
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http://www.findarticles.com/p/articles/mi_m0841/is_n1_v28/ai_13746460
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| Â | M MONTERO et al.: Evolution of the GHRH/PACAP precursors (Journal of Molecular Endocrinology) |
| | Moody AJ, Thim L and Valverde I 1984 The isolation and sequencing of human gastric inhibitory peptide (GIP). | | | Culler MD and Paschall CS 1991 Pituitary adenylate cyclase-activating polypeptide (PACAP) potentiates the gonadotropin-releasing activity of luteinizing hormone-releasing hormone. | | | Hart GR, Gowing H and Burrin JM 1992 Effects of a novel hypothalamic peptide, pituitary adenylate cyclase-activating polypeptide, on pituitary hormone release in male rats. |
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http://journals.endocrinology.org/jme/025/0157/jme0250157.htm
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| Â | Hydrochloric Acid |
| | HCl dumping into the small intestine stimulates the release of gastric inhibitory peptide (GIP), secretin and cholecystokinin (CCK) from the duodenal mucosa. | | | While the therapeutic efficacy of oral administration of HCl is still equivocal, largely due to a scarcity of outcome-focused clinical intervention studies, a substantial body of evidence indicates the necessity of proper gastric pH for optimal health. | | | Excessive amounts of gastrin have been associated with ulcer formation (Zollinger-Ellison syndrome). |
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http://www.thorne.com/altmedrev/fulltext/hcl.html
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| Â | Bad Godesberg on Encyclopedia.com |
| | Gastric inhibitory polypeptide and glucagon-like peptide-1 in the pathogenesis of type 2 diabetes.(Section V: the incretin pathway) | | | Bad Godesberg was incorporated into Bonn in 1969. | | | The German Social Democrats; a redefinition of social democracy or Bad Godesberg Mark II? |
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http://www.encyclopedia.com/html/B/BadG1odes.asp
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| Â | CONTROL OF GASTRIC EMPTYING |
| | increase release of CCK, gastric inhibitory peptide to increase pyloric tone | | | stimulates vagal cholinergic activity and release of secretin to increase sphincter tone | | | Sympathetic and vagal cholinergic stimulation constrict pyloric sphincter |
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http://medocs.ucdavis.edu/HPH/400/GIintro/tsld040.htm
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| Â | Health Quest |
| | cholecystokinin, motilin and gastric inhibitory peptide)” (Digestion ibid p.15). | | | Oral pancreatic enzymes increased efficiency in a subgroup of patients with impaired secretion ability (Digestion ibid p. |
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http://www.hquest.com/hq_handouts2.asp?VitaminName=Pancreatic%20Enzymes
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