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| | British Journal of Pharmacology - Peripheral GABAB agonists stimulate gastric acid secretion in mice |
 | | OHNING G.V., WONG H.C., LLOYD K.C. and WALSH J.H. (1996) Gastrin mediates the gastric mucosal proliferative response to feeding. | | | The role of vagal cholinergic pathways was determined by cholinergic blockade and vagotomy. | | | Moreover, in vitro studies in isolated rat gastric mucosa or in an isolated rat stomach preparation showed that GABA inhibited somatostatin release (Harty and Franklin, 1983; 1986; Koop and Arnold, 1986; Guo et al., 1989; Weigert, 1998), probably contributing to the acid secretory responses observed. |
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http://www.nature.com/bjp/journal/v142/n6/full/0705876a.html
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| | [No title] |
| | This condition is frequently associated with superficial gastric ulcer and discovered incidentally on biopsies of the ulcer edge and surrounding mucosa. | | | Recurrence: The 1-yr relapse rate for gastric and duodenal ulcers is > 60% after cessation of traditional antiulcer therapy. | | | Although it was originally surmised that long-term proton pump inhibitor therapy could predispose to the formation of stomach cancer, this does not appear to be the case. |
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http://sinoemedicalassociation.org/surgery/gastricsurgery/id19_m.htm
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| | Hydrochloric Acid |
| | While Allison did not claim the ten dermatology conditions were always due to B vitamin and HCl deficiency, his observations and therapeutic results suggest gastric acidity should be investigated in individuals presenting with these conditions. | | | Signs of oral mucosal inflammation improved in 78% of the patients, and of 22 patients with a complaint of a chronic sore mouth, 5 had complete relief and 11 others noted improvement. | | | General improvement in physical condition and strength was noted in all subjects. |
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http://www.thorne.com/altmedrev/fulltext/hcl.html
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| | CHECK YOUR STOMACH FOR SUFFICIENT HYDROCHLORIC ACID |
| | When the production of hydrochloric acid falls short, a fact easily demonstrable by laboratory techniques and which may be observed to take place at birth or at any time during our natural expanse of life, the conditions of hyper-chlorhydria, hypo- chlorhydria or achlorhydria take place. | | | Upon examination her temperature was found to be 100 degrees, respiration 56, pulse 160, she was highly toxic, cyanotic with a glassy glare in her eyes and she was unconscious. | | | It was on the strength of their efforts and the years of clinical work done by my mentor Dr. Black that I made this profound discovery. |
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http://www.rheumatic.org/hcl.htm
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| | The Medical Algorithms Project, Chapter10 |
| | Effect of Sham Feeding on Gastric Acid Secretion in Healthy Subjects and Duodenal Ulcer Patients: Evidence for Increased Basal Vagal Tone in Some Ulcer Patients. | | | The sham feeding test is used for confirmation of complete vagotomy. | | | • For two 15 minute collections (30 minutes) during the sham meal and for two 15 minute collections (30 minutes) after the sham meal collect gastric secretions and measure acid output (SAO). |
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http://www.medalreg.com/www/xdocs/docs_ch10/doc_ch10.01.html
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| | Gastric Acid Determination Principal Health News |
| | Most often cancerous, the tumor must be removed surgically; otherwise total surgical removal of the stomach is necessary. | | | If the patient has a sore throat, soothing lozenges may be given. | | | The gastric acid stimulation test is also not recommended in patients who are sensitive to pentagastrin (the drug used to stimulate gastric acid output). |
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http://www.principalhealthnews.com/topic/topic100586860
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| | Gastric Acid Secretion, Blood Flow, and Mucosal Barrier Function |
| | In addition, chronic intravenous and intestinal cannulas can be implanted in these animals for the assessment of exogenously administered substances. | | | This model has the advantage of providing a consistently low basal secretory rate and reliable assessment of responses to exogenous stimulants of gastric acid secretion given either peripherally (intravenously, intra-arterially, intraperitoneally) or centrally (intracerebroventricularly, intracisternally or microinjection into the brain parenchyma), and to endogenous stimulants, such as an intragastric meal. | | | The anesthetized mouse model enables the study of gastric secretory physiology which previously has only been studied in an ex vivo preparation. |
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http://www.cure.med.ucla.edu/facilities/facilities_animala.html
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| | MedlinePlus Medical Encyclopedia: Gastric ulcer |
| | Calling your health care provider Return to top | | | Surgical intervention may be recommended for people who do not respond to medical therapy or to endoscopic therapy for bleeding. | | | Call your health care provider if symptoms of gastric ulcer develop. |
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http://www.nlm.nih.gov/medlineplus/ency/article/000213.htm
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| | The Parietal Cell: Mechanism of Acid Secretion |
| | As a consequence, the parietal cell and the mechanisms it uses to secrete acid have been studied extensively, leading to development of several drugs useful for suppressing acid secretion. | | | Even though many of the actors are unlabeled, you should be able to deduce the identity of all the components you see. | | | Drug Therapy for Suppressing Secretion of Gastric Acid |
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http://arbl.cvmbs.colostate.edu/hbooks/pathphys/digestion/stomach/parietal.html
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| | Gastric Acid Secretion |
| | gastric distention activates reflex arc in vagus, releasing acetylcholine | | | inhibition of enzymes involved in prostaglandin production(cyclo-oxygenases =COX) by NSAIDs (non-steroidal anti-inflammatory drugs) such as aspirin, ibuprofen, etc. results in gastric damage | | | fatty acids, peptides stimulate release of GIP (gastric inhibitory polypeptide) and CCK (cholecystokinin) |
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http://meds.queensu.ca/medicine/physiol/undergrad/phase2/phase2e/Ph2acid.htm
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| | Clinical Trial: Esomeprazole In Patients With Gastric Acid Hypersecretory States Including Idiopathic Hypersecretion ... |
| | Esomeprazole In Patients With Gastric Acid Hypersecretory States Including Idiopathic Hypersecretion and Zollinger-Ellison Syndrome | | | Primary Outcomes: To assess the gastric acid secretory rate at the final study visit.; Control is defined as gastric acid secretory rate below 10 mEq/h or below 5 meq/h for patients with prior gastric acid reducing Surgery | | | Clinical Trial: Esomeprazole In Patients With Gastric Acid Hypersecretory States Including Idiopathic Hypersecretion and Zollinger-Ellison Syndrome |
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http://clinicaltrials.gov/ct/gui/show/NCT00079833
(242 words)
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| | Gastric Secretions |
| | Once secreted, pepsinogen is activated by stomach acid into the active protease pepsin, which is largely responsible for the stomach's ability to initiate digestion of proteins. | | | The stomach is famous for its secretion of acid, but acid is only one of four major secretory products of the gastric epithelium, all of which are important either to the digestive process or to control of gastric function: | | | This acid is important for activation of pepsinogen and inactivation of ingested microorganisms such as bacteria. |
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http://arbl.cvmbs.colostate.edu/hbooks/pathphys/digestion/stomach/secretion.html
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