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Topic: Fibroblast



  
 Growth and Cell Cycle Abnormalities of Fibroblasts From Tangier Disease Patients -- Drobnik et al. 19 (1): 28 -- ...
Results represent mean±SEM of 4 and 3 experiments, each performed in triplicate, on fibroblasts from 4 normal subjects and 3 TD patients, respectively.
Each bar represents mean±SEM of 2 experiments performed in duplicate on fibroblasts from 2 control subjects and 2 TD patients, respectively.
Each bar represents mean±SEM of 4 and 2 experiments, performed in duplicate, on fibroblasts from 4 control subjects and 2 TD patients, respectively.
http://atvb.ahajournals.org/cgi/content/full/19/1/28   (5915 words)

  
 High Efficiency Myogenic Conversion of Human Fibroblasts by Adenoviral Vector-mediated MyoD Gene Transfer . An ...
The rationale of this approach is that fibroblasts are not affected
Fibroblasts isolated from human fetal skin were expanded and transduced in vitro with a high-titer stock of the retroviral
fibroblasts from skin, muscle, or bone marrow were infected by
http://www.jci.org/cgi/content/full/101/10/2119   (6115 words)

  
 Defect of Hepatocyte Growth Factor Secretion by Fibroblasts in Idiopathic Pulmonary Fibrosis -- Marchand-Adam et al. ...
Representative Western blot analysis of HGF in fibroblast supernatants taken from one patient with IPF and one control patient and cultured under basal conditions.
Fibroblast supernatants and recombinant human HGF (rh-HGF, a
by pulmonary fibroblasts isolated from fibrotic lungs was specifically
http://ajrccm.atsjournals.org/cgi/content/full/168/10/1156   (3780 words)

  
 Keratinocyte Growth Factor Produced by Gastric Fibroblasts Specifically Stimulates Proliferation of Cancer Cells from ...
by human gastric fibroblasts stimulated proliferation of human
KGF mRNA was expressed in gastric fibroblasts, esophageal fibroblasts,
mRNA was expressed in gastric fibroblasts but not in gastric
http://cancerres.aacrjournals.org/cgi/content/full/63/24/8848   (3077 words)

  
 Increased Plasminogen Activator Inhibitor-1 in Keloid Fibroblasts May Account for their Elevated Collagen Accumulation ...
Early passages (2 to 10) of fibroblasts were used in the experiments.
Fibroblasts in fibrin matrix actively reorganize the matrix
level, skin fibroblasts were isolated from normal skin, normal
http://ajp.amjpathol.org/cgi/content/full/162/5/1579   (6404 words)

  
 Leukoregulin induction of protein expression in human orbital fibroblasts: Evidence for anatomical site-restricted ...
fibroblasts from the orbit and those in pretibial skin.
Orbital fibroblast strains were initiated from tissue explants of surgical waste at the time of transantral decompressive
In these experiments, involving orbital and dermal fibroblasts,
http://www.pnas.org/cgi/content/full/95/15/8904   (3806 words)

  
 Nicotinamide Decreases Cytokine-Induced Activation of Orbital Fibroblasts from Patients with Thyroid-Associated ...
to the orbital fibroblasts, we repeated the experiments, using skin
human orbital fibroblasts derived from surgical specimens from
on skin fibroblasts by nicotinamide was noted (Fig.
http://jcem.endojournals.org/cgi/content/full/83/1/121   (2169 words)

  
 Mesenchymal-epithelial interactions in the skin: increased expression of dickkopf1 by palmoplantar fibroblasts inhibits ...
This experiment was performed four times with melanocytes and fibroblasts derived from different individuals with similar results.
Regulation of keratin 9 in nonpalmoplantar keratinocytes by palmoplantar fibroblasts through epithelial-mesenchymal interactions.
interactions by fibroblasts derived from palmoplantar and nonpalmoplantar
http://www.jcb.org/cgi/content/full/165/2/275   (6015 words)

  
 Nerve growth factor displays stimulatory effects on human skin and lung fibroblasts, demonstrating a direct role for ...
To further explore the activity of NGF on fibroblast migration, NGF was added to skin and lung fibroblast wounded monolayers.
In contrast, culture of both lung and skin fibroblasts with NGF
Addition of 200 ng/ml NGF to both lung and skin fibroblasts
http://www.pnas.org/cgi/content/full/98/11/6162   (4092 words)

  
 GH and Epidermal Growth Factor Signaling in Normal and Laron Syndrome Fibroblasts -- Silva et al. 143 (7): 2610 -- ...
MAPK in the LS fibroblasts, demonstrating a defect in this pathway
In experiments to determine the role of PI3K, fibroblasts were
Lysates were analyzed by Western blotting with an anti-p70
http://endo.endojournals.org/cgi/content/full/143/7/2610   (5355 words)

  
 Synovial Fibroblasts Infected with Salmonella enterica Serovar Typhimurium Mediate Osteoclast Differentiation and ...
Infected synovial fibroblasts stimulate osteoclastogenesis and bone resorption.
expressed by synovial fibroblasts and was not upregulated by
(RA) (7, 18), suggesting that synovial fibroblasts could contribute
http://iai.asm.org/cgi/content/full/72/12/7183   (2768 words)

  
 Fibroblasts - definition of Fibroblasts in Encyclopedia
Active fibroblasts can be recognized by their abundant rough endoplasmic reticulum.
Tissue damage stimulates fibrocytes and induces the mitosis of fibroblasts.
Fibroblasts make collagens, glycosaminoglycans, reticular and elastic fibers, and glycoproteins found in the extracellular matrix.
http://encyclopedia.laborlawtalk.com/Fibroblasts   (144 words)

  
 Box 1 Stromal fibroblasts in cancer initiation and progression : Nature
The origin of the mesenchymal fibroblasts apparently determines their sensitivity to sonic hedgehog (Shh) derived from the developing lung epithelia.
Other epithelia may show no such response, for example, oesophagus epithelia showed no hyperplastic or neoplastic response in the Tgfbr2
In a reductionist approach to understanding epithelial−stromal interactions, both in normal tissues and in cancer, the fibroblast component is often generalized and differences in fibroblasts from different tissues or differences within the same tissue are obscured.
http://www.nature.com/nature/journal/v432/n7015/box/nature03096_bx1.html   (346 words)

  
 Systemic Sclerosis (Scleroderma): Specific Autoantigen Genes Are Selectively Overexpressed in Scleroderma Fibroblasts ...
Autoantibodies to Fibrillin-1 Activate Normal Human Fibroblasts in Culture through the TGF-{beta} Pathway to Recapitulate the "Scleroderma Phenotype"
of dermal fibroblasts from patients with eosinophilic fasciitis
and its tissue specificity for fibroblasts, cDNA microarrays
http://www.jimmunol.org/cgi/content/abstract/167/12/7126   (718 words)

  
 Deficient Regulation of DNA Double-strand Break Repair in Fanconi Anemia Fibroblasts -- Donahue et al. 278 (32): 29487 ...
HR was assayed in human diploid fibroblasts by electroporating
fibroblasts from FA patients and from normal subjects.
are human diploid FA fibroblasts from patients of complementation
http://www.jbc.org/cgi/content/full/278/32/29487   (6668 words)

  
 The role of fluoride ions in glycosaminoglycans sulphation in cultured fibroblasts
The results of this study concerning the effect of trace amounts of F
Fibroblasts were cultured with the addition of NaF ([F
Fibroblast cultures were used in the study to evaluate F
http://www.fluoride-journal.com/98-31-4/314-193.htm   (3153 words)

  
 Proliferative Activity of Intratumoral Fibroblasts Is Closely Correlated with Lymph Node and Distant Organ Metastases ...
There was no significant correlation in mean MIB-1 LI of fibroblasts
Immunohistochemistry for MIB-1 of fibroblasts in the inner area within IDC.
in IDCs, and expression of some oncogene in fibroblasts may
http://ajp.amjpathol.org/cgi/content/full/156/5/1701   (4916 words)

  
 Cascade Biologics: Human Dermal Fibroblasts, adult
Normal human dermal fibroblasts isolated from adult skin, cryopreserved at the end of the primary culture.
Secondary cultures established from cryopreserved normal human dermal fibroblasts, grown to approximately 50% confluence in T-flasks.
Human Dermal Fibroblasts, adult (HDFa), proliferating culture in 6xT25 Flasks
http://www.cascadebio.com/index.cfm?fuseaction=home.Content&CID=433   (133 words)

  
 Liver Facts
"But what if we could trick the body into a wound-healing response that's in a very confined environment, where cells like fibroblasts couldn't come in?" Shastri wondered.
Even better, fibroblasts are relegated to the outer side of the periosteum -- effectively barring them from participating in the process.
But there's one roadblock: natural wound healing usually involves fast-growing cells called fibroblasts that give rise to scar tissue.
http://www.liverfacts.com/ms/news/527056/main.html   (1185 words)

  
 NDI Terminology - fibroblasts
Fibroblasts, which differentiate into chondroblasts, collagenoblasts, and osteoblasts, form the fibrous tissues in the body including tendons, aponeuroses, supporting and binding tissues of all sorts.
Connective tissue cells: flat elongated cells with cytoplasmic processes at each end, having flat, oval, vesicular nuclei.
http://www.ndif.org/Terms/fibroblasts.html   (42 words)

  
 MMP-2 release and activation in ovarian carcinoma: the role of fibroblasts
The matrix metalloproteinase MMP-2 is up-regulated in epithelial cancers and its mRNA localizes to stromal fibroblasts.
This active MMP-2 can associate with the cell surface of tumour cells and fibroblasts and is used in the processes of tissue remodelling and invasion.
We propose that, in the ovarian tumour microenvironment, interaction between tumour cells and fibroblasts may enhance fibroblast production of the proMMP-2 and TIMP-2.
http://www.nature.com/cgi-taf/DynaPage.taf?file=/bjc/journal/v80/n3/abs/6690357a.html   (212 words)

  
 vitamin - Columbia Encyclopedia® article about vitamin
Cells called fibroblasts form the various fibers in connective tissue in the body.
http://columbia.thefreedictionary.com/vitamin   (3868 words)

  
 Injured Corneal Epithelial Cells Promote Myodifferentiation of Corneal Fibroblasts -- Nakamura et al. 43 (8): 2603 -- ...
myodifferentiation of fibroblasts may not contribute to collagen
positive feedback from fibroblasts to epithelial cells, or participation
To our knowledge, this is the first in vitro study of the influence
http://www.iovs.org/cgi/content/full/43/8/2603   (3082 words)

  
 Normal Human Fibroblasts Are Resistant to RAS-Induced Senescence -- Benanti and Galloway 24 (7): 2842 -- Molecular and ...
Normal Human Fibroblasts Are Resistant to RAS-Induced Senescence
Normal Human Fibroblasts Are Resistant to RAS-Induced Senescence -- Benanti and Galloway 24 (7): 2842 -- Molecular and Cellular Biology
We show here that in contrast to cultured fibroblast
http://mcb.asm.org/cgi/content/abstract/24/7/2842   (307 words)

  
 MedlinePlus Medical Encyclopedia: Familial hypercholesterolemia
special studies of patient cells (fibroblasts) may show decreased uptake of LDL cholesterol
http://www.nlm.nih.gov/medlineplus/ency/article/000392.htm   (814 words)

  
 Lysosomal Cystine Storage Augments Apoptosis in Cultured Human Fibroblasts and Renal Tubular Epithelial Cells -- Park ...
versus 5.2% and 7.1% in normal fibroblasts when analyzed by
Lysosomal Cystine Storage Augments Apoptosis in Cultured Human Fibroblasts and Renal Tubular Epithelial Cells
Lysosomal Cystine Storage Augments Apoptosis in Cultured Human Fibroblasts and Renal Tubular Epithelial Cells -- Park et al.
http://jasn.asnjournals.org/cgi/content/abstract/13/12/2878   (407 words)

  
 Induction of apoptosis in human replicative senescent fibroblasts.
Induction of apoptosis in human replicative senescent fibroblasts.
Our studies show that senescent fibroblasts can be induced to undergo apoptosis in a signal-dependent manner.
Using an in situ assay, we have found that the activity of beta-galactosidase, which is also a biochemical marker of senescence, is induced in young proliferating fibroblasts following exposure to all three apoptotic inducing agents.
http://www.arclab.org/medlineupdates/abstract_11855860.html   (242 words)

  
 Holistic Health Encyclopedia - D
The dermis contains mostly fibroblasts which are responsible for secreting collagen, elastin and ground substance that give the support and elasticity of the skin.
The dermis is typically subdivided into two zones, a papillary dermis and a reticular layer.
http://www.findhealer.com/glossary/D.php3   (5492 words)

  
 Collagen - Wikipedia, the free encyclopedia
It is found in tendons and the organic part of bone.
Type V collagen - most interstitial tissue, assoc.
Type III collagen - This is the collagen of granulation tissue, and is produced quickly by young fibroblasts before the tougher type I collagen is synthesised.
http://en.wikipedia.org/wiki/Collagen   (544 words)

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