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| | American Family Physician: Fibrinolysis or angioplasty in acute myocardial infarction - Tips from Other Journals |
 | | All patients received aspirin, intravenous beta-blocker therapy, and heparin. | | | The incidence of disabling stroke was low and similar between the angioplasty and fibrinolysis groups (1.6 and 2.0 percent, respectively). | | | The editorial author advocates transfer for angioplasty whenever the expected transfer delay will be less than one hour, if infarction symptoms have been present for more than three hours (i.e., fibrinolysis is less effective), or when fibrinolytic therapy is contraindicated or not successful. |
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http://www.findarticles.com/p/articles/mi_m3225/is_6_69/ai_114608444
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| | ECP |
| | Decision analysis is an explicit, quantitative approach to weighing the risks and benefits of fibrinolysis in different subgroups of patients with acute myocardial infarction. | | | Given the numerous variables involved in clinical decision making, identifying which patients are likely to benefit most from fibrinolysis is not straightforward; this may, in part, explain poorer outcomes observed in community-based settings compared with those reported in large clinical trials. | | | Such printouts—which show the estimated chances with and without fibrinolysis for acute myocardial infarction, death within 30 days from myocardial infarction, and stroke—typically were reviewed immediately by the physician on duty, who would then determine how best to manage the patient. |
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http://www.acponline.org/journals/ecp/janfeb01/kellett.htm?hp
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| | Acute Myocardial Infarction and Coronary Syndromes: Optimizing Selection of Reperfusion and Revascularization Therapies ... |
| | Overall, the preliminary results of ENTIRE suggest that, regardless of whether full-dose fibrinolysis with tenecteplase or combination therapy is employed for facilitated reperfusion in the setting of cardiac catheterization and/or PCI, the anticoagulant enoxaparin is at least as effective and safe as UFH in all patient subsets. | | | The requirement of administering prompt reperfusion therapy to these patients, as well as the other limitations of fibrinolytic therapy, have led many clinicians to advocate PCI as the primary therapy and treatment of choice for AMI. | | | Identifying those patients who represent ideal candidates for fibrinolysis, and who are likely to have outcomes at least as favorable as they would with percutaneous interventions, has become an area of intense focus among cardiologists and emergency physicians. |
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http://www.ahcpub.com/acutemi.html
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| | eMedicine - Thrombolytic Therapy : Article by Craig Feied, MD, FACEP, FAAEM, FACPh |
| | In patients receiving fibrinolysis for acute stroke, the incidence of intracranial hemorrhage is higher. | | | In patients receiving fibrinolysis for MI, the overall incidence of hemorrhagic complications is about 10%, and the incidence of intracranial hemorrhage is about 0.7%. | | | In patients receiving fibrinolysis for acute stroke, any sign of a major infarct increases the likelihood of hemorrhagic conversion. |
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http://www.emedicine.com/emerg/topic831.htm
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| | News - Little Difference Between Prehospital Fibrinolysis Or Emergency Angioplasty For MI |
| | Rescue angioplasty was done in 26 percent of the patients in the fibrinolysis group. | | | Although prehospital fibrinolysis and primary angioplasty provide a clinical benefit over in-hospital fibrinolysis, these two strategies for the treatment of severe MI have not been directly compared, points out Dr. Eric Bonnefoy and colleagues from University Hospital, Lyon, France. | | | At the same time, the clinicians said they found trends suggesting increased risk of MI recurrence and stroke among patients given fibrinolytic therapy. |
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http://docguide.com/news/content.nsf/news/8525697700573E1885256C32002F553B
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| | TIGC - TThrombolytic - Arterial |
| | Local fibrinolysis is a useful adjunct technique during surgery when there are residual thrombi or new thrombi arising from a complicated procedure. | | | Although fibrinolysis sometimes results in less extensive surgical interventions (STILE and TOPAS studies, both randomized), major end points such as mortality and amputation-free survival are not significantly different. | | | Despite this, the role of thrombolytic therapy is still controversial and requires considerable clinical expertise with a team approach usually consisting of an interventional radiologist, a vascular surgeon and/or an internist. |
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http://www.tigc.org/eguidelines/thromlyticarterial04.htm
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| | eMedicine - Alpha2-Plasmin Inhibitor Deficiency : Article by Rajalaxmi McKenna, MD, FACP |
| | PI levels was believed to be secondary to clot formation in the chest; irrigation and removal of the clots along with the use of inhibitors of fibrinolysis help reduce excess local fibrinolytic activity in the chest cavity. | | | PI plays a key role in the physiologic control of fibrinolysis by helping localize reactions to the sites where they are needed and by helping prevent systemic spillover. | | | The increase in serious thrombotic complications, such as acute myocardial infarction and stroke, which was anticipated with wider use of antifibrinolytic drugs, has not materialized. |
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http://www.emedicine.com/med/topic109.htm
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| | Blood Coagulation and Fibrinolysis |
| | Blood Coagulation and Fibrinolysis is an international fully-refereed Journal that features review and original research articles on all clinical, laboratory and experimental aspects of haemostasis and thrombosis. | | | The Journal is devoted to publishing significant developments worldwide in the field of blood coagulation, fibrinolysis, thrombosis, platelets and the kininogen-kinin system, as well as dealing with those aspects of blood rheology relevant to haemostasis and the effects of drugs on haemostatic components. | | | Involvement of TNFandalpha; Case Report: Novastan® anticoagulation during renal stent implant in a patient with heparin-induced thrombocytopenia Contact: Managing Editor, Katy Christomanou, katy.christomanou@rapidcom.co.uk |
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http://gort.ucsd.edu/newjour/b/msg02348.html
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| | Blood Coagulation and Fibrinolysis |
| | Blood Coagulation and Fibrinolysis is undoubtedly one of the major journals in haemostasis and thrombosis research today. | | | The scope of the journal includes blood coagulation, platelets, fibrinolysis, hemophilia, arteri...more. | | | Blood Coagulation and Fibrinolysis An International Journal in Haemostasis and Thrombosis |
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http://www.lww.com/product?0957-5235
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| | Bylaws of the International Society for Fibrinolysis and Proteolysis |
| | Specifically, the objectives include the furtherance of scientific research relating to fundamental and medical aspects of Fibrinolysis, Proteolysis and Thrombolysis, the futherance of resarch in related disciplines, the interchange of ideas through the organization of scientific conferences (cf. | | | http://www.fibrinolysis.org), and the stimulation of scientific activities for the developments in Fibrinolysis, Proteolysis and Thrombolysis (cf. | | | The objectives of the Society, which has no profit motive, are exclusively scientific and educational in nature. |
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http://www.fibrinolysis.org/pages/Bylaws_of_ISFP.htm
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| | Blood Coagulation & Fibrinolysis |
| | Blood Coagulation and Fibrinolysis is unquestionably one of the major journals in hemostasis and thrombosis research. | | | This journal's broad scope encompasses many key research topics, including blood coagulation, platelets, fibrinolysis, hemophilia, arterial disease, and drug effects. | | | To meet the demands for timely research in this dynamic field, the editorial board of Blood Coagulation and Fibrinolysis offers a rapid review of submitted papers, and all papers are published within eight weeks of acceptance. |
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http://www.ovid.com/site/catalog/Journal/435.jsp?top=2&mid=3&bottom=7&subsection=12
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| | Recent Progress in Blood Coagulation and Fibrinolysis - SHOP.COM |
| | This book documents the proceedings and is beneficial to those wishing to update their information on this very important clinical area. | | | Great progress has been made recently in basic and clinical research aspects of thrombosis and fibrinolysis. | | | This progress has implications not only in haemorrhagic and thrombotic conditions, but also in such widely diverse clinical conditions as atherosclerosis, diabetes, obesity, tumor growth/metastasis, pregnancy etc. Procedures employed in this research include not only new biochemical approaches but also novel procedures in molecular biology which involve gene neutralisation, manipulation and transfection. |
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http://www.shop.com/amos/cc/main/searchxs1/ccsyn/260/prd/20748516
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| | Immunochemicals for Rat Fibrinolysis - Aniara |
| | These Immunochemicals Rat Fibrinolysis are particularly useful for any study on fibrinolysis designed with the rat model, and mainly for protocols on fibrinolytic mechanisms and metabolism studies. | | | Mab specific for rat PAI-1 peroxidase conjugate (clone 2) |
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http://aniara.com/rat-immunoeu.htm
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| | AtheroNews - 18 September 2002 - No advantage of primary angioplasty over prehospital fibrinolysis in acute MI |
| | No advantage of primary angioplasty over prehospital fibrinolysis in acute MI For patients with acute MI, primary angioplasty proved no better than prehospital fibrinolysis followed by transfer for possible emergency coronary angioplasty. | | | The rate of the primary composite endpoint of death, non-fatal reinfarction, and non-fatal disabling stroke at 30 days was 8.2% (34 patients) in the prehospital-fibrinolysis group and 6.2% (26 patients) in the primary-angioplasty group. | | | Primary angioplasty versus prehospital fibrinolysis in acute myocardial infarction: a randomized study. |
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http://www.atherothrombosis.org/news/200209/nh_sep18a.cfm
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| | fibrinolysis |
| | Primary fibrinolysis refers to the normal breakdown of clots, whereas secondary fibrinolysis is the breakdown of blood clots and possible abnormal bleeding... | | | PTA/Stenting Improves Clinical Outcome in Acute Vertebrobasilar Occlusion: Combined Local Fibrinolysis and Intravenous Abciximab in Acute Vertebrobasilar Stroke Treatment (FAST): Results of a... | | | For the pre-hospital reperfusion research group Edmonton (PURGE). |
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http://fibrinolysis.networklive.org
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| | PRIMARY ANGIOPLASTY VS. FIBRINOLYSIS IN ACUTE MYOCARDIAL INFARCTION: ASSESSING LONG-TERM COST EFFECTIVENESS ... |
| | Probabilistic sensitivity analysis suggested that in nearly 80% of sample clinical trials, primary angioplasty was economically dominant over fibrinolysis. | | | The purpose of this study was to assess the long-term incremental cost effectiveness of primary angioplasty compared with fibrinolysis and to assess the overall certainty of the baseline analysis using probabilistic sensitivity analysis. | | | Cumulative reinfarctions would be 11.5% in the primary angioplasty arm and 20.3% in the fibrinolysis arm. |
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http://www.pulsus.com/ccc2003/abs/a809.htm
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| | Blood Coagulation & Fibrinolysis - |
| | Whether you're seeking a healthcare job, or looking for an experienced healthcare professional to fill an opening, the Job Center can make your search faster, easier, and more effective. | | | I would like to receive info from Blood Coagulation & Fibrinolysis | | | You may share my information with select Blood Coagulation & Fibrinolysis partners: |
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http://mbc.medcareers.com/signup
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| | Disease - Primary or secondary fibrinolysis - Hartford, Connecticut |
| | Primary fibrinolysis refers to the normal breakdown of clots, whereas secondary fibrinolysis is the breakdown of blood clots and possible abnormal bleeding due to another medical disorder, medications, or other causes. | | | Fibrinolysis leads to the breakdown of fibrin clots ( blood clots) and is caused by the action of several enzymes. | | | However, fibrinolysis can increase under certain conditions (such as intense exercise, inadequate oxygenation of tissues, low blood sugar, or bacterial infections). |
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http://www.saintfranciscare.com/13466.cfm
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| | Fibrinolysis - Wikipedia, the free encyclopedia |
| | Fibrinolytic drugs are given after a heart attack to dissolve the thrombus blocking the coronary artery, experimentally in stroke to reperfuse the affected part of the brain, and in massive pulmonary embolism. | | | Plasmin activity is also reduced by thrombin-activatable fibrinolysis inhibitor (TAFI), which modifies fibrin to make it less susceptible to plasmin cleavage. | | | This effect can be seen in the thrombin clotting time (TCT) test, which is prolonged in a person who has active fibrinolysis. |
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http://en.wikipedia.org/wiki/Fibrinolysis
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| | Identification of thrombin activatable fibrinolysis inhibitor (TAFI) in human platelets -- Mosnier et al. 101 (12): ... |
| | Identification of thrombin activatable fibrinolysis inhibitor (TAFI) in human platelets | | | From the Thrombosis and Haemostasis Laboratory, Department of Haematology, University Medical Center Utrecht; Institute of Biomembranes, Utrecht University; and Department of Vascular Medicine, Academic Medical Center, University of Amsterdam, The Netherlands. | | | Risk of Ischemic Stroke Associated With Functional Thrombin-Activatable Fibrinolysis Inhibitor Plasma Levels |
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http://www.bloodjournal.org/cgi/content/abstract/101/12/4844
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| | Synonyms of fibrinolysis |
| | usage: a normal ongoing process that dissolves fibrin and results in the removal of small blood clots; "drugs causing fibrinolysis have been utilized therapeutically" |
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http://www.infoplease.com/thesaurus/fibrinolysis
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| | XVIIth International Congress on Fibrinolysis and Proteolysis (ISFP), Melbourne, Australia |
| | This congress will provide a forum for those who work in the area of Fibrinolysis and Proteolysis to showcase their work, exchange ideas and communicate current developments and advancements. | | | The congress will contain Plenary Lectures, State of the Art Lectures and Symposia that will address both basic and clinical aspects of Fibrinolysis and Proteolysis in the contexts of cardiovascular disease (including diabetes and obesity), thrombolysis, vascular biology, cell adhesion, angiogenesis, cancer metastasis, gene regulation and neurobiology. | | | This year, we have invited our colleagues from the Asia-Pacific Society on Thrombosis and Haemostasis (APCTH) to participate in the ISFP2004 Congress and we are pleased to announce that a special session has been devoted for this purpose. |
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http://www.icms.com.au/isfp2004
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| | Identification of the epidermal growth factor-like domains of thrombomodulin essential for the acceleration of ... |
| | Braat, E.A.M., Jie, A.F.H., Ronday, H.K., Beekman, B. and Rijken, D.C. (2000) Urokinase mediated fibrinolysis in the synovial fluid of rheumatoid arthritis patients may be affected by the inactivation of single chain urokinase type plasminogen activator by thrombin. | | | Emeis, J.J., Verheijen, J.H., Ronday, H.K., De Maat, M.P.M. and Brakman, P. (1997) Progress in clinical fibrinolysis. | | | (tcu-PA), which plays a role in fibrinolysis and extracellular |
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http://www.ejbiochem.org/cgi/content/full/268/21/5562
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