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Topic: Fibrinogen



  
 Fibrinogen test
Other conditions related to decreased fibrinogen levels are those in which fibrinogen is completely absent (congenital afibrinogenemia), conditions in which levels are low (hypofibrinogenemia), and conditions of abnormal fibrinogen (dysfibrinogenemia).
Fibrinogen plays two essential roles in the body: it is a protein called an acute-phase reactant that becomes elevated with tissue inflammation or tissue destruction, and it is also a vital part of the "common pathway" of the coagulation process.
This test is not recommended for patients with active bleeding, acute infection or illness, or in those patients who have received blood transfusions within four weeks.
http://www.healthatoz.com/healthatoz/Atoz/ency/fibrinogen_test.jsp   (817 words)

  
 fibrinogen - definition of fibrinogen in Encyclopedia
Fibrinogen is a 340-KD glycoprotein synthesised in the liver hepatocytes and megakaryocytes, which normally has a concentration between 1.5 - 4.0 g/L (normally measured using the Clauss method) in blood plasma.
Processes in the coagulation cascade activate the zymogen prothrombin to the serine protease thrombin, which is responsible for converting fibrinogen into fibrin.
Fibrin is then cross linked by factor XIII to form a clot.
http://encyclopedia.laborlawtalk.com/fibrinogen   (365 words)

  
 Coagulation - Wikipedia, the free encyclopedia
This is reported as an INR value when used for the dosing of oral anticoagulants such as warfarin.
If a coagulation factor is part of the contact or tissue factor pathway, a deficiency of that factor will affect only one of the tests: thus hemophilia A, a deficiency of factor VIII, which is part of the contact factor pathway, results in an abnormally prolonged aPTT test but a normal PT test.
Measurement of the exact amount of fibrinogen present in the blood is generally done using the Clauss method for fibrinogen testing.
http://en.wikipedia.org/wiki/Blood_clotting   (2222 words)

  
 MedlinePlus Medical Encyclopedia: Fibrinogen
Additional conditions under which the test may be performed:
This is a test that measures the amount of fibrinogen in the blood.
This test may be performed when abnormal blood clotting is present, particularly if there is excessive bleeding.
http://www.nlm.nih.gov/medlineplus/ency/article/003650.htm   (659 words)

  
 Holistic Health Encyclopedia - P
Plasma is to be distinguished from serum, which is the cell-free portion of the blood from which the fibrinogen has been separated in the process of clotting.
http://www.findhealer.com/glossary/P.php3   (9218 words)

  
 Heart and Stroke Encyclopedia
Fibrinogen — see Estrogen and Cardiovascular Diseases in Women
http://www.americanheart.org/presenter.jhtml?identifier=10000056   (5617 words)

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