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| | Functional MR Imaging of the Brain (fMRI) |
 | | fMRI not only helps radiologists look closely at the anatomy of the brain, but can help them determine precisely which part of the brain is handling critical functions such as thought, speech, movement and sensation. | | | This information can be critical to planning surgery, radiation therapy, treatment for stroke or other interventions to treat brain disorders. | | | Functional magnetic resonance imaging (fMRI) is a relatively new procedure that uses MR imaging to measure the quick, tiny metabolic changes that take place in an active part of the brain. |
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http://www.radiologyinfo.org/content/functional_mr.htm
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| | fMRI - About Functional MRI(General) |
| | The goal of this presentation was to introduce the basics of fMRI and to suggest potential future applications in neuro-oncology. | | | Based on our initial investigations, these future directions include neurosurgical planning and improved assessment of risk for individual patients, improved assessment and strategies for the treatment of chronic pain, improved seizure localization, and improved understanding of the physiology of neurological disorders. | | | These preliminary studies suggest a wide range of other approaches using fMRI to investigate cortical representations of specific pain types, and therefore, new specific therapy options. |
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http://www.fmri.org/fmri.htm
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| | Neuroguide.com - Functional Magnetic Resonance Imaging |
| | The principle of fMRI imaging is to take a series of images of the brain in quick succession and to statistically analyze the images for differences among them. | | | This method can also be used to study the physiology of other organs-- for example, studying blood flow to pathological organs, thus helping us to understand the disease process. | | | The same group later used gradient echo and spin-echo inversion recovery fMRI to examine blood oxygenation levels and blood flow rates, respectively, in brain (Kwong, et al., 1992). |
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http://www.neuroguide.com/gregg.html
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| | HNL - Human Neuroimaging Lab |
| | In principle, fMRI can be used to observe the activation of brain structures in response to almost any kind of brief stimulation, ranging from sounds, to visual images, to gentle touching of the skin. | | | Currently, fMRI is being used across the world as a powerful neuroscientific research tool to study how the brain works, although some medical applications are being discovered as well. | | | Conventional MRI images show beautifully detailed anatomy, and are an essential part of modern medicine. |
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http://www.hnl.bcm.tmc.edu/fMRI.html
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| | The fMRI Laboratory |
| | From a clinical perspective, fMRI is being used for pre- surgical planning in patients undergoing neurosurgical procedures. | | | Defining the relationship between brain structure and function is achieved through application of fMRI (functional magnetic resonance imaging). | | | The primary goal of the Toronto Western Hospital Functional Brain Imaging Center has been to promote translational research in fMRI, i.e. |
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http://www.uhnres.utoronto.ca/fmri/mainpage.htm
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| | [No title] |
| | BOLD fMRI is a relative technique in that it must compare images taken during one mental state to another to create a meaningful picture. | | | While there are currently no clinical indications for ordering any of these fMRI techniques, they hold considerable promise for unraveling the neurocircuitry and metabolic pathways of psychiatric disorders in the immediate future and in helping in psychiatric diagnosis and treatment planning down the road. | | | Perhaps most important for the future clinical utility of fMRI is that it involves only some upgrading of conventional MRI machines and, thus, may be become widely available. |
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http://www.musc.edu/psychiatry/fnrd/primer_fmri.htm
(4204 words)
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| | People @ Washington University Psychology |
| | Her research uses both behavioral (traditional psychological) and functional neuroimaging (specifically, fMRI) techniques. | | | In particular, his work focuses on using functional neuroimaging techniques (fMRI) to explore how brain areas are recruited when information is encoded into memory or explicitly retrieved from the recent past. | | | A second line of research explores how brain pathways change when a task is facilitated through practice. |
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http://www.artsci.wustl.edu/~psych/people.htm
(2939 words)
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| | Bibliography on Independent Component Analysis in Functional Neuroimaging |
| | Combining ICA and GLM: A hybrid approach to FMRI analysis. | | | Petersen, 2000] compared spatial and temporal ICA with the infomax, DCA and Molgedey-Schuster (MS-ICA): MS-ICA was found to be much faster than BS-ICA and DCA and DCA much slower. | | | Chuang, K.-H. and Chen, J.-H. Independent component analysis in the detection and correction of physiological artifacts in fMRI. |
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http://hendrix.imm.dtu.dk/staff/fnielsen/bib/Nielsen2001BibICA/Nielsen2001BibICA.html
(2856 words)
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| | FMRISTAT |
| | By default, the data is normalised at each voxel by dividing by the sd over time, so that the PCA is done in the spatial correlation matrix rather than the spatial covariance matrix (setting the parameter ISCOV=1 will give the unnormalised, covariance matrix analysis). | | | Worsley, K.J. Spatial smoothing of autocorrelations to control the degrees of freedom in fMRI analysis. | | | See Effective connectivity of all voxels with a reference. |
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http://www.math.mcgill.ca/keith/fmristat
(10036 words)
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| | Locating the Timekeeping Centers of the Brain |
| | Using a novel functional magnetic resonance imaging (fMRI) technique that tracks second-by-second changes in brain activity, investigators identified regions within the brain that are critical for this timekeeping system. | | | Contemporary theories of short interval timing assume the existence of a timekeeper system within the brain, yet identifying these brain systems has been elusive and controversial. | | | Seventeen healthy young men and women volunteers were imaged while being asked to perceive the duration of time between the presentations of two consecutive tones. |
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http://healthlink.mcw.edu/article/983222164.html
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| | Penn Researchers Discover The Powerful Tool Of Simultaneous fMRI And PET Imaging |
| | During the time that material is being taken up in the brain, radiologists are acquiring the fMRI image. | | | This analysis could lead to better diagnosis and treatment in patients suffering from brain disorders, like Alzheimer's disease. | | | Mayo Clinic Study Identifies Brain Changes In People Likely To Develop Alzheimer's Disease (July 28, 1999) -- A Mayo Clinic study has shown that 50 percent of a group of elderly patients with mild cognitive impairment who also have a significantly smaller hippocampus portion of the brain are likely to... |
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http://www.sciencedaily.com/releases/2005/10/051013081854.htm
(698 words)
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| | The Basics of Brain Imaging |
| | Thus researchers can make "movies" of changes in brain activity as patients perform various tasks or are exposed to various stimuli. | | | As a result, they can see whether brain activity occurs simultaneously or sequentially in different brain regions as a patient thinks, feels, or reacts to experimental conditions. | | | Within the last few years, scientists have developed techniques that enable them to use MRI to image the brain as it functions. |
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http://www.nida.nih.gov/NIDA_Notes/NNVol11N5/Basics.html
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| | Tutorial for MRIcro medical image freeware |
| | This technique is also useful for EPI fMRI images from healthy individuals (where EPI artifacts can also disrupt normalization). | | | For example, consider an fMRI study of auditory cortex. | | | Inati has also posted a useful technique for normalizing EPI scans with SPM. |
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http://www.psychology.nottingham.ac.uk/staff/cr1/mritut.html
(7928 words)
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| | Douglas C. Noll Home Page |
| | Projects include development of rapid image acquisition techniques such as spiral-scan MRI, analysis and elimination of physiological noise (cardiac, respiration) using acquisition and processing methods, elimination of movement artifacts through image registration, characterization of the fMRI temporal response to very short stimuli, and development of image processing and reconstruction methods. | | | In addition to methodological developments, I collaborate closely with cognitive neuroscientists and statisticians on the design of acquisition and processing methods for fMRI experiments. | | | My research is focused on the data acquisition and processing for imaging brain function using magnetic resonance imaging (functional MRI or fMRI). |
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http://www.eecs.umich.edu/~dnoll
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| | Bookmarks |
| | Research Newsletter of School of Medicine at QUB | | | fMRI / MRI / Analysis Labs on the Web |
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http://nlpr-web.ia.ac.cn/English/mic/med_im.html
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| | ABC News: Scientists Correlate Brain Activity with fMRI Signals |
| | "Our findings help validate the use of fMRI in a wide array of leading-edge neuroscience research in humans. | | | "Although functional magnetic resonance imaging is widely accepted as an important research tool, the relationship between fMRI signals in the human brain and the underlying neuronal activity has been unclear until now," study co-investigator Dr. Itzhak Fried, professor-in-residence of neurosurgery and psychiatry and biobehavioral sciences at UCLA, said in a prepared statement. | | | University of California, Los Angeles researchers first recorded the responses of single brain cells in the auditory cortex of two patients wired with intracranial electrodes as they viewed a nine-minute movie clip. |
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http://abcnews.go.com/Health/Healthology/story?id=1009954
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| | fMRI for Dummies |
| | Suggestions for Planning fMRI Experiments at RRI (html) | | | I am posting slides from a workshop on Experimental Design and Analysis that I gave to the Bergen fMRI Group in Norway. | | | Much of this site is still "Under Construction" and perhaps always will be... |
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http://defiant.ssc.uwo.ca/Jody_web/fmri4dummies.htm
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| | Independent Component Analysis: Applications to Biomedical Signal Processing |
| | Makeig S, Anllo-Vento L, Jung T-P, Bell AJ, Sejnowski TJ, and Hillyard SA, " Independent component analysis of event-related potentials during a selective attention task.", 36th Meeting of the Society for Psychophysiological Research, Vancouver, BC, Oct. 1996. | | | McKeown MJ, Makeig S, Brown GG, Jung T-P, Kindermann SS, and Sejnowski TJ, "Analysis of fMRI data by blind separation into independent spatial components", Human Brain Mapping, 6:160-188, 1998. | | | McKeown MJ, Makeig S, Jung T-P, Brown GG, Kindermann SS, and Sejnowski TJ, "Analysis of fMRI Data by Decomposition into Independent Components", Meeting of the American Academy of Neurology, abstract, 48, A417, 1997. |
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http://www.sccn.ucsd.edu/~scott/icabib.html
(4469 words)
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| | SPM - Statistical Parametric Mapping |
| | For fMRI the GLM is used in combination with a temporal convolution model. | | | For fMRI, analyses of effective connectivity can be implemented using Dynamic Causal Modelling DCM. | | | Parametric statistical models are assumed at each voxel, using the General Linear Model GLM to describe the data in terms of experimental and confounding effects, and residual variability. |
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http://www.fil.ion.ucl.ac.uk/spm
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| | Organization for Human Brain Mapping |
| | The meetings focus on neuroscience and on applications of these techniques to study brain implementation of sensory and motor systems, vision, attention, memory and language in normal and pathological states. | | | Consequently, discipline-specific conferences are not meeting the needs of this new convergence of research and disciplines and the OHBM conference is aimed at gathering scientists using modern, functional, brain mapping techniques such as PET, SPECT, fMRI, EEG, MEG, optical imaging and neuroanatomical tools for assessment of the functioning of the human brain. | | | The growth of human brain mapping cannot be attributed solely to increased productivity at well-established laboratories, but also to newly created functional-imaging centers and to scientists from a host of neighboring disciplines. |
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http://www.humanbrainmapping.org
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| | Wellcome Department of Imaging Neuroscience, UCL |
| | The Department came into being as an academic department of the Institute of Neurology in October 1994 to undertake research into the functional anatomy of the human brain in health and disease, using Positron Emission Tomographic (PET) and Functional Magnetic Resonance Imaging (fMRI) techniques. |
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http://www.fil.ion.ucl.ac.uk
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| | Neuroimaging Links |
| | University of Michigan FMRI laboratory - Dr. Douglas Noll's page with a link to his FMRI primer. | | | The FMRI Data Center - Aims to provide public acess to data from peer reviewed FMRI studies. | | | David - An online atlas of human anatomy for clinical imaging diagnosis. |
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http://www.neuropsychologycentral.com/interface/content/links/page_material/imaging/imaging_links.html
(675 words)
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| | Other Sites |
| | Schizophrenia and the brain - an fMRI study of brain volume: This is a link to a Nature article on MRI brain imaging in schizophrenia. | | | Brains.org: Hot topics in current brain research with references to the journals. | | | Contains info about the fMRI process, and links to PDF versions of recent publications by researchers in the lab - of you're keen. |
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http://www.science.mcmaster.ca/psychology/psych1a6/other_sites.html
(1516 words)
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| | Useful Software Collection |
| | PC Windows based fMRI postprocessing and analysis includeing cortex flattening (comercial) | | | Unix X-Window (XView) based fMRI postprocessing and analysis provided by CMRR | | | Unix based fMRI postprocessing and analysis including SPM and AIR (comercial) |
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http://mr.ee.ntu.edu.tw/~khchuang/software.html
(162 words)
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| | fMRIDC - Welcome to the fMRI Data Center |
| | October 6, 2005 - Free test images for use in assessing data processing routines | | | Computer Generated Phantoms for Use in Evaluating fMRI Methods | | | August 31, 2005 - Our thoughts go out to our dear friends |
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http://www.fmridc.org
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| | WATCHING THE BRAIN IN ACTION: Functional Topographic Mapping of the Cortex with Conventional MRI Scanners |
| | In demonstrations of this real-time brain-mapping capability, a test subject - one of the researchers - lies inside an MRI scanner at the University of Pittsburgh Medical Center and performs a simple mental task. | | | From the T3E, the data travels to a remote location via high-speed network, where observers see the subject's brain as a translucent animation showing what regions "light up" as she does the mental task. | | | The MRI scanner records data from her brain and transmits it via high-speed network to PSC's CRAY T3E, which converts the raw fMRI data into 3-D images, compensates for head movement and identifies active areas of the brain. |
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http://www.psc.edu/science/Goddard/goddard.html
(687 words)
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| | Neuroguide.com - Neuroscience Images |
| | Biophysics Research Institute, Medical College of Wisconsin (fMRI, functional neuroimaging) |
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http://www.neuroguide.com/neuroimg_3.html
(285 words)
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| | AFNI Main Page — AFNI and NIfTI Server for NIMH/NIH/PHS/DHHS/USA/Earth |
| | AFNI is a set of C programs for processing, analyzing, and displaying functional MRI (FMRI) data - a technique for mapping human brain activity. | | | It runs on Unix+X11+Motif systems, including SGI, Solaris, Linux, and Mac OS X. It is available free (in C source code format, and some precompiled binaries) for research purposes. | | | The most exciting spot on the Web (?). |
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http://afni.nimh.nih.gov/afni
(255 words)
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| | Harald Kerres Neuroimaging page |
| | Presentation on: Neurophysiological investigation of the basis of the fMRI signal | | | Neurophysiological investigation of the basis of the fMRI signal | | | If you like to keep up with the literature: |
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http://www.kerres.net
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| | Duke-UNC Brain Imaging and Analysis Center |
| | The Brain Imaging and Analysis Center (BIAC) has five openings for postdoctoral scientists to work on NIH-funded research. | | | 4/12/2005: BIAC paper "Abstinence-Induced Changes in Self-Report Craving Correlate With Event-related fMRI Responses to Smoking Cues" accepted for publication in Neuropsychopharmacology. | | | BIAC has recently completed construction of an MRI simulator system. |
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http://www.biac.duke.edu
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| | Clinical Image Processing Department - Software |
| | These ideas have been instantiated in software that is called SPM. | | | Inter-Repetition Variance Analysis - tool for running an FMRI analysis without specifying a waveform (also available from inside FEAT) | | | GIMP is an acronym for GNU Image Manipulation Program. |
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http://www.cc.nih.gov/cip/ip_packages/ip_packages.html
(3489 words)
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| | MRIcro software guide |
| | Overlays can also be used to check the coregistration of two images. | | | The 'Overlay' menu allows you to select an image which is superimposed on top of another image. | | | This is useful for displaying functional statistical maps (generated by SPM from PET, fMRI or SPECT data). |
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http://www.psychology.nottingham.ac.uk/staff/cr1/mricro.html
(7288 words)
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| | Imaging Home of Michael Rotte, best of fMRI MEG ERP |
| | ERP research is a wide, wild field due to the longest history of all imaging methods. | | | At our facility the Software package CURRY is used for statistical analysis and the transformation of structural and functional MRI imaging. | | | We have developed several tools for statistical mapping of fMRI and the combination of fMRI and MEG on the CURRY platform. |
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http://helios.med.uni-magdeburg.de/~rotte
(285 words)
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| | EPI and Functional MRI |
| | All told, however, the decided advantages of EPI in functional neuroimaging have placed it very much in demand for fMRI applications and have served to drive the technology development both in the academic research laboratory and with major commercial vendors, essentially all of whom now offer EPI products. | | | Notwithstanding the considerable efforts that have gone into EPI, there are still major advances to be gained. | | | Further, EPI can suffer from serious artifacts in shape distortion and image ghosts that require extra attention from the researcher. |
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http://airto.loni.ucla.edu/BMCweb/BMC_BIOS/MarkCohen/Papers/EPI-fMRI.html
(6497 words)
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| | fMRIDC |
| | Cornell University Laboratory of fMRI - Memorial Sloan-Kettering Cancer Center (MSKCC) | | | University of Helsinki, Finland BioMag Laboratory and fMRI |
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http://www.fmridc.org/resources/websites.html
(1052 words)
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| | Neurobehavioral Systems |
| | Check out Presentation® special features for experiments using psychophysics, eye movements, fMRI, ERP, MEG, single neuron recording, and more. | | | We're pleased to announce the beta release of some exciting new compressed video features: Detailed frame logging, multiple videos, videos with 3D and more! |
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http://www.neurobehavioralsystems.com
(125 words)
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| | [No title] |
| | An Introduction to Functional MRI and an fMRI Image Gallery | | | Deinococcus radiodurans J.R. Battista, Annual Review of Microbiology, 51, 203-224 (1997), AGAINST ALL ODDS: The Survival Strategies of Deinococcus radiodurans |
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http://www.phys.soton.ac.uk/teach/year2/notes/ph215/mplinks.htm
(309 words)
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| | Bergen fMRI Group - Nordic Center of Excellence |
| | Bergen fMRI Group - Nordic Center of Excellence | | | er en tverrfaglig forskningsgruppe ved Universitetet i Bergen og Haukeland Universitetssykehus innen functional Magnetic Resonance Imaging (fMRI). | | | fMRI-gruppen i Bergen har sammen med MR-senteret ved St.Olavs Hospital i Trondheim status som Nasjonalt Kompetansesenter for fMRI. |
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http://www.bergen-fmri-group.org
(139 words)
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| | Andrews' Software |
| | A perl script to convert, dump header contents and view (via MINC conversion) UNC files to MINC format. | | | ANALYZE is a commercial file format from the | | | SPM is a free fMRI toolkit from the |
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http://www.cmr.uq.edu.au/~rotor/software
(414 words)
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| | Brain Mapping Links |
| | The fMRI Network (an extraordinary collection of links) |
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http://www.brainmapping.org/BrainMapSites.html
(71 words)
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