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| | Journal of Drugs in Dermatology: Etanercept for the treatment of psoriasis: combination therapy with other modalities |
 | | This case describes a method of transitioning patients on cyclosporine to etanercept, with a gradual taper of the cyclosporine during the initiation of etanercept therapy. | | | After 20 weeks of etanercept monotherapy the patient was cleared of skin lesions. | | | Many psoriasis patients are already on other systemic therapies or have a medical history that necessitates a tailored approach to their therapy. |
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http://www.findarticles.com/p/articles/mi_m0PDG/is_3_3/ai_n6056502
(1385 words)
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| | Etanercept for rheumatoid arthritis |
| | Etanercept is used to treat severe rheumatoid arthritis when other medications have not been effective. | | | Etanercept is effective in relieving joint pain and swelling in rheumatoid arthritis that have not improved with methotrexate or other DMARDs. | | | Before starting etanercept treatment, you should be screened with a tuberculin skin test and a recent chest X-ray. |
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http://www.webmd.com/hw/rheumatoid_arthritis/aa18665.asp
(553 words)
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| | Etanercept news articles |
| | Humira (adalimumab), Remicade (infliximab), and Enbrel (etanercept) are mentioned in the study, which appears in the journal Arthritis Research and Therapy. | | | The investigators suggest that peritransplant administration of antithymocyte globulin and etanercept was responsible for the improved outcome. | | | Three of the newest drugs for AS are etanercept (Enbrel®), infliximab (Remicade®) and adalimumab (Humira®). |
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http://www.mongabay.com/drugs/drugs/Etanercept.html
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| | Clinical Trial: Etanercept for Treatment of Hidradenitis |
| | The secondary objective of this study is to determine the impact of etanercept treatment of hidradenitis suppurativa on skin related quality of life. | | | Another purpose of this study is to determine the impact of etanercept treatment of hidradenitis on skin related to quality of life. | | | The purpose of this study is to determine whether etanercept is safe and effective for the treatment of hidradenitis. |
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http://www.clinicaltrials.gov/ct/gui/show/NCT00107991
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| | MedlinePlus Drug Information: Etanercept (Systemic) |
| | While you are being treated with etanercept, do not have any immunizations (vaccinations) without your doctor's approval. | | | Mothers who are using this medicine and who wish to breast-feed should discuss this with their doctor. | | | It is important that your doctor check your progress at regular visits to make sure that this medicine is working properly and to check for unwanted effects. |
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http://www.nlm.nih.gov/medlineplus/druginfo/uspdi/203628.html
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| | Trial of Etanercept for Wegners's disease shows no benefit against the autoimmune condition |
| | To test the effectiveness of etanercept at preventing flare-ups for Wegener's patients, Stone and colleagues from seven other academic medical centers enrolled 180 patients with the disease into a randomized, placebo-controlled clinical trial. | | | In addition to standard therapies, 89 patients received etanercept and 91 received placebo. | | | "The study results, however, demonstrate unequivocally that etanercept was not effective for this purpose. |
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http://www.news-medical.net/?id=7536
(767 words)
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| | Arthritis Research & Therapy Full text Etanercept versus etanercept plus methotrexate: a registry-based study ... |
| | The decision whether to use etanercept monotherapy or combination therapy with MTX was based solely on clinical considerations by the responsible physician. | | | It is important to underscore that the comparison in this study is between, on the one hand, etanercept monotherapy initiated in patients who were not receiving disease-modifying antirheumatic drug therapy and, on the other hand, combination therapy where etanercept is added to established MTX therapy. | | | We analysed the clinical responses to treatment with etanercept either as monotherapy or when added to baseline therapy with MTX. |
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http://arthritis-research.com/content/5/6/R347
(2139 words)
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| | Arthritis Research Campaign Drugs for Arthritis: Etanercept |
| | You will have a chest x-ray and blood tests before starting treatment and then further blood tests while you are on etanercept to monitor its effects. | | | You may only take anti-inflammatory drugs if they are prescribed to you by your doctor. | | | If you would like any further information about etanercept, or if you have any concerns about your treatment, you should discuss this with your doctor, rheumatology nurse or pharmacist. |
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http://www.arc.org.uk/about_arth/infosheets/6259/6259.htm
(939 words)
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| | Arthritis (juvenile idiopathic) - etanercept (No. 35) |
| | At the moment there is no evidence from clinical studies to show how effective etanercept for the treatment of JIA is beyond 2 years. | | | Therefore the doctor should make a decision about whether to continue treatment with etanercept on the basis of how the child’s condition is progressing and how well the drugs are working. | | | The doctor who prescribes etanercept or infliximab should, with the parents’ and/or child’s consent, register the child with the Biologics Registry, which has been set up by the BPRG. |
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http://www.nice.org.uk/cat.asp?c=29662
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| | ACR: Switch from Sulfasalazine to Etanercept Beneficial in Rheumatoid Arthritis Treatment |
| | The safety of etanercept monotherapy was consistent with that observed in other RA studies of etanercept," the authors concluded. | | | A significantly higher percentage of subjects using etanercept as monotherapy (74 percent) or in combination (74 percent) achieved an ACR 20 response at 24 weeks, compared to the SSZ group (28 percent). | | | Thirty-three subjects left the study before endpoint, 9 patients taking etanercept, 7 taking etanercept+SSZ and 17 taking SSZ. |
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http://www.docguide.com/dg.nsf/PrintPrint/92C4101F89C5CB5085256C62006C4E84
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| | MedlinePlus Drug Information: Etanercept Injection |
| | When the syringe is empty, pull the needle out of the skin, being careful to keep it at the same angle as when it was inserted. | | | Talk to your doctor about the possible risks of using this medication for your condition. | | | Insert the needle straight down through the center ring of the gray stopper of the etanercept vial. |
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http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a602013.html
(1337 words)
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| | ETANERCEPT |
| | It is therefore not appropriate for general practitioners to prescribe etanercept. | | | This two-part study consisted of a 3-month open-label phase (n = 69) followed by a 4-month placebo-controlled double-blind treatment phase for patients whose condition improved. | | | Joint count was a primary outcome in one study. |
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http://www.keele.ac.uk/depts/mm/MTRAC/ProductInfo/summaries/E/ETANERCEPTs.html
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| | Etanercept |
| | Adequate studies involving interactions with other drugs have not been done. | | | Your doctor should instruct you on how to prepare and administer the injection of etanercept before you attempt to do it yourself. | | | The decision to stop taking the medication should be made in consultation with your doctor. |
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http://www.wholehealthmd.com/refshelf/drugs_view/1,1524,849,00.html
(460 words)
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| | Etanercept/anakinra RA combination therapy has increased risk compared to etanercept monotherapy - Formulary |
| | While patients in all treatment groups showed improvement from baseline at 24 weeks, therapy in the etanercept-only group resulted in 41% of patients achieving an ACR50 response, compared with 31% in the full-dosage etanercept plus anakinra group (P=.914, by 1-tailed t-test). | | | Etanercept/anakinra combination therapy for the treatment of rheumatoid arthritis (RA) provides no added benefit and has an increased risk compared to etanercept alone, according to a study published in Arthritis and Rheumatism, the journal of the American College of Rheumatology (ACR). | | | The primary end point was the proportion of patients achieving an ACR classification 50% (ACR50) response at Week 24. |
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http://www.actmagazine.com/formulary/article/articleDetail.jsp?id=128773
(527 words)
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| | News - Community Use of Etanercept in Psoriatic Arthritis Mirrors Outcomes From Phase Three Clinical Trials: Presented ... |
| | The goal of the phase 4 trial was to assess the efficacy and safety of etanercept when used in general practice. | | | NEW ORLEANS, LA -- February 21, 2005 -- Outcomes of the use of etanercept for psoriatic arthritis in community practice settings appear to be similar to the results seen in tightly controlled phase 3 clinical trials, researchers reported on February 20 | | | Community Use of Etanercept in Psoriatic Arthritis Mirrors Outcomes From Phase Three Clinical Trials: Presented at AAD |
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http://www.docguide.com/news/content.nsf/news/8525697700573E1885256FAF00713C2B
(698 words)
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| | IngentaConnect Use of Etanercept in the Dermatology Setting: A Review |
| | Etanercept provides dermatologists with a safe, effective, and convenient treatment option for patients with psoriatic arthritis and psoriasis, which can be used continuously with or without traditional therapies. | | | Dermatologists should be aware of the ongoing research with etanercept in psoriasis and other dermatologic conditions. | | | Keywords: Etanercept, therapeutic use; Psoriasis, treatment; Psoriatic arthritis, treatment |
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http://www.ingentaconnect.com/content/adis/derm/2005/00000006/00000001/art00006
(264 words)
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| | Etanercept for the treatment of rheumatoid arthritis. |
| | Thirty-nine percent of those receiving etanercept achieved an ACR 50 response compared to 4% of taking control treatment and the NNT is three. | | | What is etanercept (Enbrel) and why is it prescribed? | | | This Cochrane Review provides the best evidence we have today. |
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http://www.cochrane.org/reviews/en/ab004525.html
(878 words)
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| | Etanercept blunts proinflammatory effects of IL-2 therapy in HIV-infected patients |
| | All study subjects had undetectable or low-level HIV-1 RNA levels prior to etanercept treatment. | | | "Because TNF is postulated to be important in HIV disease progression, we designed this study to explore whether etanercept could block the activity of TNF," lead investigator Dr. Beverly E. Sha of Rush Medical College in Chicago, Illinois told Reuters Health. | | | Etanercept blunts proinflammatory effects of IL-2 therapy in HIV-infected patients |
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http://www.aidsmeds.com/news/20020620clin006.html
(421 words)
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| | (Enbrel) Etanercept |
| | Specific drug interaction studies have not been conducted with Etanercept. | | | Search our message boards and share experiences with others using Enbrel and possible side effects. | | | Etanercept is a Disease Modifying Anti Rheumatic Drug (DMARD), one of the new class called biologic response modifiers. |
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http://www.arthritisinsight.com/medical/meds/enbrel.html
(318 words)
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| | News - Two Etanercept Dosing Regimens Produce Comparable Outcomes in Patients With Rheumatoid Arthritis |
| | The researchers assessed efficacy and safety at weeks 8 and 16, and performed pharmacokinetic analyses on serum samples from patients at selected study sites. | | | The primary efficacy end point determined by whether or not patients met the American College of Rheumatology (ACR) 20% improvement criteria (ACR20 response) at week 8. | | | According to the researchers, the proportions of patients who experienced serious adverse events were similar in the 2 etanercept treatment groups. |
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http://docguide.com/news/content.nsf/news/8525697700573E1885256E3900353856
(523 words)
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| | Etanercept for plaque psoriasis - Formulary |
| | Etanercept should be administered with caution in patients with heart failure, and patients with heart failure should be monitored closely while receiving etanercept therapy. | | | Etanercept may be self-administered by the patient when deemed appropriate by a physician and if the patient receives medical follow-up as necessary. | | | Etanercept should not be administered to patients with sepsis, and administration of etanercept should be discontinued if a patient develops a serious infection or sepsis. |
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http://www.actmagazine.com/formulary/article/articleDetail.jsp?id=128752
(658 words)
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| | Etanercept (Enbrel). DermNet NZ |
| | However, current practice is to perform tuberculin skin testing for both drugs before commencing treatment. | | | A different site should be used at each injection to reduce soreness and prevent the skin from becoming tender, red, bruised or hard. | | | After initial counselling and training by a doctor on how to prepare and inject the drug, patients can usually self-administer at home. |
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http://www.dermnetnz.org/treatments/etanercept.html
(442 words)
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| | Treatment of Ankylosing Spondylitis with Etanercept (Enbrel) Johns Hopkins Arthritis News |
| | Etanercept is associated with a clear clinical response. | | | Unchanged for over a decade, the standard of care for ankylosing spondylitis has been a combination of physical therapy and nonsteroidal anti–inflammatory drugs (NSAIDs) and unproven agents such as sulfasalazine and methotrexate. | | | Results: Patients in the etanercept group showed significant improvement from baseline compared to patients in the placebo group in many measures of disease activity including C–reactive protein, erythrocyte sedimentation rate, morning stiffness, spinal pain, quality of life and functioning. |
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http://www.hopkins-arthritis.som.jhmi.edu/news-archive/2002/etanercept_spondylitis.html
(377 words)
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| | Clinical Trial: The Role of Cytokines on Growth Hormone Suppression in Premenopausal Women with Rheumatoid Arthritis ... |
| | Phase 2 of this study will be initiated upon access to etanercept and completion of Phase I of the study. | | | Etanercept is approved for the treatment of RA. | | | Phase II of the study, we shall enroll a new group of RA patients to evaluate the above outcome measures at baseline and after six months of treatment with standard therapy, using the soluble p75 TNF receptor molecule etanercept, that has recently been approved by the FDA for the treatment of patients with early RA. |
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http://www.clinicaltrials.gov/show/NCT00034060
(1260 words)
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| | Hotline - Etanercept (Enbrel) Label Updated Following Post-marketing Infectious Events |
| | Only one infection-related death (one of 745 patients or 0.13%) was observed in these clinical trials. | | | Etanercept was also approved by the FDA on May 28, 1999, for the treatment of JRA. | | | This frequency of serious infection was less than that observed in all clinical trials patients exposed to etanercept (3%). |
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http://www.rheumatology.org/publications/hotline/archive/0799adverse.asp?aud=mem
(837 words)
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| | Etanercept - Drugs & Vitamins - Drug Library - DrugDigest |
| | Check before stopping or starting any of your medications. | | | Etanercept is often given in combination with other agents to treat rheumatoid arthritis such as corticosteroids, anti-inflammatory drugs, methotrexate, and others. | | | Etanercept is also used to treat psoriatic arthritis, active ankylosing spondylitis, and psoriasis. |
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http://www.drugdigest.org/DD/DVH/Uses/0,3915,6100Etanercept,00.html
(782 words)
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| | Enbrel Eases Ankylosing Spondylitis |
| | WebMD Drug Reference from Multum Information Services: "Etanercept (injectable)." WebMD Medical Reference from Healthwise: "Ankylosing Spondylitis." | | | It typically strikes at a much younger age (early adulthood) than other forms of arthritis, and therefore people tend to suffer from the disease for much longer periods of time. |
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http://my.webmd.com/content/article/66/79650.htm
(554 words)
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| | Etanercept - Wikipedia, the free encyclopedia |
| | Inhibition of its action by etanercept reduces the inflammatory response which is especially useful for treating autoimmune diseases. | | | Etanercept mimics the inhibitory effects of naturally occurring soluble TNF receptors. | | | Etanercept is made from the combination of two naturally occurring soluble human 75-kilodalton TNF receptors linked to an Fc portion of an IgG1. |
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http://en.wikipedia.org/wiki/Etanercept
(261 words)
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| | Drug Combination Eases Rheumatoid Arthritis |
| | A new study showed that a combination therapy of Enbrel (etanercept) and methotrexate provided better relief from symptoms than individual treatment with the drugs. | | | The drug combination also led to complete remission of the disease in more than twice as many patients compared with those treated with either drug alone. |
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http://my.webmd.com/content/article/82/97430.htm
(433 words)
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| | Etanercept Scores Better In RA |
| | At 24 months, 72% of patients receiving 25 mg etanercept and 59% of patients receiving methotrexate met American College of Rheumatology criteria for 20% improvement (P=.005). | | | Improvement of at least 0.5 units on the Health Assessment Questionnaire disability index occurred in 55% of patients receiving 25 mg etanercept but in only 37% of patients receiving methotrexate (P | | | The researchers state that etanercept as monotherapy was safe and was superior to methotrexate in reducing disease activity, arresting structural damage and decreasing disability over a period of two years in patients with early and aggressive RA. |
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http://www.indegene.com/End/Home/indEnd_Ind_News_02-07-2002_1.asp
(210 words)
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| | Hotline - Etanercept Patient Enrollment |
| | Etanercept Patient Enrollment The American College of Rheumatology has been notified by Immunex Corp. of a potential etanercept drug supply issue. | | | They have announced an enrollment program to help ensure uninterrupted future drug availability for those patients currently receiving etanercept. | | | This Hotline reflects the views of the author(s) and does not represent a position statement of the College. |
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http://www.rheumatology.org/publications/hotline/1200enrollment.asp
(225 words)
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| | Enbrel Online, Description, Chemistry, Ingredients - Etanercept - RxList Monographs |
| | Etanercept is produced by recombinant DNA technology in a Chinese hamster ovary (CHO) mamalian cell expression system. | | | (etanercept) is a dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1. | | | It consists of 934 amino acids and has an apparent molecular weight of approximately 150 kilodaltons. |
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http://www.rxlist.com/cgi/generic/etanercept.htm
(271 words)
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| | MedlinePlus Medical Encyclopedia: Arthritis |
| | Such medications, including etanercept (Enbrel), infliximab (Remicade) and adalimumab (Humira), are administered by injection and can dramatically improve your quality of life. |
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http://www.nlm.nih.gov/medlineplus/ency/article/001243.htm
(1802 words)
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| | Letter - Enbrel |
| | (etanercept), a new treatment for moderate to severe rheumatoid arthritis. | | | Some of this safety information was already described in the package insert. |
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http://www.fda.gov/medwatch/safety/1999/enbrel.htm
(802 words)
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