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Topic: Erythropoietin



  
 Erythropoietin, iron, and erythropoiesis -- Goodnough et al. 96 (3): 823 -- Blood
Erythropoietin therapy in patients on dialysis is associated with the progressive appearance of hypochromic, microcytic erythrocytes.
Erythropoietin response to anaemia is not altered by surgery or recombinant human erythropoietin therapy.
The erythropoietic response to erythropoietin therapy in patients with rheumatoid arthritis.
http://www.bloodjournal.org/cgi/content/full/96/3/823   (6165 words)

  
 EPO - Erythropoietin precursor
Juvenile hemochromatosis associated with B-thalassemia treated by phlebotomy and recombinant human erythropoietin.
Recombinant human erythropoietin enhances vasoconstrictor tone via endothelin-1 and constrictor prostanoids.
These findings suggest that MSP has the ability to enhance erythroid colony formation in response to Epo, and that this response is dependent on the ability of MSP to induce the MAP kinase pathway.
http://www.ihop-net.org/UniPub/iHOP/gg/88017.html   (4814 words)

  
 Erythropoietin stimulators - [Medication] - Quest Diagnostics Patient Health Library
This is the most common reason that erythropoietin stimulators may not be effective.
This is the most common use of this therapy.
The use of erythropoietin stimulators may also delay the need for dialysis, improve some heart problems, and increase your life span.
http://www.questdiagnostics.com/kbase/topic/detail/drug/tv6913/detail.htm   (438 words)

  
 Erythropoietin for anemia in IBD
This study was a randomized, double-blind trial of recombinant erythropoietin (epoietin) in treating patients with inflammatory bowel disease and anemia refractory to iron therapy.
In an article from the May 15, 1997 Annals of Internal Medicine (from one of the groups that authored this study), the use of intravenous iron with and without erythropoietin was examined in Crohn's Disease.
At 12 weeks, 82% of patients randomized to treatment had response to therapy (increase of Hgb by 1.0 g/dl), as compared with 24% in the placebo group.
http://www.journalclub.org/vol1/a16.html   (1058 words)

  
 ERYTHROPOIETIN
The increases in haemoglobin and haematocrit seen with erythropoietin therapy are associated with clinical benefits recorded as improvements in quality of life (QOL), functional ability, exercise capacity, vitality, and work capacity.
The first clinical trials with recombinant erythropoietin therapy were published in 1986/87.
Evidence-based Recommendations for the Clinical Use of Recombinant Human Erythropoietin.
http://www.keele.ac.uk/depts/mm/MTRAC/ProductInfo/summaries/E/ERYTHROPOIETINs.html   (990 words)

  
 The interaction of iron and erythropoietin
Iron stores were quite high in these early subject all of whom had been on maintenance transfusion therapy prior to the introduction of erythropoietin.
A study by Rutherford and colleagues in 1994 dramatically demonstrated the interplay between iron and erythropoietin (Rutherford, et al.
Careful evaluation of the subject's iron stores is necessary to utilize erythropoietin most effectively.
http://sickle.bwh.harvard.edu/iron_epo.html   (2239 words)

  
 Gale Encyclopedia of Cancer: Erythropoietin
In clinical studies erythropoietin did not have any drug interactions.
Blood counts will be monitored before receiving erythropoietin and regularly while on the drug erythropoietin.
Blood pressure should also be monitored regularly while on erythropoietin.
http://www.findarticles.com/p/articles/mi_gGEC/is_0011/ai_2699001159   (979 words)

  
 Baker Institute : Research : Former Faculty : James MacLeod : Anemia/Erythropoietin: Companion Animal Erythropoietin
Our work with canine erythropoietin was initiated first, so the efficacy and safety experiments completed to date have been primarily in dogs.
Our research is based on the hypothesis that species-specific erythropoietin preparations are needed to avoid the immunogenicity problems of rhEPO in veterinary applications.
Comparison of the biologic activity and safety of recombinant canine erythropoietin to recombinant human erythropoietin in normal Beagle dogs.
http://bakerinstitute.vet.cornell.edu/research/macleod/anemia.html   (793 words)

  
 Predicting Response to Recombinant Human Erythropoietin -- Robert I. and David H. 119 (1): 91 -- Annals of Internal ...
Recombinant human erythropoietin in the treatment of anemia associated with human immunodeficiency virus (HIV) infection and zidovudine therapy.
Predicting Response to Recombinant Human Erythropoietin -- Robert I. and David H. 119 (1): 91 -- Annals of Internal Medicine
serum erythropoietin levels between 100 and 500 IU/L had a response
http://www.annals.org/cgi/content/full/119/1/91-a   (319 words)

  
 Diabetes: Erythropoietin and Progressive Kidney Disease
However, there have been no studies that prove that erythropoietin is safe and effective for those with progressive renal disease.
Based on what we know now, however, it seems that a hematocrit of 35-38% would be safe, effective, and in most cases, easy to attain.
On the other hand, the conservative "wait until proven" philosophy may deny a helpful -- or even life-saving -- therapy to an entire generation of patients.
http://www.thedoctorwillseeyounow.com/articles/diabetes/erythro_4   (1329 words)

  
 Erythropoietin (EPO) factsheet
This fact sheet explains what erythropoietin (EPO) is, how it is given and some of the possible side effects.
Keep erythropoietin, like all medicines, in a safe place out of the reach of children.
Parents and older children can be taught to give the injections or your community or practice nurse can give them.
http://www.gosh.nhs.uk/factsheets/families/F000377   (705 words)

  
 Erythropoietin: A Paradigm for the Development of Practice Guidelines -- Rizzo et al. 2001 (1): 10 -- Hematology
Clinical studies of recombinant human erythropoietin (rHuEpo) in patients with myeloma and lymphoma.
The role of erythropoietin is still being defined.
of erythropoietin, which may be influenced by practice setting
http://www.asheducationbook.org/cgi/content/full/2001/1/10   (9607 words)

  
 Erythropoietin
It has also been reported to facilitate autologous blood donation prior to elective surgery, but the utility of this approach is somewhat limited.
The Institute for Transfusion Medicine is offering a full-day seminar on Saturday, September 23, 1995, entitled "Transfusion Medicine Update-1995." The seminar will be held at the Sheraton Hotel, Station Square in Pittsburgh.
about erythropoietin, please contact Dr. Kiss at (412) 622-7294 or Dr. Faruki at (412) 622-7291.
http://path.upmc.edu/consult/rla/july1995.html   (735 words)

  
 Developmental regulation of erythropoietin and erythropoiesis -- Moritz et al. 273 (6): 1829 -- AJP - Regulatory, ...
Effects of recombinant human erythropoietin in infants with the anemia of prematurity.
Double blind trial of recombinant human erythropoietin in preterm infants.
Renal and extrarenal erythropoietin production in anaemic rats.
http://ajpregu.physiology.org/cgi/content/full/273/6/R1829   (7486 words)

  
 Erythropoietin: Molecular Biology and Clinical Use
22 Use of Erythropoietin in the Surgical Patient
23 Regulation of Erythropoiesis and Erythropoietin Therapy in
PHYSIOLOGY AND PATHOPHYSIOLOGY OF 9 Erythropoietin Regulation in Humans During Exercise and in
http://www.fpgrahamco.com/Pages/054.html   (263 words)

  
 Erythropoietin (EPO)
Erythropoietin response to anemia (excluding renal disease and pregnancy) in older subjects is similar to that of younger subjects.
Hazards: Therapeutic administration of erythropoietin has been associated with vascular thrombosis.
The effectiveness of recombinant erythropoietin in the treatment in other types of refractory anemia is under evaluation.
http://www.labcorp.com/datasets/labcorp/html/chapter/mono/sr005800.htm   (732 words)

  
 Erythropoietin receptor signalling is required for normal brain development -- Yu et al. 129 (2): 505 -- Development
(F) Induction of phosphorylation of Jak2 and STAT5 in cortical neurons treated with erythropoietin cultured at 20% or 2% oxygen tension was examined.
A specific survival role for erythropoietin and induction
neurons producing EpoR (I); no erythropoietin response was observed in Epor
http://dev.biologists.org/cgi/content/full/129/2/505   (7026 words)

  
 Erythropoietin
Recombinant erythropoietin therapy can be highly effective in a number of anemias, especially those associated with a poor erythropoietic response.
Malnutrition, which is a common finding in dialysis patients.
There is a clear dose response relationship between epoetin alfa dose and the rise in hematocrit in anephric patients with eradication of their anemia at higher doses.
http://www.med.howard.edu/pharmacology/handouts/Erthropoetin_Hemo1.htm   (4115 words)

  
 Erythropoietin (Epogen®, Procrit®) - PetPlace.com
Consult with your veterinarian to determine if other drugs your pet is receiving could interact with erythropoietin.
The primary use of erythropoietin is to treat anemia associated with chronic kidney failure.
The duration of administration depends on the condition being treated, response to the medication and the development of any adverse effects.
http://petplace.netscape.com/articles/artShow.asp?artID=1504   (477 words)

  
 Chemical & Engineering News: Top Pharmaceuticals: Erythropoietin
Generally, EPO might be prescribed for any condition where blood oxygen levels are depressed and to help eliminate the potential need for blood transfusions.
Understanding the function of endogenous hormones and putting them to good use to treat diseases has been one of the great accomplishments of modern medicine.
One natural hormone that has turned out to be a blockbuster drug--but not without some controversy--is erythropoietin (EPO).
http://pubs.acs.org/cen/coverstory/83/8325/8325erythropoietin.html   (893 words)

  
 UK NKF - Drugs
Nearly half the people on dialysis take this drug.
The drug Erythropoietin is an artificial version of this hormone which can boost the body to make red blood cells.
When someone's kidneys don’t work, the kidneys produce less EPO and so the person becomes anaemic.
http://www.kidney.org.uk/Medical-Info/drugs/epoinfo.html   (340 words)

  
 Erythropoietin - Wikipedia, the free encyclopedia
Epogen and Procrit are 2 US brands; at least one has been advertised on television as a treatment for tiredness in cancer patients.
Erythropoietin is also sometimes given in advance of a surgical operation for patients who cannot or do not wish to receive blood transfusions, such as Jehovah's Witnesses, in an attempt to increase the body's red blood count to an extent sufficient to counteract possible blood loss during the operation without requiring a transfusion.
It is most often given to people with anemia associated with chronic renal failure, but can be beneficial in many types of anemia due to diseases that interfere with RBC production, such as that due to cancer chemotherapy.
http://en.wikipedia.org/wiki/Erythropoietin   (1129 words)

  
 erythropoietin
While anemia can have many causes, reduced levels of erythropoietin or treatments affecting bone marrow are leading causes.
There are close to 100 different causes of anemia, including serious illness, vitamin or iron deficiencies, blood loss, genetic or acquired disease, or side effects of medication.
Chemotherapy and radiation treatment, for example, are both designed to kill cancer cells but also can kill or damage healthy cells as well, including red blood cells.
http://www.anemia.com/erythropoietin.html   (167 words)

  
 Epo - Drugs & Vitamins - Drug Library - DrugDigest
Sometimes, your body does not make enough erythropoietin, and that may cause anemia.
Epoetin alfa acts treats anemia associated with chronic kidney failure, cancer chemotherapy, or HIV-therapy.
A health-care professional in a hospital or clinic setting may give it to you.
http://www.drugdigest.org/DD/DVH/Uses/0,3915,234Epo,00.html   (716 words)

  
 Procrit Online, Description, Chemistry, Ingredients - Erythropoietin - RxList Monographs
It has a molecular weight of 30,400 daltons and is produced by mammalian cells into which the human erythropoietin gene has been introduced.
Erythropoietin is a glycoprotein which stimulates red blood cell production.
It is produced in the kidney and stimulates the division and differentiation of committed erythroid progenitors in the bone marrow.
http://www.rxlist.com/cgi/generic/epoetin.htm   (331 words)

  
 [No title]
Recombinant erythropoietin used for manufacturing the therapeutic form may contain not more than 10 pg of DNA per 10 000 IU (data from Cilag).
Results of analysis of five samples demonstrate the content of monomeric form in Epo substance to be not less than 99% of total erythropoietin, i.e.
epo human recombinant erythropoietin HIV AIDS doping in sportmedicine immunesystem gene biotechnology technologytransfer license production of erythropoietin, how to receive the license for its production are the points of the website.
http://www.potence.de/erythropoietin   (6354 words)

  
 MedlinePlus Medical Encyclopedia: Erythropoietin
This test may be used to help determine the cause of anemia, polycythemia (high red blood cells) or other bone marrow disorders.
These cells are sensitive to the oxygen concentration in the blood, and increase the release of EPO when the oxygen concentration is low.
This is a test to measure the amount of erythropoietin in blood.
http://www.nlm.nih.gov/medlineplus/ency/article/003683.htm   (685 words)

  
 Erythropoietin - Current Market Dynamics & Future Outlook
Many licensing opportunities for fully developed generics versions of epoetin alfa are available.
Written with the senior executive needs in mind, Erythropoietin - Current Market Dynamics & Future outlook, is a must read for pharmaceutical and medical biotech professionals interested in high growth area therapeutics or in Biogenerics.
The market has been growing at an average annual growth rate of 21% over the previous 5 years.
http://www.mindbranch.com/catalog/product.jsp?partner=213&code=R223-018   (389 words)

  
 Erythropoietin
Prosecutors in court Thursday referred to two local doctors as licensed drug dealers for their alleged inolvement in a prescription drug ring, Local 4 reported.
At eBay you can find practically anything, even erythropoietin.
Find results for erythropoietin and anything else you are looking for instantly!
http://haxwax-medications.com/Erythropoietin.html   (552 words)

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