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| | British Journal of Pharmacology - Upregulation by glucocorticoids of responses to eosinopoietic cytokines in ... |
 | | Despite stimulation of myelopoiesis, we have focused on the eosinophil lineage because of its relevance to allergy and asthma, which are treated with glucocorticoids. | | | This may be of relevance in conditions in which the synthesis of these cytokines becomes resistant to glucocorticoids (Kunicka et al., 1993; Her et al., 1991) or is induced by glucocorticoids (Wilckens and De Rijk, 1997; Agarwal and Marshall, 1998). | | | Such studies can be carried out after the numbers of progenitors in peripheral blood are artificially increased by a number of treatments (see, for instance, Roberts et al., 1997), but they are difficult to carry out in normal animals, which were central to our study. |
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http://www.nature.com/bjp/journal/v129/n8/full/0703145a.html
(6595 words)
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| | The mechanism of IL-5 signal transduction -- Adachi and Alam 275 (3): 623 -- AJP - Cell Physiology |
| | Requirement of Lyn and Syk tyrosine kinases for the prevention of apoptosis by cytokine in human eosinophils. | | | IL-5 enhances the in vitro adhesion of human eosinophils, but not neutrophils, in a leukocyte integrin (CD11/18)-dependent manner. | | | Synergy between dexamethasone and interleukin-5 for the induction of major histocompatibility complex class II expression by human peripheral blood eosinophils. |
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http://ajpcell.physiology.org/cgi/content/full/275/3/C623
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| | Faculty |
| | Our research interests center on the molecular biology, biochemistry and hematopoietic development of the human eosinophil leukocyte in health and disease pathogenesis. | | | Eosinophil effector functions in inflammation, tissue remodeling, and fibrosis in asthma, allergy, and other eosinophil-associated diseases. | | | Related projects characterizing eosinophil effector mechanisms in the pathophysiology of asthma and other allergic diseases include studies of the mechanisms by which eosinophils induce airways dysfunction, fibroblast and epithelial cell activation, and the production of inflammatory cytokines and other mediators of tissue remodeling and pathological tissue fibrosis in the lung, gastrointestinal tract and other tissues. |
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http://www.uic.edu/com/bcmg/ackerman.html
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| | eosinophil: Definition and Much More From Answers.com |
| | This is the most widely used histological stain in medical diagnosis - for example when a pathologist looks at a biopsy of a suspected cancer they will have the section stained with HandE | | | Eosinophilic is a technical term used by histologists. | | | Some structures seen inside cells are described as being eosinophilic, for example LEWY BODY, MALLORY BODY. |
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http://www.answers.com/eosinophils
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| | Theses from Uppsala University : 2059 - Eosinophil Cationic Protein |
| | Asthma and HL-NS are characterized by fibrosis and eosinophils and ECP has been suggested in fibrosis development. | | | Eosinophils, Neutrophils, Monocytes, Macrophages, mRNA, eosinophil cationic protein, DNA, polymorphism, Hodgkin Lymphoma, asthma, allergy |
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http://publications.uu.se/theses/abstract.xsql?dbid=2059
(701 words)
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| | Eosinophil granulocyte interaction with serum-opsonized particles: binding and degranulation are enhanced by tumor ... |
| | Eosinophils participate in the inflammatory response seen in allergy and helminthic infestation. | | | Eosinophil granulocyte interaction with serum-opsonized particles: binding and degranulation are enhanced by tumor necrosis factor alpha.Their release of granule-bound cationic proteins may play a role in these diseases. | | | Tumor necrosis factor-alpha (TNF-alpha) and interleukin (IL)-5 both rapidly enhanced the binding of eosinophils to serum-opsonized zymosan, and also the release of ECP upon interaction with SOS. |
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http://www.pdg.cnb.uam.es/UniPub/iHOP/gp/1320210.html
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| | Anna Nopp: Doktorsavhandling från Karolinska Institutet |
| | To further examine the apoptosis process in eosinophils, we analysed eosinophils from allergic and non-allergic individuals, and we found an increased survival in cells from allergic individuals as compared to non-allergic individuals. | | | Our hope is that these results may eventually contribute to the identification of a drug that can selectively induce apoptosis in eosinophils without causing activation and degranulation, thus decreasing the pathophysiological effect of eosinophils both in the acute inflammation, as well as in the process of tissue remodelling after injury. | | | This thesis focuses on identification of eosinophil activity markers of importance for the clinical evaluation of allergic inflammation, as well as the relation between activation and prolonged survival of the eosinophil granulocyte. |
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http://diss.kib.ki.se/2002/91-7349-129-2
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| | Inst för medicinska vetenskaper |
| | Mechanisms of human eosinophil adhesion, apoptosis, metabolism, migration, secretion and the role of the eosinophil in health and disease (e.g., asthma, rhinitis, inflammatory bowel disease and cancer) | | | For over 20 years, the research at our department has been devoted to the study of inflammation in general and the role of the two white blood cells in humans, the eosinophil granulocyte and the neutrophil granulocyte, as well as their functions and biochemistry in health and disease in particular. | | | The biochemistry and molecular biology of Eosinophil Cationic Protein (ECP) |
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http://www.medsci.uu.se/fogrupp/inflammation/inflammationgroup.htm
(140 words)
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| | Neutrophil granulocyte -- Facts, Info, and Encyclopedia article |
| | PMNs in turn account for 70% of all leukocytes in humans. | | | This can be (Click link for more info and facts about congenital) congenital ((A disease or disorder that is inherited genetically) genetic disorder) or due to acquired factors. | | | They are the most common PMNs (polymorphonuclear cells, see (A leukocyte that has granules in its cytoplasm) granulocytes), constituting about 99% of circulating PMNs. |
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http://www.absoluteastronomy.com/encyclopedia/n/ne/neutrophil_granulocyte.htm
(472 words)
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| | Diagnostics development myeloperoxidase ecp edn epx hnl ngal elisa |
| | antibodies, antigen, elisa, myeloperoxidase, mpo, ecp, eosinophil cationic protein, epx, edn, eosinophil protein x, eosinophil-derived neurotoxin, hnl, ngal, human neutrophil lipocalin, neutrophil gelatinase associated lipocalin, eosinophil peroxidase, epo, lysozyme, diagnostics development, uppsala |
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http://www.diagnosticsdevelopment.com
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| | Granulocyte eosinophil |
| | Eosinophils es las células de sangre blancas que son responsables de combatir la infección por los parásitos en el cuerpo. | | | Eosinophils también tiene un papel en luchar infecciones virales que es evidente de la abundancia de RNAses que él contiene dentro de sus gránulos. | | | Eosinophils también desempeña un papel en la respuesta alérgica, y en retiro del fibrin en inflammation.Eosinophils se consideran las células effector principales en patogenesia del asma y se asocian a severidad de la enfermedad. |
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http://www.yotor.net/wiki/es/gr/Granulocyte%20eosinophil.htm
(186 words)
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