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Topic: Eosinophil


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 Pharmacology of the Eosinophil -- Giembycz and Lindsay 51 (2): 213 -- Pharmacological Reviews
is a potent chemoattractant for human eosinophils, with
Further description of the morphology of eosinophils in health and disease is beyond the scope of this review, but interested
demonstrated that >95% of the eosinophil's response evoked by
http://pharmrev.aspetjournals.org/cgi/content/full/51/2/213   (5736 words)

  
 VCAM-1 is more effective than MAdCAM-1 in supporting eosinophil rolling under conditions of shear flow -- Sriramarao et ...
The ability of the rolling eosinophils to adhere firmly in postcapillary venules (treated with anti-VCAM-1 mAb Rb 1/9 or control antibody (IgG1) (as described in Figure 7) was determined.
The ability of eosinophils to interact with VCAM-1 at physiologic conditions of shear force was examined using a parallel
Functional and structural characterization of the eosinophil P-selectin ligand.
http://www.bloodjournal.org/cgi/content/full/95/2/592   (6947 words)

  
 Perturbations in Eosinophil Homeostasis following Treatment of Lymphatic Filariasis -- Gopinath et al. 68 (1): 93 -- ...
Much of the information to date on eosinophil behavior and degranulation has been obtained in vitro.
IL-5 as a strong secretagogue for human eosinophils.
Interactions between human eosinophils and schistosomula of Schistosoma mansoni.
http://iai.asm.org/cgi/content/full/68/1/93   (4626 words)

  
 Cultured Human Airway Smooth Muscle Cells Stimulated by Interleukin-1beta Enhance Eosinophil Survival -- Hallsworth et ...
Points represent means ± SEM of duplicate values from independent experiments using conditioned medium from airway smooth muscle cells cultured from three patients.
Points represent means ± SEM of duplicate values from independent experiments using conditioned medium from airway smooth muscle cells cultured from five patients.
Points represent means ± SEM of duplicate values from independent experiments using conditioned medium from airway smooth muscle cells cultured from seven patients.
http://ajrcmb.atsjournals.org/cgi/content/full/19/6/910   (5962 words)

  
 Essential and Instructive Roles of GATA Factors in Eosinophil Development -- Hirasawa et al. 195 (11): 1379 -- The ...
eosinophils are indicated as mean ± SD of three representative experiments.
GATA-1 and GATA-2 are predominantly expressed in eosinophils
could be the critical determinant for eosinophil lineage commitment.
http://www.jem.org/cgi/content/full/195/11/1379   (3963 words)

  
 Regulation of Human Eosinophil Migration Across Lung Epithelial Monolayers by Distinct Calcium Signaling Mechanisms in ...
of human eosinophils across lung epithelium remain to be elucidated.
responses to chemoattractants are vital for eosinophil migratory
of human eosinophils across a monolayer of human lung epithelial
http://www.jimmunol.org/cgi/content/full/163/10/5649   (4838 words)

  
 LPS Induces Eosinophil Migration via CCR3 Signaling Through a Mechanism Independent of RANTES and Eotaxin -- Penido et ...
Samples were immediately analyzed on a FACScalibur flow cytometer (Becton Dickinson).
but not eosinophil, recruitment in response to LPS.
was determined by an eosinophil shape change assay as described
http://ajrcmb.atsjournals.org/cgi/content/full/25/6/707   (5900 words)

  
 Effects of Budesonide and Formoterol on Eosinophil Activation Induced by Human Lung Fibroblasts -- SPOELSTRA et al. 162 ...
IL-5 as a strong secretagogue for human eosinophils.
The results of the present study imply that for the daily practice of asthma therapy, the use of budesonide has beneficial
The latter observation is apparently in contrast to
http://ajrccm.atsjournals.org/cgi/content/full/162/4/1229   (3366 words)

  
 Encyclopedia: Eosinophil granulocyte
The intestine is the portion of the alimentary canal extending from the stomach to the anus and, in humans and mammals, consists of two segments, the small intestine and the large intestine.
Eosinophils are considered the main effector cells in asthma pathogenesis and are associated with disease severity.
A toxin, in a scientific context, is a biologically produced substance that causes injury to the health of a living thing on contact or absorption, typically by interacting with biological macromolecules such as enzymes and receptors.
http://www.nationmaster.com/encyclopedia/Eosinophil-granulocyte   (1952 words)

  
 Variations in Eosinophil Chemokine Responses: An Investigation of CCR1 and CCR3 Function, Expression in Atopy, and ...
investigated the functional role of CCL3 in eosinophil responses
Identification of a functional CCR1 promoter will facilitate
Variations in Eosinophil Chemokine Responses: An Investigation of CCR1 and CCR3 Function, Expression in Atopy, and Identification of a Functional CCR1 Promoter
http://www.jimmunol.org/cgi/content/abstract/170/12/6190   (416 words)

  
 British Journal of Pharmacology - Abstract of article: Nitric oxide regulates human eosinophil adhesion mechanisms in ...
Human peripheral blood eosinophils were treated with L-NAME (0.01 − 1.0 mM) and their adhesion to human fibronectin and serum observed.
This inhibition is accompanied by a decrease in the expression and function of the eosinophil's adhesion molecules, in particular, the expression of the Mac-1 integrin and the function of the VLA-4 integrin.
Nitric oxide regulates human eosinophil adhesion mechanisms in vitro by changing integrin expression and activity on the eosinophil cell surface
http://www.nature.com/bjp/journal/v134/n3/abs/0704295a.html   (400 words)

  
 HON Allergy Glossary Eosinophil
Produced in the bone marrow, eosinophils then migrate to tissues throughout the body.
Eosinophil secretory products inactivate many of the chemical mediators of inflammation and destroy cancer cells.
When a foreign substance enters the body, lymphocytes and neutrophils release certain substances to attract eosinophils which release toxic substances to kill the invader.
http://www.hon.ch/Library/Theme/Allergy/Glossary/eosinophil.html   (103 words)

  
 MedlinePlus Medical Encyclopedia: Eosinophil count - absolute
Cotton or a bandage may be applied to the puncture site if there is any continued bleeding.
Increased eosinophils (eosinophilia) is most often associated with allergic diseases and parasites (such as worms).
Fewer than normal eosinophils may be associated with:
http://www.nlm.nih.gov/medlineplus/ency/article/003649.htm   (690 words)

  
 Eosinophil activation and preschool viral wheeze -- Oommen et al. 58 (10): 876 -- Thorax
from PVW suggests a role for eosinophils in the pathogenesis
Assessment of eosinophil granule proteins in various body fluids: is there a relation to clinical variables in childhood asthma?
Figure 4 Change in urinary eosinophil protein X (uEPX) levels between the acute and convalescent phase of PVW.
http://thorax.bmjjournals.com/cgi/content/full/58/10/876   (2453 words)

  
 Eosinophil Count
Decreased eosinophils occurs in adrenal cortical hyperplasia (Cushing syndrome), cortisone therapy, hormone-secreting tumors, intermenstrual period, acute and chronic inflammation, and anoxia.
Usually increased in allergy, parasitic infestations, tuberculosis, brucellosis, collagen disease, Hodgkin's disease, myeloproliferative diseases, and the acute hypereosinophilic syndrome; increased also in angioneurotic edema, dermatitis, thymic disorders, radiotherapy, splenectomy, convalescence from a febrile illness, and hypoadrenocorticism (Addison disease).
This condition may not be a true leukemic myeloproliferative disease, although concepts of HES are controversial.
http://www.labcorp.com/datasets/labcorp/html/chapter/mono/he001900.htm   (537 words)

  
 Eosinophil-Associated Inflammation and Elaboration of Eosinophil-Derived Proteins in 2 Children With Raccoon Roundworm ...
Both patients had rapidly progressive central nervous system disease with evidence of eosinophilic meningoencephalitis.
Neither patient was seropositive for Toxocara canis or lived
IL-5 also functions as a chemoattractant for eosinophils
http://pediatrics.aappublications.org/cgi/content/full/108/5/e93   (2971 words)

  
 eosinophil - definition of eosinophil by the Free Online Dictionary, Thesaurus and Encyclopedia.
eosinophil - a leukocyte readily stained with eosin
This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional.
A type of white blood cell found in vertebrate blood, containing cytoplasmic granules that are easily stained by eosin or other acid dyes.
http://www.thefreedictionary.com/eosinophil   (141 words)

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