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| | ERAF - Alpha-hemoglobin stabilizing protein |
 | | Relaxation in response to the bradykinin stimulus was abolished in the presence of L-nitroarginine methyl ester, a specific inhibitor of the synthesis of endothelium-derived relaxing factor ( EDRF). | | | It is concluded that endothelin-1 contractions of rat aorta are modified by the endothelium, probably by enhancing the release of endothelium-derived relaxing factor ( EDRF) and not by affecting the sensitivity of the smooth muscle to EDRF. | | | We conclude that bradykinin relaxes human CC by releasing EDRF and that this EDRF may be a factor in erectile function. |
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http://www.pdg.cnb.uam.es/UniPub/iHOP/gg/99374.html
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| | Robert Furchgott |
| | After the discovery that relaxation by EDRF is associated with a rise in cGMP in the vascular smooth muscle, we found that photorelaxation of arterial smooth muscle (using near UV radiation) is also associated with a rise in cGMP, which precedes the relaxation. | | | Furchgott, R. Studies on relaxation of rabbit aorta by sodium nitrite: the basis for the proposal that the acid-activatable inhibitory factor from retractor penis is inorganic nitrite and the endothelium-derived relaxing factor is nitric oxide. | | | This factor was called the endothelium-derived relaxing factor (EDRF). |
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http://www.hscbklyn.edu/pharmacology/furch.htm
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| | Hull 1994b |
| | Endothelium derived relaxing factor (EDRF), now widely belived to be nitric oxide (NO), may play an important part in the control of fetoplacental vascular tone. | | | To further explore this role we have determined the relaxation responses to exogenous NO and examined the temporal relationship between intracellular concentrations of cyclic GMP and vascular tone in isolated ring segments of human chorionic plate arteries. | | | Lastly, we have explored the relaxation responses to a wide range of agents known to elicit EDRF release in other vascular beds. |
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http://home.earthlink.net/~whitelin3/papers/1994a.html
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| | MSN Encarta - Search Results - endothelium-derived relaxing factor |
| | Muscle : relaxation of muscles : endothelium-derived relaxing factor: Furchgott, Robert F. Furchgottâs breakthrough studies with NO can be traced to the late 1970s, when he investigated the relaxation of smooth muscle in the blood vessels of... | | | Furchgott, Robert F., Ignarro, Louis J. Muscle : relaxation of muscles : endothelium-derived relaxing factor: Ignarro, Louis J. Ignarroâs research helped solve a mystery first uncovered in the late 1970s by American pharmacologist Robert F. Furchgott. | | | MSN Encarta - Search Results - endothelium-derived relaxing factor |
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http://encarta.msn.com/endothelium-derived+relaxing+factor.html
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| | University of Iowa Anesthesia Publications |
| | BACKGROUND AND PURPOSE: The predominant view is that the endothelium- derived relaxing factor generated by acetylcholine from blood vessels is nitric oxide. | | | However, there is evidence suggesting that certain nitric oxide-containing compounds such as nitrosothiols resemble the endothelium-derived relaxing factor generated by acetylcholine more closely than does nitric oxide itself. | | | CONCLUSIONS: S-Nitroso-L-cysteine resembles endothelium- derived relaxing factor from acetylcholine more closely than does nitric oxide. |
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http://www.anesth.uiowa.edu/readabstract.asp?PMID=0008248984
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| | Physiologic Effects of Anesthesic and Analgesic Agents |
| | Skeletal muscle relaxant effects are due to decreased transmission at the internuncial neuron in the spinal cord and not at the myoneural junction. | | | Muscle relaxation is not a feature and varying degrees of hypertonus and purposeful movement occur independent of surgical stimulation. | | | The limbic system endows information derived from internal and external events with its particular significance to the individual and thus determines purposeful behavior. |
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http://info.med.yale.edu/yarc/vcs/anesthesiaeffect.htm
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| | Referencias |
| | Hypercholesterolemia, atherosclerosis and release of endothelium-derived relaxing factor by aggregating platelets. | | | Shimokawa H, Flavahan NA, Vanhoutte PM: Natural course of the impairment of endothelium-dependent relaxations after balloon endothelial removal in porcine coronary arteries. | | | Rubanyi GM, Romero JC, Vanhoutte PM: Flow-induced release of endothelium-derived relaxing factor. |
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http://www.antioxidantes.com.ar/12/Ref00063.htm
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| | ll meccanismo attivo nella crescita dei capelli |
| | Endothelium-derived relaxing factor: identification as nitric oxide and role in the control of vascular tone and platelet function. | | | -Recent discoveries imply a role for the nitroxide free radical (NO) in the control of vascular tone, platelet function, and in the central nervous system.(1-2) The NO is apparently endothelium-derived relaxing factor, or EDRF,(1~2) an endogenous compound probably accounting for the action of nitrovasodilators such as nitroglycerin. | | | Endothelium-Derived Relaxing Factor and Minoxidil: Active Mechanisms in Hair Growth |
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http://www.anagen.net/m11.htm
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| | Anthony Gidari |
| | This was consistent with the knowledge that the superoxide ion is an inhibitor of the relaxation of aortic rings by nitric oxide, and that LY83583 inhibits nitric oxide-mediated relaxation of precontracted rings of aorta as effectively as it inhibits EDRF-induced relaxation. | | | These studies have employed various experimental preparations including rabbit aorta in tissue baths and cultured bovine aorta endothelial cells in order to study the formation and mechanism of action of endothelium-derived relaxing factor utilizing a number of different physiological and biochemical measurements. | | | Other studies, like the one described here, are being used to provide additional information about the identity, formation, and reactivity of EDRF. |
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http://www.hscbklyn.edu/http://2000Dorcas'Sites/pharmacology/gid.htm
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| | Atherosclerosiscc |
| | Although few studies have examined the effectiveness of massage therapy on atheroslerosis, massage has a relaxing effect and it has been shown to reduce stress-related hormone levels. | | | In addition, relaxation techniques may help individuals comply with habits necessary to reduce risk of atherosclerosis, such as dieting, quitting smoking, and exercising. | | | Nitrates—used to relax the vessels that supply the heart with blood; these medications reduce chest pain |
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http://www.besthealth.com/Integrated%20Medicine/ConsConditions/Atherosclerosiscc
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| | Olmos L et al / Acta Pharmacol Sin 2002 Nov; 23 (11): 967-973 |
| | Selective blockade of endothelium-dependent and glyceryl trinitrate-induced relaxation by hemoglobin and by methylene blue in the rabbit aorta. | | | The sustained level of relaxation induced by acetylcholine is taken as 100 %. | | | Phosphatidyl-serine-related adhesion of human erythrocytes to vascular endothelium. |
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http://www.chinaphar.com/qikanbj/aps/1671-4083/23/967.htm
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| | Science News: Atherosclerosis KOs anti-spasm fighter - endothelium-derived relaxing factor |
| | The most recent studies suggest that EFRF and atherosclerosis are linked in ways that could harm the patient. | | | If the endothelium is damaged, however, this three-step balance is lost and muscle fibers constrict. | | | He says atherosclerotic lesions inside the vessel walls impede EDRF production, and vessels tend to constrict and stop blood flow to tissues--with medical consequences that may be serious. |
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http://www.findarticles.com/p/articles/mi_m1200/is_n22_v132/ai_6199683
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| | Tramadol, buy tramadol, antibiotics, Weight Loss drugs, weight loss herbs, weight loss herbal formula, weight loss, ... |
| | P2u receptor-mediated release of endothelium-derived relaxing factor/nitric oxide and endothelium-derived hyperpolarizing factor from cerebrovascular endothelium in rats. | | | BACKGROUND AND PURPOSE: Stimulation of P2u purinoceptors by UTP on endothelium dilates the rat middle cerebral artery (MCA) through the release of endothelium-derived relaxing factor/nitric oxide (EDRF/NO) and an unknown relaxing factor. | | | CONCLUSIONS: Stimulation of P2u purinoceptors on the endothelium of the rat MCA released EDHF, in addition to EDRF/NO, and dilated the rat MCA by opening an atypical calcium-activated K channel. |
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http://auramon.com/ref-hemoglobin/hemoglobin-research-abs5.466.html
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| | Factor |
| | Endothelium-derived relaxing factor Endothelium-derived relaxing factor ( EDRF) was the tentative name of what was late... | | | Two factor theory Herzberg’s Two-Factor Theory was developed by Frederick Herzberg, an academic who concluded that at wo... | | | Factor analysis Factor analysis is a statistical technique that originated in mathematical psychology. |
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http://www.brainyencyclopedia.com/topics/factor.html
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| | [Frontiers in Bioscience, 3, e23-38, April 27, 98] |
| | A major vasorelaxant of endothelial origin is endothelium-derived relaxing factor (EDRF) which has been identified as nitric oxide (NO) (15,42). | | | Since Furchgott and Jawadzski demonstrated in 1980 that acetylcholine-evoked relaxation of blood vessels is dependent upon the presence of intact endothelium, it has become increasingly clear that the endothelium plays a major role in the control of regulation of vascular tone, growth, and adhesion | | | Endothelial dysfunction associated with aging and hypertension results in reduced production of NO in heart and large blood vessels (30,45,52,77,82). |
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http://www.bioscience.org/1998/V3/e/rahmani/4.htm
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| | Endothelium-derived relaxing factor - Wikipedia, the free encyclopedia |
| | The Nature of the Endothelium-Derived Relaxing Factor ( http://www.hscbklyn.edu/pharmacology/furch.htm) | | | Endothelium-derived relaxing factor ( EDRF) was the tentative name of what was later discovered to be | | | It causes the smooth muscle in the vessel wall to relax, resulting in vasodilation. |
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http://en.wikipedia.org/wiki/EDRF
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| | References |
| | Rapoport RM, Draznin MB, Murad F (1983) Endothelium-dependent relaxation in rat aorta may be mediated through cyclic GMP-dependent protein phosphorylation. | | | Forstermann U, Mugge A, Alheid U, Bode SM, Frolich JC (1989) Endothelium-derived relaxing factor (EDRF): a defence mechanism against platelet aggregation and vasospasm in human coronary arteries. | | | Callejas NA, Casado M, Bosca L, Martin-Sanz P (1999) Requirement of nuclear factor kappaB for the constitutive expression of nitric oxide synthase-2 and cyclooxygenase-2 in rat trophoblasts. |
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http://herkules.oulu.fi/isbn9514268512/html/b869.html
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| | Tramadol, buy tramadol, antibiotics, Weight Loss drugs, weight loss herbs, weight loss herbal formula, hair loss, hair ... |
| | Effects of microinjection of atrial natriuretic factor (ANF) into cardioinhibitory sites in the nucleus ambiguous (NA) or on single vagal cardioinhibitory neurons (VCN) were investigated in urethan-anesthetized rats. | | | Vasodilation following the infusion of acetylcholine is due to the release of endothelium-derived relaxing factor (EDRF). | | | Experiments were conducted on closed-chest, alpha-chloralose-anesthetized dogs with the heart paced at a constant rate. |
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http://darwinpharmacy.com/ref-propranolol/propranolol-research-abs3.67.html
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| | Patent 6,762,202 |
| | EDRF is a vascular relaxing factor secreted by the endothelium, and has been identified as nitric oxide (NO) or a closely related derivative thereof (Palmer et al, Nature, 327:524-526 (1987); Ignarro et al, Proc. | | | The specific ointment base to be used, as will be appreciated by those skilled in the art, is one that will provide for optimum drug delivery. | | | The precise dose to be used in the formulation will also depend on the route of administration, and the seriousness of the dysfunction or disorder, and should be decided by the physician and the patient's circumstances. |
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http://www.pharmcast.com/Patents100/Yr2004/July2004/071304/6762202_Infrared071304.htm
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| | Nutrition, Heart Disease & Stroke |
| | High blood levels of homocysteine is now considered to be a significant risk factor for stroke, heart attack, and reduced blood flow to fingers, toes and peripheral body parts. | | | A number of studies demonstrate that Coenzyme Q10 and Hawthorn supplementation can also be effective in reducing high blood pressure, presumably by helping to correct an underlying defect in the heartâs energetic system and relaxing blood vessel resistance to permit easier blood flow. | | | Safety of treatment, changes In risk factors, and incidence of coronary heart disease. |
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http://www.nutra-education.com/html/nutrition__heart_disease___str.html
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| | Endothelium-derived relaxing factor inhibition and the pressor response to norepinephrine in the pregnant rat -- Allen ... |
| | Endothelium-derived relaxing factor inhibition and the pressor response to norepinephrine in the pregnant rat | | | METHODS: Eleven pregnant (mean +/- standard error of the mean 18 +/- 1 days of gestation) and 11 virgin conscious, unrestrained Sprague-Dawley rats with long-term indwelling vascular catheters were studied. | | | OBJECTIVE: To determine whether endothelium-derived relaxing factor (EDRF) plays a role in the blunted pressor response to norepinephrine that is characteristic of normal pregnancy. |
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http://www.greenjournal.org/cgi/content/abstract/83/1/92
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| | Level III Cardiovascular Seminar |
| | not mediate the hyperpolarisation and relaxation to acetylcholine in the rat small | | | modulates endothelium-dependent relaxation of rat basilar artery via myo-endothelial | | | cells in the relaxation of arterial smooth muscle by acetyl choline. |
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http://www.qub.ac.uk/smrg/People/Academics/Mark/MarksTeaching/NOseminar.html
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| | Endothelium-derived relaxing factor - Wikipedia |
| | Endothelium-derived relaxing factor suchen â um nach Endothelium-derived relaxing factor zu suchen. | | | Falls Du diese Seite soeben erstellt hast, kann es sein, dass die Aktualisierung der Datenbank verzögert wurde. |
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http://de.wikipedia.org/wiki/Endothelium-derived_relaxing_factor
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| | Table of Contents |
| | Check boxes for keywords you'd like to include in your search. | | | subarachnoid hemorrhage, cyclic guanosine monophosphate, endothelium-derived relaxing factor, vasospasm, angiography, pig | | | The authors have investigated the hypothesis that loss of endothelium-derived relaxing factor (EDRF) activity contributes to cerebral vasospasm after subarachnoid hemorrhage. |
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http://www.thejns-net.org/jns/issues/v76n5/abs/n0760830_r.html
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| | Inhibition of human platelet reactivity by endothelium-derived relaxing factor from human umbilical vein endothelial ... |
| | Inhibition of human platelet reactivity by endothelium-derived relaxing factor from human umbilical vein endothelial cells in suspension: blockade of aggregation and secretion by an aspirin-insensitive mechanism -- Broekman et al. | | | To determine a role for endothelium-derived relaxing factor/nitric oxide | | | Articles by Broekman, M. Articles by Marcus, A. Inhibition of human platelet reactivity by endothelium-derived relaxing factor from human umbilical vein endothelial cells in suspension: blockade of aggregation and secretion by an aspirin-insensitive mechanism |
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http://www.bloodjournal.org/cgi/content/abstract/78/4/1033
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| | Patent 6,323,211 |
| | Nitric oxide (NO) and NO donors have been recognized as mediators of nonvascular smooth muscle relaxation. | | | In another aspect, the present invention provides methods of treating and/or preventing sexual dysfunctions and/or enhancing sexual responses in a patient in need thereof by administering to the patient a therapeutically effective amount of at least one.alpha.-adrenergic receptor antagonist, and at least one compound that elevates levels of endogenous nitric oxide or EDRF in vivo. | | | The present invention describes methods for preventing and treating sexual dysfunctions in patients by orally administering at least one.alpha.-adrenergic receptor antagonist and at least one compound that elevates endogenous nitric oxide or endothelium-derived relaxing factor in vivo. |
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http://www.pharmcast.com/Patents/Yr2001/Nov2001/112701/6323211_sexual112701.htm
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| | Depression - Herbal Remedies, Symptoms, Types and Natural Remedies |
| | This stimulation releases substances such as endothelium-derived relaxing factor and prostacyclin thereby acting as a vasodilator. | | | In 1997 the New York Institute for Medical Research’s study was published in the Journal for the American Medical Association. | | | The mental deterioration caused by Alzheimer's seems to be significantly delayed by GBE's ability to enhance brain function, along with normalizing receptors in the brain and increasing the rate of neurotransmitter production. |
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http://www.depressionremedy.com/ginkgobiloba/depression/herbalremedy/print.php
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