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| | Sidney Kimmel Cancer Center |
 | | New molecular techniques have yielded a battery of potential therapies for many diseases, but the clinical fruits of these methods have not been as abundant, in part because in vitro models used for screening often do not duplicate in vivo conditions. | | | This laboratory utilizes our newly developed genomic and proteomic techniques for in vitro and in vivo analysis of the vascular endothelium in health and disease. | | | Our most recent project focuses on angiogenesis and the endothelium in disease, especially cancer. |
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http://www.skcc.org/schnitzer.html
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| | Robert Furchgott |
| | After the discovery that relaxation by EDRF is associated with a rise in cGMP in the vascular smooth muscle, we found that photorelaxation of arterial smooth muscle (using near UV radiation) is also associated with a rise in cGMP, which precedes the relaxation. | | | Furchgott, R. F., and Zawadzki, J. The obligatory role of the endothelium in the relaxation of arterial smooth muscle by acetylcholine. | | | Furchgott, R. Role of endothelium in responses of vascular smooth muscle. |
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http://www.hscbklyn.edu/pharmacology/furch.htm
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| | The Cardiac Endothelium - Cardiovascular Physiology - MEDSTUDENTS |
| | The endocardium endothelium (EE) is one of the most primitive strucuture in the human heart. | | | In one sudy, performed in this dog model described above, bosentan (endothelin receptor antagonist) improved LVF in a short-term basis and this drug could be proved useful in humans patients with heart failure. | | | Conversely, one study showed that ACE inhibitors, by supressing ET secretion, improved coronary function and the stabilization of cardiac rhythm after ischemia in rat hearts, suggesting the use of ET receptors antagonists as an antiarrhythmic drug. |
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http://www.medstudents.com.br/basic/cardfs/cardfs6.htm
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| | Clinical Specular Microscopy: In Vivo Findings of Specular Microscopy |
| | This observation is consistent with the current concept of acute corneal hydrops, wherein stretching of the endothelium and Descemet's membrane is presumed to result ultimately in the rupture of both structures, allowing aqueous humor to enter the corneal stroma. | | | Other substances such as glass and stainless steel also produce endothelial damage on contact, but the natural crystalline lens of the eye appears to cause little or no damage when it is touched to the endothelium for short periods. | | | This procedure is more likely to injure the endothelium if Fuchs' dystrophy or similar dystrophic changes are present |
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http://www.bio-optics.com/articles/01/art0106.htm
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| | Indigo Carmine Inhibits Endothelium-Dependent and -Independent Vasodilation -- Chang et al. 27 (2): 228 -- Hypertension |
| | Time-control responses to histamine before, during, and after IC are shown in D. Data are expressed as percent relaxation of contractions elicited by EC of phenylephrine (10 | | | Time-control responses to ACh before, during, and after IC are shown in D. Data are expressed as percent relaxation of contractions elicited by EC of phenylephrine (10 | | | Time-control responses to SNP before, during, and after IC are shown in D. Data are expressed as percent relaxation of contractions elicited by EC of phenylephrine (5x10 |
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http://hyper.ahajournals.org/cgi/content/full/27/2/228
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| | Effect of exercise training on endothelium-derived nitric oxide function in humans -- Green et al. 561 (1): 1 -- The ... |
| | This systolic antegrade, diastolic retrograde flow pattern and its accompanying oscillatory shear stress on the endothelium may explain the paradoxical greater contribution of NO during cycling than handgrip exercise, despite the greater mean flow during handgrip exercise. | | | This difference in flow patterns may also resolve another conundrum in the literature, that exercise training studies involving localized handgrip training have not always produced significant improvement in NO bioactivity (Green et al. | | | effects on the vascular endothelium may therefore provide a |
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http://jp.physoc.org/cgi/content/full/561/1/1
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| | Taylor & Francis Journals: Welcome |
| | Endothelium is a multidisciplinary biomedical journal on endothelial cell research, dedicated to the rapid turnaround of signficant basic and clinical research on the endothelium, including: | | | Endothelial-derived biologically active factors involved in the regulation of vascular tone and structure in haemostasis, fibrinolysis, inflammation and immune responses | | | Interactions of endothelium with other cell types and extracellular matrix/basement membrane |
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http://www.tandf.co.uk/journals/titles/10623329.html
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| | Capillary Endothelium |
| | However, it has been recently observed that endothelium acts as a source of substances that can aid vascular smooth muscle in relaxation or contraction. | | | These substances may promote responses such as inflammation and blood clotting. | | | The first is continuous capillaries found in muscle, lung, fat, connective tissue, and the nervous system. |
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http://www.usc.edu/dept/biomed/bme403/Section_3/capillary_endothelium.html
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| | Properties of the endothelium |
| | The endothelium can adapt rapidly to changes in its environment. | | | The endothelium may become activated by cytokines and develop specialisation for emigration of lymphoid cells. | | | Endothelium may become activated by cytokines and express cell adhesion molecules for neutrophils. |
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http://greenfield.fortunecity.com/rattler/46/endothelium.htm
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| | Endothelium definition - Womens Health and Medical Information on MedicineNet.com |
| | Endothelium definition - Womens Health and Medical Information on MedicineNet.com | | | By contrast, the outside layer of cells that covers all the free, open surfaces of the body including the skin, and mucous membranes that communicate with the outside of the body is called the epithelium. | | | Endothelium: A layer of flat cells lining the closed internal spaces of the body such as the inside of blood vessels and lymphatic vessels (that convey the lymph, a milky fluid) and the heart. |
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http://www.medterms.com/script/main/art.asp?articlekey=3248
(231 words)
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| | Endothelium |
| | Endothelial cells secrete a number of mediators (factors) which may elicit biological responses by various signal-transduction mechanisms. | | | Such mediators are implicated in regulating the permeability of the endothelium and can promote chemotactic responses like inflammation and blood clotting. | | | The endothelium is involved in a network of interactions between cells, cellular factors, humoral factors and matrix components and endothelial malfunctions are the cause of a great variety of pathophysiological states. |
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http://www.chemie.tu-darmstadt.de/bt/Endothel.html
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| | Leung, Mol Vis 2000; 6:15-23. |
| | The retrocorneal fibrous membrane (RCFM), first described by Fuchs in 1901 [1], has been observed in various clinical conditions associated with disease and damage to the corneal endothelium [2-4]. | | | This pathological membrane consists of fibrous ECM and elongated cells that are responsible for the fibrillar phenotypes. | | | Since corneal endothelium was not present in the previous work [22], a direct comparison of the two studies may hamper the information obtained from these studies. |
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http://www.molvis.org/molvis/v6/a4
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| | endothelium - multiple sclerosis encyclopaedia |
| | Until quite recently the endothelium was thought to be an inert lining of the blood vessels but it is now becoming clear that endothelial cells play a number of essential and complex roles within the body. | | | Chemotaxis, leukocyte capture and their interaction with cytokines is extremely complex and a lot of research work is currently being done in this field. | | | The cells of the endothelium are called endothelial cells. |
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http://www.mult-sclerosis.org/endothelium.html
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| | Regulation of the vascular system by neural and endothelial mechanisms. Andrzej Loesch |
| | Contribution to vascular research My research is focused on the electron-immunocytochemical (ultrastructural) localisation of the vasoactive agents, their synthetic enzymes or receptors in vascular tissue in physiological and pathophysiological circumstances. | | | It is now apparent that vasoactive agents released from vascular endothelium as well as those from perivascular autonomic nerves (sympathetic, parasympathetic, sensorimotor or intramural) are involved in the local control of vascular tone and blood flow. | | | The Galleries display ultrastructural images: (1) the introduction and cerebral endothelium, (2) the localisation of endothelial vasoactive agents and P2 receptor, (3) injured vessels, platelets and leukocytes, and (4) the perivascular nerves. |
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http://www.homepages.ucl.ac.uk/~ucgaanl
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| | endothelium - OneLook Dictionary Search |
| | endothelium : The On-line Medical Dictionary [home, info] | | | endothelium, endothélium : Technical and Popular Medical Terms [home, info] | | | Phrases that include endothelium: endothelium derived relaxing factor, corneal endothelium, endothelium camerae anterioris, endothelium of anterior chamber, corneal endothelium modulation factor, more... |
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http://www.onelook.com/?w=endothelium
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| | Untitled Document |
| | It plays a critical role in the mechanics of blood flow, the regulation of coagulation, leukocyte adhesion, and vascular smooth muscle cell growth, and also serves as a barrier to the transvascular diffusion of liquids and solutes. | | | Comment on this page's content or view comments made by others! | | | For years the endothelium was thought of as an inert single layer of cells that passively allowing the passage of water and other small molecules across the vessel wall. |
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http://bme.virginia.edu/ley/endothelium.html
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| | endothelium - definition of endothelium by the Free Online Dictionary, Thesaurus and Encyclopedia. |
| | This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional. | | | endothelium - an epithelium of mesoblastic origin; a thin layer of flattened cells that lines the inside of some body cavities | | | endothelium - definition of endothelium by the Free Online Dictionary, Thesaurus and Encyclopedia. |
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http://www.thefreedictionary.com/endothelium
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| | Lääketieteellinen mikrobiologia - Lääketieteellinen tiedekunta - Turun yliopisto |
| | Salmi, M., Koskinen, K., Henttinen, T., Elima, K., Jalkanen, S. 2004: CLEVER-1 mediates lymphocyte transmigration through vascular and lymphatic endothelium. | | | [A] Niemelä, J., Henttinen, T., Yegutkin, GG., Airas, L., Kujari, A-M., Rajala, P., Jalkanen, S. 2004: IFN-�?� induced adenosine production on the endothelium: a mechanism mediated by CD73 (ecto-5'-nucleotidase) up-regulation. | | | Ann Clin Microbiol Antimicrob, 3:5; 1-6.[C] Jalkanen, S., Salmi, M. Lymphocyte interaction with microvascular endothelium In Encyclopedia of the Microvasculature (in press), Ed. |
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http://www.med.utu.fi/mikrobiologia/tutkimus/Julkaisut2004.html
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