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Topic: Dorsal root ganglion


  
 dorsal root
comprises the central branches of the dorsal root ganglion cells and connects to the gray matter of the spinal cord; each spinal nerve has one.
http://crisp.cit.nih.gov/Thesaurus/00002447.htm   (25 words)

  
 Theses uitgebreid
Dorsal rhizotomy for the relief of chronic pain.
Uematsu's technique of radiofrequency thermocoagulation of the dorsal root ganglion was considered to be a relatively simple technique that could relieve pain and preserve motor function and proprioception.
These changes were not observed in a dorsal root ganglion when the lesion was made adjacent to the dorsal root ganglion and viewed using the same technique and timespan.
http://www.fdg.unimaas.nl/anesthesiology/theses_uitgebreid.htm   (14766 words)

  
 Diabetes: Morphometry of dorsal root ganglion in chronic ... @ HighBeam Research
Earlier pathological studies on spinal roots (10) and dorsal root ganglion showing demyelination, vacuolar degeneration, and pigmentary changes (11) have been supported by recent pathophysiological studies supporting the sensory neuron as a target and, in particular, the mitochondrion as the most relevant organelle.
The changes and loss in neurons are associated with dramatic changes in both dorsal and ventral roots, including florid demyelination (11).
Published values range from 13,000 to 18,000 for rat L5 DRG neurons when high-resolution methods of quantitation are used.
http://highbeam.com/library/doc0.asp?DOCID=1G1:84209429&...   (3484 words)

  
 Journal of Bone and Joint Surgery: Dorsal root ganglion neurones with dichotomising afferent fibres to both the lumbar ...
Dorsal root ganglion neurones with dichotomising afferent fibres to both the lumbar disc and the groin skin: A possible neuronal mechanism underlying referred groin pain in lower lumbar disc diseases
Patients who have a symptomatic degenerative intervertebral disc sometimes report pain in the groin.1-3 The groin area is innervated by the genitofemoral or ilioinguinal nerves in rats and in man. In rats, these are terminal branches of L1 or L2 spinal nerves.
Journal of Bone and Joint Surgery: Dorsal root ganglion neurones with dichotomising afferent fibres to both the lumbar disc and the groin skin: A possible neuronal mechanism underlying referred groin pain in lower lumbar disc diseases
http://www.findarticles.com/p/articles/mi_qa3767/is_200305/ai_n9258272   (1231 words)

  
 Traction of the lumbar spine for radicular low back pain
Reduction in mechanical irritation from venous congestion around the DRG may be an explanation for the efficacy of a treatment technique such as traction.
If, the interaction between the DRG and peripheral SNS is responsible for these immune responses during inflammation, then a treatment technique like traction may aid in reducing constriction of the affected peripheral nerves.
However, in acute radicular pain it becomes apparent that the DRG is likely to regulate the excitability of the sensory nerve endings (Devor 1999).
http://www.acay.com.au/~mkrause/traction.htm   (5259 words)

  
 Morphogenic Role for Acetylcholinesterase in Axonal Outgrowth during Neural Development
Retardation of neuritic outgrowth and cytoskeletal changes accompany acetylcholinesterase inhibitor treatment in cultured rat dorsal root ganglion neurons.
Our studies using cultured DRG neurons show that AChE levels increase in parallel with neurite outgrowth and that this expression can be modulated in response to the type of substratum.
In the peripheral nervous system (PNS), AChE is transiently expressed by developing dorsal root ganglion (DRG) neurons (10-14) and later in their axons and growth cones in the spinal cord (15,16).
http://ehp.niehs.nih.gov/members/1999/Suppl-1/81-87bigbee/bigbee-full.html   (3929 words)

  
 Axon Regeneration
In the vivo experiments, the researchers used the dorsal columns of rats to study the regeneration of CNS axons.
In another set of 6 rats, saline was injected into the dorsal root ganglion 48 hours prior to the spinal cord lesion.
The rats that were treated with saline had little to no regeneration on the injured axons in the dorsal columns.
http://www.unr.nevada.edu/~chan2   (984 words)

  
 British Journal of Pharmacology - Local anaesthetics block hyperpolarization-activated inward current in rat small ...
MAYER M.L. and WESTBROOK G.L. (1983) A voltage-clamp analysis of inward (anomalous) rectification in mouse spinal sensory ganglion neurones.
The blockade of different types of voltage-gated Na channels during regional anaesthesia by local anaesthetics has been studied extensively and is of eminent importance for suppressing pain transmission in peripheral nerve, dorsal root ganglion neurones and dorsal horn neurones of the spinal cord.
The present experiments show that local anaesthetics block the hyperpolarization-activated inward current in spinal dorsal root ganglion neurones of young rats.
http://www.nature.com/bjp/journal/v139/n7/full/0705363a.html   (5313 words)

  
 Membrane Potential Oscillations in Dorsal Root Ganglion Neurons: Role in Normal Electrogenesis and Neuropathic Pain -- ...
However, the behavior of the DRG soma is often mirrored, at least in part, in the
for oscillatory behavior in particular subtypes of DRG
Rizzo MA, Kocsis JD, Waxman SG (1996) Mechanism of paraesthesiae and hyperaesthesiae: role of Na channel heterogeneity.
http://www.jneurosci.org/cgi/content/full/19/19/8589   (5454 words)

  
 Cisplatin-Induced Apoptosis in Rat Dorsal Root Ganglion Neurons Is Associated with Attempted Entry into the Cell Cycle ...
Braga (1994) Off-treatment course of cisplatin-induced dorsal root ganglia neuronopathy in rats.
Tredici (1995) An ultrastructural study of neuronal changes in dorsal root ganglia (DRG) of rats after chronic cisplatin administrations.
Nolan, and J.B. Cavanagh (1986) The effects of cisplatin on rat spinal ganglia: a study by light and electron microscopy and by morphometry.
http://www.jci.org/cgi/content/full/101/12/2842   (6589 words)

  
 The Arginine-Rich Hexapeptide R4W2 Is a Stereoselective Antagonist at the Vanilloid Receptor 1: A Ca2+ Imaging Study in ...
Greffrath W, Kirschstein T, Nawrath H and Treede RD (2001) Changes in cytosolic calcium in response to noxious heat and their relationship to vanilloid receptors in rat dorsal root ganglion neurons.
Cholewinski A, Burgess GM and Bevan S (1993) The role of calcium in capsaicin-induced desensitization in rat cultured dorsal root ganglion neurons.
We have demonstrated for the first time in native rat dorsal root ganglion neurons, which are the most important peripheral
http://jpet.aspetjournals.org/cgi/content/full/301/3/981   (4168 words)

  
 Peripheral Inflammation Sensitizes P2X Receptor-Mediated Responses in Rat Dorsal Root Ganglion Neurons -- Xu and Huang ...
Ogata N, Tatebayashi H (1993) Kinetic analysis of two types of Na channels in rat dorsal root ganglia.
Hamilton SG, Warburton J, Bhattacharjee A, Ward J, McMahon SB (2000) ATP in human skin elicits a dose-related pain response which is potentiated under conditions of hyperalgesia.
Peripheral Inflammation Sensitizes P2X Receptor-Mediated Responses in Rat Dorsal Root Ganglion Neurons
http://www.jneurosci.org/cgi/content/full/22/1/93   (6494 words)

  
 Reduction in Potassium Currents in Identified Cutaneous Afferent Dorsal Root Ganglion Neurons After Axotomy -- Everill ...
Lankford, K. Waxman, S. and Kocsis, J. Mechanisms of enhancement of neurite regeneration: rat DRG neurite arborization in vitro after a conditioning sciatic nerve lesion in vivo.
on changes in the relative distribution DRG Na currents in normal and axotomized neurons.
In contrast, changes in cutaneous afferent DRG neuronal
http://jn.physiology.org/cgi/content/full/82/2/700   (5768 words)

  
 Spinal
 the ventral and dorsal rootlets unite to form the spinal nerve.
 The nerve fibers enter the spinal cord through the dorsal root.
 Each spinal nerve divides into a ventral ramus and a dorsal ramus.
http://www.bonniemyer.com/Spinal.html   (2197 words)

  
 Rat Dorsal Root Ganglia Neurons - Cambrex
A ganglion is a group of nerve cells forming a nerve center, especially one located outside the brain or spinal cord.
One axon extends centrally toward the spinal cord; the other axon extends toward the skin or muscle.
Dorsal Root Ganglion, also called Spinal Ganglion, is the ganglion of the posterior root of each spinal segmental nerve, containing the cell bodies of the unipolar primary sensory neurons.
http://www.cambrex.com/prod.ratDRG   (259 words)

  
 ePrintsUQ - Involvement of the Dorsal Root Ganglion in Acute Experimental Allergic Encephalomyelitis in the Lewis Rat - ...
ePrintsUQ - Involvement of the Dorsal Root Ganglion in Acute Experimental Allergic Encephalomyelitis in the Lewis Rat - A Histological and Electrophysical Study
We conclude that lesions of the afferent pathway to the spinal cord do not contribute significantly to the disturbances of hindlimb motor function in Lewis rats with EAE.
Involvement of the Dorsal Root Ganglion in Acute Experimental Allergic Encephalomyelitis in the Lewis Rat - A Histological and Electrophysical Study
http://eprint.uq.edu.au/archive/00002294   (284 words)

  
 [No title]
Functional mapping of the dorsal horn of the rat spinal cord
Nagy, I., Rang, H.P.  (1999)  "Heat- and capsaicin-activated channels in cultured dorsal root ganglion neurons"   9th World Congress on Pain  Wiena, Austria  pp.
Mapping of the spinal somatosensory system by using in vitro spinal cord preparations
http://www1.imperial.ac.uk/med/people/i.nagy.html   (3146 words)

  
 Low-Threshold, Persistent Sodium Current in Rat Large Dorsal Root Ganglion Neurons in Culture -- Baker and Bostock 77 ...
The persistent Na current we have found in DRG neurons corresponds closely to this
Our data are therefore most consistent with the presence of a Na channel in about half of the large DRG neurons, different from
are well-described properties of Ca channels in neonatal rat DRG neurons (Fedulova et al.
http://jn.physiology.org/cgi/content/full/77/3/1503   (6323 words)

  
 Dorsal root ganglion - Wikipedia, the free encyclopedia
These neurons bring sensory information into the brain and spinal cord.
In anatomy and neurology, the dorsal root ganglion is a nodule on a dorsal root that contains cell bodies of afferent spinal nerve neurons.
You can see the axons growing out of the ganglion.
http://en.wikipedia.org/wiki/Dorsal_root_ganglion   (117 words)

  
 Single-channel Properties of Recombinant Acid-sensitive Ion Channels Formed by the Subunits ASIC2 and ASIC3 from Dorsal ...
A set of these channels is expressed in dorsal root
Blatz, A.L., and Magleby, K.L. Quantitative description of three modes of activity of fast chloride channels from rat skeletal muscle.
ganglion neurons where they may participate in the transduction
http://www.jgp.org/cgi/content/full/117/6/563   (5402 words)

  
 The expression and distribution of tau proteins and messenger RNA in rat dorsal root ganglion neurons during ...
Our objective was to characterize the distribution of tau isoforms in developing and mature dorsal root ganglia neurons and during axonal regeneration following sciatic nerve axotomy.
This differential distribution was observed in the cell body, dorsal roots and sciatic nerve axons.
These isoforms are still present in all dorsal root ganglion neurons in neonates, whereas high molecular weight tau isoforms are expressed in a subset of dorsal root ganglion neurons.
http://www.arclab.org/medlineupdates/abstract_7644032.html   (359 words)

  
 Energy Citations Database (ECD) - Energy and Energy-Related Bibliographic Citations
The critical period for peripheral specification of dorsal root ganglion neurons is related to the period of sensory neurogenesis
Energy Citations Database (ECD) Document #6213889 - The critical period for peripheral specification of dorsal root ganglion neurons is related to the period of sensory neurogenesis
Availability information may be found in the Availability, Publisher, Research Organization, Resource Relation and/or Author (affiliation information) fields and/or via the "Full-text Availability" link.
http://www.osti.gov/energycitations/product.biblio.jsp?osti_id=6213889   (124 words)

  
 Profile
Davidoff RA, Hackman JC, Aspects of spinal cord structure and reflex function, Neurologic Clinics, 9(3), 533-50, August 1991
Holohean AM, Hackman JC, Mechanisms Intrinsic to 5-HT2B Receptor-induced Potentiation of NMDA Receptor Responses in Frog Motoneurones.
Valeyev AY, Hackman JC, Holohean AM, Wood PM, Davidoff RA, Pentobarbital-activated Cl(-) channels in cultured adult and embryonic human DRG neurons, Brain Research.
http://myprofile.cos.com/hackmanj22   (937 words)

  
 ePrintsUQ - Vulnerability of the Dorsal Root Ganglion in Experimental Allergic Encephalomyelitis
The dorsal (posterior) root ganglion is a relatively neglected part of the nervous system from the clinical point of view.
These and other studies in experimental animals suggest that in man the DRG may be a preferential (but neglected) site of focal structural and functional abnormalities in inflammatory and also other neurological diseases.
The vulnerability of the DRG is due to a deficient blood-nerve barrier and possibly also to a susceptibility of the branch point of the ganglion neurone to demyelination-induced conduction block.
http://eprint.uq.edu.au/archive/00000725   (257 words)

  
 Dorsal Root Ganglion
You may see some yellow-brown pigmentation in the cytoplasm of some neurons.
In pseudounipolar neurons, one axon divides close to the cell body into two processes, one of which becomes a "functional dendrite" (although it actually is a myelinated axon).
The dorsal root ganglion is encapsulated in condensed C.T. that is continuous with the sheath of the peripheral nerves that enter and leave it.
http://www3.umdnj.edu/histsweb/lab8/lab8DRG.html   (590 words)

  
 dorsal root ganglion - definition of dorsal root ganglion by the Free Online Dictionary, Thesaurus and Encyclopedia.
This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional.
You may also use the word browser links:
dorsal root ganglion is not available in the general English dictionary and thesaurus.
http://www.thefreedictionary.com/dorsal+root+ganglion   (90 words)

  
 Paclitaxel induces nucleolar enlargement in dorsal root ganglion neurons in vivo reducing oxaliplatin toxicity
Neurotoxicity was assessed by L5 dorsal root ganglion morphometry and H-reflex-related sensory nerve conduction velocity.
Sensory nerve conduction velocity was reduced after oxaliplatin alone (P<0.05) but unchanged when paclitaxel was given before oxaliplatin.
To investigate this toxicity, 10-week-old female Wistar rats were given single intraperitoneal doses of paclitaxel and oxaliplatin, alone or in combination.
http://www.nature.com/bjc/journal/v88/n12/abs/6601012a.html   (317 words)

  
 ASIC3 [Amiloride-sensitive Cation Channel 3; TNaC1; Testis Sodium Channel 1; Dorsal Root Ganglion ASIC (DRASIC)] , ...
Optimal working concentration must be determined by the end user.
ASIC3 [Amiloride-sensitive Cation Channel 3; TNaC1; Testis Sodium Channel 1; Dorsal Root Ganglion ASIC (DRASIC)], control peptide for AB5678P : AG352
Amiloride-sensitive Cation Channel 3; TNaC1; Testis Sodium Channel 1; Dorsal Root Ganglion ASIC (DRASIC)
http://www.chemicon.com/Product/ProductDatasheet.asp?ProductItem=AG352   (117 words)

  
 HLS [ Nervous Tissue and Neuromuscular Junction, dorsal root ganglion] LOW MAG
Nervous Tissue and Neuromuscular Junction dorsal root ganglion
HLS [ Nervous Tissue and Neuromuscular Junction, dorsal root ganglion] LOW MAG
http://www.bu.edu/histology/p/04401ooa.htm   (20 words)

  
 Plexus Lesion Proximal to dorsal root ganglion
Brachial Plexus Lesion Proximal to dorsal root ganglion
http://www.eatonhand.com/clf/clf344.htm   (17 words)

  
 Second Messenger Modulation of Dorsal Root Ganglion Neurons
Second Messenger Modulation of Dorsal Root Ganglion Neurons
http://lifesci.rutgers.edu/~mplummer/lab/rldlec5/tsld009.htm   (16 words)

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