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| | Directly Observed Therapy Being Considered for HIV Infection |
 | | Directly Observed Therapy Being Considered for HIV Infection | | | Clinical trials should be designed with adequate follow-up to compare retention on therapy, virologic and immunologic outcomes, evaluation of the development of drug resistance, and cost-effectiveness analysis, the authors conclude. | | | The primary reason for considering DAART is the large role that inadequate medication adherence plays in virologic failure, Dr. Lucas' group notes in their review published in the November issue of AIDS Patient Care and STDs. |
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http://www.hivandhepatitis.com/recent/adh/010603e.html
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| | Directly Observed Therapy Effective in Difficult-to-Treat HIV-Positive IV Drug Users |
| | Methadone and antiretroviral drugs were dispensed daily and administered to patients as part of the directly observed therapy. | | | Triple therapy with nevirapine (NVP), didanosine (ddI), and stavudine (3TC) was given to most once-daily patients. | | | The majority of patients in the study achieved viral suppression to undetectable levels and the study data indicate DOT may be an appropriate method of combining addiction treatment with HIV therapy in these difficult-to-treat patients, he said. |
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http://www.docguide.com/dg.nsf/PrintPrint/9B91D14D6783188B85256B280065DD5E
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| | TB Policies: Directly observed therapy |
| | DOT is a method where every dose of anti-tuberculosis medications taken by the patient is directly observed and supervised by a health care worker or other responsible individual. | | | An individual who is being cared for by a non -NYCDOH physician may also receive DOT at a NYCDOH Chest Clinic, in which case the Physician-in-Charge must review the individual's medical regimen. | | | If an individual is not being treated under a program of DOT, the physician must document the reason in the individual's clinic medical record. |
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http://www.cpmc.columbia.edu/tbcpp/iv-dot.html
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| | American Thoracic Society Journal news tips for September 2004 (first issue) |
| | Directly observed therapy was defined as ingestion of anti-tuberculosis medications under the direct supervision of a health care worker. | | | When investigators compared tuberculosis (TB) patients who participated in directly observed therapy to patients with risk factors for non-adherence who performed self-administered therapy, they found that cure occurred in almost 98 percent of the patients treated by directly observed therapy as contrasted to a rate of slightly over 80 percent for the self-medicated patients. | | | The authors said that 44 percent of patients who receive self-administered therapy had risk factors and should have been assigned to directly observed therapy instead. |
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http://www.eurekalert.org/pub_releases/2004-09/ats-ats082604.php
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| | Doubts About DOT: Antiretroviral Therapy for Resource-Poor Countries |
| | DOTS is a multifaceted approach to TB therapy, including observed pill-taking, community and local government commitment, case detection by sputum smear microscopy, stable drug supply, and standardized systems for case follow-up. | | | The call for directly observed HIV therapy is rooted in experience with TB treatment. | | | While the public health advantages of directly observed HIV therapy are in question, the impact on individual freedoms is not. |
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http://www.aegis.com/news/ads/2003/AD031370.html
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| | TB News: Current News Article |
| | In response, Heymann, of the Harvard School of Public Health, and others note that directly observed therapy is not necessary for TB-incidence reduction, as evidenced by the decline in U.S. TB cases between 1953 and 1985, when the practice was not used. | | | With the development of effective antimicrobial therapy, sanatoria closed and the tuberculosis physician acquired a new body of knowledge and developed skills in pulmonary function testing, bronchoscopy, and, later, polysomnography. | | | Furthermore, the authors contend that directly observed treatment does not often use confinement to motivate patients to comply; rather, they point out that incentives and enablers are more commonly used. |
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http://www.hopkins-id.edu/tb_news/tb_news_11.html
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| | The Body: DOT for HAART: Directly Observed Therapy |
| | DOT programs are an effort to increase medication compliance to achieve better treatment successes. | | | DOT has been used to increase adherence with HIV medications in the prison setting. | | | DOT programs frequently consist of more than just observed therapy. |
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http://www.thebody.com/step/fall02/dot.html
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| | UCSF HIV experts question observed therapy in poor nations |
| | The editorial notes that DOT for tuberculosis therapy became a public health imperative to prevent emergence of drug resistance strains of TB and that the possibility of creating drug resistant strains of HIV is cited as a rationale for DOT for HIV. | | | The authors observe that there is no evidence yet that DOT is superior to self-administered therapy for reducing transmission through treatment, and if it were proved to be so, that the discussion of HIV DOT should not be limited to resource poor countries. | | | A team of HIV researchers at UCSF recommend against establishing directly observed therapy (DOT) as the model for the provision of HIV medications in resource poor countries. |
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http://www.eurekalert.org/pub_releases/2003-05/uoc--uhe052003.php
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| | APHA - Journal and Newspaper - American Journal of Public Health - Editorials July 1998 - Nihilism and Pragmatism in ... |
| | But directly observed therapy undermines public health nihilism wherever it improves TB outcomes through what is, after all, a modest and focused public health intervention. | | | Close scrutiny of settings in which directly observed therapy is held to be key to reversing unwelcome trends in TB control reveals it to have been merely one component of improved services. | | | In areas where therapy completion rates were already high, the impact of directly observed therapy was less impressive. |
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http://www.apha.org/Journal/editorials/ed3july.htm
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| | Directly Observed Antiretroviral Therapy for Injection Drug Users With HIV Infection |
| | Injection drug users (IDUs) who are in a methadone maintenance therapy program are required to attend their drug treatment clinic on a regular basis for directly observed therapy (DOT). | | | A prospective observational study was conducted to determine the efficacy of directly observed antiretroviral therapy provided in conjunction with daily observed methadone maintenance therapy. | | | Several studies have shown the efficacy of directly observed antituberculous therapy, |
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http://www.impactaids.org.uk/med1.htm
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| | CHEST: Utility of Rifampin blood levels in the treatment and follow-up of active pulmonary tuberculosis in patients who ... |
| | Patients with pulmonary TB who have been receiving appropriate antitubercular therapy for 3 months without clinical or chest radiographic (CXR) improvement and whose expectorated sputum continues to harbor Mycobacterium tuberculosis organisms are considered to be slow to respond. | | | During the study period, 124 new adult patients with non-drug-resistant pulmonary TB were started on a regimen of antitubercular therapy. | | | Patients continued to be followed up after completion of their antitubercular therapy to assess for relapse. |
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http://www.findarticles.com/cf_dls/m0984/5_120/80677285/p1/article.jhtml
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| | Directly Observed Therapy for HAART in an Urban US Setting |
| | Directly observed therapy (DOT) has been used with success in the treatment of tuberculosis; this intervention has been suggested and piloted as a method to improve ART adherence. | | | This study evaluates the feasibility of DOT for a subset of difficult-to-reach patients in whom unsupervised therapy for advanced HIV disease has failed. | | | Directly Observed Therapy for HAART in an Urban US Setting |
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http://www.natap.org/2004/HIV/050404_05.htm
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| | Canada's Role in the Fight Against Tuberculosis Today. |
| | The Directly Observed Therapy is the process whereby the ingestion of every dose of medication is directly observed. | | | Directly Observed Therapy (DOT) was started in 1990. | | | This method overcomes the problem of patients not taking their medicine as prescribed, which will lead to drug resistance. |
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http://collections.ic.gc.ca/tuberculosis/tbtoday/treatment/dot.html
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| | Directly observed therapy in HIV: A novel strategy to improve adherence in highly non-adherent HIV infected patients |
| | HAART therapy is life long, therefore the duration and setting for DOT has to be planned according to available resources and patient characteristics: longer in prison and clinic settings and shorter in case of skilled nursing facilities or other in-patient facilities. | | | Directly observed therapy in HIV: A novel strategy to improve adherence in highly non-adherent HIV infected patients | | | Directly Observed Therapy (DOT) has been proposed as a novel strategy to address adherence. |
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http://apha.confex.com/apha/131am/techprogram/paper_54415.htm
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| | HIV Report July 2001 - Directly Observed Therapy |
| | While DOT may ultimately play a part in the treatment of HIV, it seems likely that its role will be considerably more focused than the cornerstone position it assumes in TB treatment. | | | Adherence was 91% with the self-administered drugs and 86% with the directly observed drugs. | | | A considerable question left unanswered at the workshop was the long-term role of DOT in HIV therapy. |
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http://www.hopkins-aids.edu/publications/report/july01_7.html
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| | Making DOT Work |
| | DOT can take place in the office, clinic, or in the community and can be used alone or with other measures. | | | Success in DOT depends on an outreach worker's ability to problem solve, facilitate and empathize with his or her client. | | | Often the relationship that develops between the health care worker and the patient in the course of providing DOT contributes greatly to its success. |
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http://www.umdnj.edu/~ntbcweb/mdotw.htm
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| | The Body: Antiviral Potency and Tolerability of a Once-a-Day Directly Observed Therapy |
| | Furthermore, it helps to recall that many earlier studies of combination therapies excluded patients like those studied by Jayaweera because of the likelihood of treatment non-adherence; efforts like this study should be applauded for their attempts to evaluate and improve the care for some of the most difficult-to-treat persons in our communities. | | | Directly Observed Therapy (DOT) in HIV: Is it Feasible in Clinical Practice? | | | One way to improve adherence is to administer medications in a directly observed fashion (directly observed therapy, DOT), where medical professionals witness patients taking their medications. |
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http://www.thebody.com/confs/aids2002/young4.html
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| | Covered Tuberculosis-Related Services, Directly Observed Therapy and Directly Observed Preventative Therapy |
| | Directly Observed Therapy and Directly Observed Preventive Therapy | | | Reimbursement rates for directly observed therapy (DOT) and directly observed preventive therapy (DOPT) include necessary travel time and delivery of medications (if free delivery is unavailable). | | | Wisconsin Medicaid covers direct observation by a health care provider or other designated person as the recipient ingests TB medication. |
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http://www.dhfs.state.wi.us/medicaid5/handbooks/tb/covered_7.htm
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| | Directly Observed Therapy (D.O.T.) |
| | The Harlem Directly Observed Therapy (DOT) program, where patients are supervised while medication is administered, has been effective in controlling the spread of TB. | | | You can go to the chest clinic or a trained DOT worker can come to your home, your workplace, a park, or wherever you feel comfortable. | | | When this happens, a person with TB could get sick again, and the TB germs could become resistant to the medicines. |
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http://www.harlemtbcenter.org/dot_program.htm
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| | Directly observed therapy for treating tuberculosis (Cochrane Review) |
| | Patients allocated to directly observed therapy (DOT) compared had similar outcomes in relation to cure (Relative Risk (RR) 1.06; 95% confidence interval (CI) 0.98 to 1.14); and cure plus treatment completion (RR 1.06; 95% CI 1.00 to 1.13). | | | Directly observed therapy for treating tuberculosis (Cochrane Review) | | | The other study compared completion rates between participants who chose their DOT location and those receiving DOT at a community clinic and failed to demonstrate a significant difference (RR 0.88; 95% CI 0.63 to 1.23). |
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http://www.update-software.com/abstracts/ab003343.htm
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| | SD TB therapy |
| | Directly observed preventive therapy (DOPT) is a supervised course of therapy which is therapy provided to patients for treatment of latent TB (not active TB). | | | Directly observed therapy (DOT) is defined as “ a strategy devised to help patients adhere to treatment for active TB. | | | Physician or other health-care providers who believe their patient is in need of supervision of their therapy should contact the TB Control Program Coordinator at (605) 773-3737 or 1-800-592-1861 for a case conference to further discuss the case. |
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http://www.state.sd.us/doh/TB/therapy.htm
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| | Directly Observed Preventive Therapy For TB Pays Off |
| | The doctors found that DOPT increased the likelihood that individuals consumed all prescribed medication by roughly 60 percent compared with those in the standard therapy and peer groups. | | | "Improved adherence to preventive therapy means that tuberculosis will develop in fewer patients," says Chaisson. | | | Appearing in the June issue of the American Journal of Medicine, the study tested three approaches to providing isoniazid preventive therapy to three groups of injection drug users, 100 per group. |
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http://unisci.com/stories/20012/0529013.htm
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| | Aidsmap Latvian study reports good responses to individualised, directly observed therapy in patients with multidrug ... |
| | Once MDRTB was identified, the patient was hospitalised and treated as an inpatient with an individualised regimen based on the susceptibility tests until he or she became culture negative, after which point treatment was administered by direct observed therapy (with five to six visits a week) to ensure compliance. | | | Latvian study reports good responses to individualised, directly observed therapy in patients with multidrug resistant tuberculosis | | | The study, conducted in the Eastern European nation of Latvia, also demonstrated that it is possible for countries with somewhat limited resources to offer individualised therapy to manage MDRTB through their national TB programmes (NTPs). |
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http://www.aidsmap.com/en/news/7302825F-F1AC-445D-B8AF-A478358B090A.asp
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| | TB Policies: Preventive treatment |
| | The drug susceptibility pattern of the source case must be considered in the selection of the medications to be included in the preventive therapy regimen. | | | Two (2) anti-tuberculosis medications to which the source case's organism is susceptible should be used for preventive therapy. | | | The following individuals with a positive skin test are candidates for preventive therapy, regardless of age [3]. |
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http://www.cpmc.columbia.edu/tbcpp/iii-pxtx.html
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| | Catching Patients: Tuberculosis and Detention in the 1990s -- Lerner 115 (1): 236 -- Chest |
| | Burman, WJ, Cohn, DL, Rietmeijer, CA, et al (1997) Noncompliance with directly observed therapy for tuberculosis: epidemiology and effect on the outcome of treatment. | | | Weis, SE, Slocum, PC, Blais, FX, et al (1994) The effect of directly observed therapy on the rates of drug resistance and relapse in tuberculosis. | | | Nolan, CM (1997) Beyond directly observed therapy for tuberculosis [editorial]. |
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http://www.chestjournal.org/cgi/content/full/115/1/236
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| | Tramadol, buy tramadol, antibiotics, Weight Loss drugs, weight loss herbs, weight loss herbal formula, weight loss, ... |
| | Directly observed therapy (DOT) to enable completion of antituberculous therapy works. | | | These include directly observed preventive therapy (DOPT) programs, use of masks, improved ventilation in crowded settings such as homeless shelters, and ultraviolet light germicidal irradiation of upper room air in such locations. | | | Therefore, in addition to DOT other means of preventing tuberculosis spread should be encouraged. |
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http://auramon.com/ref-tuberculosis/tuberculosis-research-abs5.165.html
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| | TBDotPolicy |
| | The benefit of DOT lies in the assurance that TB patients will better adhere to a therapy regimen, curing them sooner, and minimizing the risk of developing drug resistance. | | | Policy and procedures for Directly Observed Therapy (DOT) and Directly Observed Preventive Therapy (DOPT) for TB treatment and the role of outreach workers | | | DOT is one of the services that should strongly be considered in the treatment or discharge plan for diseased TB patients. |
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http://www.dph.state.ct.us/bch/infectiousdise/tbdotpol.htm
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| | The Forum for Collaborative HIV Research |
| | Salvage Therapy II - Summary of the Forum Workshop | | | Salvage Therapy II - AIDS 2005, 19 :747-756 | | | Transfer of HIV Diagnostic and Monitoring Technologies into Resource-Poor Settings |
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http://www.hivforum.org
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| | Directly Observed Therapy and Treatment Adherence |
| | A review of 32 programs using directly observed therapy (DOT) for the treatment of tuberculosis (TB) suggests that policy makers may require a better understanding of the programs to make them succeed. | | | A comparison of inputs with the World Health Organization's (WHO's) short-course DOT program shows that DOT programs often consist of over five parts of the United Nations' recommended strategy. |
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http://www.aegis.com/news/ads/2000/AD000753.html
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| | Publications - Online Publications: Directly Observed Therapy (DOT) for Tuberculosis |
| | Adherence is also difficult for health care providers to measure (Sumartojo 1993). | | | Publications - Online Publications: Directly Observed Therapy (DOT) for Tuberculosis | | | The Tuberculosis Working Group of the Ministry of Health strongly supports the use of DOT and urges all Medical Officers of Health to work with local medical practitioners to ensure that DOT is offered to all patients who are likely to benefit from it. |
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http://www.moh.govt.nz/moh.nsf/49ba80c00757b8804c256673001d47d0/257b42d9ef210e62cc2569ec007cb62f?OpenDocument
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| | Directly Observed Therapy topic - Unified Search Environment |
| | Directly Observed Therapy topic - Unified Search Environment | | | A treatment method in which patients are under direct observation when they take their medication or receive their treatment. |
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http://www.use.hcn.com.au/subject.%60Directly%20Observed%20Therapy%60/home.html
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| | Directly observed therapy for treating tuberculosis |
| | Direct observation of people taking their antituberculous drugs is widely advocated and forms part of the World Health Organization's 'directly observed therapy, short course' (DOTS) strategy. | | | The objective of this article produced by the Cochrane Review is to compare policies of directly observed therapy with self treatment at home in people requiring treatment for clinically active tuberculosis, or requiring medication for prevention of active disease, on cure and/or treatment completion. | | | The article concludes that the effects of direct observation on cure or treatment completion were similar to those of self-administered treatment. |
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http://www.eldis.org/static/DOC11952.htm
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