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| | dihydrocodeine, guaifenesin, and pseudoephedrine of Augusta, Georgia |
 | | Dihydrocodeine, guaifenesin, and pseudoephedrine may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, sedatives (used to treat insomnia), pain relievers, anxiety medicines, and muscle relaxants. | | | Dihydrocodeine, guaifenesin, and pseudoephedrine may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), pain relievers, anxiety medicines, seizure medicines, and muscle relaxants. |
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http://www.universityhealth.org/16192.cfm
(1613 words)
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| | Single dose dihydrocodeine for acute postoperative pain |
| | Its structure and pharmacokinetics are similar to that of codeine and it is used for the treatment of postoperative pain or as an antitussive. | | | Insufficient evidence that single-dose dihydrocodeine is effective in relieving acute postoperative pain. | | | For a single dose of dihydrocodeine 30 mg in moderate to severe postoperative pain the NNT for at least 50% pain relief was 8.1 (95% confidence interval 4.1 to 540) when compared with placebo over a period of 4-6 hours. |
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http://www.cochrane.org/reviews/english/ab002760.html
(564 words)
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| | Dihydrocodeine in postoperative pain |
| | Its structure and pharmacokinetics are similar to codeine, and it is used for the treatment of postoperative pain and as an antitussive. | | | For each trial the mean TOTPAR or SPID values for dihydrocodeine and placebo groups were converted to the percent of maximum total pain relief based on the categorical pain scales (%maxTOTPAR or %maxSPID). | | | Patients should be offered a more effective analgesic in the treatment of postoperative pain. |
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http://www.jr2.ox.ac.uk/bandolier/booth/painpag/Acutrev/Analgesics/AP015.html
(371 words)
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| | [No title] |
| | He continued to experience pain during the treatment, so his family practitioner changed the treatment to dihydrocodeine 30 mg six hourly, which largely controlled the pain. | | | He continued to take the dihydrocodeine regularly for two more weeks, and the erection he had while taking sildenafil during this time detumesced immediately after orgasm. | | | He later sustained a minor soft tissue injury to his right shoulder, for which he was initially given non-steroidal anti-inflammatory drugs. |
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http://www.mult-sclerosis.org/news/Jul2002/ViagraAndDihydrocodeineCrossInteractions.html
(530 words)
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| | Dihydrocodeine - Patient UK |
| | Dihydrocodeine is used to treat severe pain and severe coughs. | | | Never give it to others even if their condition appears to be the same as yours. | | | Before taking any 'over-the-counter' medicines, check with your pharmacist which medicines are safe for you to take alongside Dihydrocodeine. |
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http://www.patient.co.uk/showdoc/30003102
(787 words)
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| | Dihydrocodeine and Vicodin |
| | The primary use of Dihydrocodeine is for pain relief but also has other uses. | | | Dosage should be strictly controlled under the supervision of a doctor, side effects are similar to those of codeine including drowsiness. | | | It is usually administered in its form after surgery to control moderate to severe pain. |
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http://www.buycodeine.net/dihydrocodeine-vicodin.htm
(200 words)
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| | Dihydrocodeine - Health Therapies / Treatments Shopping at dooyoo.co.uk |
| | Symptoms mimic that of heart attack and angina pectoris - pain in the chest radiating to the arms, jaw, neck, shoulder, nausea - so it is a painful condition. | | | It’s an ok painkiller and because of the degree of my pain I don’t find it enduces a euphoric state, which is a good thing because that’s what leads to the addiction of painkillers. | | | Advantage: initial pain relief, gives a good high |
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http://www.dooyoo.co.uk/health-therapies-treatments/dihydrocodeine
(300 words)
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| | Patient Experience |
| | After a severe reacurrence of my back problem I was prescribed the combination of voltarol and dihydrocodeine 30mg I found this had little effect on the pain and took it upon myself to take 4 tablets at a time instead of the 2. | | | i was put on dihydrocodeine for back problems and i have experienced more problems with the drug than my back. | | | I've been taking dihydrocodeine for some time to reduce the severity of painful hip joints. |
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http://www.patient.co.uk/comments/30003102
(2693 words)
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| | sixthseal.com: DF118 (Dihydrocodeine tartrate) |
| | Most literature seems to indicate that dihydrocodeine is two times more potent than codeine itself, but I've just not have the same experience. | | | Qualitatively, I find that 300 mg of codeine feels "stronger" than 210 mg of dihydrocodeine, but I need more experiences to comment, since I've developed a tolerance to these things from rather frequent use. | | | If I take 100mg of codeine phosphate with 1g of APAP, I get a lovely relaxed feeling within ten minutes. |
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http://www.sixthseal.com/000631.html
(7975 words)
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| | [No title] |
| | White capsule shaped tablets, the 60mg are marked DHC 60, the 90 mg are marked DHC 90 and the 120 mg are marked DHC 120 Clinical Particulars 4.1 Therapeutic Indications For the relief of severe pain in cancer and other chronic conditions. | | | Opioid analgesics should be avoided in those patients with raised intracranial pressure or head injury. | | | Dihydrocodeine should be used with caution in patients taking monoamine oxidase inhibitors. |
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http://www.btinternet.com/~little_willow/barricade/research/dihydrocodeine.txt
(583 words)
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| | Paramol Tablets Information and Sales |
| | You should confirm that it is correct for you as an individual, before you use it, by checking it with your own doctor or pharmacist. | | | Paracetamol acts as an analgesic (pain killer), and antipyretic (lowers body temperature); Dihydrocodeine tartrate is also a powerful analgesic | | | Paramol Tablets combines dihydrocodeine with tried and tested pain relief of paracetamol, giving you a powerful way to fight pain - information and sales from My Pharmacy UK Click here to see other |
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http://www.mypharmacy.co.uk/medicines/medicines/p/paramol/paramol_tablets.htm
(632 words)
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| | Pan American Laboratories - Product Information |
| | This combination product is contraindicated in patients with hypersensitivity to dihydrocodeine, codeine, acetaminophen, caffeine, or any of the inactive components listed above, or in any situation where opioids are contraindicated including significant respiratory depression (in unmonitored settings or in the absence of resuscitation equipment), acute or severe bronchial asthma or hypercapnia, and paralytic ileus. | | | PANLOR SS® tablets are indicated for the relief of moderate to moderately severe pain. | | | Dihydrocodeine, like all opioid analgesics, may cause hypotension in patients whose ability to maintain blood pressure has been compromised by a depleted blood volume or who receive concurrent therapy with drugs such as phenothiazines or other agents which compromise vasomotor tone. |
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http://www.panlor.com/panlorss_insert.shtml
(2257 words)
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| | Over-the-counter medicines and the potential for unwanted sleepiness (No.24) |
| | One paper that assessed performance, looked at the effect of 20mg dihydrocodeine by subcutaneous injection for the relief of tourniquet pain. | | | We found very little literature relating to the effect of dihydrocodeine on sedation and performance impairment. | | | Codeine and dihydrocodeine are morphine-like substances, and are classed as weak opioid agonists, as both their analgesic and unwanted effects are much less than those of morphine. |
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http://www.dft.gov.uk/stellent/groups/dft_rdsafety/documents/page/dft_rdsafety_026928-06.hcsp
(2148 words)
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| | Analgesics |
| | The best drug for nociceptive pain (ie pain carried by a peripheral nerve to the brain) in terminal care. | | | These mild opioids provide relief of moderate pain. | | | Dihydrocodeine shows a plateau effect at a dose of 30mg 4 to 6-hourly, with only marginal additional pain relief at 60mg but more risk of nausea. |
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http://www.wlhc.demon.co.uk/formulary/NS/analgesics.html
(525 words)
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| | PJ Online The Society: Statutory Committee (29 May 2004) |
| | This led to comprehensive therapy for both his addiction to dihydrocodeine and his health problems. | | | He had not consulted a doctor, but to relieve the pain he had begun taking dihydrocodeine tablets from the stock of the pharmacies. | | | He had, however, been frank and forthright with the committee, he had a set of supportive references and the medical reports on him were optimistic in their assessment. |
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http://www.pharmj.com/Editorial/20040529/society/statcomm.html
(1504 words)
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| | Advice to patients (49) Dihydrocodeine tablets |
| | Problems can occur if dihydrocodeine is taken with some other medicines. | | | Are you taking any other prescribed medicines or medicines you have bought? | | | Eating foods that contain plenty of fibre and drinking plenty of fluid will help prevent constipation. |
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http://www.pharmj.com/Editorial/advicetips/advice_dihydrocodeine.html
(133 words)
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| | aspirin/caffeine/dihydrocodeine, Eastern Carolina |
| | Tell your doctor about all medicines that you are taking, and do not take any medicine without first talking to your doctor. | | | Dihydrocodeine (related to codeine) is in a class of drugs called narcotic analgesics. | | | Dihydrocodeine may cause addiction and withdrawal symptoms as well as other harmful effects in an unborn baby. |
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http://www.uhseast.com/114743.cfm
(1430 words)
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| | MyGP Irish Health Information Website |
| | Breastfeeding mothers may want an analgesic (painkiller) to treat a headache or muscular pain. | | | There is no research on the effects of dihydrocodeine on breast fed babies. | | | Dihydrocodeine is not therefore recommended in breastfeeding mothers, although risks are likely to be similar to codeine. |
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http://www.mygp.ie/DesktopModules/Articles/ArticlesView.aspx?TabID=3606&ItemID=1488&mid=11262
(344 words)
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| | Dihydrocodeine vs placebo RCTs |
| | If remedicated patients were withdrawn and their PR set to zero for all further time points. | | | Single dose analysis: All adverse effects were mild and no patients withdrew as a result. | | | No serious adverse effects were reported and no patients withdrew as a result. |
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http://www.jr2.ox.ac.uk/bandolier/painres/dihydro/dhcplac.html
(374 words)
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| | UNODC - Bulletin on Narcotics - 1955 Issue 3 - 002 |
| | Oberst [2] investigated the urinary excretion in morphine addicts of the following derivatives of morphine: 3,6-dia-cetylmorphine (heroin), alpha-isomorphine, 3-methylmorphine (codeine), dihydroheterocodeine, dihydrocodeine, dihydroisocodeine and dihydrocodeine methyl ether. | | | Dihydrocodeine methyl ether was excreted only in the bound form. | | | Oxidation at the nitrogen atom with removal of the methyl group has been demonstrated by the administration of morphine having carbon 14 in the methyl group attached to the nitrogen to both rats [10] and human subjects [11]. |
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http://www.unodc.org/unodc/bulletin/bulletin_1955-01-01_3_page003.html
(4673 words)
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| | Controlled release dihydrocodeine composition - Patent 4834984 |
| | Patients were crossed over to the second study medication on a mg. | | | Incorporation in the matrix may be effected, for example, by | | | There is also evidence to suggest that the use of the present dosage forms leads to a reduced risk of drug addiction. |
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http://www.freepatentsonline.com/4834984.html
(2632 words)
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| | Narcotic Analgesics Metabolized by CYP2D6 |
| | Quinidine, however, did not reduce the analgesic response to experimentally induced pain following dihydrocodeine. | | | It would appear that dihydrocodeine or another metabolite that is not dependent on CYP2D6 has analgesic activity, but further studies in patients with pain are needed.5 Little information on the effect of CYP2D6 inhibitors on other codeine derivatives is available. | | | Although some of these medications have been utilized for many years, the appropriate use of analgesics requires knowledge of their risks, benefits, and potential drug interactions. |
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http://www.pharmacytimes.com/article.cfm?ID=2238
(679 words)
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| | UNODC - Bulletin on Narcotics - 1953 Issue 4 - 005 |
| | The transformations carried out with the isomeric pair, dihydrocodeine and dihydroisocodeine are summarized in chart II. | | | This evidence indicated that in dihydrocodeine (and therefore in codeine and in morphine), the hydroxyl group at C | | | Accordingly, dihydrocodeine (XIa) and dihydroisocodeine (XIb), respectively, were subjected to the conditions of the Hoffmann exhaustive methylation and degradation reaction, and the complex mixture of products resulting in each case was separated into a basic fraction (XXIa, XXIb, XXIIa, XXIIb) and a neutral fraction (XIXa, XIXb, XXa, XXb). |
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http://www.unodc.org/unodc/bulletin/bulletin_1953-01-01_4_page006.html
(4047 words)
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| | Pharmalatina.com |
| | Allegra is a seasonal allergy medicine that your doctor can prescribe if it is right for you. | | | Propecia (finasteride) is a medical breakthrough - the first pill that effectively treats male pattern hair loss on the vertex (at top of head) and an..... | | | Dihydrocodeine Dihydrocodeine (DHC) is a synthetic opioid analgesic developed in the early 1900s. |
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http://www.pharmalatina.com
(211 words)
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| | A Rapid, Nearly Quantitative Conversion of Codeine to Hydrocodone - [www.rhodium.ws] |
| | Considerable time was invested in the oxidation step, but the notorious acid-lability of the morphinan skeleton precluded the utilization of any of the alternative methods tested, therefore we focused our attention on streamlining or refining the reported Oppenauer method. | | | When about 20ml of benzene had been distilled, the apparatus was allowed to cool and the reaction flask was set up for reflux. | | | In our hands, the catalytic hydrogenation of codeine in dilute acetic acid to dihydrocodeine gave material that was rather gummy and not suitable for carrying on the oxidation step. |
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http://www.erowid.org/archive/rhodium/chemistry/hydrocodone.html
(828 words)
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| | Dr. Hale's Breastfeeding and Medications Forum: Panlor or Dihydrocodeine |
| | A mother with a four month old infant has been prescribed Panlor SS for pain relief following knee surgery. | | | Hale's Breastfeeding and Medications Forum: Panlor or Dihydrocodeine | | | Do you have any information on dihydrocodeine use in breastfeeding? |
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http://neonatal.ttuhsc.edu/discus/messages/39/2081.html?1086878308
(55 words)
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| | Patient letters on RLS symptoms and remedies- Page 31 |
| | (1) Do high doses of dihydrocodeine interact with Requip and stop it from working, and if so what else could be done to help me through? | | | Once you are the right dose of Requip, you should not need the narcotic medication, so you should be able to slowly wean yourself off it (at the dose you are taking, you may be somewhat addicted, so it would be better to gradually taper your dose). | | | Codeine or its cousin dihydrocodeine do not chemically interact in any way with Requip. |
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http://www.rlshelp.org/rlscomp31.htm
(15392 words)
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| | Buy fiorinal for you |
| | Fiorinal with Codeine, a strong narcotic pain reliever and muscle relaxant, is prescribed for Buy Fiorinal-Fiornal-Fiorinal Online To Buy Fiorinal Online,Please Click "link" [link] THIS MEDICINE IF YOU HAVE HAD A SEVERE ALLERGIC REACTION to codeine, hydrocodone, dihydrocodeine, Myserver.org Online Directory - fiorinal Buy Fiorinal With Codeine Here. | | | In Stock Now For Secure and Guaranteed Delivery. |
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http://buy-fiorinal.sbn.bz
(424 words)
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| | Dihydrocodeine - definition of Dihydrocodeine in Encyclopedia |
| | As with other opioids, tolerance and physical and psychological dependence develop with repeated dihydrocodeine use. | | | In the United Kingdom dihydrocodeine is a Class B drug - making it more dangerous than cannabis which is a class C drug. | | | It was developed in the early 1900s, and is similar in chemical structure and pharmaceutical behaviour to codeine, but is approximately twice as potent. |
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http://encyclopedia.laborlawtalk.com/Dihydrocodeine
(210 words)
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| | NEJM -- Effects of dihydrocodeine, alcohol, and caffeine on breathlessness and exercise tolerance in patients with ... |
| | Effects of dihydrocodeine, alcohol, and caffeine on breathlessness and exercise tolerance in patients with chronic obstructive lung disease and normal blood gases | | | NEJM -- Effects of dihydrocodeine, alcohol, and caffeine on breathlessness and exercise tolerance in patients with chronic obstructive lung disease and normal blood gases | | | We measured breathlessness and exercise tolerance in 12 patients with chronic airways obstruction, moderate or severe breathlessness, and low or normal arterial carbon dioxide tension, after the patients received dihydrocodeine, alcohol, caffeine, or placebo (through double-blind administration). |
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http://content.nejm.org/cgi/content/short/305/27/1611
(470 words)
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| | MEDNEMO.it - Il sito noprofit del Dott. Luigi Vicari |
| | The stomach contained negligible amounts of diphenhydramine, free dihydrocodeine and total dihydrocodeine (0.029, 0.018 and 0.024 mg, respectively); concentrations of these drugs in the femoral muscle were 0.270, 0.246 and 0.314 microg/g, respectively. | | | The concentrations of diphenhydramine, free dihydrocodeine and total dihydrocodeine in the femoral venous blood (1.89, 3.27 and 3.30 microg/ml, respectively) were much higher than those in blood from the right cardiac chambers (0.294, 0.237 and 0.240 microg/ml, respectively). | | | The cause of death was considered to be drowning due to a drug overdose and cold exposure. |
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http://www.mednemo.it/abstracts/avvelenamenti/2002/febbraio/190202pois.htm
(949 words)
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| | Int. J. of Clin. Pharmacology and Therapeutics, No. 3/2003 |
| | Global assessment of the results suggests that the fixed combination cinnarizine 20 mg/dimenhydrinate 40 mg exerts only a minor effect on vigilance, not significantly different from betahistine, which is commonly regarded as a non-sedating antivertiginous drug. | | | In the pain threshold model no effects were observed in either group. | | | The role of active metabolites in dihydrocodeine effects |
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http://www.dustri.com/ze/cp/33cp0303.htm
(1480 words)
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| | IngentaConnect Affinities of Dihydrocodeine and its Metabolites to Opioid Recept... |
| | The current study was conducted to evaluate the affinities of dihydrocodeine and its metabolites to | | | These results suggest that dihydromorphine and its 6-O-glucuronide may provide a relevant contribution to the pharmacological effects of dihydrocodeine. | | | About 7% of the caucasian population which are CYP2D6 poor metabolizers thus may experience therapeutic failure after standard doses. |
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http://www.ingentaconnect.com/content/mksg/pto/2002/00000091/00000002/art00003
(391 words)
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| | [No title] |
| | acceptable dihydrocodeine salts are prepared using a new, simpler and less demanding technological process that does not require any special manufacturing device for the granulation with a supply of heat energy and without any need of incorporating auxiliary materials influencing release of the therapeutic agent in the molten state. | | | After the mixture is cooled down, properly treated and compressed into tablets, the required course of release of the active substance from the therapeutic formulation prepared in the above-described manner is achieved. | | | The composition according to any of preceding claims characterized in that the active substance is dihydrocodeine and/or its pharmaceutically or therapeutically acceptable salts. |
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http://www.wipo.int/cgi-pct/guest/getbykey5?KEY=03/86365.031023&ELEMENT_SET=DECL
(1795 words)
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| | Dihydrocodeine at FindWolf |
| | A directory of UK health, disease, illness and related medical websites that provide patient information. | | | A source of information on dihydrocodeine (DHC), hydrocodone and oxycodone. | | | Includes facts, extraction guide, list of products containing codeine, information on side effects, addiction and tolerance. |
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http://findwolf.com/Dihydrocodeine
(191 words)
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| | sixthseal.com: Malaysia: 30 mg codeine and 10 mg dihydrocodeine in MALAYSIA for 60 cents each! |
| | Posted by: Edam at May 24, 2004 09:07 AM I suffer with chronic pain daily and was wondernig if I can purchase dihydrocodeine without a perscription> | | | There’s only 10 mg of dihydrocodeine to the whopping 500 mg of paracetamol, so ah
I think I might need to get some coffee filters next time I have a migraine and have some cold water handy. | | | Anyway, the other one they have contains 500 mg of paracetamol and the inferior dihydrocodeine tartrate, which I haven’t tried before. |
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http://www.sixthseal.com/000605.html
(1849 words)
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| | MedlinePlus Drug Information: Narcotic Analgesics and Acetaminophen (Systemic) |
| | There is no information about whether dihydrocodeine or oxycodone causes birth defects in animals.Too much use of a narcotic during pregnancy may cause the fetus to become dependent on the medicine. | | | This may lead to withdrawal side effects in the newborn baby. | | | Pentazocine and propoxyphene did not cause birth defects in animals. |
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http://www.nlm.nih.gov/medlineplus/druginfo/uspdi/202392.html
(2717 words)
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| | SOFT/TIAFT 98 - Automated Analysis of Controlled Drugs in Biological Samples |
| | Quantitation is based on peak area ratios of analyte to deuterated internal standards, from calibration curves in the range 0.25-5.0 µg/ml morphine, codeine and dihydrocodeine and 0.05-1.0 µg/ml 6-MAM for urine analysis and 0.05-1.0 µg/ml morphine, codeine and dihydrocodeine and 0.01-0.2 µg/ml 6-MAM for blood analysis. | | | Recoveries of morphine, codeine, dihydrocodeine and 6 -MAM from blood were 59%, 58%, 57% and 56%, respectively. | | | The method has been optimised and evaluated, with limits of detection of 0.05 µg/ml for the four drugs in both blood and urine, based on a signal-to-noise ratio of 3:1. |
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http://www.tiaft.org/tiaft98/fri/p/f_p_39.html
(310 words)
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| | worried about painkiller overdose [Archive] - Rap Basement Message Board |
| | Dihydrocodeine has been having little to no effect so I've switched to Ibuprofen.. | | | i have been prescribed amoxycillin (anti biotic) and painkiller dihydrocodeine | | | You should tell your doctor to prescribe you something more powerfull or at least switch to Dihydrocodeine Injections |
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http://www.d12world.com/board/archive/index.php/t-202586.html
(474 words)
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| | Codeine Information - Home |
| | There you will learn about its history and background, medical indications, precautions, possible interactions with other drugs, routes of administration and dosage, detailed information on its metabolism and mechanism of action in human body, effects, as well as some information on drug testing. | | | You can find out more about codeine, dihydrocodeine, oxycodone, hydrocodone, pholcodine by reading the Facts. | | | The Codeine Information is the largest and most comprehensive not-for-profit source of information on use and abuse of codeine (mainly), dihydrocodeine, hydrocodone, oxycodone, and pholcodine on the internet. |
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http://codeine.50g.com/home.html
(586 words)
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