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Topic: Dextromethorphan



  
 Dextromethorphan - Wikipedia, the free encyclopedia
Hours after dextromethorphan therapy, (in humans) the metabolites (+)-3-hydroxy-N-methylmorphinan, (+)-3-morphinan, and traces of the unchanged drug are detectable in the urine.
Since their introduction, preparations containing the over-the-counter drug dextramorphan have been used in a manner inconsistent with their labeling, often as a recreational drug or for spiritual experiences.
There exists, therefore, the potential of drug-drug interactions between dextromethorphan and concomitant medications.
http://en.wikipedia.org/wiki/Dextromethorphan   (722 words)

  
 News - Dextromethorphan Effective in Select Patients With Painful Diabetic Neuropathy
Among patients with DN in the efficacy trial, dextromethorphan reduced pain intensity by a mean of 33 percent from baseline, memantine reduced pain intensity by a mean of 17 percent, and lorazepam reduced pain intensity by a mean of 16 percent.
The proportions of subjects achieving greater than moderate pain relief were 68 percent with dextromethorphan, 47 percent with memantine, and 37 percent with lorazepam.
Among patients with PHN, mean reductions in pain intensity were six percent with dextromethorphan, two percent with memantine, and 0 percent with lorazepam.
http://www.docguide.com/news/content.nsf/news/8525697700573E1885256BB100693AFD   (585 words)

  
 Dermatology Update: Can dextromethorphan be used to treat repetitive itching and scratching in atopic dogs? - ...
Perhaps there is a place for a drug such as dextromethorphan in the treatment of atopy, but for now my recommendation is to focus on traditional antipruritic therapies and monitoring of underlying disease.
If there is a true benefit from dextromethorphan, it suggests that some central component to pruritus or at least to the repetitive behaviors that clients and veterinarians interpret as pruritus (e.g.
For example, dextromethorphan has been effective in treating crib-biting in horses.
http://www.vetmedpub.com/vetmed/article/articleDetail.jsp?id=142665&pageID=2   (454 words)

  
 Drug Information - myDNA
Brompheniramine, dextromethorphan, guaifenesin, and pseudoephedrine is used to treat cough and nasal congestion associated with allergies or the common cold.
Brompheniramine, dextromethorphan, guaifenesin, and pseudoephedrine may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, other antihistamines, pain relievers, anxiety medicines, seizure medicines, and muscle relaxants.
Your pharmacist has additional information about brompheniramine, dextromethorphan, guaifenesin, and pseudoephedrine written for health professionals that you may read.
http://www.mydna.com/resources/meds/leaflets/d04862A1.html   (1457 words)

  
 Dextromethorphan Potentiates the Antinociceptive Effects of Morphine and the delta -Opioid Agonist SNC80 in Squirrel ...
Mercandante S, Casuccio A and Genovese G (1998) Ineffectiveness of dextromethorphan in cancer pain.
This distinction between the effectiveness of dextromethorphan on acute pain versus sensitized responses to pain is also consistent
-aspartate-receptor antagonist dextromethorphan lacks analgesic effects in a human experimental ischemic pain model.
http://jpet.aspetjournals.org/cgi/content/full/300/2/435   (4413 words)

  
 MedlinePlus Drug Information: Dextromethorphan (Systemic)
This medicine is available without a prescription; however, your doctor may have special instructions on the proper use of this medicine for your medical condition.
When you are taking dextromethorphan it is especially important that your health care professional know if you are taking any of the following:
If you are taking this medicine without a prescription, carefully read and follow any precautions on the label.
http://www.nlm.nih.gov/medlineplus/druginfo/uspdi/202187.html   (1384 words)

  
 Dextromethorphan (PIM 179)
However it is commonly used for dextromethorphan overdose and is likely to be effective and safe.
Ingesting dextromethorphan during the first trimester demonstrated no association between the drug and malformations (Heinonen, 1989).
There is no information currently available on the effectiveness of forced diuresis, alkalinization, acidification, haemoperfusion, or dialysis for the treatment of dextromethorphan overdose.
http://www.inchem.org/documents/pims/pharm/pim179.htm   (4517 words)

  
 Guaifenesin and Dextromethorphan
Dextromethorphan affects the cough reflex in the brain.
If you have an allergy to guaifenesin, dextromethorphan, or any other part of the medicine.
Guaifenesin is used to help bring up phlegm, thin secretions, and make a cough productive.
http://www.umm.edu/altmed/ConsDrugs/GuaifenesinandDextromethorphancd.html   (498 words)

  
 Clinical Trial: Dextromethorphan to Treat Patients with Voice Spasms
In animal studies, the drug has blocked one of the reflexes in the larynx that may be associated with spasms in the laryngeal muscles.
During the double-blind randomized cross-over study, three groups will be included, 10 patients with adductor or abductor spasmodic dysphonia, 10 with muscular tension dysphonia and 10 with vocal tremor.
This study will examine how dextromethorphan, a drug that alters reflexes of the larynx (voice box), might change voice symptoms in people with voice disorders due to uncontrolled laryngeal muscle spasms.
http://www.clinicaltrials.gov/ct/show/NCT00055549   (1141 words)

  
 Clinical Trial: Dextromethorphan Versus Placebo for Neuropathic Pain
The study requires one visit to the NIH outpatient Pain Research Clinic, and consists of three 9-week treatment periods.
Clinical Trial: Dextromethorphan Versus Placebo for Neuropathic Pain
Competitive and non-competitive NMDA antagonists limit dynorphin A-induced rat hindlimb paralysis.
http://www.clinicaltrials.gov/ct/show/NCT00001344   (646 words)

  
 MedlinePlus Drug Information: Dextromethorphan
This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
tell your doctor and pharmacist if you are allergic to dextromethorphan or any other drugs.
Vicks® 44e® Pediatric Cough and Chest Congestion Relief containing Dextromethorphan Hydrobromide and Guaifenesin
http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a682492.html   (2058 words)

  
 Information on DXM Cough Medicine Abuse Prevent DXM Abuse
Recent research indicates that the abuse of DXM cough medicine is a greater problem than previously though.
Terms for using dextromethorphan include: Robo-tripping, and Skittling, among others.
Cough medicine also is sometimes abused in combination with other medications, alcohol and illegal drugs, which can increase the dangerous side effects.
http://www.drugfree.org/Parent/Resources/Cough_Medicine_Abuse   (897 words)

  
 Congressional Effort to Address Dextromethorphan Abuse Hailed by CHPA
CHPA, working in cooperation with the Partnership for a Drug-Free America, has developed a program to raise awareness about and prevent OTC cough medicine abuse.
"We applaud Congressman Upton and Congressman Larsen for their leadership on this issue," continued Suydam, "and offer our total support for this much-needed initiative." In addition to supporting this aggressive legislation against unfinished dextromethorphan, the nonprescription medicine industry has been proactive in preventing the intentional abuse of its over-the-counter (OTC) dextromethorphan-containing products.
Terms and conditions, including restrictions on redistribution, apply.
http://www.prnewswire.com/cgi-bin/stories.pl?ACCT=109&STORY=/www/story/05-04-2006/0004355180&EDATE=   (651 words)

  
 A randomized, controlled trial of high-dose dextromethorphan in facial neuralgias -- Gilron et al. 55 (7): 964 -- ...
and dextromethorphan reduce pain in certain neuropathic pain
dextromethorphan during the main trial, only one repeatedly
pain during dextromethorphan treatment than during placebo treatment.
http://www.neurology.org/cgi/content/abstract/55/7/964   (354 words)

  
 Novel Single-Point Plasma or Saliva Dextromethorphan Method for Determining CYP2D6 Activity -- Hu et al. 285 (3): 955 ...
suggested salivary analysis for determination of dextromethorphan metabolic phenotype.
each of 12 subjects received a 15 mg immediate-release dextromethorphan
in the multiple-dose study to increase the dextromethorphan and
http://jpet.aspetjournals.org/cgi/content/full/285/3/955   (3531 words)

  
 DDI: Dextromethorphan and Monamine Oxidase Inhibitors (MAOIs) - UK Drug Information Center
DDI: Dextromethorphan and Monamine Oxidase Inhibitors (MAOIs) - UK Drug Information Center
Hansten and Horn’s Drug Interactions: Analysis and Management.
Allow 14 days to elapse between the discontinuation of the MAOI and the initiation of therapy with dextromethorphan.
http://www.mc.uky.edu/Pharmacy/dic/DDI/DextromethorphanMAOIDDI.htm   (200 words)

  
 DXM (dextromethorphan) information by Narconon Arrowhead & ecstasy addiction .com
Because of this, interest in the drug is growing rapidly.
Read all the latest news on ecstasy and drug addiction:
Other potential health hazards are: dry mouth, loss of body fluid, dry itchy skin, blurred vision, cognitive alterations, delusions, nausea, abdominal pain, vomiting, irregular heartbeat, high blood pressure, numbness of fingers or toes, redness of face, headache, loss of consciousness and death.
http://www.ecstasyaddiction.com/other_dxm.html   (436 words)

  
 GASNet Anesthesiology: Premedication with Oral Dextromethorphan Reduces Postoperative Pain After Tonsillectomy
GASNet Anesthesiology: Premedication with Oral Dextromethorphan Reduces Postoperative Pain After Tonsillectomy
http://gasnet.med.yale.edu/sa/1998/06/02.php   (11 words)

  
 The Use of Dextromethorphan (Benylin, Robitussin) in Dogs and Cats
Use cautiously in animals with allergies because in humans dextromethorphan has been associated with histamine release.
Dextromethorphan is used to treat chronic, dry cough in dogs and cats, under the direction of a veterinarian.
The Use of Dextromethorphan (Benylin, Robitussin) in Dogs and Cats
http://www.peteducation.com/article.cfm?cls=0&cat=1469&articleid=1395   (570 words)

  
 AAN: Dextromethorphan/Quinidine Cocktail Arrests PBA-Linked Inappropriate Laughing/Crying Episodes in MS
The researchers had theorized that dextromethorphan might then be beneficial in PBA-associated emotional incontinence, which is embarrassing and socially debilitating for affected people, said Hillel Panitch, MD, professor of neurology, University of Vermont College of Medicine, and director, Multiple Sclerosis Center, Fletcher Allen Health Care, Burlington, New York, United States.
MIAMI, FL -- April 18, 2005 -- A combination agent consisting of dextromethorphan and quinidine (Neurodex) appears to reduce the disproportionate and often incongruous laughing and crying in patients with multiple sclerosis (MS) due to pseudobulbar affect (PBA).
In their double-blind, placebo-controlled study, they recruited 150 patients with MS attending 22 community and university-based centers.
http://www.pslgroup.com/dg/24c492.htm   (665 words)

  
 Dextromethorphan (Benylin DM®, Robitussin DM ® ) in Pregnancy and Breast Feeding
Martinez-Frias ML, Rodriguez-Pinilla E.Epidemiologic analysis of prenatal exposure to cough medicines containing dextromethorphan: no evidence of human teratogenicity.Teratology.
Aselton P, Jick H, Milunsky A et al: First-trimester drug use and congenital disorders.
Debus O and coworkers have urged caution in the use of dextromethorphan during pregnancy until long term neurodevelopmental studies have been conducted on the offspring of mothers who received
http://www.perinatology.com/exposures/Drugs/Dextromethorphan.htm   (430 words)

  
 Effect of Dextromethorphan, Diphenhydramine, and Placebo on Nocturnal Cough and Sleep Quality for Coughing Children and ...
Gadomski A, Horton L. The need for rational therapeutics in the use of cough and cold medicine in infants.
Cough may be the most bothersome symptom for children with upper
Acute dystonia in a child associated with therapeutic ingestion of a dextromethorphan containing cough and cold syrup.
http://pediatrics.aappublications.org/cgi/content/full/114/1/e85   (3338 words)

  
 Dissociative (DXM,ketamine,PCP) brain damage findings
which covers the dissociative drug dextromethorphan (DXM) in considerable detail.
I've been studying the brain for several years now, concentrating specifically on memory and congition, the limbic areas, and neuropharmacological agents that affect NDMA receptors.
If you currently use, have used, or plan to use, any dissociative (drug which blocks NMDA receptors or which is a dissociative anaesthetic), then you should read this document.
http://www.lycaeum.org/drugs/DXM/dissociative.brain.damage.html   (7429 words)

  
 Continuity Clinic Notebook: Should Codeine, Dextromethorphan or Hydrocodone be Prescribed?
Combination Medications: antihistamines, decongestants, expectorants, and antipyretics and codeine or dextromethorphan.
Even if one of these etiologies is found, codeine, dextromethorphan, hydrocodone are often prescribed to give symptomatic treatment to children.
Introduction: Pediatricians often feel that they need to prescribe something when a patient comes to the office.
http://www.mcg.edu/pediatrics/CCNotebook/chapter2/cough.htm   (383 words)

  
 Dextromethorphan in Pregnancy -- Debus et al. 120 (3): 1038 -- Chest
Kazis, A, Kimiskidis, V, Niopas, I (1996) Pharmacokinetics of dextromethorphan and dextrorphan in epileptic patients.
In our study, patients were never exposed to > 60 mg/d of dextromethorphan.
Schmitt, B, Netzer, R, Fanconi, S, et al (1994) Drug refractory epilepsy in brain damage: effect of dextromethorphan on EEG in four patients.
http://www.chestjournal.org/cgi/content/full/120/3/1038   (942 words)

  
 Erowid DXM (Dextromethorphan) Vault
2 Bellingham Men Did Die From The Drug Dextromethorphan - Komo4News (Seattle WA), Jun 24 2005
FDA Warns Against Abuse of Dextromethorphan - Medical News Today, May 22 2005
The dextromethorphan defense: dextromethorphan and the opioid screen
http://www.erowid.org/chemicals/dxm/dxm.shtml   (452 words)

  
 Dextromethorphan (Street Names: DXM, DM, CCC, Triple C, Candy, Robo, Velvet, Rojo)
Dextromethorphan hydrobromide (DXM HBr) is a cough suppressant found in more than 120 over-the-counter cold medications either alone or in combination with other drugs such as acetaminophen, antihistamines (e.g.
It has for some time been used as a cough suppressant and may be useful for pain treatment and protection against nerve cell damage.
Recent adverse event reports to the DEA have led to monitoring of the drug.
http://www.deadiversion.usdoj.gov/drugs_concern/dextro_m/dextro_m.htm   (762 words)

  
 WebMD Health - Drug Search results for Dextromethorphan,
Search for prescription and over-the-counter medications by brand or generic name, or by condition.
WebMD Health - Drug Search results for Dextromethorphan,
WebMD does not provide medical advice, diagnosis or treatment.
http://www.webmd.com/drugs/search.aspx?stype=DRUG&query=Dextromethorphan,   (31 words)

  
 Mindjack Magazine: I Want a New Drug
Dextromethorphan hydrobromide, also known as DXM and Dex, is in a drug class known as dissociatives, which is short for dissociative anesthetics.
These types of drugs work by disconnecting the brain sensory input from the body.
Dextromethorphan (dextro-meth-or-phan) is the active ingredient in many over-the-counter cough suppressants and formulas, and it is also a powerful dissociative and psychedelic drug.
http://www.mindjack.com/danr/dxm.html   (686 words)

  
 Dextromethorphan Adverse Reactions
Besides that, there are gastrointestinal symptoms and skin reactions.
The most immediate risk arising from dextromethorphan seems to be its sporadic abuse.
A few cases of addiction have been recorded.
http://www.infomed.org/100drugs/dextadre.html   (98 words)

  
 Dextromethorphan
At the doses recommended for treating coughs (1/6 to 1/3 ounce of medication, containing 15 mg to 30 mg dextromethorphan), the drug is safe and effective.
Dextromethorphan, a semisynthetic narcotic, is an ingredient found in any cold medicine with "DM" or "Tuss" in the title or name.
At much higher doses (4 or more ounces), dextromethorphan produces disassociative effects similar to those of PCP and ketamine.
http://www.streetdrugs.org/dxm.htm   (373 words)

  
 Dextromethorphan (DXM) CESAR
1 DEA, Drugs and Chemicals of Concern: Dextromethorphan.
Dextromethorphan (DXM) is a synthetic substance most commonly found in a variety of over-the-counter (OTC) medicines as an antitussive (cough suppressant) and expectorant (an agent that promotes the removal of mucus from the respiratory tract).
NIDA Research Report Series, "Hallucinogens and Dissociative Drugs."
http://www.cesar.umd.edu/cesar/drugs/dxm.asp   (959 words)

  
 Drugs and Human Performance FACT SHEETS - Dextromethorphan
At recreational doses, positive effects may include acute euphoria, elevated mood, dissociation of mind from body, creative dream-like experiences, and increased perceptual awareness.
Psychotropic effects of dextromethorphan are altered by the CYP2D6 polymorphism: a pilot study.
The drug manufacturer states that the combined preparation of promethazine and dextromethorphan may cause marked drowsiness or impair the mental and/or physical abilities required for the performance of potentially hazardous tasks, such as driving a vehicle.
http://www.nhtsa.dot.gov/people/injury/research/job185drugs/dextromethorphan.htm   (1087 words)

  
 Dextromethorphan definition - Medical Dictionary definitions of popular medical terms
Dextromethorphan (DXM) is chemically related to codeine and acts on the brain to suppress cough, but it does not have the pain relieving and addictive properties of codeine.
Dextromethorphan definition - Medical Dictionary definitions of popular medical terms
Dextromethorphan: An oral cough suppressant available in the US without a prescription but which is sometimes abused as a recreational drug.
http://www.medterms.com/script/main/art.asp?articlekey=33329   (345 words)

  
 Phencyclidine - Wikipedia, the free encyclopedia
Internationally, PCP is a Schedule I drug under the Convention on Psychotropic Substances.
Chemically and pharmacologically it is a member of the family of dissociative anesthetics, which also includes ketamine, tiletamine and high doses of dextromethorphan.
Although the primary psychoactive effects of the drug only last hours, total elimination from the body is prolonged, typically extending over weeks.
http://en.wikipedia.org/wiki/Phencyclidine   (1489 words)

  
 Dextromethorphan
Dextromethorphan is a cough suppressant used for short-term treatment of nonproductive
http://www.kroger.com/hn/Drug/Dextromethorphan.htm   (239 words)

  
 MAPS: dextromethorphan and hallucinations
The only real risk of damage is Olney's Legions, which have not been found with dextromethorphan, but are common with other drugs in the same category.
Right now it is legal, but if it is publisized too much and people do stupid things with it, it will become illegal/impossible to obtain.
Low doses of dextromethorphan are extremely similar to ecstacy, but many times more safe.
http://www.maps.org/pipermail/maps_forum/1999-September/002066.html   (291 words)

  
 Dextromethorphan Linked To Birth Defects
"Based on this, it can be predicted that the effects dextromethorphan had on the chicken embryos also would occur in human babies."
WESTPORT (Reuters) -- Dextromethorphan, an ingredient in some cough medicines, has been shown to cause birth defects and fetal death in chicken embryos exposed to concentrations relative to those typically taken by humans, according to a paper in the January issue of Pediatric Research.
According to Rosenquist, these findings add weight to recently reported findings from the Baltimore-Washington Infant Study in which a history of cough medicine use emerged as a risk factor for congenital malformations.
http://www.personalmd.com/news/a1998011510.shtml   (334 words)

  
 dextromethorphan - definition of dextromethorphan in the Medical dictionary - by the Free Online Medical Dictionary, ...
A drug that is used in its hydrobromide form as a cough suppressant and that is less addictive and has fewer side effects than codeine.
This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional.
dextromethorphan - definition of dextromethorphan in the Medical dictionary - by the Free Online Medical Dictionary, Thesaurus and Encyclopedia.
http://medical-dictionary.thefreedictionary.com/dextromethorphan   (96 words)

  
 Use of Codeine- and Dextromethorphan-Containing Cough Remedies in Children -- Committee on Drugs 99 (6): 918 -- ...
Adverse Reactions and Overdosage Acute overdosage of cough mixtures containing dextromethorphan has resulted in behavioral disturbances, including respiratory
of liver disease on dextromethorphan oxidation capacity and phenotype:
The drug, like codeine, acts on the central nervous
http://pediatrics.aappublications.org/cgi/content/full/99/6/918   (1420 words)

  
 DXM (dextromethorphan) and teen drug abuse information on MedicineNet.com
DXM (dextromethorphan) and teen drug abuse information on MedicineNet.com
The Food and Drug Administration (FDA) is concerned about the abuse of
Nearly half of OTC drugs, more than 125 products, contain an ingredient called dextromethorphan (or DXM).
http://www.medicinenet.com/script/main/art.asp?articlekey=47278   (822 words)

  
 Drug Abuse Alert for Dextromethorphan, Cincinnati Children's Hospital Medical Center
Most discovered the practice on the Internet or from friends at school.
Large doses of dextromethorphan may cause hallucinations, confusion, excitation, increased or decreased pupil size, nystagmus, seizures, coma and decreased breathing.
FalseFalseTrueTrue2/17/2000 7:39:00 PM1/1/30002-drugsDrug and Poison Information Center Issues Drug Abuse Alert Drug Abuse Alert for DextromethorphanThe Cincinnati Drug and Poison Information Center / DPIC at Cincinnati Children's Hospital Medical Center, noted an alarming drug abuse trend related to dextromethorphan.
http://www.cincinnatichildrens.org/about/news/release/2000/2-drugs.htm   (574 words)

  
 The Dextromethorphan FAQ
The bizarre truth about DXM is that it is a very potent psychoactive drug when taken in sufficient quantities.
Of course, dextromethorphan (DXM) does more than suppress coughs; otherwise, there wouldn't be so much discussion about it on alt.drugs (the Usenet newsgroup from which this FAQ originated).
This FAQ covers dextromethorphan (decks-tro-meth-OR-fan), the cough suppressant commonly found in cough medicines available over-the-counter in the USA and other parts of the world.
http://www.jasonsweb.com/Documents/Drugs/DXM/dxmfaq.htm   (1084 words)

  
 komo news 2 Bellingham Men Did Die From The Drug Dextromethorphan
2 Bellingham Men Did Die From The Drug Dextromethorphan
It was a pure, concentrated form of Dextromethorphan, also known as DEX or DXM.
Some of the material on this site contributed by the Associated Press.
http://www.komotv.com/stories/37621.htm   (551 words)

  
 WebMD with AOL Health - Patient Handout
Check the labels on all your medicines (e.g., cough-and-cold products) because they may contain drowsiness-causing ingredients, pain relievers/fever reducers (NSAIDs such as aspirin, ibuprofen, or naproxen) or the cough suppressant dextromethorphan.
Ask your pharmacist about the safe use of those products.
http://aolsvc.health.webmd.aol.com/drugs/mono-8095-SERTRALINE+-+ORAL.aspx?dr...   (1702 words)

  
 Acetaminophen, Dextromethorphan, and Pseudoephedrine
Dextromethorphan suppresses the cough center in the brain.
Pseudoephedrine shrinks swollen nasal tissue and opens up passages.
http://www.umm.edu/altmed/ConsDrugs/AcetaminophenDextromethorphanandPseudoephedrinecd.html   (566 words)

  
 Dextromethorphan Extraction
What follows is the procedure and effects of extracting Dextromethorphan Hydrobromide from OTC cough syrup.
A totally nonpolar solvent (e.g., naptha) is preferred, and can even be used with DXM plus guaifenesin syrups.
http://nepenthes.lycaeum.org/Drugs/DXM/extract.html   (986 words)

  
 DEXTROMETHORPHAN (DM) DOSAGE (COUGH SUPPRESSANT) - Lucile Packard Children's Hospital
DEXTROMETHORPHAN (DM) DOSAGE (COUGH SUPPRESSANT) - Lucile Packard Children's Hospital
· Dextromethorphan (DM) Dosage:  determine by finding your child's weight in the top row of the dosage table.
Lucile Packard Children's Hospital is located in Palo Alto, adjacent to Stanford University Hospital, approximately 20 miles north of San Jose, CA and 40 miles south of San Francisco.
http://www.lpch.org/HealthLibrary/ParentCareTopics/DrugDosageTables/DextromethorphanDMforcoughs.html   (104 words)

  
 Dextromethorphan
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 Buy Hold DM Dextromethorphan Cough Suppressant Lozenges, Original Online at drugstore.com
Buy Hold DM Dextromethorphan Cough Suppressant Lozenges, Original Online at drugstore.com
Active Ingredients: per lozenge: Dextromethorphan Hydrobromide 5mg (Antitussive)
http://www.drugstore.com/qxp11281_332828_sespider/hold_dm/dextromethorphan_cough_suppressant_lozenges_original.htm   (521 words)

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