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| | ADHD |
 | | Ritalin and dexamphetamine are gentle drugs as indicated by being licensed for use in young children. | | | The dopaminergic system is recognized as being involved in the experience of pleasure, and both electroconvulsive therapy and a number of dopamine facilitating drugs (e.g. | | | Clinical experience of Ritalin or dexamphetamine is that they are good anxiolytics. |
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http://www.althealth.co.uk/services/info/misc/adhd3.php
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| | Attract |
| | Dexamphetamine had a significant therapeutic response exceeding the placebo response (p = 0.045). | | | The response was similar in both genders and across the age range. | | | Given that stimulant medication use in adult ADHD appears to be long-term, studies of long-term efficacy need to be carried out". |
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http://www.attract.wales.nhs.uk/question_answers.cfm?question_id=1279
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| | Bozarth (ed., 1987): Assessing Drug Reinforcement, Chapter 11 |
| | This was conducted with dexamphetamine sulfate as the reinforcer at a dose of 0.015 mg/kg; 100 pairing trials were given on Day 2, and the test for conditioned reinforcement was on Day 6 rather than Day 3. | | | Evidence for primary reinforcement by doses of drug is later demonstrated by the behavior of a subject when the stimulus is presented contingent to lever-pressing responses. | | | The differences were the use of the intragastric route and a longer (10-hour) session for acquisition of self-administration behavior and in testing for conditioned reinforcement. |
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http://www.addictionscience.net/MARPADc11.htm
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| | NHMRC - Publications - |
| | Dexamphetamine and methylphenidate (Ritalin¨) act on dopaminergic and noradrenergic neurotransmitter pathways and appear to influence mainly prefrontal, frontal and limbic systems with benefits on disruptive behavioural inhibition, impulse control, selective attention, active working memory and executive functioning. | | | The stimulants are methylphenidate, which is most studied, and dexamphetamine, which is less so, and other medications are used (Werry 1994). | | | As Australian practice relies much more heavily than does the United States on the use of dexamphetamine rather than methylphenidate, the results of United States research into long-term effects of stimulant medication need to be supplemented by specific studies into the long-term use of dexamphetamine. |
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http://www.nhmrc.gov.au/publications/adhd/part2.htm
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| | Medication for Attention Deficit/Hyperactivity Disorder (ADHD): and analysis by Federal Electorate (200103) |
| | One of the concerns about ADHD in Australia is the growth in use of medication to treat the condition. | | | It has been suggested that one of the reasons for this disparity is a better understanding of ADHD among medical practitioners in Western Australia, although this is not a view that is universally accepted. | | | In 2001 Mackey and Kopras noted the wide disparity between the States and Territories in the number of prescriptions dispensed for dexamphetamine sulfate, highlighting in particular the disproportionately high number of prescriptions dispensed in Western Australia during 199900. |
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http://www.aph.gov.au/library/pubs/rb/2004-05/05rb02.htm
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| | eMJA: Serotonin toxicity with therapeutic doses of dexamphetamine and venlafaxine |
| | Dexamphetamine therapy was restarted three days later and citalopram therapy was commenced one week after discharge. | | | Increased awareness and cautious monitoring is advised when using a combination of dexamphetamine and either venlafaxine or an SSRI. | | | There is no theoretical reason why the interaction of citalopram (a pure SSRI) and dexamphetamine should cause catecholamine excess, and again the more likely explanation is serotonin toxicity. |
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http://www.mja.com.au/public/issues/176_05_040302/prior_letter_fm.html
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| | ADHD Articles and News |
| | The clinical evidence does not suggest the development of tolerance to the therapeutic effects [12]. | | | The open nature of this report is a serious limitation and makes it an unlikely basis to guide therapy [10]. | | | What the upper limit should be in clinical practice is difficult to decide in the absence of appropriate data. |
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http://www.addconsults.com/articles/full.php3?id=1037
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| | sixthseal.com: Incoming! 100 x 5 mg dexamphetamine tablets! =D |
| | When a patient is tolerating Ritalin or Dexamphetamine, they think he or she is getting more and more addicted. | | | Perhaps you may be ADHD yourself and this is why you are calmed, focused and able to sit still still when you take dexamphetamine in its medically prescribed does of 2 in the morning and 2 at lunch). | | | ADHD people taking dexamphetamine will be calmed and relaxed. |
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http://www.sixthseal.com/000512.html
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| | Restrictions on the Supply, Prescribing or Administration of Medicines under the Medicines Act 1991 |
| | Only medical practitioners vocationally registered under the Medical Practitioners Act 1995 in internal medicine, paediatrics, psychological medicine or psychiatry, or any medical practitioner acting on the recommendation of one of the above, may prescribe methylphenidate for a patient under his or her care. | | | Dexamphetamine can be dispensed at any community or hospital pharmacy. | | | Only medical practitioners vocationally registered under the Medical Practitioners Act 1995 in internal medicine, paediatrics, psychological medicine or psychiatry, or any medical practitioner acting on the recommendation of one of the above, can prescribe dexamphetamine sulphate for a patient under his or her care. |
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http://www.medsafe.govt.nz/Profs/RIss/restrict.htm
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| | Data Sheet |
| | In acute overdosage, the adverse effects are accentuated and may be accompanied by hyperpyrexia, mydriasis, hyperreflexia, chest pain, cardiac arrhythmias, confusion, panic states, aggressive behaviour, hallucinations, delirium, convulsions, respiratory depression, coma, circulatory collapse and death. | | | Use with caution in patients sensitive to amphetamines and other sympathomimetics. | | | Dexamphetamine is contra-indicated in patients with extrapyramidal disorders. |
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http://www.medsafe.govt.nz/Profs/Datasheet/d/Dexamphetaminesulphatetab.htm
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| | sixthseal.com: Upgraded dextroamphetamine sulfate (Dexamphetamine, Dexedrine) script...and a farewell |
| | Even though tolerance is a valid issue, this doctor has never prescribed dexamphetamine before (he told me the first time) and I have the feeling he may not be aware of tolerance issues. | | | It’s not common at all for controlled drugs like dexamphetamine to be prescribed in large amounts - the usual practice is to have time limited refills, not double the amount in one go (like what the doctor gave me today). | | | This worries me a bit though, I would like the site’s readers to read about my day, but I’m also aware that a doctor/medical insurance representative/pharmacist/law enforcement officer (*crosses fingers*) might stumble upon it and do something about it. |
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http://www.sixthseal.com/000540.html
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| | Crime and Misconduct Commission - Fighting crime / |
| | Clinical experience has shown that the most effective treatment for ADHD is a combination of medication (when necessary), therapy or counselling to learn coping skills, and ADD coaching for adults (Jaksa 1998). | | | Nonetheless, interested organisations must take a proactive approach if they wish to prevent ADHD drugs filling a void in the amphetamine market, especially in light of concerns that the widespread availability of prescription drugs is causing children to view drugs and drug-taking as normal. | | | The tendency to abuse stimulant drugs is clearly associated with the rave or dance scene (QCC 2001). |
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http://www.cmc.qld.gov.au/CRIMEBULLETIN4.html
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| | Louise Martinsson: Doktorsavhandling från Karolinska Institutet |
| | Safety of dexamphetamine in acute ischemic stroke: a randomized, double-blind, controlled dose-escalation trial. | | | Intensive early physiotherapy combined with dexamphetamine treatment in severe stroke: a randomized, controlled pilot study. | | | Facilitation of recovery after ischaemic stroke: Early dexamphetamine and physiotherapy treatment |
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http://diss.kib.ki.se/2003/91-7349-668-5
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| | Fed/ Australia falls short in ADHD drug treatment : Epilepsy.com |
| | Between 1999 and 2003, total prescriptions for dexamphetamine sulfate in Western Australia increased by more than 25,000, considerably higher than the rise of 2,527 prescriptions recorded in the second-ranked state, NSW, Mr Buckmaster said. | | | The use of drugs to treat ADHD remains controversial - the National Health and Medical Research Council recommends a multipronged approach combining medication, behaviour management and educational strategies. | | | It appears that Australia continues to have some distance to go before achieving best practice in the prescribing of medication for the treatment of ADHD. |
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http://www.epilepsy.com/newsfeed/pr_1101306608.html
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| | Tanveer Ahmed argues that ADHD is a sign of social degredation. - On Line Opinion - 24/9/2004 |
| | But while a host of reasons are given for the syndrome, from dodgy doctors to too much television, the role of desperate parents seeking a "product" to aid their parenting endeavours and, at times, absolve them of some responsibility, is less questioned. | | | Psychiatry has always been a mysterious and much-derided science, criticised by psychologists for being too focused on medication, looked down upon by other doctors for being too "wishy-washy", and often accused of being an arm of law and order rather than health and medicine. | | | Furthermore, it is hard for parents to take responsibility for difficult children. |
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http://www.onlineopinion.com.au/view.asp?article=2582
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| | [No title] |
| | Variables predicting a good outcome differed between oral and intravenous users; although for both groups being female was associated with a slower change in drug-use behaviours, but a longer period in treatment. | | | CONCLUSIONS: Dexamphetamine prescribing appears to be reasonably safe, and is associated with improvements in drug-use. | | | In the absence of more rigorous controlled trials, it was hoped that this study would help make some inroads into what is a hitherto unexplored area. |
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http://www.anakata.hack.se/papers/abstract/Addiction_2000_Feb-95-2-229-38.txt
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| | AM - Concern over level of 'kiddie speed' prescription |
| | The prescription of dexamphetamine, known as "kiddie speed", is increasing and Democrats Senator Lyn Allison says while the drug does solve an immediate problem, by calming children down, she's concerned so many children are being prescribed the drug. | | | ALEXANDRA KIRK: Senator Allison says she wants Australia to be part of a research program that can assess the impact of the drug, and help doctors and parents look at alternatives to drugs. | | | LYN ALLISON: We're seeing various studies being done around the world that are starting to question the growth of the use of this drug, and I think there's also a case to be made for other factors to be involved in attention deficit disorder, which is what this drug is used for. |
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http://www.abc.net.au/am/content/2004/s1086220.htm
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| | Dexamphetamine sulphate (PIM 178) |
| | There are differences between dexamphetamine and related compounds such as 3,4-methylenedeoxymetamphetamine ("ecstacy"); for example, hyperthermia appears to be more of a problem with the latter, and this may be because of the association between use and frenetic physical activity ("rave" dancing) (Henry et al., 1992). | | | Epigastric pain and haematemesis have been described after intravenous amphetamine use. | | | A case of ischaemic colitis with normal mesenteric arteriography in a patient taking dexamphetamine has been described (Beyer et al., 1991). |
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http://www.inchem.org/documents/pims/pharm/pim178.htm
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| | The World Today - WA crackdown on dexamphetamine |
| | But it's unfortunately the fact that even with the very best behavioural intervention we can have, medication is still working better. | | | DAVID HAY: There's been a very large American study that's shown in fact that medication is much, much, more effective than behavioural intervention. | | | In last years drugs have become available in America which are long lasting drugs. |
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http://www.abc.net.au/worldtoday/stories/s684652.htm
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| | Migrainepage Discussion Forum - "Dexamphetamine" |
| | Hi from what I can find out Dexamphetamine is used in treating ADHD and Narcolepsy. | | | I saw under another post that someone asked if they knew of any other newer types of drugs out there for migraines and someone said Dexamphetamine. | | | Questions or problems regarding this bulletin board should be directed to Webmaster |
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http://www.migrainepage.com/dcforum/discussion/8078.html
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| | Medication Therapy for ADHD |
| | The medication may be discontinued if there is no improvement at the end of four weeks and the other drug can then be trialed in a similar way. | | | However, no specific brain defect has been found that could account for ADHD, which also means there is probably no single drug that can correct the problem. | | | The two main stimulant drugs used in the treatment of ADHD symptoms include dexamphetamine and methylphenidate (Ritalin). |
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http://www.mental-health-matters.com/articles/print.php?artID=778
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| | Teknoscape Forums - WA top State for 'dexies' |
| | However, the medication is safe and effective when prescribed appropriately by a doctor to treat ADHD. | | | The package was developed by the Drug and Alcohol Office in collaboration with the school education drug project. | | | Dexamphetamine is used in the treatment of children with attention deficit and hyperactivity disorder but there is concern that it is getting increasingly into the hands of young people who do not have the condition. |
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http://www.teknoscape.com.au/forums/showthread.php?t=3840
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| | RACGP Managing ADHD In General Practice December - Complementary Medicine |
| | Method Patients previously stabilised on dexamphetamine were enrolled from a general practice. | | | Results Three of the four patients were clear responders to dexamphetamine (including a noncompleter, as his results still demonstrated a clear response). | | | Management was confirmed for three patients and changed for one (who ceased dexamphetamine). |
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http://www.racgp.org.au/document.asp?id=1094
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| | pregnancy.htm |
| | In a child who did not have ADD or ADHD, dexamphetamine could cause violent behavior. | | | He said a child's behavior could change quickly if medication wore off. | | | AMA senior psychiatrist Paul Skerritt said the effects of dexamphetamine or Ritalin were not long-lasting, which made it difficult to medicate schoolchildren. |
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http://www.parenting101.netfirms.com/news9.htm
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| | Differences in vulnerability and susceptibility to dexamphetamine in Nijmegen high and low responders to novelty: A ... |
| | Third, the behavioural responses to 2.0 mg/kg dexamphetamine did not differ between HR and LR. | | | It is concluded that knowledge acquired previously about the neurochemical differences between Nijmegen HR (APO-SUS) and Nijmegen LR (APO-UNSUS) rats can be used to analyse further the mechanisms of action underlying individual-specific differences in drug abuse in animals and man. | | | Susceptibility to behavioural effects of dexamphetamine (0.5-2.0 mg/kg. |
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http://www.nici.kun.nl/Publications/1997/11268.html
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| | Pelican 70-7, Page 22 |
| | It is presumed that passing through adolescence can be enough to balance serotonin and dopamine levels to allow an independence from the drugs. | | | In fact MDMA is thought to act serotagenically as well as dopaminogenically but has little utility for improving concentration. | | | Is it right to continue such a widespread prescription of these powerful, mood altering drugs? |
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http://www.pelican.guild.uwa.edu.au/editions/70-7/22.html
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| | Pilbara Division of General Practice |
| | The project has been developed by the Drug and Alcohol Office, in consultation with GPs, pharmacists and numerous professional medical bodies. | | | * General Practioners & Pharmacists Information: providing GPs and Pharmacists with a resource to help them in the education of parents whose children are prescribed dexamphetamine. | | | * Student Fact Sheet: providing students with information on dexamphetamine, the risks of illicit use and, for those prescribed dexamphetamine, the risks of supplying their medication to others. |
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http://www.pdgp.com.au/gpinfo.asp?ID=49
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| | Recommendations made by the PBAC - November 2004- Recommended restriction for modafinil |
| | therapy with dexamphetamine sulfate poses an unacceptable medical risk; or | | | Initial treatment, by a qualified sleep medicine practitioner, of patients with narcolepsy where: | | | intolerance to dexamphetamine sulfate of a severity necessitating permanent treatment withdrawal develops. |
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http://www.health.gov.au/internet/wcms/publishing.nsf/Content/pbacrec-nov04-modarest
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| | U.S. Medicine Information Central |
| | Other stimulants, such as caffeine, make pilots jittery and are not as effective at promoting alertness, he said. | | | Pilots "never really get enough to get to the point where some of the common side effects would really raise our heads," said Dr. Michaud. | | | Regarding the safety of dexamphetamine, Dr. Michaud emphasized that the drug is commonly prescribed to schoolchildren for Attention Deficit and Hyperactivity Disorder and is completely safe when used correctly. |
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http://www.usmedicine.com/article.cfm?articleID=587&issueID=47
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| | Michelle Maartensz work |
| | The medical profession is divided with regard to the drug's use for children. | | | Dexamphetamine is currently being used in various legitimate medical disorders or illnesses. | | | While the short term effects of Dex on children suffering this disorder are beneficial we do not know how they will be affected in the future by this medication. |
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http://www.newcastle.edu.au/discipline/fine-art/pubs/zine/nd2/michellegal.htm
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| | CNS Stimulants |
| | Dexamphetamine and methylphenidate have been advocated for the management of hyperactive children. | | | Patients with narcolepsy may derive benefit from treatment with dexamphetamine. | | | These include the amphetamines (notably dexamphetamine) and related drugs (e.g. |
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http://www.psychejam.com/cns_stimulants.htm
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| | eMJA: Licit psychostimulant consumption in Australia, 1984–2000: international and jurisdictional comparison |
| | This study is the first standardised analysis of drug consumption data from statutory international and national sources, and forms a reference for evaluating use of these drugs. | | | Results of large controlled studies have confirmed that psychostimulants are efficacious treatments in defined patients who are accurately diagnosed and whose treatment has been rigorously assessed. | | | PBS prescribing of dexamphetamine requires approval in States and Territories of patients and prescribers (usually psychiatrists and paediatricians). |
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http://www.mja.com.au/public/issues/177_10_181102/ber10505_fm.html
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| | Erowid Experience Vaults: Amphetamines - Dexamphetamine Sulphate - Dillusions |
| | Until now, I thought I was the only one on Earth mad enough to be addicted to something as horrible as Dexamphetamine. | | | Erowid Experience Vaults: Amphetamines - Dexamphetamine Sulphate - Dillusions | | | I would take them before having to do something I didn’t want to do. |
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http://www.erowid.org/experiences/exp.php?ID=34239
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| | [No title] |
| | There has been little research on side effects in a group using stimulant medication for the treatment of narcolepsy. | | | Dexamphetamine and methylphenidate are classified as addictive, but the frequency of addiction associated with medical use is unknown. | | | Tolerance refers to the need for an increased amount of medication to effect the same physiological response. |
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http://www.newcastle.edu.au/centre/nsdc/research.htm
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| | High 'kiddy speed' use pinpointed |
| | The study examines trends in the use of dexamphetamine and methylphenidate (Ritalin) in Australia and nine other countries from 1994 to 2000. | | | Australia and New Zealand are only behind the United States and Canada in their use of the drugs. | | | The Australian study also says high consumption of the drugs - known as "kiddy speed" - in Western Australia raises the possibility they are being misused. |
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http://www.nzdf.org.nz/update/messages/2014.htm
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| | Intermittent administration of dexamphetamine produces consecutive periods of sensitization and desensitization in ... |
| | Gingras, M.A.P.P., and Cools, A.R. Intermittent administration of dexamphetamine produces consecutive periods of sensitization and desensitization in rats: A study in Nijmegen high and low responders to novelty. | | | Intermittent administration of dexamphetamine produces consecutive periods of sensitization and desensitization in rats: A study in Nijmegen high and low responders to novelty | | | NICI > Publications > 1996 > Intermittent administration of dexamphetamine produces consecutive periods of sensitization and desensitization in rats: A study in Nijmegen high and low responders to novelty |
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http://www.nici.kun.nl/Publications/1996/9660.html
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| | Guideline 52 Section 5: Pharmacological therapy |
| | Cognitive and behavioural improvements included increased on-task behaviour; reduced fidgeting, finger tapping and interrupting; reduced impulsive responding and increased accuracy of performance; reduced aggression; improved compliance; improved parent child interactions; and increased peer status. | | | The initiation of pharmacological treatment for children with ADHD should only be undertaken by a specialist in either child and adolescent psychiatry or paediatrics who has training in the use and monitoring of psychotropic medications in children and adolescents. | | | MPH is presently licensed for patients aged six years and over. |
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http://www.sign.ac.uk/guidelines/fulltext/52/section5.html
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| | Drugs Misuse Research Initiative |
| | The project aims to assess the effectiveness of dexamphetamine | | | recognised best available treatment of amphetamine dependence; to describe the nature and extent of any benefits or harms to the mental or physical health of those receiving dexamphetamine; and to contribute to the development of guidelines for best practice in the management of amphetamine dependence. | | | Dexamphetamine Substitution as a Treatment of Amphetamine Dependence: A Two-Centre Randomised Controlled Trial. |
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http://www.mdx.ac.uk/www/drugsmisuse/treatment.html
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| | Medication Treatment in ADHD - A Guide for Educators |
| | Extensive research and clinical experience over decades demonstrate benefits of dexamphetamine or methylphenidate (Ritalin(R)) for: | | | There are no proven convincing general differences between the drugs, though individuals may respond better to one than the other. | | | Medication is started with either dexamphetamine or methylphenidate. |
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http://www.btinternet.com/~black.ice/addnet/medtreat.html
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| | Stimulants |
| | This might be augmented by the addition of medications like dexamphetamine, and/or disulfiram, and desipramine if depressed. | | | Since almost all crack cocaine abusers are cigarette smokers as well and since rapid smoking aversion therapy is the most effective stop smoking technique, I would think that rapid-smoking treatment of tobacco cigarettes by crack cocaine abusers in the presence of cocaine cues might be a useful form of therapy. | | | Dexamphetamine Sustained Release Helps in DB: A 128-patient 12-week DB PC study started with 15 or 30 mg and increased to 30 or 60 mg at 5 weeks. |
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http://www.modern-psychiatry.com/new_page_49.htm
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| | Dextroamphetamine - Wikipedia, the free encyclopedia |
| | Certain studies have been performed regarding possible alternate use for antidepressant treatment for HIV patients with depression and debilitating fatigue, early stage physiotherapy for severe stroke victims and treatment for those with methamphetamine (speed) addiction. | | | Possible adverse effects of dexamphetamine include insomnia, reduced appetite, dependence, nervousness, restlessness, irritability, and euphoria that may be followed by fatigue and depression. | | | There may be dryness of mouth, abdominal cramps, headache, dizziness, tremor, sweating, palpitations, increased or sometimes decreased blood pressure and altered libido. |
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http://en.wikipedia.org/wiki/Dextroamphetamine
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| | Drug Aware Drug Aware |
| | Dexamphetamine is used to treat Attention Deficit Hyperactivity Disorder (ADHD) and narcolepsy. | | | It is a stimulant drug, which increases the activity of certain chemicals in the brain. | | | Dexamphetamine is one of the most well known types of amphetamines. |
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http://www.drugaware.com.au/pages/dexamphetamines.asp
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| | Swinburne Centre for Neuropsychology: News |
| | Researchers investigating the effect of dexamphetamine, a commonly abused drug, on driving skill found performance decreased when the drug was present in a driver's system. | | | Taking dexamphetamine, commonly prescribed for attention deficit-hyperactivity disorder (ADHD) or the sleeping disorder narcolepsy, lowers your driving ability, Swinburne University of Technology researchers have found. | | | “Dexamphetamine can cause perceptual narrowing or ‘tunnel vision', which limits a driver's capacity to efficiently process information occurring in their peripheral vision, such as failing to stop at red traffic lights. |
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http://www.swin.edu.au/bioscieleceng/neuropsych/news.htm
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| | Swinburne Centre for Neuropsychology: Staff |
| | This study will also assess whether dexamphetamine reverses all the acute effects of sleep deprivation on performance and brain activity, and examine how well drivers perceive sleepiness and performance impairment when sleep deprived and using dexamphetamine. | | | Finally, this study will compared performance and brain function of dexamphetamine users with non-users to determine long term effects of dexamphetamine. | | | Description: This study is investigating mechanisms which might lead to accidents in professional drivers by evaluating neuropsychological and driving performance after 24 hours of acute sleep deprivation. |
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http://www.swin.edu.au/bioscieleceng/neuropsych/jackson.htm
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| | Australian Prescriber |
| | Data submitted by the manufacturer indicated that although this drug may be superior to dexamphetamine in some patients, the reverse is true in others, i.e. | | | A re-submission may include new data, new circumstances, new argument and new approaches to provide a basis for any change in the Committee's earlier decision. | | | As a consequence, the PBAC recommended that methylphenidate be listed at a price equivalent to that currently applying to the listing of dexamphetamine. |
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http://www.australianprescriber.com/index.php?content=/magazines/vol24no5/pbac.htm
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| | Queensland Children at Risk |
| | The use of psychostimulant medications, primarily dexamphetamine and methylphenidate (Ritalin), is a subject of great controversy. | | | Dexamphetamine and methylphenidate (Ritalin) are central nervous system stimulants listed in Schedule 8 of the Poisons List and subject to the requirements of the Poisons and Therapeutic Goods Act 1996. | | | John was born at 28 weeks gestation and had significant neo-natal health problems. |
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http://adhd-add.com.au/Queensland.htm
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