Depolarization - Medicow
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Topic: Depolarization



  
 Cardiac depolarization detection apparatus - Patent 4354497
A depolarization occurring at any area on the heart is first sensed by any one of the electrodes and then transmitted to a stimulation device which supplys stimulation pulses to the entire plurality of electrodes connected to the heart.
For example, a depolarization of ventricular tissue resulting from an impulse propogated from an ectopic focus may be sensed at a point adjacent the focus without there being a preceding depolarization within the interventricular septum.
If the conduction time grows longer, however, it may be that a naturally conducted depolarization could be sensed by one of the more remote electrode pairs 15-18, resulting in a false indication of an ectopic depolarization.
http://www.freepatentsonline.com/4354497.html   (4160 words)

  
 Activation of Elk-1, an Ets transcription factor, by glucose and EGF treatment of insulinoma cells -- Bernal-Mizrachi ...
A: Elk-1 phosphorylation is mediated by the ERK pathway.
elements is sufficient to mediate depolarization induction of
Results are representative of 2 independent experiments done in duplicate.
http://ajpendo.physiology.org/cgi/content/full/281/6/E1286   (7200 words)

  
 Sodium Influx Plays a Major Role in the Membrane Depolarization Induced by Oxygen and Glucose Deprivation in Rat ...
depolarize in association with an influx of Na
ionic channels are primarily responsible for this anoxic depolarization
in vivo work in the cortex in which some drugs that affect Na conductance could delay anoxic depolarization.
http://stroke.ahajournals.org/cgi/content/full/30/1/171   (5334 words)

  
 Mitochondrial membrane sensitivity to depolarization in acute myeloblastic leukemia is associated with spontaneous in ...
thiol oxidation in the depolarization and apoptosis pathways induced
Two of 10 samples were not sensitized with diamide, and the range of responses was large: +5% to +43% for mClCCP,
so we performed experiments using potassium chloride to depolarize
http://www.bloodjournal.org/cgi/content/full/98/2/405   (5732 words)

  
 Role of intracellular Ca2+ release in histamine-induced depolarization in rabbit middle cerebral artery -- Gokina and ...
Evidence for the role of nonselective cation channels in histamine-induced sustained depolarization.
In our experiments, application of caffeine initially resulted in a transient contraction and depolarization.
One of the unexpected and interesting observations of our study is that caffeine can induce a sustained depolarization of
http://ajpheart.physiology.org/cgi/content/full/278/6/H2105   (5736 words)

  
 Depolarization Stimulates Initial Calcitonin Gene-Related Peptide Expression by Embryonic Sensory Neurons In Vitro -- ...
The proportion of CGRP-IR neurons was quantified, and the data represent the mean and SEM of eight independent experiments.
To test that calcium was involved in increased CGRP expression under chronic depolarizing conditions, we visualized intracellular
7 by membrane depolarization through a Ca/calmodulin-dependent kinase pathway.
http://www.jneurosci.org/cgi/content/full/18/22/9294   (6119 words)

  
 Glucocorticoid-Induced Plasma Membrane Depolarization during Thymocyte Apoptosis: Association with Cell Shrinkage and ...
to define a role for Na -ATPase in the depolarization of
depolarization and suggests a potential role for Na
due to differences in the pathways that regulate depolarization
http://endo.endojournals.org/cgi/content/full/142/12/5059   (4531 words)

  
 Mechanisms of Spreading Depression and Hypoxic Spreading Depression-Like Depolarization -- Somjen 81 (3): 1065 -- ...
During the time indicated by the horizontal bar, a depolarizing stimulus of 0.2 nA was applied for 500 ms.
the onset of the depolarization can vary widely among individual
causing further depolarization (positive feedback), but it also lowers [Na o
http://physrev.physiology.org/cgi/content/full/81/3/1065   (9302 words)

  
 Plasma Membrane Depolarization Induced by Abscisic Acid in Arabidopsis Suspension Cells Involves Reduction of Proton ...
The depolarization observed in response to ABA could therefore
Representative results out of 10 individual experiments are shown.
Representative results out of 9 independent experiments are shown.
http://www.plantphysiol.org/cgi/content/full/135/1/231   (6856 words)

  
 Dissection of Mitochondrial Ca2+ Uptake and Release Fluxes In Situ after Depolarization-evoked [Ca2+]i Elevations in ...
response measured with low intracellular Na When pipette solutions contained no added Na, the recovery after depolarization lacked a plateau (left) and was not modified by CGP (1 µM, right).
Additional treatment with FCCP greatly modified the response (third response).
(E) Comparison between recoveries after weak (-35 mV, left) and strong (-10 mV, middle) depolarization elicited from another cell under voltage clamp using a Na -free pipette solution.
http://www.jgp.org/cgi/content/full/115/3/351   (7972 words)

  
 Neural Depolarization
This is an integrated healing therapy that is most effective when Neural Depolarization, Spiritual Tutoring and nutritional guidance are used together to facilitate the individual in their commitment to creating a healthy body, healthy mind and a healthy lifestyle.
Internal Spiritual Healing Therapies, including Neural Depolarization and Metaphysical Philosophy, as taught through Spiritual Tutoring, help us put prevention and healing of disease back into our own hands.
This therapy may also be used successfully in conjunction with other forms of medical treatment.
http://www.carolehoffman.com   (643 words)

  
 The Small G-protein Rac Mediates Depolarization-induced Superoxide Formation in Human Endothelial Cells -- Sohn et al. ...
is concluded that depolarization is an important stimulus of endothelial
the NAD(P)H oxidase inhibitor DPI, or this depolarization does
Consistent with the hypothesis of a pressure-induced depolarization,
http://www.jbc.org/cgi/content/full/275/25/18745   (3948 words)

  
 Mechanisms Underlying the Rapid Depolarization Produced by Deprivation of Oxygen and Glucose in Rat Hippocampal CA1 ...
The present study concerns the mechanism for generation, the site, and the ionic basis of the rapid depolarization of rat
further and approaches 0 mV (the persistent depolarization) (Rader
in stratum pyramidale was correlated with the rapid depolarization.
http://jn.physiology.org/cgi/content/full/78/2/891   (6574 words)

  
 Diabetes: Activation of nuclear factor-[kappa]B by depola... @ HighBeam Research
The relationships between [Ca.sup.2+]-activated pathways, their downstream targets, and the pleiotropic effects of depolarization have not been defined (7).
Glucose induces pleiotropic effects in islet [beta]-cells that are depolarization and [Ca.sup.2+] dependent, and these effects are potentially mediated by activation of multiple intracellular signaling pathways.
Interestingly, TNF-[alpha] treatment, unlike depolarization, activated this pathway in a MEK/ERK-independent fashion, suggesting that NF-[kappa]B dependent transcription in islet [beta]-cells can be induced by multiple pathways.
http://www.highbeam.com/library/doc0.asp?DOCID=1G1:95572159&refid=holomed_1   (3257 words)

  
 High K+-induced membrane depolarization attenuates endothelium-dependent pulmonary vasodilation -- Seiden et al. 278 ...
Data are expressed as means ± SE with no. of experiments shown in parentheses.
-mediated depolarization was characterized by an initial transient
to depolarize endothelial cells and affect endothelial function.
http://ajplung.physiology.org/cgi/content/full/278/2/L261   (3474 words)

  
 Regulation of eosinophil membrane depolarization during NADPH oxidase activation -- Bankers-Fulbright et al. 116 (15): ...
depolarize in response to various stimuli (Seligmann and Gallin,
After PMA stimulation, eosinophils rapidly depolarized to +17.3±1.8
Thus, eosinophil depolarization is predictably affected by changing proton
http://jcs.biologists.org/cgi/content/full/116/15/3221   (3395 words)

  
 Identifying Drug-Induced Changes in Electrocardiogram Results of Elderly Individuals
Common causes of artifact are muscle tremor, alternating current (AC) interference, loose electrodes, interference related to biotelemetry, and external chest compression.
The sinoatrial node, located at the junction of the superior vena cava and the right atrium, is the area of the heart which, under normal conditions, depolarizes most rapidly.
Depolarization spreads along the ventricular conduction system (the distal bundle branches and Purkinje fibers) first through the septum, then through the apex and into the bulk of the left and right ventricular walls.
http://www.ascp.com/public/pubs/tcp/1997/jan/idicerei.html   (2640 words)

  
 Neuroscience for Kids - Action Potential
If the neuron does not reach this critical threshold level, then no action potential will fire.
Remember, sodium has a positive charge, so the neuron becomes more positive and becomes depolarized.
This means that some event (a stimulus) causes the resting potential to move toward 0 mV.
http://faculty.washington.edu/chudler/ap.html   (767 words)

  
 Characterization of a Novel Calcium Response Element in the Glucagon Gene -- Fürstenau et al. 274 (9): 5851 -- ...
again that G2 is required for depolarization responsiveness of
C, effect of overexpression of the DNA-binding domain of NFATp (NFATpDBD) on depolarization responsiveness of the glucagon promoter.
Luciferase activity is expressed as percentage of the mean value in each experiment of the activity measured in the controls (unstimulated
http://www.jbc.org/cgi/content/full/274/9/5851   (6918 words)

  
 Depolarization-Induced Mitochondrial Ca Accumulation in Sympathetic Neurons: Spatial and Temporal Characteristics -- ...
responses elicited by such depolarizations, in contrast to
responses elicited by weak and strong depolarization and their sensitivity to FCCP in fura-2 AM-loaded sympathetic neurons.
that had not been depolarized or that were depolarized (50 K
http://www.jneurosci.org/cgi/content/full/19/15/6372   (7066 words)

  
 {beta}-Adrenergic Stimulation Modulates Ryanodine Receptor Ca2+ Release During Diastolic Depolarization to Accelerate ...
From the Laboratory of Cardiovascular Sciences, National Institute on Aging, Gerontology Research Center, Baltimore, Md.
depolarization might also be involved in the triggering of CRDDs
current during the diastolic depolarization, which, in turn,
http://circres.ahajournals.org/cgi/content/full/90/1/73   (4494 words)

  
 Sodium - Wikipedia, the free encyclopedia
Excitable cells, for example, rely on the entry of Na to cause a depolarization.
An example of this is signal transduction in the human central nervous system.
Sodium ions play a diverse role in many physiological processes.
http://en.wikipedia.org/wiki/Sodium   (941 words)

  
 Depolarization
This initial phase of the action potential is called the depolarization phase.
Now as the depolarization phase progresses, the status of the two physical forces that have been discussed changes.
At the end of the depolarization phase, the voltage of the inside of the axon relative to the outside is positive and the relative concentration of sodium ions inside the axon is greater than at the beginning of the action potential.
http://psych.hanover.edu/Krantz/neural/charge4.html   (199 words)

  
 Depolarization - definition of Depolarization in Encyclopedia
Depolarization of membrane potentials is important for other cell types, particularly muscle cells.
Depolarization typically results from the influx of positively charged ions (such as sodium or calcium) into the cell.
In neuroscience, depolarization refers to the event a neuron undergoes when its membrane potential grows more positive with respect to the extracellular solution.
http://encyclopedia.laborlawtalk.com/Depolarization   (82 words)

  
 Sustained Depolarization and ADP-Ribose Activate a Common Ionic Current in Rat Peritoneal Macrophages -- Campo et al. ...
Depolarization to +10 mV did not result in the development of any additional current.
This depolarization follows an increase in superoxide by a variable
Sustained Depolarization and ADP-Ribose Activate a Common Ionic Current in Rat Peritoneal Macrophages
http://www.jimmunol.org/cgi/content/full/170/3/1167   (4501 words)

  
 Atypical Ca2+-induced Ca2+ release from a sarco-endoplasmic reticulum Ca2+-ATPase 3-dependent Ca2+ pool in mouse ...
depolarization time on the induction of a TCP.
A TCP could be elicited only when the depolarization was long
immediately after the onset of the depolarization and escape
http://jp.physoc.org/cgi/content/full/559/1/141   (7608 words)

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