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| Â | MedlinePlus Drug Information: Daunorubicin |
 | | Daunorubicin has been used with other cancer- fighting drugs to treat the blastic phase of chronic myelogenous leukemia. | | | Talk to your doctor about the possible risks of using this drug for your condition. | | | This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. |
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http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a682289.html
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| Â | CancerBACUP : Daunorubicin |
| | If the sickness is not controlled, or continues, tell your doctor, who can prescribe other drugs, which may be more effective. | | | Changes in the way your heart works High doses of daunorubicin may cause changes in the muscle of the heart, which can affect how the heart works. | | | Tiredness and a general feeling of weakness It is important to allow yourself plenty of time to rest. |
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http://www.cancerbacup.org.uk/info/daunorubicin.htm
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| Â | MedlinePlus Drug Information: Daunorubicin (Systemic) |
| | Daunorubicin is sometimes given together with certain other medicines. | | | While you are being treated with daunorubicin, and after you stop treatment with it, do not have any immunizations (vaccinations) without your doctor's approval. | | | Daunorubicin is to be administered only by or under the immediate supervision of your doctor. |
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http://www.nlm.nih.gov/medlineplus/druginfo/uspdi/202183.html
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| Â | Daunorubicin: BC Cancer Agency |
| | Other drugs such as ciprofloxacin (Cipro®) may interact with daunorubicin. | | | Tell your doctor if you are taking this or any other drugs. | | | Check with your doctor or pharmacist before you start taking any new drugs. |
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http://www.bccancer.bc.ca/HPI/DrugDatabase/DrugIndexPt/Daunorubicin.htm
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| Â | Daunorubicin: BC Cancer Agency |
| | Daunorubicin should not be stored in contact with aluminium but it may be injected safely through an aluminium-hubbed needle. | | | Monitoring for cardiac toxicity should continue after daunorubicin therapy is complete. | | | USPDI: Drug Information For the Health Care Professional. |
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http://www.bccancer.bc.ca/HPI/DrugDatabase/DrugIndexPro/Daunorubicin.htm
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| Â | daunorubicin - [Medication] |
| | Your doctor will probably want you to have regularly scheduled blood tests and other medical evaluations during treatment with daunorubicin to monitor progress and side effects. | | | If for any reason an overdose of daunorubicin is suspected, seek emergency medical attention or contact your healthcare provider immediately. | | | Your doctor will determine the correct amount and frequency of treatment with daunorubicin depending upon the type of cancer being treated and other factors. |
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http://www.peacehealth.org/kbase/multum/d00205a1.htm
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| Â | ACS :: Cancer Drug Guide: daunorubicin |
| | Tell the nurse if you feel pain, burning, or discomfort in the vein when it is given. | | | Your doctor will test your heart function before you receive your first treatment, and then during the treatment. | | | Your doctor or nurse will give you specific instructions if your blood counts are low. |
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http://www.cancer.org/docroot/CDG/content/CDG_daunorubicin.html
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| Â | Emerging Trends in Management of Acute Myeloid Leukemia |
| | No significant differences in outcome were observed between the two therapeutic approaches, suggesting similar efficacy for daunorubicin and mitoxantrone. | | | To date, this is the only published investigation comparing daunorubicin and mitoxantrone for induction therapy in AML patients; no comparisons of idarubicin and mitoxantrone in this setting have been published. | | | Cytarabine plus idarubicin or daunorubicin as induction and consolidation therapy for previously untreated patients with acute myeloid leukemia. |
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http://www.meds.com/leukemia/trends/mon_pt1.html
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| Â | Intensifying Induction Therapy in Acute Myeloid Leukemia: Has a New Standard of Care Emerged? -- Rowe and Tallman 90 ... |
| | For much of the past two decades, induction therapy has consisted of daunorubicin, cytarabine, and 6-thioguanine (DAT). | | | Weick JK, Kopecky TJ, Appelbaum FR, Head DR, Kingsbury LL, Balcerzak SP, Ickers JN, Hynes HE, Welborn JL, Simon SR, Grever M: A randomized investigation of high-dose versus standard-dose cytosine arabinoside with daunorubicin in patients with previosly untreated acute myeloid leukemia: A Southwest Oncology Group study. | | | Several studies have explored the benefits of amsacrine, |
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http://www.bloodjournal.org/cgi/content/full/90/6/2121
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| Â | DAUNORUBICIN CITRATE LIPOSOME - INJECTION |
| | Tell your doctor if you have liver problems, heart problems, or have had chest x-rays. | | | Consult your healthcare professional before using this drug. | | | Daunorubicin can cause a reaction during the time the drug is being administered. |
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http://www.personalmd.com/drgdb/5327.htm
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| Â | Crystal structure of a ternary complex of DnrK, a methyltransferase in daunorubicin biosynthesis, with bound products ... |
| | One of the final steps in the biosynthesis of the widely used anti-tumor drug daunorubicin in Streptomyces peucetius is the methylation of the 4-hydroxyl group of the tetracyclic ring system. | | | Crystal structure of a ternary complex of DnrK, a methyltransferase in daunorubicin biosynthesis, with bound products -- Jansson et al., 10.1074/jbc.M407081200 -- Journal of Biological Chemistry | | | Crystal structure of a ternary complex of DnrK, a methyltransferase in daunorubicin biosynthesis, with bound products |
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http://www.jbc.org/cgi/content/abstract/M407081200v1
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| Â | Acute Myeloid Leukemia (Adult) - Symptoms, Treatment and Prevention |
| | Maintenance treatment is more associated with the treatment of ALL (Acute Lymphoblastic Leukemia) than AML (Acute Myelogenous Leukemia). | | | Standard treatment for acute myeloid leukemia includes two drugs: Daunomycin (daunorubicin) and Cytosar (cytosine arabinoside). | | | These drugs may cause significant nausea and vomiting, so patients are also given drugs such as Benadryl, Compazine, Vistaril, Reglan, and Ativan. |
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http://www.healthscout.com/ency/1/640/main.html
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| Â | HealthCentral - General Encyclopedia - daunorubicin hydrochloride |
| | Daunorubicin in the treatment of acute nonlymphocytic leukemia and acute lymphocytic leukemia. | | | Daunorubicin is often given in combination with other medications. | | | Unfortunately, it also interferes with normal cell growth and as a result may cause problems for the person taking this medication. |
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http://www.healthcentral.com/mhc/top/001755.cfm
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| Â | Daunorubinn |
| | Daunorubicin is one of the older chemotherapy drugs, which has been in use for many years. | | | This decision is made by the medical oncologist. | | | Daunorubicin, when prepared for use, becomes a clear, red liquid, and is given by intravenous route only. |
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http://www.tirgan.com/daunor.htm
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| Â | Daunorubicin Dosage, Interactions, Side Effects, How to Use |
| | This regimen is continued until there is progression of the disease or other complications of HIV disease preclude continued therapy. | | | Daunorubicin Dosage, Interactions, Side Effects, How to Use | | | The liposomal preparation helps protect daunorubicin from chemical and enzymatic breakdown; also, it minimizes protein binding and decreases uptake by normal tissues. |
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http://www.healthdigest.org/drugs/daunorubicin.html
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| Â | Coenzyme Q10 |
| | Coenzyme Q10 may help to reduce the toxic effects on the heart of daunorubicin and doxorubicin, two chemotherapy medications that are commonly used to treat a variety of cancers. | | | Consult your healthcare provider before using coenzyme Q10 supplements while you are taking these medications. |
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http://www.joannesway.com/coenzymeq10.htm
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| Â | Cerubidine Online, Description, Chemistry, Ingredients - Daunorubicin - RxList Monographs |
| | Dosage should be reduced in patients with impaired hepatic or renal function. | | | RxList only refers patients to online pharmacies certified by VIPPS, Verified Internet Pharmacy Practice Sites, a program administered by the National Association of Boards of Pharmacy which ensures that member pharmacies offering online prescription services are bona fide, fully licensed, and demonstrate "competent Internet/interstate pharmacy practices." | | | Get the latest health information from leading experts, delivered direct to your email box! |
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http://www.rxlist.com/cgi/generic2/daunorubicin.htm
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| Â | Characterization of Acidic Vesicles in Multidrug-resistant and Sensitive Cancer Cells by Acridine Orange Staining and ... |
| | Sharonov S, Chourpa I, Morjani H, Nabiev I, Manfait M (1994) Confocal spectral imaging: a new concept for studies of spatial distribution of antitumor drugs within living cancer cells. | | | Gervasoni JE, Fields SZ, Krishna S, Baker MA, Rosado M, Thuraisamy K, Hindenburg AA, Taub RN (1991) Subcellular distribution of daunorubicin in P-glycoprotein-positive and -negative drug resistant cell lines using laser-assisted confocal microscopy. | | | Hindenburg AA, Baker MA, Gleyzer E, Stewart VJ, Rosado M, Case N, Taub RN (1987) Effect of verapamil and other agents on the distribution of anthracyclines and on reversal of drug resistance. |
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http://www.jhc.org/cgi/content/full/45/9/1255
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| Â | The dnrO gene encodes a DNA-binding protein that regulates daunorubicin production in Streptomyces peucetius by ... |
| | The dnrO gene encodes a DNA-binding protein that regulates daunorubicin production in Streptomyces peucetius by controlling expression of the dnrN pseudo response regulator gene -- Otten et al. | | | mutant strain and resulted in the complete loss of daunorubicin | | | The dnrO gene encodes a DNA-binding protein that regulates daunorubicin production in Streptomyces peucetius by controlling expression of the dnrN pseudo response regulator gene |
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http://mic.sgmjournals.org/cgi/content/abstract/146/6/1457
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| Â | 272 - DAUNORUBICIN |
| | Once within the tumor environment, daunorubicin is released over time, enabling it to exert its antineoplastic activity. | | | Daunorubicin is most active in the S phase of cell division, but is not cycle phase-specific. | | | Daunorubicin is covered for the indications listed in the "ICD-9 Codes that Support Medical Necessity" section of this policy. |
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http://www.gamedicare.com/Policies/272.htm
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| Â | Synarc -- Biography |
| | Rahman, A.; Goodman, A.; Foo, W.; Harvey, J.; Smith, F.; Schein, P.: Clinical pharmacology of daunorubicin in phase I patients with solid tumors: Development of an analytical methodology for daunorubicin and its metabolites. | | | Harvey, J.; Bonnem, E.; Grady, K.; Goodman, A.; Schein, P.S.: A phase II study of daunorubicin in previously untreated patients with advanced colorectal carcinoma. | | | Harvey, J.; Goodman, A.; McFadden, M.; Schein, P.; Smith, F.: A phase I study of daunorubicin in advanced untreatable malignancies. |
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http://www.synarc.com/about/bio-schein.html
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| Â | Activation of Adriamycin by the pH-dependent Formaldehyde-releasing Prodrug Hexamethylenetetramine -- Swift et al. 2 ... |
| | Berman, E., and McBride, M. Comparative cellular pharmacology of daunorubicin and idarubicin in human multidrug-resistant leukemia cells.Blood, 79 :3267 –3273,1992. | | | Niitsu, N., Kasukabe, T., Yokoyama, A., Okabe-Kado, J., Yamamoto-Yamaguchi, Y., Umeda, M., and Honma, Y. Anticancer derivative of butyric acid (pivalyloxymethyl butyrate) specifically potentiates the cytotoxicity of doxorubicin and daunorubicin through the suppression of microsomal glycosidic activity.Mol. | | | Leng, F. F., Savkur, R., Fokt, I., Przewloka, T., Priebe, W., and Chaires, J. Base specific and regioselective chemical cross-linking of daunorubicin to DNA.J. Am. |
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http://mct.aacrjournals.org/cgi/content/full/2/2/189
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